Showing 41 - 60 results of 182 for search '"protein structure"', query time: 0.08s Refine Results
  1. 41

    Influence of Vacuum Precooling Pressure on SOD Enzyme Activity of Fresh Lycium barbarum and Molecular Dynamics Simulation by Hongbo ZHANG, Ningbo KANG, Lianghuan ZHOU, Jun ZHANG, Qianjin QU

    Published 2025-01-01
    “…The activity of SOD enzyme protein decreased under 1100 Pa, the protein structure was damaged, and binding pocket became smaller. …”
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  2. 42

    Exploration of predictive markers associated with primary angle-closure glaucoma risk in companion dogs using genomic information by Ji Hyun Jun, Gwang Hyeon Lee, Zultsetseg Byambasuren, Hong Sik Kong

    Published 2024-12-01
    “…To assess the impact of non-synonymous SNP (nsSNPs), functional analysis of candidate genes, Hazard Assessment, and protein structure prediction were conducted. Sequencing for SNP validation involved samples from 95 dogs of ten breeds with reported domestic and international glaucoma cases. …”
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  3. 43

    Detection and Phylogenetic Analysis of an Exotic Strain of Porcine Epidemic Diarrhea Virus and Its Effect on an Affected Herd Immunized Against the Endemic Strain in Thailand by Christopher James Stott, Patumporn Jermsutjarit, Pornchai Pornpanom, Hongyao Lin, Angkana Tantituvanont, Dachrit Nilubol

    Published 2025-01-01
    “…A unique insertion in the protein structure of the novel <b>G2b</b> strain led to the identification of a new epitope and potential changes in viral properties. …”
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  4. 44

    Computational Analysis of nsSNPs of ADA Gene in Severe Combined Immunodeficiency Using Molecular Modeling and Dynamics Simulation by Soukaina Essadssi, Al Mehdi Krami, Lamiae Elkhattabi, Zouhair Elkarhat, Ghita Amalou, Houria Abdelghaffar, Hassan Rouba, Abdelhamid Barakat

    Published 2019-01-01
    “…In this study, we performed a bioinformatics analysis of the human ADA gene to identify potentially harmful nonsynonymous SNPs and their effect on protein structure and stability. Using eleven prediction tools, we identified 15 nsSNPs (H15D, H15P, H17Q, H17Y, D19N, T26I, G140E, C153F, A183D, G216R, H258Y, C262Y, S291L, S291W, and K34OE) as harmful. …”
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  5. 45

    Principles of Medical Biochemistry / by Meisenberg, Gerhard

    Published 2017
    Table of Contents: “…Introduction to biomolecules -- Introduction to protein structure -- Oxygen-binding proteins : hemoglobin and myoglobin -- Enzymatic reactions -- Coenzymes -- DNA, RNA, and protein synthesis -- The human genome -- Protein targeting and proteostasis -- Introduction to genetic diseases -- Viruses -- DNA technology -- Biological membranes -- The cytoskeleton -- The extracellular matrix -- Extracellular messengers -- Intracellular messengers -- Plasma proteins -- Defense mechanisms -- Cellular growth control and cancer -- Digestive enzymes -- Introduction to metabolic pathways -- Glycolysis, tricarboxylic acid cycle, and oxidative phosphorylation -- Oxygen deficiency and oxygen toxicity -- Carbohydrate metabolism -- The metabolism of fatty acids and triglycerides -- The metabolism of membrane lipids -- Lipid transport -- Amino acid metabolism -- Metabolism of iron and heme -- The metabolism of purines and pyrimidines -- Micronutrients -- Integration of metabolism.…”
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  6. 46

    Variation in mitochondrial genome primary sequence among whole-genome-sequenced strains of Neurospora crassa by K. McCluskey

    Published 2012-06-01
    “…Most of the limited variability in mitochondrial genome sequence is neutral with regard to protein structure. Despite the fact that the mitochondrial genome is present in multiple copies per cell, many of the polymorphisms were homozygous within each strain. …”
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  7. 47

    Proteomic and N-glycosylation analysis of fertile egg white during storage and incubation in chickens by Daqing Dai, Xiqiong Wang, Kexin Wu, Fangren Lan, Jiaming Jin, Wenxin Zhang, Chaoliang Wen, Junying Li, Ning Yang, Congjiao Sun

    Published 2025-01-01
    “…We found that the differential N-glycoproteins in the early stage of storage were mainly related to protein structure changes, antibacterial activity, and cell proliferation, and that there were more protease inhibitors in egg whites, which decreased in the later stage of storage. …”
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  8. 48

    Protein-Lipid Interactions in Different Meat Systems in the Presence of Natural Antioxidants – a Review by Hęś Marzanna

    Published 2017-03-01
    “…It was also noted that the conformation of the protein structure, the surface charge, the affinity, and the accessibility of reactive groups affect the intensity of these interactions.…”
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  9. 49

    Core-shell nanofibers as drug delivery systems by Zupančič Špela

    Published 2019-06-01
    “…Several studies have shown that core-shell nanofibers have some advantages over monolithic nanofibers, such as better drug, protein, gene or probiotic incorporation into the nanofibers, greater control over drug release, and maintenance of protein structure and activity during electrospinning. …”
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  10. 50

    NOVEL MUTATIONS IN THE NON-STRUCTURE PROTEIN 2 OF SARS-CoV-2 by Mohsen Nakhaei, Zohreh-Al-Sadat Ghoreshi, Mohammad Rezaei Zadeh Rukerd, Hedyeh Askarpour, Nasir

    Published 2023-10-01
    “…Bioinformatics analysis was conducted to investigate the effect of mutations on protein structure, prediction of homology models, phylogeny tree. …”
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  11. 51

    Mutation in the COL2A1 gene is associated with acetabular dysplasia by Miaomiao Xin, Xin Guan, Xin Guan, Jiangfei Yang, Yi Li, Zhentao Man, Hongsheng Sun, Min Fu

    Published 2025-01-01
    “…Bioinformatic analysis indicated that the c.823C &gt; T (p.Arg275Cys) variant is pathogenic, and structural modeling demonstrated that the substitution of arginine with cysteine at residue 275 altered the protein structure.ConclusionOur findings highlight the diagnostic utility of NGS in identifying precise genetic causes of DDH. …”
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  12. 52

    Prediction of Deleterious Nonsynonymous Single-Nucleotide Polymorphism for Human Diseases by Jiaxin Wu, Rui Jiang

    Published 2013-01-01
    “…As a typical type of genetic variation, nonsynonymous single-nucleotide polymorphisms (nsSNPs) occurring in protein coding regions may alter the encoded amino acid, potentially affect protein structure and function, and further result in human inherited diseases. …”
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  13. 53

    A Biomimetic Approach for the Creation of Two-Dimensional Microscale Surface Patterns: Creation of Isolated Immunological Synapses by Eric Stern, David J. Mooney, Tarek M. Fahmy

    Published 2009-01-01
    “…We demonstrate our approach with a biomimetic structure inspired by the immunological synapse, a cell-cell interfacial structure characterized by two concentric rings of proteins: an outer adhesion protein structure and an inner recognition ligand core. …”
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  14. 54

    Physical Aspects of Viral Membrane Fusion by Laura Wessels, Keith Weninger

    Published 2009-01-01
    “…Here we focus our discussion on the key dynamical aspects of fusion protein structure, along with some of the experimental and computational techniques presently being used to investigate viral-mediated membrane fusion.…”
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  15. 55
  16. 56

    Bioinformatics Interpretation of Exome Sequencing: Blood Cancer by Jiwoong Kim, Yun-Gyeong Lee, Namshin Kim

    Published 2013-03-01
    “…By comparing with previous somatic mutation profiles, we had concluded that the provided data originated from acute myeloid leukemia. Protein structure modeling showed that somatic mutations in IDH2, RASGEF1B, and MSH4 can affect protein structures.…”
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  17. 57

    Using In Silico Methods to Identify Protein Tyrosine Kinase A (PtkA) Homolog in Non-Tuberculous Mycobacteria (NTM) by Swati Jaiswal, Sanjay Kumar

    Published 2024-11-01
    “…In this article, we have employed tools like BLAST (Basic Local Alignment Search Tool), protein structure databases, and the NTM database to identify PtkA homologs in NTM genomes, providing a foundation for further studies.…”
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  18. 58

    Enhanced sampling of protein conformational changes via true reaction coordinates from energy relaxation by Huiyu Li, Ao Ma

    Published 2025-01-01
    “…Furthermore, our method uses a single protein structure as input, enabling predictive sampling of conformational changes. …”
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  19. 59

    An outlook on structural biology after AlphaFold: tools, limits and perspectives by Serena Rosignoli, Maddalena Pacelli, Francesca Manganiello, Alessandro Paiardini

    Published 2025-02-01
    “…AlphaFold and similar groundbreaking, AI‐based tools, have revolutionized the field of structural bioinformatics, with their remarkable accuracy in ab‐initio protein structure prediction. This success has catalyzed the development of new software and pipelines aimed at incorporating AlphaFold's predictions, often focusing on addressing the algorithm's remaining challenges. …”
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  20. 60