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2622
Efficacy and Safety of Bintrafusp Alfa, a Bifunctional Fusion Protein Targeting Transforming Growth Factor-β and Programmed Death-Ligand 1, Plus Chemotherapy in Patients With Stage IV NSCLC
Published 2025-01-01“…Patients with previously untreated metastatic NSCLC (cohorts A, B, and C) received bintrafusp alfa with chemotherapy as first-line treatment, whereas patients whose disease progressed on previous treatment with programmed cell death protein 1 or PD-L1 inhibitors (cohort D) received bintrafusp alfa with chemotherapy as second-line treatment. …”
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2623
Monitoring the Induction of Heat Shock Factor 1/Heat Shock Protein 70 Expression following 17-Allylamino-Demethoxygeldanamycin Treatment by Positron Emission Tomography and Optical Reporter Gene Imaging
Published 2012-01-01“…Good correspondence between reporter expression and HSP70 protein levels were observed. MicroPET imaging based on [ 124 I]iodide accumulation in pQHNIG70-transduced RG2 xenografts showed a significant 6.2-fold reporter response to 17-AAG, with a corresponding increase in tumor HSP70 and in tumor human sodium iodide symporter and green fluorescent protein reporter proteins. …”
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2624
Plasma C1q/TNF-Related Protein-3 (CTRP-3) and High-Mobility Group Box-1 (HMGB-1) Concentrations in Subjects with Prediabetes and Type 2 Diabetes
Published 2016-01-01“…To detect the association of C1q/TNF-related protein-3 (CTRP-3) and high-mobility group box-1 (HMGB-1) in subjects with prediabetes (pre-DM) and newly diagnosed type 2 diabetes (nT2DM). …”
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2626
A 16-week randomized controlled trial of a fish oil and whey protein-derived supplement to improve physical performance in older adults losing autonomy-A pilot study.
Published 2021-01-01“…<h4>Methods</h4>Participants were randomized to receive a supplement (EXP: 2g fish oil with 1500 IU vitamin D3 1x/d + 20-30g whey protein powder with 3g leucine 2x/d) or isocaloric placebo (CTR: corn oil + maltodextrin powder) for 16 weeks. …”
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2627
Molecular Mechanisms of Alzheimer’s Disease Induced by Amyloid-β and Tau Phosphorylation Along with RhoA Activity: Perspective of RhoA/Rho-Associated Protein Kinase Inhibitors for Neuronal Therapy
Published 2025-01-01“…Tau protein has also been identified as a significant factor in AD. …”
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2631
Fibroblast Growth Factor-2 and the HIV-1 Tat Protein Synergize in Promoting Bcl-2 Expression and Preventing Endothelial Cell Apoptosis: Implications for the Pathogenesis of AIDS-Associated Kaposi's Sarcoma
Published 2011-01-01“…Our previous work indicated that the angiogenic fibroblast growth factor (FGF)-2 and the Tat protein of HIV-1, both expressed in KS lesions of HIV-infected patients, synergize at inducing angioproliferative, KS-like lesions in mice. …”
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2632
Perbandingan Kadar Heat Shock Protein 90 dan Tumor Necrosis Factor-α Antara Kehamilan Preterm Dengan Ketuban Pecah Dini dan Tanpa Ketuban Pecah Dini
Published 2018-10-01“…Ketuban pecah dini (KPD) berkaitan dengan peningkatan kadar Heat Shock Protein 90 (HSP 90) dan Tumor Necrosis Factor-α (TNF-α) yang muncul akibat stres oksidatif. …”
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Supplementing the Diet of Hybrid Grouper (Epinephelus fuscoguttatus ♀ × E. lanceolatus ♂) with Compound Acidifier Is a Good Way to Alleviate Poor Intestinal Growth Caused by High Levels of Cottonseed Protein Concentrate
Published 2024-01-01“…In the FCA0.05 group, the results demonstrated a statistically significant increase in protein efficiency ratio, lipid efficiency ratio, and the activity of digestive enzymes in the intestine (P<0.05). …”
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2635
Dataset of SARS-CoV-2 spike protein receptor binding domain variants in complex with antigen-binding fragments targeting COVID-19 vaccine-referenced variantsModel Archive
Published 2025-02-01Subjects: “…Spike protein RBD…”
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Challenges and strategies in the soluble expression of CTA1-(S14P5)4-DD and CTA1-(S21P2)4-DD fusion proteins as candidates for COVID-19 intranasal vaccines.
Published 2024-01-01“…In this study, we constructed two fusion proteins containing CTA1, tandem repeat linear epitopes of the SARS-CoV-2 spike protein (S14P5 or S21P2), and DD. …”
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Sürdürülebilir ve Yeni Bir “Gıda” Alternatifi Olarak Yenilebilir Böcekler
Published 2023-03-01Subjects: “…alternatif protein kaynaklar…”
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The influence of hepatocyte growth factor on the proliferation and differentiation of stem cells
Published 2025-01-01Subjects: Get full text
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