Minerals, Toxic Heavy Metals, and Antioxidant Properties of Honeys from Bangladesh by Sudip Paul, Md. Sakib Hossen, E. M. Tanvir, Rizwana Afroz, Delwar Hossen, Sagarika Das, Nikhil Chandra Bhoumik, Nurul Karim, Farha Matin Juliana, Siew Hua Gan, Md. Ibrahim Khalil

“…The results of antioxidant analysis based on phenolics, flavonoids, ascorbic acid, reducing sugar, and proteins (as nonphenolic antioxidants) revealed that multifloral raw honey samples contain significantly higher levels of reducing agents than monofloral and commercial brand honeys. …”
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PARP‐1 Inhibition Increases Oxidative Stress in Ets‐1‐Expressing MDA‐MB‐231 Breast Cancer Cells by Magalie Hervieu, Arnaud J. Legrand, Emilie Floquet, Thierry Idziorek, Corentin Spriet, Didier Monté, Vincent Villeret, Marc Aumercier, Souhaila Choul‐li

“…Next, we evaluated PARP‐1 inhibition effect on oxidative DNA damage in Ets‐1‐overexpressing and Ets‐1‐non‐expressing breast cancer cells and we showed that PARPi led only Ets‐1‐overexpressing cells to accumulate it, which triggers the DNA damage response as revealed by the increase in the level of a panel of DNA damage‐related proteins. Importantly, we demonstrated that PARPi increased reactive oxygen species (ROS), only in Ets‐1‐overexpressing cells and this is accompanied by upregulation of p47phox expression, a subunit of the NAPDH oxidase (NOX). …”
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The grapevine ABC transporter B family member 15 is a trans-resveratrol transporter out of grapevine cells by Ascensión Martínez-Márquez, Ascensión Martínez-Márquez, Viviana Martins, Susana Sellés-Marchart, Susana Sellés-Marchart, Hernâni Gerós, Purificación Corchete, Roque Bru-Martínez, Roque Bru-Martínez, Roque Bru-Martínez

“…VvABCB15-YFP fusion proteins in Nicotiana leaf showed localization in the plasma membrane, consistent with a functional role in trans-resveratrol transport. …”
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The role of lipids and lipids lowering drugs in human papillomavirus (HPV) and HPV-associated cancers by Ehsan Shabani, Aida Hasanzadi, Omer Qutaiba B. Allela, Radhwan Abdul Kareem, Riyad E. Abed, Ali M. Ali Al-Nuaimi, Zainab H. Athab, Shiva Khodarahmi

“…One of the most noticeable metabolic abnormalities in cancer is lipid metabolism reprogramming, in which cancer cells dysregulate lipid metabolism to obtain sufficient energy, building blocks for cell membranes, and signaling molecules necessary for invasion, metastasis, proliferation, and survival. Moreover, HPV proteins' stimulation of lipid production in infected cells will probably have a significant effect on oncogenesis. …”
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Peripheral mitochondrial transplantation alleviates diabetes-associated cognitive dysfunction by suppressing cuproptosis by Juan Hu, Qiao Li, Shiqiu Jiang, Yingying Deng, Lan Yang, Mengyu Du, Shuxuan He, Fuxing Xu, Chaoying Yan, Wei Gao, Yansong Li, Yaomin Zhu

“…In this research, the study delved into the expression levels of cuproptosis-associated proteins FDX1, LIAS, and DLAT, as well as the copper content in both type 2 diabetes mellitus (T2DM) mice and primary neuronal cells exposed to high glucose and palmitic acid (HG/Pal). …”
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Genomic landscape of head and neck cancer in Asia: A comprehensive meta-analysis of 1016 samples by Srikanth S. Manda, Nafisa Arfa, Neha Sharma, Aparna R. Parikh, Thomas J. Roberts, Sewanti Limaye, Venkataraman Ramachandran, Kumar Prabhash, Moni A. Kuriakose, Prashant Kumar

“…Notably, the RAF family proteins, enriched in both Indian and Chinese cohorts, present potential therapeutic targets for RAF inhibitors like Vemurafenib. …”
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Chronic fetal hypoxia and antenatal Vitamin C exposure differentially regulate molecular signalling in the lung of female lambs in early adulthood by Erin V. McGillick, Erin V. McGillick, Sandra Orgeig, Beth J. Allison, Kirsty L. Brain, Melanie R. Bertossa, Stacey L. Holman, Ashley S. Meakin, Michael D. Wiese, Youguo Niu, Nozomi Itani, Katie L. Skeffington, Christian Beck, Kimberly J. Botting-Lawford, Janna L. Morrison, Janna L. Morrison, Dino A. Giussani

“…Lung tissue expression of genes and proteins regulating oxidative stress, mitochondrial function, hypoxia signalling, glucocorticoid signalling, surfactant maturation, inflammation and airway remodelling were measured.ResultsChronic fetal hypoxia upregulated lung expression of markers of prooxidant, surfactant lipid transport and airway remodelling pathways in early adulthood. …”
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Selective ATP-Binding Cassette Subfamily C Gene Expression and Proinflammatory Mediators Released by BEAS-2B after PM2.5, Budesonide, and Cotreated Exposures by Jarline Encarnación-Medina, Rosa I. Rodríguez-Cotto, Joseph Bloom-Oquendo, Mario G. Ortiz-Martínez, Jorge Duconge, Braulio Jiménez-Vélez

“…ATP-binding cassette subfamily C (ABCC) genes code for phase III metabolism proteins that translocate xenobiotic (e.g., particulate matter 2.5 (PM2.5)) and drug metabolites outside the cells. …”
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Discovery of a novel highly specific, fully human PSCA antibody and its application as an antibody-drug conjugate in prostate cancer by Xiaojie Chu, Seungmin Shin, Du-San Baek, Liyong Zhang, Alex Conard, Megan Shi, Ye-Jin Kim, Cynthia Adams, Maggie Hines, Xianglei Liu, Chuan Chen, Zehua Sun, Dontcho V. Jelev, John W. Mellors, Dimiter S. Dimitrov, Wei Li

“…The structure-based affinity maturation yielded a high-affinity binder, F12, which is highly specific and does not bind to 6,000 human membrane proteins based on a membrane proteome array assay. …”
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Synthesis and structural insights of bis(2-methoxy-6-{[(2-methylpropyl)imino]methyl}phenolato) nickel (II) complex through DFT and docking investigations by K. Jayachandiran, Sv. Esha, M. Savitha Lakshmi, S. Mahalakshmi, S. Arockiasamy

“…Docking studies revealed that the molecule binds well with proteins such as PDB: 2W9H for Dihydrofolate Reductase of S.aureus as shown by its binding energy of -8.62 kcal.mol− 1.…”
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Genome-Wide Identification and Expression Analysis of the <i>ALDH</i> Gene Family in <i>Sinonovacula constricta</i> Bivalve in Response to Acute Hypersaline Stress by Jianing Yu, Biao Wu, Yinghui Dong, Zhihua Lin, Hanhan Yao

“…These genes are located on eight chromosomes, with tandem duplications observed on chromosome 10; they encode mostly acidic and hydrophilic proteins. Among them, <i>ScALDH18A1</i> contains a conserved P5CS domain that is implicated in proline synthesis and osmotic regulation. …”
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LncRNA CASC15 upregulates cyclin D1 by downregulating miR-365 in laryngeal squamous cell carcinoma to promote cell proliferation by Minhui Zhu, Caiyun Zhang, Peng Zhou, Shicai Chen, Hongliang Zheng

“…The expression levels of proteins and mRNAs were determined by Western blotting analysis and qRT-PCRs, respectively. …”
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Unraveling the function of TSC1-TSC2 complex: implications for stem cell fate by Shuang Wang, Ruishuang Ma, Chong Gao, Yu-Nong Tian, Rong-Gui Hu, Han Zhang, Lan Li, Yue Li

“…These genes produce proteins that regulate mTORC1 activity, essential for cell function and metabolism. …”
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Small Interfering RNA Targeted to ASPP2 Promotes Progression of Experimental Proliferative Vitreoretinopathy by Xiao-Li Chen, Yu-Jing Bai, Qin-Rui Hu, Shan-Shan Li, Lv-Zhen Huang, Xiao-Xin Li

“…Apoptosis-stimulating proteins of p53 (ASPP2) have recently been reported to participate in EMT. …”
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Reconstitution of human DNA licensing and the structural and functional analysis of key intermediates by Jennifer N. Wells, Lucy V. Edwardes, Vera Leber, Shenaz Allyjaun, Matthew Peach, Joshua Tomkins, Antonia Kefala-Stavridi, Sarah V. Faull, Ricardo Aramayo, Carolina M. Pestana, Lepakshi Ranjha, Christian Speck

“…Here, we report the reconstitution of human DNA licensing using purified proteins. We showed that the in vitro reaction is specific and results in the assembly of high-salt resistant hMCM2-7 double-hexamers. …”
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Expression of Glutathione Peroxidase and Glutathione Reductase and Level of Free Radical Processes under Toxic Hepatitis in Rats by Igor Y. Iskusnykh, Tatyana N. Popova, Aleksander A. Agarkov, Miguel Â. A. Pinheiro de Carvalho, Stanislav G. Rjevskiy

“…Western blot analysis revealed that the amounts of hepatic Gpx1 and Gsr proteins increased considerably after CCl4 administration. …”
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Exosomes in neuron-glia communication: A review on neurodegeneration by Naeimeh Akbari-Gharalari, Sina Khodakarimi, Farshad Nezhadshahmohammad, Mohammad Karimipour, Abbas Ebrahimi-Kalan, Jiagian Wu

“…Despite their small size, they carry diverse cargo, including RNA, proteins, and lipids. Internalization by recipient cells raises concerns about potential disruptions to cellular functions. …”
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Structural basis of FpGalNase and its combination with FpGalNAcDeAc for efficient A-to-O blood group conversion by Meiling Zhou, Kaishan Luo, Chao Su, Yan Sun, Zuyan Huang, Shuo Ma, Xun Gao, Jiwei Wang, Chen Zhang, Pengcheng Han, Guoqiu Wu

“…Additionally, we engineered two fusion proteins, FpGalNAcDeAc-FpGalNase and FpGalNase-FpGalNAcDeAc, which showed a 28-fold increase in catalytic efficiency compared to the enzyme mixture. …”
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Advancing the Fight Against Cervical Cancer: The Promise of Therapeutic HPV Vaccines by Qian Zheng, Misi He, Zejia Mao, Yue Huang, Xiuying Li, Ling Long, Mingfang Guo, Dongling Zou

“…Currently, there are no approved therapeutic HPV vaccines worldwide; however, active progress is being made in clinical research and development using multiple platforms such as peptides, proteins, DNA, RNA, bacterial vectors, viral vectors, and cell-based, each offering relative advantages and limitations for delivering HPV antigens and generating targeted immune responses. …”
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AAV-KLF7 Promotes Descending Propriospinal Neuron Axonal Plasticity after Spinal Cord Injury by Wen-Yuan Li, Ying Wang, Feng-Guo Zhai, Ping Sun, Yong-Xia Cheng, Ling-Xiao Deng, Zhen-Yu Wang

“…In vitro, KLF7 and target proteins were successfully elevated and axonal outgrowth was enhanced. …”
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