Chain Gangs: New Aspects of Hyaluronan Metabolism by Michael Erickson, Robert Stern

“…Hyaluronan provides a scaffold on which sulfated proteoglycans and matrix proteins are organized. These supramolecular structures are able to entrap water and ions to provide tissues with hydration and turgor. …”
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Early changes in microRNA expression in Arabidopsis plants infected with the fungal pathogen Fusarium graminearum. by Savio S Ferreira, Suman Pandey, Jesseca Hemminger, Serdar Bozdag, Mauricio S Antunes

“…Triggering these different defense processes requires orchestration of a network of proteins and RNA molecules that includes microRNAs (miRNAs). …”
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Contribution of Filopodia to Cell Migration: A Mechanical Link between Protrusion and Contraction by Fei Xue, Deanna M. Janzen, David A. Knecht

“…We have found that although filopodia contain parallel bundles of actin, they contain a surprisingly nonuniform spatial and temporal distribution of actin binding proteins. Along the length of the actin filaments in a single filopodium, the most distal portion contains primarily T-plastin, while the proximal portion is primarily bound by α-actinin and coronin. …”
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Serological characteristics and immunohematological difficulties in autoimmune hemolytic anemia patients: A retrospective analytical study from South India by Dibyajyoti Sahoo, S. Anuragaa

“…The antibodies may be immunoglobulin G, immunoglobulin M, immunoglobulin A, or complement proteins, and hemolysis may be intravascular or extravascular. …”
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Management of Coagulopathy in Patients with Decompensated Liver Cirrhosis by Pooja D. Amarapurkar, Deepak N. Amarapurkar

“…Patients with decompensated liver cirrhosis have significantly impaired synthetic function. Many proteins involved in the coagulation process are synthesized in the liver. …”
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Exploring the maternal inheritance transmitted by the oocyte to its progeny by Verlhac, Marie-Hélène

“…This is what can be defined as the maternal inheritance composed of chromosomes, organelles, lipids, metabolites, proteins and RNAs. To decipher the decline in oocyte quality, it is essential to explore the nature of the maternal inheritance, and therefore study the last stages of murine oogenesis, namely the end of oocyte growth followed by the two meiotic divisions. …”
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Mesenchymal stem cells from perinatal tissues promote diabetic wound healing via PI3K/AKT activation by Jiawei Huang, Qingwen Deng, Lai Ling Tsang, Guozhu Chang, Jinghui Guo, Ye Chun Ruan, Chi Chiu Wang, Gang Li, Hon Fai Chan, Xiaohu Zhang, Xiaohua Jiang

“…Mass spectrometry was used to analyze the secreted proteins of the MSCs. We incorporated the MSCs into a polyethylene glycol diacrylate (PEGDA) and sodium alginate (SA) hydrogel matrix with collagen I (Col-I) to evaluate their effects on wound healing. …”
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Rheumatic Diseases and Obesity: Adipocytokines as Potential Comorbidity Biomarkers for Cardiovascular Diseases by Rossana Scrivo, Massimiliano Vasile, Ulf Müller-Ladner, Elena Neumann, Guido Valesini

“…The inflammatory process underlying the cardiovascular risk both in obesity and RA may be mediated by adipocytokines, a heterogeneous group of soluble proteins mainly secreted by the adipocytes. Many adipocytokines are mainly produced by white adipose tissue. …”
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Beyond gluten-free diet: a critical perspective on phase 2 trials on non-dietary pharmacological therapies for coeliac disease by Davide Scalvini, Chiara Scarcella, Giulia Mantica, Erica Bartolotta, Stiliano Maimaris, Erica Fazzino, Federico Biagi, Federico Biagi, Annalisa Schiepatti, Annalisa Schiepatti

“…Coeliac disease is an immune-mediated chronic enteropathy, with a prevalence of around 1% in the general population and occurring in genetically susceptible individuals after the ingestion of gluten proteins present in wheat, rye and barley. Currently, a strict lifelong gluten-free diet is the cornerstone of treatment of coeliac disease. …”
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Interaction mechanism of egg white- derived ACE inhibitory peptide TNGIIR with ACE and its effect on the expression of ACE and AT1 receptor by Zhipeng Yu, Hui Guo, David Shiuan, Chensi Xia, Wenzhu Zhao, Long Ding, Fuping Zheng, Jingbo Liu

“…Keywords: Egg white proteins, ACE inhibitory peptide, Gene expression, Antihypertensive effect, Molecular docking…”
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Autonomous Defense Based on Biogenic Nanoparticle Formation in Daunomycin-Producing <i>Streptomyces</i> by Karel Beneš, Vladislav Čurn, Baveesh Pudhuvai, Jaroslav Motis, Zuzana Michalcová, Andrea Bohatá, Jana Lencová, Jan Bárta, Michael Rost, Andreas Vilcinskas, Vladimír Maťha

“…The characterization of the nanoparticles confirmed the incorporation of iron and daunomycin, indicating that this approach has the potential to mitigate cytotoxicity while improving yields. The presence of proteins associated with iron homeostasis and oxidative stress responses revealed the ability of the production strain to adapt to high iron concentrations. …”
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Salmon Muscle Adherence to Polymer Coatings and Determination of Antibiotic Residues by Reversed-Phase High-Performance Liquid Chromatography Coupled to Selected Reaction Monitorin... by E. Zumelzu, M. J. Wehrhahn, O. Muñoz, F. Rull

“…No evidence of antibiotics was observed on the protective coating in the range between 0.001 and 2.0 ng/mL; however, the presence of proteins, cholesterol, and alpha-carotene was detected. …”
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Emerging targets of α-synuclein spreading in α-synucleinopathies: a review of mechanistic pathways and interventions by Grace Kuo, Ramhari Kumbhar, William Blair, Valina L. Dawson, Ted M. Dawson, Xiaobo Mao

“…Recognizing the intricate complexity and multifactorial etiology of α-synucleinopathy, the review illuminates the potential of various membrane receptors, proteins, intercellular spreading pathways, and pathological agents for therapeutic interventions. …”
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Biofilm Compositions and Bacterial Diversity on Kitchen Towels in Daily Use by Yao Zhang, Kexin Li, Yibo Ru, Yue Ma

“…The bacteria concentrations ranged from 4 to 7 log CFU/g. Proteins were the most abundant EPS, followed by polysaccharides and eDNA. …”
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HPV-Based Screening, Triage, Treatment, and Followup Strategies in the Management of Cervical Intraepithelial Neoplasia by Oscar Peralta-Zaragoza, Jessica Deas, Claudia Gómez-Cerón, Wendy Argelia García-Suastegui, Geny del Socorro Fierros-Zárate, Nadia Judith Jacobo-Herrera

“…Thus, the identification and subsequent functional evaluation of host proteins associated with HPV E6 and E7 oncoproteins may provide useful information in understanding cervical carcinogenesis, identifying cervical cancer molecular markers, and developing specific targeting strategies against tumor cells. …”
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Prednisone inhibits osteosarcoma cell by regulating the Wnt/β-catenin signaling pathway by Yo Zhang, Hongmei Zhang, Shanshan Yang, Xiufeng Gao, Wenhao Guo

“…To investigate the effect of prednisone on osteosarcoma cells in vitro, CCK8, wound healing, Transwell assays, flow-cytometry, western blot, and ELISA were used to measure cell proliferation, cell migration, cell invasion, cell cycle, cell apoptosis, and the key proteins in Wnt/β-catenin pathway. The results showed prednisone could inhibit the proliferation in osteosarcoma cells and exhibit lower proliferation toxicity towards normal bone cells compared to cisplatin by 17.5% (p<0.001). …”
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An Emerging Role of Glucagon-Like Peptide-1 in Preventing Advanced-Glycation-End-Product-Mediated Damages in Diabetes by Alessandra Puddu, François Mach, Alessio Nencioni, Giorgio Luciano Viviani, Fabrizio Montecucco

“…Since chronic hyperglycemia contributed to the acceleration of the formation of Advanced Glycation End-Products (AGEs, a heterogeneous group of compounds derived from the nonenzymatic reaction of reducing sugars with free amino groups of proteins implicated in vascular diabetic complications), the administration of GLP-1 might directly counteract diabetes pathophysiological processes (such as pancreatic β-cell dysfunction). …”
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The Influence of Interfering Substances on the Antimicrobial Activity of Selected Quaternary Ammonium Compounds by Paula A. Araújo, Madalena Lemos, Filipe Mergulhão, Luís Melo, Manuel Simões

“…Standard cleaning processes may not remove all the soiling typically found in food industry, such as carbohydrates, fats, or proteins. Contaminants have a high impact in disinfection as their presence may reduce the activity of disinfectants. …”
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Inflammatory Bowel Disease: An Overview of Immune Mechanisms and Biological Treatments by Bruno Rafael Ramos de Mattos, Maellin Pereira Gracindo Garcia, Julia Bier Nogueira, Lisiery Negrini Paiatto, Cassia Galdino Albuquerque, Caique Lopes Souza, Luís Gustavo Romani Fernandes, Wirla Maria da Silva Cunha Tamashiro, Patricia Ucelli Simioni

“…Nowadays, advances in treatments for IBD have included biological therapies, based mainly on monoclonal antibodies or fusion proteins, such as anti-TNF drugs. Notwithstanding the high cost involved, these biological therapies show a high index of remission, enabling a significant reduction in cases of surgery and hospitalization. …”
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Ribosomes translocation into the spore of Bacillus subtilis is highly organised and requires peptidoglycan rearrangements by Olga Iwańska, Przemysław Latoch, Mariia Kovalenko, Małgorzata Lichocka, Joanna Hołówka, Remigiusz Serwa, Agata Grzybowska, Jolanta Zakrzewska-Czerwińska, Agata L. Starosta

“…We propose that the movement of ribosomes in the cell may be mediated by the bacterial homologs of cytoskeletal proteins and that the cues for asymmetric division localisation may be translation-dependent. …”
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