Cellular electron tomography of the apical complex in the apicomplexan parasite Eimeria tenella shows a highly organised gateway for regulated secretion. by Alana Burrell, Virginia Marugan-Hernandez, Richard Wheeler, Flavia Moreira-Leite, David J P Ferguson, Fiona M Tomley, Sue Vaughan

“…Finally, we provide ultrastructural evidence for fusion of rhoptries directly through the parasite plasma membrane early in infection and the presence of a pore in the parasitophorous vacuole membrane, providing a structural explanation for how rhoptry proteins may be trafficked between the parasite and the host cytoplasm.…”
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Mechanistic Insights into the Inhibition of Colorectal Cancer by BuShenFang through Adenomatous Polyposis Coli Expression and Wnt/β-catenin Pathway Regulation by Khang Wen Goh, Jie Ji, Hiu Ching Phang, Xian Gu, Rajesh Sreedharan Nair, Xiaohui Wei, Mohammed Tahir Ansari, Kai Bin Liew

“…Furthermore, Western blot results revealed that BSF enhanced adenomatous polyposis coli (APC) expression and inhibited β-catenin, c-Myc, and Cyclin D1, key proteins in the Wnt/β-catenin pathway. In conclusion, BSF exerts anti-CRC effects by modulating the Wnt/β-catenin pathway, suggesting its potential as a complementary therapeutic agent in CRC treatment. …”
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Permeation Peptide Conjugates for In Vivo Molecular Imaging Applications by Kristin E. Bullok, Seth T. Gammon, Stefania Violini, Andrew M. Prantner, Victor M. Villalobos, Vijay Sharma, David Piwnica-Worms

“…Membrane permeant peptides based on the HIV-1 Tat basic domain sequence, GRKKRRQRRR, labeled with fluorophores and fluorescent proteins for optical imaging or with appropriate peptide-based motifs or macrocycles to chelate metals, such as technetium for nuclear scintigraphy and gadolinium for magnetic resonance imaging, have been synthesized. …”
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Design and modeling of a nanocomposite system for demineralization of sweet whey by Mina Rezapour, Mohsen Esmaiili, Mehdi Mahmoudian, Alireza Behrooz Sarand

“…Consequently, the recovery of whey proteins from industrial whey using fabricated membranes in a cross-flow membrane module was also investigated. …”
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Phytocannabinoids: a new frontier in Alzheimer’s disease management by Jagadeesh S. Rao

“…Studies have shown that administering low amounts of THC can reduce the phosphorylation of tau, the accumulation of beta-amyloid proteins, and the levels of GSK3 beta. Moreover, it has the potential to enhance mitochondrial function. …”
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The clinical significance of SNAIL, TWIST, and E-Cadherin expression in gastric mesentery tumor deposits of advanced gastric cancer by Haiyan Wu, Yanping Chen, Huimei Lin, Yanchang Xu, Zipei Guo, Zhixiong Li

“…Conclusion: The occurrence and development of gastric cancer and the formation of TDs may be related to EMT, analyzing the expression of EMT-related transforming proteins may be helpful to judge the prognosis of gastric cancer.…”
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Synergistic Apoptotic Effect of Crocin and Paclitaxel or Crocin and Radiation on MCF-7 Cells, a Type of Breast Cancer Cell Line by Faeze Vali, Vahid Changizi, Majid Safa

“…To investigate the apoptotic effect of experimental groups PI-flow cytometry was used and expression of apoptotic proteins (caspase-7, caspase-9, PARP, and p53) was studied by western blot. …”
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Rapid Discrimination of Cheese Products Based on Probabilistic Neural Network and Raman Spectroscopy by Zheng-Yong Zhang

“…The experimental results show that the spectrum contains abundant molecular vibration information of carbohydrates, fats, proteins, and other components, and the Raman spectral data collection time of a single sample is only 100 s. …”
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Sideroflexin family genes were dysregulated and associated with tumor progression in prostate cancers by Hua Huang, Huibo Lian, Wang Liu, Benyi Li, Runzhi Zhu, Haiyan Shao

“…Abstract Sideroflexin (SFXN) family genes encode for a group of mitochondrial proteins involved in cellular processes such as iron homeostasis, amino acid metabolism, and energy production. …”
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Hypobaric Hypoxia Imbalances Mitochondrial Dynamics in Rat Brain Hippocampus by Khushbu Jain, Dipti Prasad, Shashi Bala Singh, Ekta Kohli

“…Mitochondrial morphology, distribution within neurons, enzyme activity of respiratory complexes, Δψm, ADP: ATP, and expression of fission/fusion key proteins were determined. Results demonstrated HH induced alteration in mitochondrial morphology by damaged, small mitochondria observed in neurons with disturbance of mitochondrial functionality and reduced mitochondrial density in neuronal processes manifested by excessive mitochondrial fragmentation (fission) and decreased mitochondrial fusion as compared to unexposed rat brain hippocampus. …”
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DNA mismatch repair (MMR) genes expression in lung cancer and its correlation with different clinicopathologic parameters by Mayada Saad Farrag, Heba Wagih Abdelwahab, Amr Abdellateef, Nahla Anber, Mohamed Adel Ellayeh, Dalia Tawfeek Hussein, Ahmed Ramadan Eldesoky, Heba Sheta

“…We recommend evaluation of the four proteins as a biomarker that could guide LC therapy. …”
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Biofilm removal mediated by Salmonella phages from chicken-related sources by Zhenzhen Ning, Lingling Zhang, Linlin Cai, Xinglian Xu, Ying Chen, Huhu Wang

“…Raman analysis found that carbohydrates and proteins were the identification receptors for scattered EPS. …”
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Computational screening, synthesis and neuroprotective evaluation of small molecule for the treatment of alzheimer's disease by Nerlis Pajaro-Castro, Elkin Torres-Sierra, Edwar Cortes-Gonzalez, Margaret Paternina, Erwin Camacho, Pedro Blanco

“…METHODS: Using AutoDock Vina, compounds with drug-like properties were docked against key proteins implicated in Alzheimer's pathology: β-Secretase, γ-Secretase, Pin1, and Cdk5. …”
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Oligodendrocyte Injury in Multiple Sclerosis. by Mateo Përgjegji, Klei Bame, Ketrina Ceka, Jera Cenalia , Sibora Bërdica , Teona Bushati

“…This disease arises from a complex interplay of genetic predispositions and environmental triggers that drive immune-mediated damage to oligodendrocytes and myelin proteins. This research paper explores the multifaceted aspects of oligodendrocyte injury in MS, ranging from underlying pathophysiological mechanisms to potential therapeutic interventions and translational implications for clinical practice. …”
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Pseudomonas syringae lytic transglycosylase HrpH interacts with host ubiquitin ligase ATL2 to modulate plant immunity by Jun-Zhou Li, Yi-Lin Gu, Wei Zhang, Shen Cong, Ruo-Na Wang, Yi-Nan Ma, Ya Jin, Hai-Lei Wei

“…Summary: Pseudomonas syringae deploys a type III secretion system (T3SS) to deliver effector proteins to facilitate infection of plant cells; however, little is known about the direct interactions between T3SS components and plants. …”
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Oral Allergy Syndrome in a Child Provoked by Royal Jelly by Fantini Paola, Delle Donne Pantalea, Calogiuri Gianfranco, Ferrannini Antonio, Vacca Angelo, Nettis Eustachio, Di Leo Elisabetta

“…The specific IgE by ImmunoCAP System method versus Hymenoptera venom, inhalant allergens, food allergens, and lipid transfer proteins was dosed. According to the positive reactions to royal jelly both by prick-by-prick test and by a first reading patch test, royal jelly immediate hypersensitivity was diagnosed. …”
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An ingestible bioimpedance sensing device for wireless monitoring of epithelial barriers by Brian M. Holt, Justin M. Stine, Luke A. Beardslee, Hammed Ayansola, Younggeon Jin, Pankaj J. Pasricha, Reza Ghodssi

“…In the GI tract, local inflammatory processes induce alterations in tight junction proteins, enhancing paracellular ion permeability. …”
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Immunoglobulin Gamma-Like Therapeutic Bispecific Antibody Formats for Tumor Therapy by Shixue Chen, Lingling Li, Fan Zhang, Yu Wang, Yi Hu, Lei Zhao

“…Bispecific antibodies (BsAbs) are a sort of dual functional proteins with specific binding to two distinct targets, which have become a focus of interest in antibody engineering and drug development research and have a promising future for wide applications in cancer immunotherapy and autoimmune disease. …”
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Alternative Splicing of Cdh23 Exon 68 Is Regulated by RBM24, RBM38, and PTBP1 by Nana Li, Haibo Du, Rui Ren, Yanfei Wang, Zhigang Xu

“…Alternative splicing plays a pivotal role in modulating the function of eukaryotic proteins. In the inner ear, many genes undergo alternative splicing, and errors in this process lead to hearing loss. …”
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Platinum(II) Complexes with Tetradentate Schiff Bases as Ligands: Synthesis, Characterization and Detection of DNA Interaction by Differential Pulse Voltammetry by Lijun Li, Chao Tian, Cheng Wang, Guangyuan Wang, Lianzeng Wang, Jianlong Du

“…The sterical hindrance of antitumor drug candidates potentially makes them less susceptible to deactivation by sulphur containing proteins and helping to overcome resistance mechanisms. …”
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