Protein-bound uremic toxins as therapeutic targets for cardiovascular, kidney, and metabolic disorders by Shihan Zhang, Shasha Tang, Yalei Liu, Binghua Xue, Qinyuan Xie, Lingyun Zhao, Huijuan Yuan

Subjects: “…protein-bound uremic toxins…”
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Humoral Bone Morphogenetic Protein 2 Is Sufficient for Inducing Breast Cancer Microcalcification by Fangbing Liu, Nathalie Bloch, Kumar R. Bhushan, Alec M. De Grand, Eiichi Tanaka, Stephanie Solazzo, Pawel M. Mertyna, Nahum Goldberg, John V. Frangioni, Robert E. Lenkinski

“…Indeed, there is presently no short-latency, high-yield, syngeneic rodent model of the process. Bone morphogenetic protein 2 (BMP-2) is a key mediator of physiologic bone formation and pathologic vasculature calcification, but its role in breast cancer microcalcification is unknown. …”
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Proposal of a new nomenclature for introns in protein-coding genes in fungal mitogenomes by Shu Zhang, Yong-Jie Zhang

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Communication between DNA polymerases and Replication Protein A within the archaeal replisome by Markel Martínez-Carranza, Léa Vialle, Clément Madru, Florence Cordier, Ayten Dizkirici Tekpinar, Ahmed Haouz, Pierre Legrand, Rémy A. Le Meur, Patrick England, Rémi Dulermo, J. Iñaki Guijarro, Ghislaine Henneke, Ludovic Sauguet

“…Abstract Replication Protein A (RPA) plays a pivotal role in DNA replication by coating and protecting exposed single-stranded DNA, and acting as a molecular hub that recruits additional replication factors. …”
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An additive manufacturing approach for fabrication of agarose hydrogel structures for protein sorption application by Feng Cao, Hossein Najaf Zadeh, Klaudia Świacka, Jakub Maculewicz, Dan Bowles, Tim Huber, Don Clucas

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Cytokines and Chemokines in Pediatric Appendicitis: A Multiplex Analysis of Inflammatory Protein Mediators by S. Ali Naqvi, Graham C. Thompson, Ari R. Joffe, Jaime Blackwood, Dori-Ann Martin, Mary Brindle, Herman W. Barkema, Craig N. Jenne

“…Our primary objective was to determine levels of seven inflammatory protein mediators previously associated with intra-abdominal inflammation (C-reactive protein—CRP, procalcitonin—PCT, interleukin-6 (IL), IL-8, IL-10, monocyte chemoattractant protein-1—MCP-1, and serum amyloid A—SAA) in a cohort of children with suspected appendicitis. …”
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Leucine-Rich Repeat Protein Family Regulates Stress Tolerance and Development in Plants by Hao Zhiqi, Wang Tingyi, Chen Dongdong, Shen Lan, Zhang Guangheng, Qian Qian, Zhu Li

“…LRR proteins can be divided into two categories: those containing LRR domains along with other structural elements, which are further subdivided into five groups, LRR receptor-like kinases, LRR receptor-like proteins, nucleotide-binding site LRR proteins, LRR-extensin proteins, and polygalacturonase-inhibiting proteins, and those containing only LRR domains. …”
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Extracellular Cold-Inducible RNA-Binding Protein and Hemorrhagic Shock: Mechanisms and Therapeutics by Naureen Rashid, Zhijian Hu, Asha Jacob, Ping Wang

“…We recently discovered that cold-inducible RNA-binding protein released into the extracellular space acts as a DAMP. …”
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Effects of sika deer antler protein on immune regulation and intestinal microbiota in mice by Kaiyue Liu, Ke Zhang, Yang Yang, Ying Zong, Zhongmei He, Weijia Chen, Jianming Li, Rui Du

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Prognostic Value of Melanoma Inhibitory Activity Protein in Localized Cutaneous Malignant Melanoma by Angela Sandru, Eugenia Panaitescu, Silviu Voinea, Madalina Bolovan, Adina Stanciu, Sabin Cinca, Alexandru Blidaru

“…To identify if melanoma inhibitory activity (MIA) protein could represent a tool for selecting high risk early stages melanoma patients. …”
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Segmentation aware probabilistic phenotyping of single-cell spatial protein expression data by Yuju Lee, Edward L. Y. Chen, Darren C. H. Chan, Anuroopa Dinesh, Somaieh Afiuni-Zadeh, Conor Klamann, Alina Selega, Miralem Mrkonjic, Hartland W. Jackson, Kieran R. Campbell

“…Abstract Spatial protein expression technologies can map cellular content and organization by simultaneously quantifying the expression of >40 proteins at subcellular resolution within intact tissue sections and cell lines. …”
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Severe deviation in protein fold prediction by advanced AI: a case study by Jacinto López-Sagaseta, Alejandro Urdiciain

“…Abstract Artificial intelligence (AI) and deep learning are making groundbreaking strides in protein structure prediction. AlphaFold is remarkable in this arena for its outstanding accuracy in modelling proteins fold based solely on their amino acid sequences. …”
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Adaptability of high-protein barley genotypes under the conditions of the Volga-Vyatka region by I. Yu. Zaytseva, I. N. Shchennikova, L. V. Panikhina, E. V. Dyagileva

“…One of the urgent tasks is to develop high-yielding cultivars with good grain quality, thus reducing protein deficiency in farm animal feeds and meeting the need for fodder grain that increases every year. …”
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Procalcitonin and C-reactive protein - early predictors of low colorectal anastomotic leakage by Yu. A. Shelygin, M. A. Tarasov, M. A. Sukhina, I. V. Zarodnyuk, Ye. G. Rybakov

“…To determine diagnostic value of procalcitonin (PCT) and C-reactive protein (CRP) at anastomotic leakage (AL) following lower anterior resection (LAR) of the rectum. …”
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Jararaca GPIb-binding protein causes thrombocytopenia during Bothrops jararaca envenomation by Marcelo Larami Santoro, Ana Teresa Azevedo Sachetto, Jaqueline Gomes Rosa, Ricardo José Soares Torquato, Débora Andrade-Silva, Dilza Trevisan-Silva, Cynthia Zaccanini de Albuquerque, Solange M. T. Serrano, Vânia Gomes de Moura Mattaraia, Aparecida Sadae Tanaka, Maria Elisa Peichoto

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Blobby is a synaptic active zone assembly protein required for memory in Drosophila by J. Lützkendorf, T. Matkovic-Rachid, S. Liu, T. Götz, L. Gao, O. Turrel, M. Maglione, M. Grieger, S. Putignano, N. Ramesh, T. Ghelani, A. Neumann, N. Gimber, J. Schmoranzer, A. Stawrakakis, B. Brence, D. Baum, Kai Ludwig, M. Heine, T. Mielke, F. Liu, A. M. Walter, M. C. Wahl, S. J. Sigrist

“…Abstract At presynaptic active zones (AZs), scaffold proteins are critical for coordinating synaptic vesicle release and forming essential nanoarchitectures. …”
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Design and experimental validation of the action of small molecule-based inhibitors of the FADD protein by N. V. Ivanisenko, L. Hillert, V. A. Ivanisenko, I. N. Lavrik

“…FA DD is a key adaptor protein for the formation of the C D95 DISC and activation of caspase-8 in the receptor complex. …”
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Glucose-Sensing Carbohydrate Response Element-Binding Protein in the Pathogenesis of Diabetic Retinopathy by Christopher R. Starr, Assylbek Zhylkibayev, Oleg Gorbatyuk, Alli M. Nuotio-Antar, James Mobley, Maria B. Grant, Marina Gorbatyuk

“…Elevated expression of both proteins was observed in DR. This may have contributed to rod photoreceptor degeneration, as we observed diminished scotopic ERG amplitudes in caChREBP^RP mice at P35. …”
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Temporal ablation of the ciliary protein IFT88 alters normal brainwave patterns by Matthew R. Strobel, Yuxin Zhou, Liyan Qiu, Aldebaran M. Hofer, Xuanmao Chen

“…To help elucidate the role of cilia in neural activity, we temporally induced the ablation of IFT88, a gene encoding the intraflagellar transport 88 protein which is neccessary for ciliogenesis, in adult mice before performing memory-related behavioral assays and electroencephalogram/electromyogram (EEG/EMG) recordings. …”
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Toxic Effect of Cadmium on the Electrophoretic Protein Patterns of Gill and Muscle of Oreochromis mossambicus by K. Muthukumaravel, P. Kumarasamy, A. Amsath, M. Gabriel Paulraj

“…The numbers of protein fractions in the gills of test fishes were found to be lesser than the control fishes. …”
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