Cytokine-armed oncolytic herpes simplex viruses: a game-changer in cancer immunotherapy? by Howard L Kaufman, Hongbin Wang, Dipongkor Saha, Samuel D Rabkin, Mia Borlongan, Uyen Le, Hans J Nauwynck

“…Cytokines are small proteins that regulate the growth and functional activity of immune cells, and several have been approved for cancer therapy. …”
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Membrane Fouling and Chemical Cleaning in Three Full-Scale Reverse Osmosis Plants Producing Demineralized Water by Florian Beyer, Judita Laurinonyte, Arie Zwijnenburg, Alfons J. M. Stams, Caroline M. Plugge

“…Fouling layer measurements included total organic carbon (TOC), adenosine triphosphate, polysaccharides, proteins, and heterotrophic plate counts. In all locations, membrane and spacer fouling was (bio)organic. …”
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Genome Structure of Bacillus cereus tsu1 and Genes Involved in Cellulose Degradation and Poly-3-Hydroxybutyrate Synthesis by Hui Li, Suping Zhou, Terrance Johnson, Koen Vercruysse, Ouyang Lizhi, Parthasarathy Ranganathan, Nsoki Phambu, Alexander J. Ropelewski, Theodore W. Thannhauser

“…The five PHB genes in tsu1 (phaA, phaB, phaR, phaC, and phaP) were cloned and expressed with TOPO cloning, and the recombinant proteins were validated using peptide mapping of in-gel trypsin digestion followed by mass spectrometry analysis. …”
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RNA Polymerase RPOTp is Involved in C‐to‐U RNA Editing at Multiple Sites in Arabidopsis Chloroplasts by Nadia Ahmed Ali, Wenjian Song, Yayi Zhang, Jiani Xing, Kexing Su, Xingxing Sun, Yujia Sun, Yizhou Jiang, Dianxing Wu, Xiaobo Zhao

“…It is further shown that RPOTp participates in RNA editing by influencing the dimerization of MORF proteins. The defect in RPOTp impairs the expression of most chloroplast genes, indicating an indispensable role for RPOTp in chloroplast gene expression. …”
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Quails of Stavropol Region: Autumn Food Habits by Anatoly P. Kaledin, Lyubov V. Malovichko, Alexander G. Rezanov, Lyudmila S. Drozdova, Andiya T. Serikbayeva

“…Quail farming is quite popular because quail meat is low in calories and possesses a number of beneficial properties, e.g., it is rich in proteins, contains little fat and virtually no carbohydrates, etc. …”
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Biofertilizing Effect of Soil Cyanobacterium <i>Anabaena cylindrica</i>–Based Formulations on Wheat Growth, Physiology, and Soil Fertility by Zineb Hakkoum, Farah Minaoui, Amer Chabili, Mountasser Douma, Khadija Mouhri, Mohammed Loudiki

“…The wheat growth–promoting effect was attributed to the intracellular or released bioactive compounds of <i>A. cylindrica</i>, such as polysaccharides, proteins, indole acetic acid phytohormone, nitrogen, phosphorus, and potassium. …”
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Targeting the epigenome with advanced delivery strategies for epigenetic modulators by Sonia Guha, Yogeswaran Jagadeesan, Murali Monohar Pandey, Anupama Mittal, Deepak Chitkara

“…Abstract Epigenetics mechanisms play a significant role in human diseases by altering DNA methylation status, chromatin structure, and/or modifying histone proteins. By modulating the epigenetic status, the expression of genes can be regulated without any change in the DNA sequence itself. …”
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Cultivation and molecular characterization of complete genome sequences of M. pneumoniae isolated in Russia by Matsvay A.D., Bezrukov V.M., Nikolaeva P.A., Stetsenko I.F., Nurmukanova V.A., Dikaya G.S., Gordukova M.A., Galeeva E.V., Shipulin G.A.

“…Utilizing all genomic sequences of M. pneumoniae available in public databases, we conducted a phylogenetic analysis as well as a comparative analysis of clinically significant genes, revealing previously undescribed mutations in cytoadherence proteins. Conclusions. In this study, we characterized the first full genome sequences of M. pneumoniae isolated in the Russian Federation, as well as provided detailed methods for cultivating the pathogen and the data processing process, which can be used to further expand the amount of available data on the genetic structure of the pathogen.…”
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Space and Time Resolved Detection of Platelet Activation and von Willebrand Factor Conformational Changes in Deep Suspensions by Jacopo Biasetti, Kaushik Sampath, Angel Cortez, Alaleh Azhir, Assaf A. Gilad, Thomas S. Kickler, Tobias Obser, Zaverio M. Ruggeri, Joseph Katz

“…Tracking cells and proteins’ phenotypic changes in deep suspensions is critical for the direct imaging of blood-related phenomena in in vitro replica of cardiovascular systems and blood-handling devices. …”
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Thrombin Promotes Matrix Metalloproteinase-13 Expression through the PKCδ/c-Src/EGFR/PI3K/Akt/AP-1 Signaling Pathway in Human Chondrocytes by Chun-Yin Huang, Hsiu-Jung Lin, Hsin-Shui Chen, Shi-Yann Cheng, Horng-Chaung Hsu, Chih-Hsin Tang

“…Treatment with specific inhibitors for PKCδ, c-Src, EGFR, PI3K, Akt, or AP-1 or with the corresponding siRNAs against these signaling proteins also abolished the thrombin-mediated increase in MMP-13 production in chondrocytes. …”
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Network pharmacology and experimental verification reveal the mechanism of Qingfei Tongluo mixture in treating pulmonary fibrosis by Ying Zhou, Wenlong Wang, Wanping Zhu, Tingting Cai, Nannan Wang, Xia Liu, Wenmin Wang, Kequn Chai

“…Animal experiments demonstrated that QTm improved alveolar structure, reduced interstitial lesions, and enhanced lung function while decreasing hydroxyproline content and the expression of FTO and TGF-β1 proteins. Conclusions: QTm may inhibit PF progression by suppressing FTO/TGF-β1 expression, thereby improving lung function. …”
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Restorative effects of camellia oil on the skin-barrier function in a model of DNCB-induced atopic dermatitis by Shicheng Jiao, Lijun Deng, Mu Niu, Jie Yang

“… This study aimed to evaluate the therapeutic efficacy of camellia oil on 2,4-dinitrochlorobenzene (DNCB)-induced atopic dermatitis (AD) in mice, as well as its effect on the expression of skin-barrier-related proteins. A mouse model of AD was created via topical application of DNCB; subsequently, the animals were randomly divided into four groups: the blank control (Control), model (Model), moisturizing cream (Moisturizer), and camellia oil (Camellia) groups. …”
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The Effect of Mechanical Ventilation on TASK-1 Expression in the Brain in a Rat Model by Buqi Na, Hong Zhang, Guangfa Wang, Li Dai, Guoguang Xia

“…We measured lung histology and plasma and brain levels of proteins (IL-6, TNF-α, and S-100B) and determined TASK-1 levels in rat brainstems as a marker of respiratory centre activity. …”
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High-resolution mass spectrometry measurement of N-terminal carbamylated hemoglobin as a potential marker for chronic diseases with elevated blood urea levels by Fangjun Chen, Priscilla S.-W. Yeung, Carolyn V. Wong, Ruben Y. Luo

“…Beyond CarHb, the use of other carbamylated proteins as clinical diagnostic and prognostic markers can be explored.…”
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Effectiveness of Fibers from “Cabernet Sauvignon” (Vitis vinifera) Pomace as Fining Agents for Red Wines by Mariona Gil, Rubén Del Barrio-Galán, Cristina Úbeda, Álvaro Peña-Neira

“…Recent findings have highlighted the potential of fibers from grape cell wall material to be fining agents for red wines as alternatives to animal-derived proteins. The affinity of those fibers for grape proanthocyanidins (also known as condensed tannins) seems to depend on the initial phenolic composition of the wines to be fined and on the applied dose of fibers. …”
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Macrophage-inherited exosome excise tumor immunosuppression to expedite immune-activated ferroptosis by Yan Liu, Junjie Liu, Qin Wang, Kun Zhang, Chunyan Zhu, Duo Wang, Guanhua Qiu, Xiaoqi Zhu, Chao Fang

“…The delivered RSL3 that serves as a common ferroptosis inducer can reduce the levels of ferroptosis hallmarkers (eg, glutathione and glutathione peroxidase 4), break the redox homeostasis to magnify oxidative stress accumulation, promote the expression of ferroptosis-related proteins, and induce robust ferroptosis of tumor cells, accompanied with which systematic immune response activation can bbe realized. …”
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Strong inhibitory effects of Desmodesmus sp. on Microcystis blooms: Potential as a biological control agent in aquaculture by Bo Yang, Yuhua Li, Zihan Wang, Zhiguang Yue, Junqi Wen, Xueqin Zhao, Hu Zhang, Xianfeng Wang, Xiufen Wang, Man Zhang

“…Furthermore, Desmodesmus sp. possessed a high content of proteins and polyunsaturated fatty acids, consequently providing additional value for fish in aquaculture. …”
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The impact of Ca2+ on the protective mechanisms of the photosystem under drought stress by Yanli Wei, Tongen Zhang, Tongtong Yao, Zihan Wang, Yanhui Che, Huihui Zhang

“…Transcriptomic analysis revealed a significant reduction in the expression of genes related to the PSI and PSII reaction centers, ATP synthesis, electron transport, and antenna proteins under drought stress. The application of calcium significantly alleviated the drought-induced downregulation of these genes. …”
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Genomic Variability among Field Isolates and Laboratory-Adapted Strains of Leptospira borgpetersenii Serovar Hardjo by Alejandro Llanes, Carlos Mario Restrepo, Pablo Riesgo-Ferreiro, Sreekumari Rajeev

“…Putative type-specific genes appear to encode proteins associated with functions that are critical for infection. …”
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Unraveling the Role of Ubiquitin-Conjugating Enzyme UBE2T in Tumorigenesis: A Comprehensive Review by Chang Gao, Yan-Jun Liu, Jing Yu, Ran Wang, Jin-Jin Shi, Ru-Yi Chen, Guan-Jun Yang, Jiong Chen

“…Ubiquitin-conjugating enzyme E2 T (UBE2T) is a crucial E2 enzyme in the ubiquitin-proteasome system (UPS), playing a significant role in the ubiquitination of proteins and influencing a wide range of cellular processes, including proliferation, differentiation, apoptosis, invasion, and metabolism. …”
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