Established Principles and Emerging Concepts on the Interplay between Mitochondrial Physiology and S-(De)nitrosylation: Implications in Cancer and Neurodegeneration by Giuseppina Di Giacomo, Salvatore Rizza, Costanza Montagna, Giuseppe Filomeni

“…In this paper we aim at summarizing the current knowledge of mitochondria-related proteins undergoing S-nitrosylation and how this redox modification might impact on mitochondrial functions, whose impairment has been correlated to tumorigenesis and neuronal cell death. …”
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A morpho-histological analysis of the exoskeleton of Clathrozoella medeae (Cnidaria, Hydrozoa) reveals insights into the taxonomy of Clathrozoellidae and Hydroidolina by María A. Mendoza-Becerril, Antonio C. Marques

“…The results revealed a three-layered mesoglea, diverse gland cells, and an exoskeleton comprising chitin and structural proteins, with notable differences from other anthoathecate hydroids. …”
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Peroxisome Proliferator-Activated Receptor Gamma and Regulations by the Ubiquitin-Proteasome System in Pancreatic Cancer by Athina Stravodimou, Gianluigi Mazzoccoli, Ioannis A. Voutsadakis

“…It plays generally a tumor suppressor role antagonizing proteins promoting carcinogenesis such as NF-κB and TGFβ. …”
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Impact of three different processing methods on the digestibility and allergenicity of Chinese mitten crab (Eriocheir sinensis) tropomyosin by Yufeng Lu, Huafeng Cheng, Shaotong Jiang, Lin Lin, Jianfeng Lu

“…The tropomyosin (TM) fractions of crab proteins may cause allergic reactions in individuals susceptible to allergies; however, efficient and safe methods by which to reduce such allergenicity are not currently available. …”
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Screening hepatoprotective effective components of Lonicerae japonica Flos based on the spectrum-effect relationship and its mechanism exploring by Song Wang, Lin Yang, Ajiao Hou, Songtao Liu, Liu Yang, Haixue Kuang, Hai Jiang

“…Molecular docking is used to explore the interaction between small molecules and proteins. This work provided a general model of the combination of UPLC-PDA and hepatoprotective effect to study the spectrum-effect relationship of LF, which can be used to considerable methods and insight for the fundamental research of the material basis of similar healthcare food.…”
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Human Cardiospheres as a Source of Multipotent Stem and Progenitor Cells by Lucio Barile, Mihaela Gherghiceanu, Laurenţiu M. Popescu, Tiziano Moccetti, Giuseppe Vassalli

“…They contain a core of primitive, proliferating cells, and an outer layer of mesenchymal/stromal cells and differentiating cells that express cardiomyocyte proteins and connexin 43. Because CSs contain both primitive cells and committed progenitors for the three major cell types present in the heart, that is, cardiomyocytes, endothelial cells, and smooth muscle cells, and because they are derived from percutaneous endomyocardial biopsies, they represent an attractive cell source for cardiac regeneration. …”
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Role of Epstein-Barr Virus and Human Papilloma Virus in the Development of Oropharyngeal Cancer: A Literature Review by Michela Migliaro, Daniela Massuh, María Fernanda Infante, Ana María Brahm, María Trinidad San Martín, Duniel Ortuño

“…It was found that, among the carcinogenic mechanisms of HPV, E6 and E7 proteins are responsible for the malignization process, inhibiting tumor suppressors p53 and pRb. …”
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Data from a multi-year targeted proteomics study of a longitudinal birth cohort of type 1 diabetes by Lisa M. Bramer, Ernesto S. Nakayasu, Javier E. Flores, Jennifer E. Van Eyk, Michael J. MacCoss, Hemang M. Parikh, Thomas O. Metz, Bobbie-Jo M. Webb-Robertson

“…The targeted mass spectrometry assay was comprised of 694 peptides mapping to 167 proteins and the panel was measured in each subject and QC sample. …”
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Distribution of the four type VI secretion systems in Pseudomonas aeruginosa and classification of their core and accessory effectors by Antonia Habich, Verónica Chaves Vargas, Luca A. Robinson, Luke P. Allsopp, Daniel Unterweger

“…Abstract Bacterial type VI secretion systems (T6SSs) are puncturing molecular machines that transport effector proteins to kill microbes, manipulate eukaryotic cells, or facilitate nutrient uptake. …”
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Microtubule flexibility, microtubule-based nucleation and ROP pattern co-alignment enhance protoxylem microtubule patterning by Bas Jacobs, Marco Saltini, Jaap Molenaar, Laura Filion, Eva E. Deinum

“…The development of the water transporting xylem tissue in plants involves an intricate interplay of Rho-of-Plants (ROP) proteins and cortical microtubules to generate highly functional secondary cell wall patterns, such as the ringed or spiral patterns in early-developing protoxylem. …”
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Mechanisms of Chronic State of Inflammation as Mediators That Link Obese Adipose Tissue and Metabolic Syndrome by Eduardo Fuentes, Francisco Fuentes, Gemma Vilahur, Lina Badimon, Iván Palomo

“…Meanwhile, the chronic inflammation in adipose tissue is regulated by a series of transcription factors, mainly PPARs and C/EBPs, that in conjunction regulate the expression of hundreds of proteins that participate in the metabolism and storage of lipids and, as such, the secretion by adipocytes. …”
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Assessment of SREBP Activation Using a Microsomal Vesicle Budding Assay by Mingfeng Xia, Tessa Edwards, Shunxing Rong

“…Sterol regulatory element binding proteins (SREBPs) are transcription factors that reside in the endoplasmic reticulum (ER) membrane as inactive precursors. …”
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Current Understanding on the Heterogenous Expression of Plastic Depolymerising Enzymes in <i>Pichia pastoris</i> by Shuyan Wu, David Hooks, Gale Brightwell

“…Among these systems, the <i>Pichia pastoris</i> expression system has emerged as a widely used platform for producing secreted heterologous proteins. This article provides an overview of studies involving the recombinant expression of polymer-degrading enzymes using the <i>P. pastoris</i> expression system. …”
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Fractional-Order PI Control of First Order Plants with Guaranteed Time Specifications by F. J. Castillo-Garcia, A. San Millan-Rodriguez, V. Feliu-Batlle, L. Sanchez-Rodriguez

“…They contain a core of primitive, proliferating cells, and an outer layer of mesenchymal/stromal cells and differentiating cells that express cardiomyocyte proteins and connexin 43. Because CSs contain both primitive cells and committed progenitors for the three major cell types present in the heart, that is, cardiomyocytes, endothelial cells, and smooth muscle cells, and because they are derived from percutaneous endomyocardial biopsies, they represent an attractive cell source for cardiac regeneration. …”
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Glycosylation Profile of the Transferrin Receptor in Gestational Iron Deficiency and Early-Onset Severe Preeclampsia by Alejandra María Gómez-Gutiérrez, Beatriz Elena Parra-Sosa, Julio Cesar Bueno-Sánchez

“…The increase in Gal-GlcNAc may be due to the increased presence of antennary structures and the mannose glycans of TfR1 may indicate the presence of misfolded or incomplete proteins. These findings may be associated with the low expression of placental TfR1 in women with preeclampsia.…”
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Swords and shields: the war between Candidatus Liberibacter asiaticus and citrus by Yanan Hu, Nannan Lu, Kaiqiang Bao, Shuting Liu, Ruimin Li, Ruimin Li, Ruimin Li, Guiyan Huang, Guiyan Huang, Guiyan Huang

“…In this review, we summarize recent advances in understanding the relationship between citrus and CLas, particularly examining the functions of Sec-dependent effectors (SDEs) and non-classically secreted proteins (ncSPs) in virulence, as well as their targeted interactions with citrus. …”
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Cytokine Reduction in the Treatment of Joint Conditions by J. D. Sipe, J. Martel-Pelletier, I. G. Otterness, J.-P. Pelletier

“…Potential agents for cytokine reduction include selective anti-cytokine antibodies, anticytokine receptor antibodies, cytokine receptor antagonist proteins, and soluble and chimeric cytokine receptor molecules. …”
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Effect of Nitrogen Source and Inorganic Phosphate Concentration on Methanol Utilization and PEX Genes Expression in Pichia pastoris by A. M. Rumjantsev, O. V. Bondareva, M. V. Padkina, E. V. Sambuk

“…Methylotrophic yeast Pichia pastoris has proved to be especially useful for production of various heterologous proteins. In biotechnology it is very important to maintain the balance between high levels of heterologous gene expression and cell viability. …”
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Therapeutic Potentials of Synapses after Traumatic Brain Injury: A Comprehensive Review by Zunjia Wen, Dong Li, Meifen Shen, Gang Chen

“…Second, we briefly describe several key synaptic proteins involved in neuroplasticity, which may be novel neuronal targets for specific intervention. …”
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Histone demethylases in autophagy and inflammation by Yaoyao Ma, Wenting Lv, Yi Guo, Tong Yin, Yujie Bai, Ziqi Liu, Chao Chen, WenjuanYang, Jiayi Feng, Wenbin Qian, Ruiling Tang, Yanting Su, Shigang Shan, Huifen Dong, Yongfen Bao, Lihua Qu

“…This article reviewed the function of KDMs proteins in autophagy and inflammation. Specifically, It focused on the specific regulatory mechanisms underlying the activation or inhibition of autophagy, as well as their abnormal expression in inflammatory responses. …”
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