JK-1, a useful erythroleukemic cell line model to study a controlled erythroid differentiation from progenitors to terminal erythropoiesis by Sylvain Metral, Sandrine Genetet, Benoît Gamain, Isabelle Mouro-Chanteloup

“…Enlarged phenotyping was carried out for the earlier phase, and expression kinetics of membrane proteins such as RhAG, RhD/CE, CD47, DARC and CD44 were performed on each stage of the terminal phase. …”
Get full text

The Phytochemical Screening and Antioxidants Potential of Schoenoplectus triqueter L. Palla by Amir Hassan, Zakaria Akmal, Nawaz Khan

“…Important types of phytochemicals found in this species are alkaloids, proteins, amino acids, flavonoids, phenols, terpenoids, tannins, saponins, and carbohydrates. …”
Get full text

Nerve root magnetic stimulation regulates the synaptic plasticity of injured spinal cord by ascending sensory pathway by Ya Zheng, Lingyun Cao, Dan Zhao, Qi Yang, Chunya Gu, Yeran Mao, Guangyue Zhu, Yulian Zhu, Jing Zhao, Dongsheng Xu

“…Furthermore, nerve root magnetic stimulation decreased the levels of acetylcholine, norepinephrine, and dopamine, and increased the expression of synaptic plasticity-related mRNA and proteins PSD95, GAP43, and Synapsin II. Taken together, these results showed that nerve root magnetic stimulation alleviated neuronal damage in the injured spinal cord, regulated synaptic plasticity, and suppressed inflammatory responses. …”
Get full text

Amelioration of Nephrotoxicity in Mice Induced by Antituberculosis Drugs Using Ensete ventricosum (Welw.) Cheesman Corm Extract by Abebe Dukessa Dubiwak, Urge Gerema, Daba Abdisa, Ebsa Tofik, Wondu Reta

“…Serum levels of creatinine, blood urea nitrogen (BUN), and uric acid of the Group-II mice were significantly (P<0.01) elevated, and serum levels of total proteins and albumin of Group-II mice were significantly (P<0.01) decreased as compared to Group-I. …”
Get full text

Mesenchymal Stem Cell–Sourced Exosomes as Potentially Novel Remedies for Severe Dry Eye Disease by Carl Randall Harrell, Valentin Djonov, Ana Volarevic, Aleksandar Arsenijevic, Vladislav Volarevic

“…MSC-Exos contain a variety of bioactive proteins (growth factors, immunoregulatory molecules, cytokines, and chemokines) lipids, and microRNAs (miRNAs) which affect viability, proliferation, phenotype, and function of eye-infiltrated immune cells. …”
Get full text

Insights into the mechanism of antiproliferative effects of primaquine-cinnamic acid conjugates on MCF-7 cells by Mabeta Peace, Pavić Kristina, Zorc Branka

“…Further analysis to determine the effects of test compounds on caspase activity and on the levels of apoptosis proteins were undertaken using the enzyme-linked immunosorbent assay (ELISA). …”
Get full text

Anthropometric but not motor characteristics of young volleyball players were improved after a one-week-long intense training sports camp by Robert Podstawski, Joanna M. Bukowska, Krzysztof Borysławski, Elżbieta Biernat, Daria Grodź, Ferenc Ihasz, Jacek Wąsik

“…An increase was noted in total body water (Δ of 1.0 L, p = 0.002), proteins (Δ of 0.33 kg, p = 0.001), minerals (Δ of 0.12 kg, p = 0.003), fat-free mass (Δ of 1.46 kg, p = 0.001), and skeletal muscle mass (Δ of 0.9 kg, p = 0.001). …”
Get full text

Replication timing in Drosophila and its peculiarities in polytene chromosomes by T. D. Kolesnikova, O. V. Antonenko, I. V. Makunin

“…The speed of replication forks in D. melanogaster polytene chromosomes is affected by SUUR and Rif1 proteins. It is not known yet how universal the mechanisms associated with these factors are, but their study is very promising.…”
Get full text

N-Acetylcysteine Decreases Myocardial Content of Inflammatory Mediators Preventing the Development of Inflammation State and Oxidative Stress in Rats Subjected to a High-Fat Diet by Klaudia Sztolsztener, Wiktor Bzdęga, Katarzyna Hodun, Adrian Chabowski

“…The Gas-Liquid Chromatography (GLC) method was used to quantify the plasma and myocardial AA levels in the selected lipid fraction. The expression of proteins included in the inflammation pathway was measured by the Western blot technique. …”
Get full text

Achyranthes bidentata Polysaccharide along with Anti-IL-5 Antibody Inhibits Allergic Lung Inflammation and Airway Hyperresponsiveness Mice Induced by House Dust Mites by Jian Sun, Shiwei Sheng, Gang Zhao

“…Besides this, ABPS is reported that can induce apoptosis of eosinophils by upregulating the expression of proteins involved in apoptosis. In this study, we constructed chronic allergic asthma mice model induced by house dust mites (HDM) with airway hyperresponsiveness (AHR) and found that anti-IL-5 mAb and ABPS treatment can both decrease inflammatory cells infiltration especially eosinophils and decrease the level of serum IgE and HDM-specific IgG1. …”
Get full text

Microbial Control in the Processing of Low-Temperature Meat Products: Non-Thermal Sterilization and Natural Antimicrobials by Xiaoyang Zhang, Feng Na, Min Zhang, Wei Yang

“…Low-temperature meat products refer to those that are processed at lower temperatures. Meat, rich in proteins and other nutrients, is highly susceptible to microbial contamination, leading to spoilage, particularly when processed at lower temperatures that increase storage and transportation requirements. …”
Get full text

The role of the NOTCH1 signaling pathway in the maintenance of mesenchymal stem cell stemness and chondrocyte differentiation and its potential in the treatment of osteoarthritis by Fuming Wu, Haiquan Yu

“…Under conditions of endoplasmic reticulum stress, NOTCH1 expression helped reduce the expression of stress-related proteins, maintain chondrocyte homeostasis, and inhibit apoptosis. …”
Get full text

BIOSYNTHESIS OF NANOPARTICLES FROM PLANT EXTRACTS AND THEIR APPLICATIONS IN MEDICAL TREATMENTS AND DRUG DELIVERY: A REVIEW by N. A. Jdayea, E. E. Al-Abodi

“…Phenolic amino acids, flavonoids, terpenoids, and proteins are examples of reducing and oxidizing agents. …”
Get full text

Immune Cell Profiling Reveals a Common Pattern in Premetastatic Niche Formation Across Various Cancer Types by Shigeaki Sugiyama, Kanae Yumimoto, Keiichi I. Nakayama

“…Discussion Validation of our findings in humans will require data on the presence or absence of micrometastases in patients and the accumulation of comprehensive and temporal information on immune cells. In addition, blood proteins, extracellular vesicles, DNA, RNA, or metabolites may be useful for more accurate prediction. …”
Get full text

Therapeutic Response of Alopecia Areata-Associated Nail Changes to Baricitinib by Ashley Wittmer, Katherine De Jong, Lauren Bolish, Lindsey Finklea

“…Baricitinib is an immunomodulatory drug that acts as a selective and reversible inhibitor of JAK proteins and is indicated for adult patients with moderate to severe rheumatoid arthritis who have not responded to other disease-modifying antirheumatic drugs. …”
Get full text

Structure and evolution of metapolycentromeres by E. O. Grishko, P. M. Borodin

“…Addressing the “centromere paradox” – the rapid evolution of centromeric DNA and proteins despite their conserved cellular function – we explore the centromere drive hypothesis as a plausible explanation for the dynamic evolution of centromeres in general, and in particular the emergence of metapolycentromeres and holocentromeres. …”
Get full text

An Overview of the Nutritional Requirements of Honey Bees (<i>Apis mellifera</i> Linnaeus, 1758) by Leticia S. Ansaloni, Janja Kristl, Caio E. C. Domingues, Aleš Gregorc

“…An adequate diet includes the consumption of sufficient amounts of proteins, carbohydrates, lipids, amino acids, vitamins, minerals, water, and essential sterols, and a diet based on multi-floral pollen is desirable. …”
Get full text

Foreword—Breaking barriers in chemical biology: the innovative tour de force of the ChemBio GDR by Lopez, Marie, Mileo, Elisabetta, Defrancq, Eric, Delmas, Agnès,  Vauzeilles, Boris, Guianvarc’h, Dominique, Biot, Christophe

Get full text

Intracellular Membrane Contact Sites in Skeletal Muscle Cells by Matteo Serano, Stefano Perni, Enrico Pierantozzi, Annunziatina Laurino, Vincenzo Sorrentino, Daniela Rossi

“…Triads are skeletal muscle-specific contact sites where Ca²⁺ channels and regulatory proteins assemble to form the so-called calcium release complex. …”
Get full text

LEAF HAIRINESS IN POTATO Solanum tuberosum: MORPHOLOGY, FUNCTION AND METHODS OF ANALYSIS by A. V. Doroshkov, D. A. Afonnikov

“…These are genes involved in the formation of a complex of MYB-bHLH-WD40, which controls the differentiation and development of trichomes in plants. The proteins of this complex in potatoes are primarily studied in connection with the regulation of the biosynthesis of anthocyanins. …”
Get full text