Differential Proteomic Analysis Predicts Appropriate Applications for the Secretome of Adipose-Derived Mesenchymal Stem/Stromal Cells and Dermal Fibroblasts by Stefania Niada, Chiara Giannasi, Alice Gualerzi, Giuseppe Banfi, Anna Teresa Brini

“…Out of 967 quantified proteins, 34 and 62 factors were found preponderantly or exclusively secreted by ASCs and DFs, respectively. …”
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Reduced Occurrence of Gastrointestinal Symptoms in Chinese Infants Fed Minimally Processed Commercially Available Formula: A Cross-Sectional Observational Study by Xiao Yang Sheng, Vanitha Buthmanaban, Glenn A. A. van Lieshout, Panam Parikh

“…Healthy Chinese infants consuming one of four commercially available infant formulas (IF) were assessed on the occurrence of gastrointestinal symptoms associated with suboptimal digestion of processed milk proteins. The IF differed in blocked lysine (BL) levels, a proxy indicator of heat processing as well as the nutritional quality of milk. …”
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Second-generation BRAF inhibitor Encorafenib resistance is regulated by NCOA4-mediated iron trafficking in the drug-resistant malignant melanoma cells by Ceyda Colakoglu Bergel, Isil Ezgi Eryilmaz, Gulsah Cecener, Unal Egeli

“…Autophagic Beclin and LC3 proteins, and AKT signaling increased in the A375-R. …”
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PyBootNet: a python package for bootstrapping and network construction by Shayan R. Akhavan, Scott T. Kelley

“…Background Network analysis has emerged as a tool for investigating interactions among species in a community, interactions among genes or proteins within cells, or interactions across different types of data (e.g., genes and metabolites). …”
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Evaluation of Recombinant Antibody Production Efficiency in CHO Cells with Sleeping Beauty Transposon Vector System by Pelin Kolçak Yaşlı, Seda Kulabaş, Evren Doruk Engin

“…Transposon systems can be utilized to overcome the limitations mentioned in the efficient production of commercially significant recombinant proteins. This study aims to demonstrate the differences in production potential and selection periods by using a specially designed vector system for random genome integration in CHODG44 DHFR -/- cells and the Sleeping Beauty (SB) transposon system. …”
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The Effect of PT Link and Waterbath Antigenic Retrieval Procedures On The Expression of Common Receptors In Breast Cancer Cases by Ahmed Abdelbadie, Elsadig Ahmed Adam, Manar Abdelrahman

“…Background: Antigen retrieval (AR) techniques play a major role in determining the quality and functional state of tissue proteins recovered from formalin fixed paraffin embedded blocks (FFPEB). …”
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Exploring Unique Extracellular Vesicles Associated Signatures: Prognostic Insights, Immune Microenvironment Dynamics, and Therapeutic Responses in Pancreatic Adenocarcinoma by Kai Nan, Ming Zhang, Zilong Geng, Yuankai Zhang, Lin Liu, Zhi Yang, Peng Xu

“…Extracellular vesicles play an important role in the progression of pancreatic adenocarcinoma (PAAD) through the transfer of proteins, mRNAs, and long noncoding RNAs (lncRNAs). …”
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The pathogenesis of COVID-19: Hypercoagulation and D-dimer in thrombotic complications by Leonid DUBEY, Halyna LYTVYN, Olha DOROSH, Nataliya DUBEY, Olena KOZLOVA, Michal PRUC, Nina KUBIKOWSKA, Lukasz SZARPAK, Kavita BATRA, Francesco CHIRICO, Gabriella NUCERA, Svitlana DOAN, Uljana SHEVTSIV

“…Plasmin is a key player in fibrinolysis and is involved in the cleavage of many viral envelope proteins, including SARS-CoV. Due to this function penetration of viruses into the host cell occurs. …”
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Prophylactic Role of Averrhoa carambola (Star Fruit) Extract against Chemically Induced Hepatocellular Carcinoma in Swiss Albino Mice by Ritu Singh, Jyoti Sharma, P. K. Goyal

“…Further, ACE treatment brings out a significant reduction in lipid peroxidation (P<0.001) along with an elevation in the activities of enzymatic antioxidants (superoxide dismutase, P<0.001, and catalase, P<0.001), nonenzymatic antioxidant (reduced glutathione, P<0.001), and total proteins (P<0.001) when compared to the carcinogen treated control. …”
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Advances in therapies using mesenchymal stem cells and their exosomes for treatment of peripheral nerve injury: state of the art and future perspectives by Fatima Aldali, Chunchu Deng, Mingbo Nie, Hong Chen

“…The latter are nano-sized extracellular vesicles containing bioactive molecules such as proteins, microRNA, and messenger RNA derived from parent mesenchymal stem cells. …”
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Blood-Brain Barrier Abnormalities Caused by HIV-1 gp120: Mechanistic and Therapeutic Implications by Jean-Pierre Louboutin, David S. Strayer

“…Gp120 reduced laminin and tight junction proteins. Reactive oxygen species (ROS) activate MMPs. …”
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Effects of Single-Nucleotide Polymorphisms in Cytokine, Toll-Like Receptor, and Progesterone Receptor Genes on Risk of Miscarriage by Anastasiia Razdaibiedina, Mykhaylo Khobzey, Victoria Tkachenko, Iryna Vorobiova

“…A delicate, stage-specific equilibrium of these proteins is required for successful pregnancy outcome. …”
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Optimization and Characterization of Silver Nanoparticle by Endophytic Fungi Penicillium sp. Isolated from Curcuma longa (Turmeric) and Application Studies against MDR E. coli and... by Dattu Singh, Vandana Rathod, Shivaraj Ninganagouda, Jyothi Hiremath, Ashish Kumar Singh, Jasmine Mathew

“…Further TEM revealed the formation of spherical, well-dispersed nanoparticles with size ranging between 25 and 30 nm and FTIR shows the bands at 1644 and 1538 cm−1 corresponding to the binding vibrations of amide I and II bands of proteins, respectively. Antibacterial activity against MDR E. coli and S. aureus showed good results showing maximum zone of inhibition of 17 mm and 16 mm, respectively, at 80 µL of AgNps.…”
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Mechanisms of transcriptional regulation of ecdysone response by M. Yu. Mazina, N. E. Vorobyeva

“…The description of the molecular mechanism of this process, in particular, the role of individual proteins in it, as well as structural interactions between various regulatory elements is a matter of the future. …”
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Symbiotic Root-Endophytic Soil Microbes Improve Crop Productivity and Provide Environmental Benefits by Gary E. Harman, Norman Uphoff

“…For example, all induce gene expression that produces proteins which detoxify reactive oxygen species (ROS). …”
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Autophagy: A New Avenue and Biochemical Mechanisms to Mitigate the Climate Change by Muhammad Abubakkar Azmat, Malaika Zaheer, Muhammad Shaban, Saman Arshad, Muhammad Hasan, Alyan Ashraf, Muhammad Naeem, Aftab Ahmad, Nayla Munawar

“…., old or damaged organelles, aggregates, and inactive or misfolded proteins. In optimal conditions, autophagy in plants ensures cellular homeostasis, proper plant growth, and fitness. …”
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Exploring the anticancer potential of Hewittia malabarica through phytochemical analysis and molecular docking study by Shiji Thozhukkad Moosaripparambil, Kannan Vadakkadath Meethal

“…When these compounds were docked on to Bax, Caspase-3 Caspase-9 and Cox-2, the proteins integral to the mitochondrial apoptotic pathway, using PyRX software, the docking score was in the range from − 4 to -6.9 kcal/mol. …”
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Transcriptional regulation by CHIP/LDB complexes. by Revital Bronstein, Liron Levkovitz, Nir Yosef, Michaela Yanku, Eytan Ruppin, Roded Sharan, Heiner Westphal, Brian Oliver, Daniel Segal

“…To date only few CHIP/LDB complexes target genes have been identified, and possible tissue-dependent crosstalk between these complexes has not been rigorously explored. SSDP proteins protect CHIP/LDB complexes from proteasome dependent degradation and are rate-limiting cofactors for these complexes. …”
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Diagnostic Test to Identify Parkinson’s Disease from the Blood Sera of Chinese Population: A Cross-Sectional Study by Guangan Tong, Pingping Zhang, Wenbin Hu, Kun Zhang, Xianwen Chen

“…Parkinson’s disease (PD) is a neurodegenerative disease, a hallmark by the formation of misfolded and aggregated α-synuclein proteins. The expression of potential microRNA (miRNA) candidates isolated from serum and cerebrospinal fluid (CSF) exosomes of PD patients was assessed for their diagnostic value and their potential role as biomarkers for PD was explored. …”
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Inotodiol induces hepatocellular carcinoma apoptosis by activation of MAPK/ERK pathway. by Yushuang Xing, Di Jia, Xinping Zhu, Jialu Yang, Zhipeng Gao, Nana Meng, Haohao Xu, Mengxiao Wang, Shijun Chang, Mingqian Zhao, Shanbo Zhang, Zichen Mu, Qiang Tang, Weiming Zhao

“…Meanwhile, western blotting was utilized to detect proteins associated with apoptosis, cell cycle and MAPK/ERK pathway. …”
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