Detection of new single nucleotide polymorphisms in plasma cells carcinoma (myeloma) by polymerase chain reaction–single strand conformation polymorphism and sequencing technical m... by Sarah K. Obayes, Sabah H. Enayah, Shaimaa A. Al-Oubaidy, Rana A. Ghaleb

“…Abstract Background: MicroRNA (miRNA) is a short, single-stranded, non-coding sequence of RNA that does not translate into proteins. Because of their ability to control gene expression, recent studies have shown that these short, non-coding sequences play an important role in cancer. …”
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Dieta by Alfredo Darío Espinosa Brito, Frank Carlos Álvarez Li

“…Elements for the minimum and maximum consumption of fats, carbohydrates and proteins as to energy requirements of individuals are provided as well as content charts on cholesterol, dietary fiber and salt, according to different types of food. …”
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Response of host immune system to tick borne encephalitis virus by Iveta Stibraniova, Pavlina Bartikova, Jozef Dzubara

“…Components of innate immunity - natural killer cells, complement proteins, macrophages and dendritic cells usually provide rapid and intense protection in the acute phase of infectious diseases. …”
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Tamarind Seed Xyloglucans Promote Proliferation and Migration of Human Skin Cells through Internalization via Stimulation of Proproliferative Signal Transduction Pathways by W. Nie, A. M. Deters

“…Independent of cell type TSw marginally regulated the expression of genes, which referred to membrane proteins, cytoskeleton, cytokine signaling, and ECM as well as to processes of metabolism and transcription. …”
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Bat population dynamics: multilevel model based on individuals' energetics by Paula Federico, Dobromir T. Dimitrov, Gary F. McCracken

“…Our individual component describes the growth of an individual female bat by modeling the dynamics of the main body compartments (lipids, proteins, and carbohydrates). A structured population model based on extended McKendrick-von Foerster partial differential equations integrates those individual dynamics and provides insight into possible regulatory mechanisms of population size as well as conditions of population survival and extinction. …”
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Nanomédicaments pour le traitement de maladies graves et recherches duales by Couvreur, Patrick

“…This review aims to describe and discuss the characteristics and functionalities of the different generations of nanocarriers, from their inception to the present day, discussing the prospects they offer for the production of therapeutic proteins, for facilitating gene editing (CRISPR/Cas9), and for enabling immune checkpoint blockade in oncology. …”
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Molecular Basis for Mucolytic Therapy by Bonnie Dasgupta, Malcolm King

“…It is composed of water, mucous glycoproteins, low molecular weight ions, proteins and lipids. The three-dimensional structure of the mucous gel depends on a number of forms of bonding, such as ionic bonds and disulphide bridges. …”
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St-N, a novel alkaline derivative of stevioside, reverses docetaxel resistance by targeting lysosomes in vitro and in vivo. by Yanxia Guo, Shikang Wang, Qun Liu, Yan Dong, Yongqing Liu

“…St-N destabilized lysosomal membrane by impairing lysosomal membrane proteins and acid sphingomyelinase. As a result, St-N caused cathepsins to release from the lysosomes into the cytosol, eventually triggering apoptotic and necrotic cell death. …”
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Essential Role of Zinc and Zinc Transporters in Myeloid Cell Function and Host Defense against Infection by Muna Sapkota, Daren L. Knoell

“…An additional work in this field has revealed a vital role for several zinc transporter proteins that are required for proper bioredistribution of zinc within mononuclear cells to achieve an optimal immune response against invading microorganisms. …”
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Targeting heparan sulfate proteoglycans as an effective strategy for inhibiting cancer cell migration and invasiveness compared to heparin by Lorenzo Depau, Jlenia Brunetti, Chiara Falciani, Elisabetta Mandarini, Marta Zanchi, Maria Francesca Paolocci, Marta Garfì, Alessandro Pini, Luisa Bracci

“…By virtue of their ability to bind different growth factors, morphogens and extracellular matrix proteins, heparan sulfate proteoglycans (HSPGs) play a determinant role in cancer cell differentiation and migration. …”
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Understanding the Role of Exercise in Nonalcoholic Fatty Liver Disease: ERS-Linked Molecular Pathways by Yong Zou, Zhengtang Qi

“…Higher ERS may lead to increased inflammation and apoptosis in the liver, while lower ERS may lead to the accumulation of misfolded proteins. Therefore, exercise acts like an igniter or extinguisher to keep ERS at an appropriate level by turning it up or down, which depends on diet, medications, exercise intensity, etc. …”
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Widespread release of translational repression across Plasmodium's host-to-vector transmission event. by Kelly T Rios, James P McGee, Aswathy Sebastian, Sanjaya Aththawala Gedara, Robert L Moritz, Marina Feric, Sabrina Absalon, Kristian E Swearingen, Scott E Lindner

“…Therefore, female gametocytes proactively produce and translationally repress mRNAs that encode essential proteins that the zygote requires to establish a new infection. …”
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Selenium and Thyroid Disease: From Pathophysiology to Treatment by Mara Ventura, Miguel Melo, Francisco Carrilho

“…Selenium is a micronutrient embedded in several proteins. In adults, the thyroid is the organ with the highest amount of selenium per gram of tissue. …”
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How Bacteria-Induced Apoptosis of Intestinal Epithelial Cells Contributes to Mucosal Inflammation by Martin Hausmann

“…Endoplasmic reticulum (ER) stress causes misfolded proteins to accumulate in the ER lumen. It was suggested that ER stress and autophagy may interact within intestinal epithelial cells. …”
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Combination Immunosuppressive Therapy in Primary Autoimmune Inner Ear Disease in Pregnancy by Saikrishna Ananthapadmanabhan, Joe Jabbour, David Brown, Vanaja Sivapathasingam

“…The pathophysiology is likely driven by chronic trafficking of immune cells into the inner ear, targeting inner ear proteins to coordinate inflammation. Suppression or modulation of the immune response can minimize cochleitis allowing for potential recovery of hearing. …”
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The Science of Memory Loss: Insights into Alzheimer’s Disease by Agnieszka Starzyk, Piotr Charzewski

“…Emerging therapies, such as monoclonal antibodies targeting amyloid-beta and tau proteins, show promise but are hindered by challenges in efficacy and safety. …”
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Update on New Antigens in the Pathogenesis of Membranous Nephropathy by Maurizio Salvadori, Aris Tsalouchos

“…The availability of novel techniques such as laser micro-dissection and tandem mass spectrometry, as well as immunochemistry with antibodies directed against novel proteins, allowed the confirmation of new antigens involved. …”
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The potential of fluorogenicity for single molecule FRET and DyeCycling by Srijayee Ghosh, Sonja Schmid

“…Single Molecule Förster Resonance Energy Transfer (smFRET) is a popular technique to directly observe biomolecular dynamics in real time, offering unique mechanistic insight into proteins, ribozymes, and so forth. However, inevitable photobleaching of the fluorophores puts a stringent limit on the total time a surface-tethered molecule can be monitored, fundamentally limiting the information gain through conventional smFRET measurements. …”
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Influence of Light Intensity on Tobacco Responses to Drought Stress by Brwa Rasool

“…A transcriptome profiling analysis of the tobacco responses to light intensity highlights the increased abundance of a large group of drought-related transcripts including DROUGHT-RESPONSIVE ELEMENT BINDING FACTORS (DREBs), C-REPEAT/DROUGHT-RESPONSIVE BINDING FACTOR 1 (CBF1), GLYCINE-RICH RNA BINDING PROTEINS (GRPs), WRKY33 and MYCs transcription factors, as well as zeaxanthin epoxidase, which play as a regulator of plant responses to water deficient condition. …”
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Floral Nectary Anatomy and Ultrastructure in Mycoheterotrophic Plant, Epipogium aphyllum Sw. (Orchidaceae) by Emilia Święczkowska, Agnieszka K. Kowalkowska

“…The exudation on papillae has been observed through the entire anthesis and it has been stained on polysaccharides, proteins, and lipids. The dense cytoplasm of papillae contains profuse endoplasmic reticulum, plentiful vesicles (bigger ones with tannin-like materials), numerous mitochondria, sometimes dictyosomes, starch grains, and plastids with tubular structures. …”
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