A novel two-component system contributing the catabolism of c-di-GMP influences virulence in Aeromonas veronii by Chaolun Liu, Jia Shao, Xiang Ma, Yanqiong Tang, Juanjuan Li, Hong Li, Xue Chi, Zhu Liu

“…These effects might be elucidated by the upregulated inflammation-associated proteins in ΔarrS. Moreover, the exonuclease RecB was also up-regulated in ΔarrS.DiscussionWe elucidated the regulatory mechanism of ArrS/ArrR on intracellular c-di-GMP levels and its impact on the virulence in Aeromonas veronii, and discussed the intricate relationship between c-di-GMP metabolism and arginine metabolism.…”
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Evaluation of the Antimicrobial Effect of the Extracts of the Pods of Piliostigma thonningii (Schumach.) Milne-Redh. (Fabaceae) by Memory Makosa, Simbarashe Sithole, Stanley Mukanganyama

“…The ethanol extracts caused significant leakage of proteins in these microorganisms. In conclusion, the pods of P. thonningii contain phytochemicals with antimicrobial properties. …”
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Transient activation of YAP/TAZ confers resistance to morusin-induced apoptosis by Hoyeon Lee, Sang Woo Cho, Hyo Sun Cha, Kun Tae, Cheol Yong Choi

“…Abstract Background The Hippo signaling pathway involves a kinase cascade that controls phosphorylation of the effector proteins YAP and TAZ, leading to regulation of cell growth, tissue homeostasis, and apoptosis. …”
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Metabolic and hematological disruptions induced by Diphenyl Diselenide in male wistar rats by Joseph A. Olagunju, Gabriel O. Ajayi, Babatunde A. Murtala, Adejuwan A. Adeneye

“…Diphenyldiselenide (DPDS), a potent antioxidant and enzyme inhibitor, exerts cellular toxicity mainly through interaction with thiol group of proteins. This study evaluates its toxicity on glycolysis and gluconeogenesis as well as on some hematological parameters in male Wistar rats. …”
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Primary metabolomics and transcriptomic techniques were used to explore the regulatory mechanisms that may influence the flavor characteristics of fresh Corylus heterophylla × Cory... by Minmin Lu, Tiantian Xie, Yaru Wang, Jieyan Yang, Yan Bai, Shuang Gao, Xiaofan Wu, Xiuqing Yang

“…CS and OGDH were deemed as the genes involved in the citric acid cycle, which was a central metabolic pathway that generated energy through the oxidation of carbohydrates, fats and proteins in hazelnuts. The genes trpD, ALDO, PK-1, PK-2, ilvH, argE-1, argE-4, argE-5, argD, PDAH, GLTI were regarded as involved in the biosynthesis of various amino acids like tryptophan, valine, alanine, and arginine. …”
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New Information of the Anatomy and Phytochemical Screening of Pentaclethra macroloba (Willd.) Kuntze (Caesalpinioideae-Leguminosae) Seeds by Zelina Ataíde Correia, Ely Simone Cajueiro Gurgel, Olivia Ribeiro, Ana Cristina de Andrade Aguiar Dias, Ravendra Kumar, Luis Adriano Santos do Nascimento, Eloisa Helena de Aguiar Andrade, Mozaniel Santana de Oliveira

“…The main metabolic classes are lipids, phenolic compounds, carbohydrates, proteins, and alkaloids. The main fatty acids found in P. macroloba oil are oleic, behenic, lignoceric, and linoleic. …”
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A Sensitive Fluorescent Immunoassay for Prostate Specific Antigen Detection Based on Signal Amplify Strategy of Horseradish Peroxidase and Silicon Dioxide Nanospheres by Lihua Li, Wenzhi Zhang, Yan Wei, Lizhen Yu, Dexiang Feng

“…., which can be widely used in the selective detection of a variety of targets, from DNA to proteins and small molecules. Such fluorescent immunoassays should be feasible for the fields of molecular diagnosis and other life science fields in the future.…”
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Dual Control of Host Actin Polymerization by a Legionella Effector Pair by M. Pillon, C. Michard, N. Baïlo, J. Bougnon, K. Picq, O. Dubois, C. Andrea, L. Attaiech, V. Daubin, S. Jarraud, E. Kay, P. Doublet

“…Legionella pneumophila virulence relies on the injection of the largest known arsenal of bacterial proteins, over 300 Dot/Icm type 4 secretion system effectors, into the host cytosol. …”
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Therapeutic Potential of Synthetic Human β-Defensin 1 Short Motif Pep-B on Lipopolysaccharide-Stimulated Human Dental Pulp Stem Cells by Jue Shi, Zihe Hu, Yanyan Zhou, Minghao Zuo, Haiyan Wu, Wenjing Jin, Zhijian Xie

“…Pep-B also enhanced the expression of the osteo-/odontogenic genes and proteins, alkaline phosphatase activity, and nodule mineralization in LPS-stimulated hDPSCs. …”
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Diabetes-Resistant NOR Mice Are More Severely Affected by Streptozotocin Compared to the Diabetes-Prone NOD Mice: Correlations with Liver and Kidney GLUT2 Expressions by S. Kahraman, C. Aydin, G. O. Elpek, E. Dirice, A. D. Sanlioglu

“…STZ is taken inside cells via GLUT2 transmembrane carrier proteins, the major glucose transporter isoforms in pancreatic beta cells, liver, kidneys, and the small intestine. …”
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MARCHF8-mediated ubiquitination via TGFBI regulates NF-κB dependent inflammatory responses and ECM degradation in intervertebral disc degeneration. by Xingpeng Zhang, Guang Li, Fang Tan, Tao Yu, Chengping Xu, Kai Li, Feng Zhang, Meiyan Zhang, Jian Wang

“…<h4>Objective</h4>Identify key modules associated with IDD and understand the impact of TGFBI on nucleus pulposus (NP) cell behavior, extracellular matrix (ECM)-related proteins, and the Nuclear Factor kappa-light-chain-enhancer of Activated B cells (NF-κB) signaling pathway.…”
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Nanorobots with Hybrid Biomembranes for Simultaneous Degradation of Toxic Microorganism by Mohamad Reda A. Refaai, M. N. Manjunatha, S. Radjarejesri, B. Ramesh, Ram Subbiah, Nahom Adugna

“…These hybrid cell walls consist of a variety of structural proteins involved in living organism RBCs and PLs, which provide nanorobots with either a quantity of the appealing biological functionality, with bonding and adhesion to the PL-adhering pathogenic organisms (for example, staphylococcus bacteria) but also neutralization of the pore-forming toxins (e.g., toxin). …”
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A bird’s-eye view of the biological mechanism and machine learning prediction approaches for cell-penetrating peptides by Maduravani Ramasundaram, Honglae Sohn, Thirumurthy Madhavan

“…Cell-penetrating peptides (CPPs) are highly effective at passing through eukaryotic membranes with various cargo molecules, like drugs, proteins, nucleic acids, and nanoparticles, without causing significant harm. …”
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TRIM25: A Global Player of Cell Death Pathways and Promising Target of Tumor-Sensitizing Therapies by Wolfgang Eberhardt, Usman Nasrullah, Josef Pfeilschifter

“…., acquired by random mutations, cancer cells typically escape from certain treatments (“acquired resistance”) by a large variety of means, including suppression of apoptosis and other cell death pathways via upregulation of anti-apoptotic factors or through inhibition of tumor-suppressive proteins. Therefore, ideally, the tumor-cell-restricted induction of apoptosis is still considered a promising avenue for the development of novel, tumor (re)sensitizing therapies. …”
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Potential Role of African Fermented Indigenous Vegetables in Maternal and Child Nutrition in Sub-Saharan Africa by Marie Lys Irakoze, Eliud N. Wafula, Eddy Owaga

“…Apart from extending shelf life and improving food organoleptic properties, fermentation of African indigenous vegetables (AIVs) is known to improve food nutritional values such as proteins, minerals, vitamins, and other beneficial phytochemicals. …”
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Wild Edible Plant Nutritional Contribution and Consumer Perception in Ethiopia by Haile Tesfaye Duguma

“…Wild edible plants have high nutritional content, including proteins, vitamin B2, and vitamin C, which can be used as alternatives to conventional plant-based human diets. …”
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VETOZIM MULTI - AN INNOVATIVE SOLUTION FOR THE POULTRY INDUSTRY by O. Khodakivskyi, Ye. Baranovskyi

“…The presence of thermostable enzymes in the composition of the Vetozym Multi preparation allows it to be used in the production of compound feeds with advanced heat treatment at a conditioning and granulation temperature of up to +90 °C, which will contribute to a more complete breakdown and assimilation of raw material components, in particular carbohydrates, proteins and fiber. Calculation of economic indicators shows that the drug Vetozym Multi not only provides balanced nutrition for poultry, but also allows you to reduce the cost of feed due to more efficient use of less expensive components.…”
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A review on egg waste-based adsorbents for the removal of organic and inorganic contaminants from aqueous solution by Alusani Manyatshe, Linda Lunga Sibali

“…Characterisation techniques showed that the raw eggshells and membranes consisted mainly of calcium carbonate (CaCO3) and proteins (amine and carboxylic groups). Most studies have focused on using adsorbents based on eggshells to remove various contaminants, including dyes, phenols, aromatic carbons, anions, metals, and pharmaceuticals. …”
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Effect of Uncaria rhynchophylla against Thioacetamide-Induced Acute Liver Injury in Rat by Mi-Rae Shin, Min Ju Kim, Jin A Lee, Seong-Soo Roh

“…Moreover, expressions of inflammation and collagen-related proteins were measured by the Western blot analysis. …”
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CLARITY and Light-Sheet microscopy sample preparation in application to human cerebral organoids by T. A. Shnaider, I. E. Pristyazhnyuk

“…This method is based on a special sample preparation, during which lipids are removed from cells and replaced with hydrogel compounds such as acrylamide, while proteins and nucleic acids remain intact. CLARITY provides researchers with a unique opportunity to study three-dimensional biological structures while preserving their internal organization, including whole animals or embryos, individual organs and artificially grown organoids, in particular cerebral organoids. …”
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