RESPONSE OF WHEAT TO DIFFERENT ABIOTIC STRESS CONDITIONS: A REVIEW by Harikala Paudel, Radhakrishna Bhandari, Anjali Dhakal, Shivalal Nyaupane, Binod Panthi, Mukti Ram Poudel

“…The plant has earliness as a phenological, rolling of leaves as morphological, waxiness as physiological, and production of heat shock proteins and proline content as a biochemical defense. …”
Get full text

Traffic Control of Bacteria-Derived Molecules: A New System of Host-Bacterial Crosstalk by Hiroaki Konishi, Mikihiro Fujiya, Yutaka Kohgo

“…Virulent microorganisms, such as pathogenic bacteria and viruses, are recognized by pattern recognition receptors (PRRs), including toll-like receptors (TLRs) and nucleotide-binding oligomerization-domain proteins (NODs), and induce inflammatory responses in mammalian hosts. …”
Get full text

Klebsiella pneumoniae Biofilms and Their Role in Disease Pathogenesis by Maria Eduarda Souza Guerra, Giulia Destro, Brenda Vieira, Alice S. Lima, Lucio Fabio Caldas Ferraz, Anders P. Hakansson, Michelle Darrieux, Thiago Rojas Converso

“…Biofilms are complex bacterial communities composed of one or more species encased in an extracellular matrix made of proteins, carbohydrates and genetic material derived from the bacteria themselves as well as from the host. …”
Get full text

Ribosomes: An Exciting Avenue in Stem Cell Research by Zhenzhen Han, Qi Zhang, Yanbo Zhu, Jingcheng Chen, Wei Li

“…Majority of living organisms possess ribosomes that are involved in the translation of mRNA into proteins and promote cellular proliferation and differentiation. …”
Get full text

Three anti-inflammatory polysaccharides from Lonicera japonica Thunb.: insights into the structure-function relationships by Yu Liu, Hongjing Dong, Dongxiao Sun-Waterhouse, Wenwen Li, Bin Zhang, Jinqian Yu, Zhichang Qiu, Zhenjia Zheng

“…They exhibited excellent protective effects (in a dose-dependent manner) in lipopolysaccharide-injured RAW264.7 macrophages and CuSO4-damaged zebrafish via reducing NO production and inhibiting the overexpressions of inflammation-related transcription factors, inflammatory proteins and cytokines in the NF-κB/MAPK signaling pathways. …”
Get full text

Mechanistic Framework for Establishment, Maintenance, and Alteration of Cell Polarity in Plants by Pankaj Dhonukshe

“…In plants, auxin efflux carrier PIN proteins display polar localizations in various cell types and play major roles in directional cell-to-cell transport of signaling molecule auxin that is vital for plant patterning and response programs. …”
Get full text

Biological Synthesis of Silver Nanoparticles by Cell-Free Extract of Spirulina platensis by Gaurav Sharma, Nakuleshwar Dut Jasuja, Manoj Kumar, Mohammad Irfan Ali

“…FTIR and UV-Vis spectra showed that biomolecules, proteins and peptides, are mainly responsible for the formation and stabilisation of AgNPs. …”
Get full text

Use of a microfluidic platform to uncover basic features of energy and environmental stress responses in individual cells of Bacillus subtilis. by Matthew T Cabeen, Jonathan R Russell, Johan Paulsson, Richard Losick

“…However, mutant cells producing only one of the four paralogous RsbR stressosome proteins showed striking and previously unseen differences. …”
Get full text

Development of RNA interference-based therapy for rare genetic diseases by Milya Urfa Ahmad, Syarifah Dewi

“…RNAi employs small RNA molecules, such as small interfering RNA (siRNA) and microRNA (miRNA), to bind specific mRNA molecules and prevent their translation into proteins. Current research showed that RNAi-based therapies have the potential to treat various genetic diseases, including acute hepatic porphyria (AHP) and primary hyperoxaluria type 1 (PH1). …”
Get full text

Physiological consequences of Aldolase C deficiency during lactation. by James A Votava, Jing Fan, Brian W Parks

“…Aldoc is also a transcriptional target of the sterol regulatory element binding proteins 1 and 2 (Srebp1 and Srebp2), which transcriptionally regulate enzymes within the DNL pathway and has recently been shown to regulate plasma cholesterol and triglycerides. …”
Get full text

Study on Apoptosis of Prostate Cancer Cells Induced by IκBα Overexpression Synergistic with Poly (Lactic-Co-Glycolic Acid)-Curcumin Nanoparticles by Hui Guo, Jianwen Huang, Hongbin Li, Ranxing Yang, Rong Chen

“…The expression levels of IκBα, apoptosis-related, and signaling proteins were measured by western blotting assay. Results. …”
Get full text

Essential Oils May Lead α-Synuclein towards Toxic Fibrils Formation by Dina Morshedi, Mahour Nasouti

“…However, major components of M. communis did not induce fibrillation and also the effect of M. communis was limited on other fibrinogenic proteins. Assuming that essential oils have the ability to pass through the blood brain barrier (BBB) along with the popular attention on aromatherapy for the incurable ND, these findings suggest an implementation of fibrillation tests for essential oils.…”
Get full text

Spectroscopically Well-Characterized RGD Optical Probe as a Prerequisite for Lifetime-Gated Tumor Imaging by Julia Eva Mathejczyk, Jutta Pauli, Christian Dullin, Joanna Napp, Lutz-F. Tietze, Horst Kessler, Ute Resch-Genger, Frauke Alves

“…The fluorescence quantum yield and lifetime of Cy5.5 were found to be barely affected on RGD conjugation but dramatically changed in the presence of proteins. By time domain fluorescence imaging, we demonstrated specific binding of RGD-Cy5.5 to glioblastoma xenografts in nude mice. …”
Get full text

Annexin V–CLIO: A Nanoparticle for Detecting Apoptosis by MRI by Eyk A. Schellenberger, Alexei Bogdanov, Dagmar Högemann, Jonathan Tait, Ralph Weissleder, Lee Josephson

“…The resulting nanoparticle had an average of 2.7 annexin V proteins linked per CLIO nanoparticle through disulfide bonds. …”
Get full text

Articular Cartilage Repair Using Marrow Stimulation Augmented with a Viable Chondral Allograft: 9-Month Postoperative Histological Evaluation by James K. Hoffman, Sandra Geraghty, Nicole M. Protzman

“…The chondral allograft is comprised of native viable chondrocytes, chondrogenic growth factors, and extracellular matrix proteins within the superficial, transitional, and radial zones of hyaline cartilage. …”
Get full text

Martini compatible coarse-grained model of polyethylenimine for pulmonary gene delivery by Graham Lunt, Niloofar Hashemi, Subhamoy Mahajan, Tian Tang

“…Special attention is focused on parameterizing the non-bonded interactions associated with CG PEI, to ensure compatibility with Martini proteins, short interfering RNA, and phospholipids that are essential components in pulmonary gene delivery. …”
Get full text

Matched serum- and urine-derived biomarkers of interstitial cystitis/bladder pain syndrome. by Tadeja Kuret, Igor Sterle, Rok Romih, Peter Veranič

“…A total of 33 different biomarkers were measured, including cytokines and chemokines, proteins involved in extracellular matrix remodeling, adhesion molecules, growth factors, and markers of oxidative stress using enzyme linked immunoassays and multiplex technology. …”
Get full text

The Liver X Receptor Promotes Immune Homeostasis via Controlled Activation of the Innate Immune System in the Liver by Hiroyuki Nakashima, Bradley M. Kearney, Manabu Kinoshita

“…However, the transport of these materials from the liver is an energetically intensive task because they contain a considerable number of hydrophobic components, including free cholesterol, and require specialized transfer proteins to shuttle these substances through an aqueous phase. …”
Get full text

Salivary Biomarkers in Periodontitis Patients: A Pilot Study by Sarah Reddahi, Amal Bouziane, Sana Rida, Houssain Tligui, Oumkeltoum Ennibi

“…The concentration of these proteins in saliva showed a significant association with gingival index and pocket depth measurements and may reflect the clinical status of healthy and diseased periodontium. …”
Get full text

Nature of viruses and the radical change in viral taxonomy by V. V. Makarov, L. P. Buchatsky

“…Changes in the rank hierarchy are based on the evolution of the recognition of virus taxa over time, from a traditional phenotype-based characterization process to a multistage process that includes comparative sequence analyses of conserved genes and proteins, including gene phylogeny, gene synteny and shared gene content. …”
Get full text