Comparative Transcriptome Analysis Reveals Molecular Defensive Mechanism of Arachis hypogaea in Response to Salt Stress by Hao Zhang, Xiaobo Zhao, Quanxi Sun, Caixia Yan, Juan Wang, Cuiling Yuan, Chunjuan Li, Shihua Shan, Fengzhen Liu

“…Peanut (Arachis hypogaea L.) is one of the most important crops for vegetable oil, proteins, minerals, and vitamins in the world. Therefore, it is of importance to understand the molecular mechanism of peanut against salt stress. …”
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Sex Differences in the Allele Distribution of PGLYRP2 Variant rs892145 in Parkinson’s Disease by Caroline Ran, Karin Wirdefeldt, Olof Sydow, Per Svenningsson, Rochellys Diaz Heijtz

“…The microbiota-gut-brain axis is hypothesized to play a role in the pathophysiology of PD, and peptidoglycan recognition proteins (PGLYRPs), which modulate the gut microbiota, are, therefore, relevant candidate genes for PD. …”
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Methods of massive parallel reporter assays for investigation of enhancers by S. E. Romanov, D. A. Kalashnikova, P. P. Laktionov

“…In combination with high-throughput studies focused on the genome-wide distribution of epigenetic marks, regulatory proteins and the spatial structure of chromatin, this significantly expands the understanding of the principles of epigenetic regulation of genes and allows potential regulatory elements to be searched for in silico. …”
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Renal Tissue-Derived Exosomal miRNA-34a in Diabetic Nephropathy Induces Renal Tubular Cell Fibrosis by Promoting the Polarization of M1 Macrophages by Shuai Zheng, Yi Zeng, Liqing Chu, Taiyang Gong, Sihong Li, Min Yang

“…Q-PCR and western blot were undertaken to detect related RNA and proteins. Results. An animal model of diabetic nephropathy was successfully constructed. …”
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Senescence-Associated Molecular and Epigenetic Alterations in Mesenchymal Stem Cell Cultures from Amniotic Fluid of Normal and Fetus-Affected Pregnancy by Jūratė Savickienė, Sandra Baronaitė, Aistė Zentelytė, Gražina Treigytė, Rūta Navakauskienė

“…These differences correlated with changes in the level of chromatin modifiers (DNMT1 and HDAC1) and polycomb group proteins (EZH2, SUZ12, and BMI1) paralleling with changes in the expression of repressive histone marks (H3K9me3 and H3K27me3) and stemness markers (Oct4, Nanog, Sox2, and Rex1). …”
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Salt stress and its eco-friendly management using biostimulants in grain legumes: a review by Narayan Singh, Vasudha Maurya, Kriti Gupta, Indu Sharma, Ashutosh Sharma, Rahul Kumar

“…Abstract Grain legumes are a rich source of dietary proteins and hence are essential for achieving food and nutritional security, worldwide. …”
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A green route of antibacterial films production from shrimp (Penaeus monodon) shell waste biomass derived chitosan: Physicochemical, thermomechanical, morphological and antimicrobi... by Md. Mahmudur Rahman, Mohd. Maniruzzaman, Ripon Kumar Saha

“…Whereas the highly active chitosan were extracted from shrimp (Penaeus monodon) shells by conducting demineralization, de-proteinization, and deacetylation reaction. The chitosan-acetate films were fabricated by using the EIPS operation to enhance their overall properties. …”
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Comparative Transcriptomic Analysis of Root Cadmium Responses in Two Chinese Rice Cultivars Yuzhenxiang and Xiangwanxian 12 by Shangdu Zhang, Zhenliang Luo, Xiang Wu, Bangzhi Shi, Huidan Jiang, Leliang Zhou, Lianyang Bai

“…Among these genes, 7 genes, such as Os06g0196300 (OsJ_019618), Os07g0570700 (OsJ_24808), ADI1, GDCSH, HSFB2C, PEX11-4, and CLPB1, possessed higher degree nodes with each other, through interaction analysis by the STRING (search tool for the retrieval of interacting genes/proteins) software, suggesting that they might play vital roles in Cd response. …”
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Methods of yeast genome editing by A. S. Rozanov, V. N. Shlyahtun, L. A. Tekutieva, O. M. Son, S. V. Sizova, S. E. Peltek

“…The most prominent examples are the proteins used for directed DNA editing. For a long time, yeast genome engineering was based on the yeasts’ system of homologous recombination. …”
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Immunoinformatic strategy for developing multi-epitope subunit vaccine against Helicobacter pylori. by Md Nahian, Md Rasel Khan, Fabiha Rahman, Hossain Mohammed Reza, Imren Bayil, Tanjum Ahmed Nodee, Tabassum Basher, Mostafizur Rahaman Sany, Rabeya Najnin Munmun, S M Ariful Habib, Lincon Mazumder, Mrityunjoy Acharjee

“…In this study, we employed an immunoinformatic strategy to design a set of candidate multi-epitope subunit vaccines by combining the most potent B and T cell epitopes from three targeted antigenic proteins (BabA, CagA, and VacA). Out of the 12 hypothetical vaccines generated, two (HP_VaX_V1 and HP_VaX_V2) were found to be strongly immunogenic, non-allergenic, and structurally stable. …”
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Protective effects of small RNAs encapsulated in Artemisia Capillaris-derived exosomes against non-alcoholic fatty liver disease by Min Xu, Longjun Ma, Hongwei Liang, Wei Tang, Shouyong Gu

“…Additionally, the expression levels of proteins and RNAs associated with lipogenesis and inflammation were analyzed.ResultsThe NAFLD mouse model exhibited notable liver damage, including lipid deposition and inflammatory responses. …”
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Transcriptomic Response in Pseudomonas aeruginosa towards Treatment with a Kaempferol Isolated from Melastoma malabathricum Linn Leaves by Mourouge Saadi Alwash, Wan Syaidatul Aqma, Wan Yaacob Ahmad, Nazlina Ibrahim

“…Furthermore, KF also increased the expression of genes associated with ATP-binding cassette transporters, flagella, type III secretion system proteins, and DNA replication and repair, which may further influence nutrient uptake, motility, and growth. …”
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Transplantation of Rat Mesenchymal Stem Cells Overexpressing Hypoxia-Inducible Factor 2α Improves Blood Perfusion and Arteriogenesis in a Rat Hindlimb Ischemia Model by Weifeng Lu, Xiaoli Chen, Yi Si, Shichai Hong, Zhengyu Shi, Weiguo Fu

“…Compared with the injection of PBS or rMSCs, transplantation of rMSCsHIF-2α significantly improved blood perfusion, increased the number of vessel branches in the muscle of the ischemic hindlimb, and improved the foot mobility of the ischemic hindlimb (all P<0.05). rMSCHIF-2α transplantation also markedly increased the expression of proangiogenic factors VEGF, bFGF, and SDF1 and Notch signaling proteins including DII4, NICD, Hey1, and Hes1, whereas it reduced the expression of proapoptotic factor Bax in the muscle of the ischemic hindlimb. …”
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The opposite association of HRAS and KRAS mutations with clinical variables of bladder cancer by M. P. Smal, A. I. Rolevich, T. N. Nabebina, S. A. Krasny, R. I. Goncharova

“…HRAS, KRAS and NRAS gene products belong to the superfamily of small GTPases. These proteins regulate cellular response to extracellular stimuli by means of activation of different signaling pathways. …”
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Uncovering the Beneficial Role of <i>Limosilactobacillus fermentum</i> E7 Exhibiting Antioxidant Activity in Ameliorating DSS-Induced Ulcerative Colitis in a Murine Model by Hongyan Zhang, Hailing Wang, Yue Li, Yue Leng, Ke Lin, Dayong Ren

“…Finally, E7 increased the expression of tight junction proteins in colon tissues. Conclusions: E7 showed superior efficacy to other probiotics in alleviating UC, offering novel therapeutic prospects for safer and effective management of UC.…”
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Étude multicritères sur le passage à un régime sans fruits chez les Cébidés et les Cercopithécidés by Flore Viallard, Sébastien Lefebvre, Alexandre Petry, Irène Vonfeld, Benoît Quintard

“…The initial diet included cultivated fruits and vegetables and some extras (cereals, animal and vegetable proteins) and was higher in non-structural carbohydrates, in particular sugar, than recommended in husbandry guidelines. …”
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Methionine-induced regulation of growth, secondary metabolites and oxidative defense system in sunflower (Helianthus annuus L.) plants subjected to water deficit stress. by Gull Mehak, Nudrat Aisha Akram, Muhammad Ashraf, Prashant Kaushik, Mohamed A El-Sheikh, Parvaiz Ahmad

“…While a significant increase was observed due to water deficiency in relative membrane permeability (RMP), malondialdehyde (MDA), total soluble proteins (TSP), total soluble sugars (TSS), ascorbic acid (AsA) and activity of peroxidase (POD). …”
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Expression of the transcription factor encoding gene <i>StTCP23</i> in potato plants infected with the tuber spindle viroid by N. V. Mironenko, A. S. Orina, N. M. Lashina, О. S. Afanasenko

“…PSTVd is a circular, single-stranded RNA molecule that does not code for proteins. Symptoms caused by PSTVd lead to a significant reduction in tuber yield or death of the plant. …”
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The Expression of Thymic AQP7 and Perilipin 1 (PLIN1) in Rats Fed a High-Fructose Diet is Modified by Voluntary Physical Activity by Jülide Tozkır, Nihayet Fırat, Ebru Göncü, Onur Ersoy, Pınar Tayfur, Orkide Palabıyık

“…Objective: Aquaporins (AQPs) are a large family of proteins that help transport water and small molecules. …”
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A review of the Bovis Calculus’s intervention mechanism and clinical application in ischemic stroke by Ke Xu, Bowen Deng, Tongtong Jia, Mihong Ren, Hai Chen, Jing Zhang, Jinlin Guo, Yong Li, Jian Wang

“…Information on Chinese medicine preparations and clinical reports was also integrated to provide an overview of modern applications and safety considerations.ResultsBC mainly includes chemical components such as bile pigments, bile acids, cholesterol, proteins amino acids, and trace elements. Additionally, the efficacy of BC in treating cerebral ischemia/reperfusion injury (CI/RI) is certain, particularly due to the components of bile pigments, bile acids, and amino acids that can interfere with the enzymatic cascade reaction of CI/RI through multiple components, targets, and pathways. …”
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