Showing 14,041 - 14,060 results of 15,527 for search '"protein"', query time: 0.10s Refine Results
  1. 14041

    Biophysical aspects of mechanotransduction in cells and their physiological/biological implications in vocal fold vibration: a narrative review by Junseo Cha, Susan L. Thibeault

    Published 2025-01-01
    “…Recent studies have identified mechanosensitive proteins in vocal fold epithelia, supporting this hypothesis. …”
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    Article
  2. 14042

    Disturbances in the Mechanism of Apoptosis as One of the Causes of the Development of Cancer Diseases by Paweł Rusin, Karolina Jabłońska

    Published 2020-12-01
    “…New types of molecular therapies provide an opportunity to increase the effectiveness of anticancer treatment, aiming at deficient proteins and suppressing or eliminating their antiapoptotic effects.…”
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    Article
  3. 14043

    Developments in Diagnosis and Antileishmanial Drugs by Prachi Bhargava, Rajni Singh

    Published 2012-01-01
    “…This provides the promise that many of the parasite’s proteins should be sufficiently different from hosts and can be successfully exploited as drug targets. …”
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    Article
  4. 14044

    In Vivo Pharmacodynamic Imaging of Proteasome Inhibition by Erin A. Kimbrel, Tina N. Davis, James E. Bradner, Andrew L. Kung

    Published 2009-05-01
    “…Toward this end, ectopic fusion of the destruction domain from ornithine decarboxylase (ODC) to reporter proteins is often used for assessing proteasome function. …”
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    Article
  5. 14045

    The Role of TGFβ Signaling in Squamous Cell Cancer: Lessons from Mouse Models by Adam B. Glick

    Published 2012-01-01
    “…TGFβ1 is a member of a large growth factor family including activins/inhibins and bone morphogenic proteins (BMPs) that have a potent growth regulatory and immunomodulatory functions in normal skin homeostasis, regulation of epidermal stem cells, extracellular matrix production, angiogenesis, and inflammation. …”
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    Article
  6. 14046

    Canonical and noncanonical autophagy: involvement in Parkinson’s disease by Maria Sakurai, Tomoki Kuwahara

    Published 2025-01-01
    “…On the other hand, recent studies have focused on the functions of autophagy proteins beyond intracellular degradation, including noncanonical autophagy, also known as the conjugation of ATG8 to single membranes (CASM), and autophagy-related extracellular secretion. …”
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    Article
  7. 14047

    Role of gp91phox Homolog Nox1 in Induction of Premalignant Spindle Phenotypes of HPV 16 E6/E7—Immortalized Human Keratinocytes by Walee Chamulitrat

    Published 2010-01-01
    “…The NADPH oxidase (Nox) family of superoxide- and hydrogen peroxide—producing proteins has been recognized as important for signal transduction that regulates receptor-mediated functions, including cytoskeleton remodeling, cell proliferation, migration, differentiation, and cell death. …”
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    Article
  8. 14048

    Mathematical modeling of liver fibrosis by Avner Friedman, Wenrui Hao

    Published 2017-01-01
    “…Fibrotic diseases are characterized by abnormal excessive deposition of fibrous proteins, such as collagen, and the disease is most commonly progressive, leading to organ disfunction and failure. …”
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    Article
  9. 14049

    Usefulness of the Vitreous Fluid Analysis in the Translational Research of Diabetic Retinopathy by Olga Simó-Servat, Cristina Hernández, Rafael Simó

    Published 2012-01-01
    “…However, several confounding factors such as vitreous haemorrhage and concentration of vitreous proteins should be considered in the analysis of the results. …”
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    Article
  10. 14050

    Interplay between porin deficiency, fitness, and virulence in carbapenem-non-susceptible Pseudomonas aeruginosa and Enterobacteriaceae. by Hedi Mammeri, Youssouf Sereme, Eya Toumi, Hélène Faury, David Skurnik

    Published 2025-02-01
    “…Porins are outer membrane proteins, which play a key role in the bacterial permeability to allow nutrients to enter and toxic waste to leave. …”
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    Article
  11. 14051

    Expression Profiling of Transglutaminase 2 and Inflammatory Host Response in Aspergillus Fumigatus After Treatment with Curcuma Extracts by Omar Sadik Shalal

    Published 2021-12-01
    “…The current therapies are known for their limitations where they couldn’t target the proteins involved in undoing host response. Here we aimed to screen the possible antifungal role of Curcumin and its effect on the Transglutaminase 2 and Reactive Oxygen species response. …”
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  12. 14052

    Specific receptor usage in Plasmodium falciparum cytoadherence is associated with disease outcome. by Lucy B Ochola, Bethsheba R Siddondo, Harold Ocholla, Siana Nkya, Eva N Kimani, Thomas N Williams, Johnstone O Makale, Anne Liljander, Britta C Urban, Pete C Bull, Tadge Szestak, Kevin Marsh, Alister G Craig

    Published 2011-03-01
    “…In this study we have examined the cytoadherence patterns of 101 patient isolates from varying clinical syndromes to CD36 and ICAM-1, and have used variant ICAM-1 proteins to further characterise this adhesive phenotype. …”
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    Article
  13. 14053

    An Efficient Method for Immortalizing Mouse Embryonic Fibroblasts by CRISPR-mediated Deletion of the Tp53 Gene by Srisathya Srinivasan, Hsin-Yi Ho

    Published 2025-01-01
    “…The MEF system can also be combined with rescue studies to characterize the function of mutant genes/proteins, such as disease-causing variants. However, primary MEFs undergo senescence soon after isolation and passaging, making long-term genetic manipulations difficult. …”
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  14. 14054

    Hepatoprotective Effect of Mitochondria-Targeted Antioxidant Mito-TEMPO against Lipopolysaccharide-Induced Liver Injury in Mouse by Peng-Fei Wang, Ke Xie, Yun-Xing Cao, An Zhang

    Published 2022-01-01
    “…Finally, we found that the levels of pyroptosis-related proteins in the liver of LPS-treated mice were lower after pretreatment with Mito-TEMPO. …”
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    Article
  15. 14055

    The Genetic Basis of Congenital Cataracts: Advances in Diagnostics and Therapeutics by Agnieszka Starzyk, Piotr Charzewski

    Published 2025-02-01
    “…Genetic mutations in structural proteins such as crystallins and connexins account for over half of cases, emphasizing the critical role of early surgical intervention, particularly intraocular lens (IOL) implantation in children over two years old. …”
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    Article
  16. 14056

    Organic Alternatives to Quantum Dots for Intraoperative Near-Infrared Fluorescent Sentinel Lymph Node Mapping by Shunsuke Ohnishi, Stephen J. Lomnes, Rita G. Laurence, Andrew Gogbashian, Giuliano Mariani, John V. Frangioni

    Published 2005-07-01
    “…We present robust methods for the covalent conjugation, purification, and characterization of proteins with tetra-sulfonated heptamethine indocyanines, including mass spectroscopic site mapping of highly substituted molecules. …”
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  17. 14057

    Skin Matters: Identifying Pain Mechanisms and Predicting Treatment Outcomes by Edward A. Shipton

    Published 2013-01-01
    “…Epidermal cells (such as keratinocytes, Langerhans cells, and Merkel cells) express sensor proteins and neuropeptides; these regulate the neuroimmunocutaneous system and participate in nociception and neurogenic inflammation. …”
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    Article
  18. 14058

    Macrophage Polarization in the Osteoarthritis Pathogenesis and Treatment by Xiongfei Zou, Hongjun Xu, Wenwei Qian

    Published 2025-01-01
    “…Additionally, this review discusses potential therapies targeting macrophage polarization, encompassing compounds, proteins, cells, and microRNAs, to offer insights into novel treatment strategies for OA.…”
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    Article
  19. 14059

    Pulmonary Remodeling in Equine Asthma: What Do We Know about Mediators of Inflammation in the Horse? by Ann Kristin Barton, Heidrun Gehlen

    Published 2016-01-01
    “…A systemic involvement has been shown for severe equine asthma by increased acute phase proteins like serum amyloid A and haptoglobin in peripheral blood during exacerbation. …”
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  20. 14060

    Chemical Composition and Nutritional Value of Three Sonchus Species by Galdino Xavier de Paula Filho, Tibério Fontenele Barreira, Helena Maria Pinheiro-Sant’Ana

    Published 2022-01-01
    “…Statistically, fibers and ash presented the same proportions in S. asper and S. arvensis, as well as proteins in S. oleraceus and S. asper species. The availabilities of these vegetables together with their high nutritional value are important factors that contribute to ensuring food security for families that have these species in their diet.…”
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