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141
Simulations of pH and thermal effects on SARS-CoV-2 spike glycoprotein
Published 2025-02-01“…This study elucidates the complex interplay between pH and thermal effects on S-protein structures, with implications for its behavior under diverse conditions, and identifies the RBD as a primary region of the structural deviations. …”
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142
Ribosome pausing in amylase producing Bacillus subtilis during long fermentation
Published 2025-01-01“…Since these sites can neither be predicted based on codon specificity nor on secondary protein structures, we speculate that secondary mRNA structures are responsible for these translation pausing sites. …”
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143
Representing and Quantifying Conformational Changes of Kinases and Phosphatases Using the TSR-Based Algorithm
Published 2024-11-01“…In conclusion, this study presents an advanced computational methodology with significant advantages in not only representing and quantifying conformational changes of protein structures but also having the capability of directly linking protein structures to their functions.…”
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144
Predicting the impact of missense mutations on an unresolved protein’s stability, structure, and function: A case study of Alzheimer’s disease-associated TREM2 R47H variant
Published 2025-01-01“…However, AF2 falls short of predicting the effects of missense mutations on unresolved protein structures that may be informative to efforts in personalized medicine. …”
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145
Influence of Polymorphism on Glycosylation of Serum Amyloid A4 Protein
Published 2014-01-01“…These findings suggest that the changes in protein structures alter the efficiency of glycosylation in the SAA4 molecule. …”
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146
MPicker: visualizing and picking membrane proteins for cryo-electron tomography
Published 2025-01-01“…Abstract Advancements in cryo-electron tomography (cryoET) allow the structure of macromolecules to be determined in situ, which is crucial for studying membrane protein structures and their interactions in the cellular environment. …”
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147
AlphaFold2 and ESMFold: A large-scale pairwise model comparison of human enzymes upon Pfam functional annotation
Published 2025-01-01“…AlphaFold2 predicts protein structures from structural and functional knowledge. …”
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148
Nonprotein Structures from Mycobacteria: Emerging Actors for Tuberculosis Control
Published 2012-01-01“…For many decades, consistent to classical biochemistry, most studies regarding immunity to the tubercle bacilli focused mainly on protein structures. But the atypical, highly impermeable and waxy coat of mycobacteria captured the interest of structural biologists very early, allowing the description of amazing molecules, such as previously unknown carbohydrates or fatty acids of astonishing lengths. …”
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149
Effects of Ozone Treatments on the Physicochemical Changes of Myofibrillar Proteins from Silver Carp (Hypophthalmichthys molitrix) during Frozen Storage
Published 2017-01-01“…To2 did not significantly (P>0.05) affect these physicochemical properties, indicating that myofibrillar proteins structure was well maintained. Consequently, To1 significantly (P>0.05) decreased breaking force of surimi gels while To2 did not significantly (P>0.05) affect gel breaking force. …”
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150
Effects of Drying Temperature and Relative Humidity on Quality Properties of Chinese Dried Noodles
Published 2020-01-01“…The influence of the drying conditions on protein structural properties and its impact on Chinese dried noodles (CDN) quality properties is addressed in this study. …”
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151
Effect of Whey Protein Changes on Milk Flavor and Sensory Characteristics During Heating
Published 2024-12-01“…The results showed that higher temperatures changed the secondary milk whey protein structures and gradually increased α-lactalbumin, β-lactoglobulin, and lactoferrin denaturation in the milk. …”
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152
Advancements in electron paramagnetic resonance (EPR) spectroscopy: A comprehensive tool for pharmaceutical research
Published 2024-12-01“…Electron paramagnetic resonance (EPR) spectroscopy has long been established across various scientific disciplines for characterizing organic radicals, organometallic complexes, protein structures and dynamics, polymerization processes, and radical degradation phenomena. …”
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153
Genetic Algorithm-Enhanced Direct Method in Protein Crystallography
Published 2025-01-01“…We systematically tested the method on 15 protein structures from different space groups with diffraction resolutions of 1.35∼2.5 Å. …”
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154
Future trends in plant-based meat: Consumer perception, market growth and health benefits
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155
Allostery can convert binding free energies into concerted domain motions in enzymes
Published 2024-11-01“…However, understanding enzymes require unravelling the intricate dynamic interplay between dynamics, conformational substates, and multiple protein structures. Here, we use single-molecule nanopore analysis to investigate the catalytic conformational changes of adenylate kinase (AK), an enzyme that catalyzes the interconversion of various adenosine phosphates (ATP, ADP, and AMP). …”
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156
Characterization of the C-terminal tail of the Arc protein.
Published 2020-01-01“…We compared the sequences of Arc proteins in different mammal species and found that the amino-acid composition in the C-terminal tail region has a significantly higher degree of variation rate than the rest of the protein. Structural prediction programs suggested that the C-terminal tail is structurally disordered. …”
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157
Effectiveness of E-Learning in the Field of Biochemistry
Published 2024-12-01“…The learning objectives laid down for the course were specific, measurable, and generic and included topics, such as enzyme kinetics, metabolic pathways, and protein structures. These were grouped into topic-based weekly work schedule. …”
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158
Impact of choline choride and sugar natural deep eutectic solvents on structure and functionality of treebean (Parkia timoriana) seed protein
Published 2025-01-01“…These results highlight the ability of NADES to stabilize protein structures while maintaining functionality under processing conditions. …”
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159
Spectroscopic investigation of the ultrasound impacts on the molecular structures of blood proteins
Published 2025-06-01“…This study explores how LFUWs alter blood protein structures, utilizing ultraviolet-visible (UV–vis), Raman, and Fourier transform infrared (FTIR) spectroscopies. …”
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160
Effect of Ultrasonic Treatment on the in Vitro Digestibility Properties of Black Bean Protein
Published 2025-02-01“…Furthermore, the effect of ultrasonication on the black bean protein structural properties was analyzed by scanning electron microscopy, infrared spectroscopy, fluorescence spectroscopy. …”
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