Quantitation of α-Lactalbumin by Liquid Chromatography Tandem Mass Spectrometry in Medicinal Adjuvant Lactose by Rui Yan, Longmei Qu, Nan Luo, Yang Liu, Yu Liu, Li Li, Lijiang Chen

“…Lactose is a widely used pharmaceutical excipient, sometimes irreplaceable. Traces of residual proteins left during production of lactose are potential allergen to body. …”
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Anti-colon cancer activity of water-soluble polysaccharides extracted from Gloeostereum incarnatum via Wnt/β-catenin signaling pathway by Jiawei He, Anhui Yang, Xuyu Zhao, Yang Liu, Shuyan Liu, Di Wang

“…GIPS suppressed nuclear aggregation of β-catenin, affected the expression of WNT1 and related proteins, thereby regulated the activation of the Wnt signaling. …”
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Molecular cloning of EZH2 oncogene in chronic myeloid leukemia and therapeutic prospects by Juliana Costa Gaspar, Lucas Santos de Santana, Camila Menezes Freire de Souza, Marcos Montani Caseiro, Rosane Rezende de Souza Giuliani, Cleide Barbieri de Souza

“…Chronic myeloid leukemia (CML) is a myeloproliferative neoplasia, caused in 95 % of the cases by a cytogenetic abnormality characterized by the reciprocal translocation between chromosomes 9 and 22 t(9; 22) (q34; q11), resulting in Philadelphia chromosome (Ph).Considering that CML cure is only possible with a successful bone marrow transplantation and that there are resistance cases to the tyrosine kinase inhibitor Imatinib Mesylate, prescribed in first line drug treatment; it is important to know in detail the genes and proteins that are possibly altered in CML, favoring effective therapeutic strategies, optimized diagnosis and minimal residual disease detection. …”
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Engineered Bacillus subtilis WB600/ZD prevents Salmonella Infantis-induced intestinal inflammation and alters the colon microbiota in a mouse model by Wei Li, Xue Wang, Keyuan Chen, Yaohong Zhu, Guiyan Yang, Yipeng Jin, Jiufeng Wang

“…Infantis infection and increased expression of antioxidant and tight junction proteins, thus alleviating the severity of intestinal inflammation in both the jejunum and ileum (P < 0.01). …”
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Biomimetic mineralization of diatom exoskeleton for sustainable pH-sensitive colored chitosan/silica hybrid self-supported films by Sandra Castanié, Laurent Billon

“…It was found that chitosan (CS) biopolymer, a polysaccharide possessing numerous amine groups (–NH2) is capable of mimicking the action of the silaffins proteins of diatom frustule in the polycondensation process of the TetraEthoxyOrthoSilicate (TEOS) silica precursor to form a cohesive self-supported hybrid film under soft conditions in aqueous media. …”
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Glioblastoma drives protease-independent extracellular matrix invasion of microglia by Chia-Wen Chang, Ashwin Bale, Rohit Bhargava, Brendan A.C. Harley

“…We also identify a panel of soluble proteins that may contribute to microglia chemotaxis, such as TIMP-1 and CXCL12. …”
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Bioconversion of Airborne Methylamine by Immobilized Recombinant Amine Oxidase from the Thermotolerant Yeast Hansenula polymorpha by Sasi Sigawi, Marina Nisnevitch, Oksana Zakalska, Andriy Zakalskiy, Yeshayahu Nitzan, Mykhailo Gonchar

“…Aliphatic amines, including methylamine, are air-pollutants, due to their intensive use in industry and the natural degradation of proteins, amino acids, and other nitrogen-containing compounds in biological samples. …”
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TEEG Induced A549 Cell Autophagy by Regulating the PI3K/AKT/mTOR Signaling Pathway by Lu Shi, Yijun Tu, Yu Xia, Siqi Ye, Chaozhi Ma, Yanwen Liu, Pengtao You

“…Autophagy-associated proteins were examined by Western blot analysis. TEEG markedly inhibited A549 cell proliferation in a concentration-dependent manner. …”
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Activation of Human Neutrophils by the Anti-Inflammatory Mediator Esenbeckia leiocarpa Leads to Atypical Apoptosis by Rafael de Liz, Heros Horst, Moacir Geraldo Pizzolatti, Tânia Silvia Fröde, Denis Girard

“…CHE increased the degradation of the cytoskeletal proteins gelsolin and paxillin but, surprisingly, not of vimentin. …”
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Advanced Efficient Feature Selection Integrating Augmented Extreme Learning Machine and Particle Swarm Optimization for Predicting Nitrogen Use Efficiency and Yield in Corn by Josselin Bontemps, Isa Ebtehaj, Gabriel Deslauriers, Alain N. Rousseau, Hossein Bonakdari, Jacynthe Dessureault-Rompré

“…The results highlight that integrating soil health indicators such as enzyme activities (β-glucosidase [BG] and N-acetyl-β-D-glucosaminidase [NAG]) and soil proteins into nitrogen management models improves prediction accuracy, leading to enhanced productivity and environmental sustainability. …”
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Exploring the Structural Diversity and Biotechnological Potential of the Rhodophyte Phycolectome by Éllen F. Rodrigues, Flavia Alves Verza, Felipe Garcia Nishimura, Renê Oliveira Beleboni, Cedric Hermans, Kaat Janssens, Maarten Lieven De Mol, Paco Hulpiau, Mozart Marins

“…Lectins are non-covalent glycan-binding proteins found in all living organisms, binding specifically to carbohydrates through glycan-binding domains. …”
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Amphiphiles Self-Assembly: Basic Concepts and Future Perspectives of Supramolecular Approaches by Domenico Lombardo, Mikhail A. Kiselev, Salvatore Magazù, Pietro Calandra

“…Self-assembly processes of amphiphiles have been widely used to mimic biological systems, such as assembly of lipids and proteins, while their integrated actions allow the performance of highly specific cellular functions which has paved a way for bottom-up bionanotechnology. …”
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Junshanyinzhen tea extract prevents obesity by regulating gut microbiota and metabolic endotoxemia in high-fat diet fed rats by Jian Ouyang, Xiuping Li, Changwei Liu, Danmin Lu, Jie Ouyang, Fang Zhou, Qi Liu, Jianan Huang, Zhonghua Liu

“…In addition, JSTE increased the expression of intestinal tight junction proteins (P &lt; 0.05), relieved metabolic endotoxemia (P &lt; 0.05) and chronic low- grade inflammation in HFD rats. …”
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New Insights in the Pathogenesis of HPV Infection and the Associated Carcinogenic Processes: The Role of Chronic Inflammation and Oxidative Stress by Simona Roxana Georgescu, Cristina Iulia Mitran, Madalina Irina Mitran, Constantin Caruntu, Maria Isabela Sarbu, Clara Matei, Ilinca Nicolae, Sandra Milena Tocut, Mircea Ioan Popa, Mircea Tampa

“…Reactive oxygen species exert a harmful effect on proteins, lipids, and nucleic acids. Viral oncogenes E5, E6, and E7 are involved in the development of chronic inflammation through various mechanisms. …”
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Cloned airway basal progenitor cells to repair fibrotic lung through re-epithelialization by Yu Zhao, Yueqing Zhou, Weipan Zhang, Mingzhe Liu, Jun Duan, Xiaopeng Zhang, Qiwang Ma, Yujia Wang, Yuzhen Zhang, Zhongliang Guo, Ting Zhang, Wei Zuo

“…Mechanistically, the engrafted human progenitor cells do not function by differentiating into mature alveolar cells in mouse lung; instead, they differentiate into saccular cells expressing multiple tight junction proteins such as CLDN4, which help the lung to re-establish epithelial barriers. …”
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Molecular Mechanism of Local Drug Delivery with Paclitaxel-Eluting Membranes in Biliary and Pancreatic Cancer: New Application for an Old Drug by Sookhee Bang, Sung Ill Jang, Su Yeon Lee, Yi-Yong Baek, Jieun Yun, Soo Jin Oh, Chang Woo Lee, Eun Ae Jo, Kun Na, Sugeun Yang, Don Haeng Lee, Dong Ki Lee

“…Moreover, implantation of the PEM inhibited tumor-stromal interaction-related expression of proteins such as CD44, SPARC, matrix metalloproteinase-2, and vimentin. …”
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Human Amniotic Fluid Mesenchymal Stem Cells from Second- and Third-Trimester Amniocentesis: Differentiation Potential, Molecular Signature, and Proteome Analysis by Jurate Savickiene, Grazina Treigyte, Sandra Baronaite, Giedre Valiuliene, Algirdas Kaupinis, Mindaugas Valius, Audrone Arlauskiene, Ruta Navakauskiene

“…The analysis of the functional and expression patterns of 250 high abundance proteins selected from more than 1400 demonstrated the similar proteome of cultured and differentiated AF-MSCs but the unique changes in their expression profile during cell differentiation that may help the identification of key markers in differentiated cells. …”
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Exosomal non-coding RNAs in the regulation of bone metabolism homeostasis: Molecular mechanism and therapeutic potential by Chengxiong Huang, Yu Xiao, Liming Qing, Juyu Tang, Panfeng Wu

“…Exos are rich in a variety of bioactive substances, such as non-coding RNAs, nucleic acids, proteins and lipids. In view of the structure of Exos, it can protect the biologically active molecules can be smoothly delivered to the target cells and involved in the regulation of cell function. …”
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Analysis of Biomolecular Changes in HeLa Cervical Cancer Cell Line Induced by Interaction with [Pd(dach)Cl₂] by Vanja Ralić, Maja D. Nešić, Tanja Dučić, Milutin Stepić, Lela Korićanac, Katarina Davalieva, Marijana Petković

“…A spectral analysis, complemented by statistics, revealed that the Pd(II) complex considerably affected all major types of macromolecules in HeLa cells and induced structural changes in proteins through an increased formation of cross-β-sheets and causes structural rearrangement in deoxyribonucleic acid (DNA) through potential chromosome fragmentation. …”
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Advances in the Study of Bioactive Compounds and Nutraceutical Properties of Goji Berry (<i>Lycium barbarum</i> L.) by Xin Shi, Xiaojing Wang, Yuhong Zheng, Li Fu

“…Goji berries contain significant amounts of carbohydrates (46–87% dry weight), proteins (5.3–14.3% dry weight), and dietary fiber (3.63–16 g/100 g fresh weight). …”
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