TLR2 and TLR4 in the Brain Injury Caused by Cerebral Ischemia and Reperfusion by Ying Wang, Pengfei Ge, Yuhong Zhu

“…Toll-like receptors are a type of transmembrane proteins, which can recognize either exogenous pathogen-associated molecular patterns or endogenous stress or damage-associated molecular patterns in the innate immune system and initiate inflammatory responses. …”
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Protocol to study toxic, immune, and suicidal phenotypes of killer yeast by Rianne C. Prins, Sonja Billerbeck

“…Summary: Killer yeast produce antimicrobial proteins, often together with a self-protective immunity factor. …”
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RNA N6-Methyladenosine Modifications and the Immune Response by Ya-Nan Wang, Chen-Yang Yu, Hong-Zhong Jin

“…The discovery of binding proteins confirms that the m6A modification has a wide range of biological effects and significance at the molecular, cellular, and physiological levels. …”
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Spatiotemporal Regulators for Insulin-Stimulated GLUT4 Vesicle Exocytosis by Xiaoxu Zhou, Ping Shentu, Yingke Xu

“…Understanding the interaction between insulin signaling molecules and key regulatory proteins that are involved in spatiotemporal regulation of GLUT4 vesicle exocytosis is of great importance to explain the pathogenesis of diabetes and may provide new potential therapeutic targets.…”
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Facts About Riboflavin by R. Elaine Turner, Wendy J. Dahl

“…We need riboflavin to use the carbohydrates, fats, and proteins in the foods we eat. Riboflavin helps us use these nutrients for energy in our bodies and additionally functions as an antioxidant. …”
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Facts About Riboflavin by R. Elaine Turner, Wendy J. Dahl

“…We need riboflavin to use the carbohydrates, fats, and proteins in the foods we eat. Riboflavin helps us use these nutrients for energy in our bodies and additionally functions as an antioxidant. …”
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Inhibition of mmu_circ_0009303 improves metabolic dysfunction-associated steatotic liver disease by regulating lipid metabolism and oxidative stress by Ju Zhou, Wu Li, Xiaowei Chi, Dingchun Li, Chunxia Yang, Zhiwen Duan

“…Furthermore, mmu_circ_0009303 may be involved in regulating the expression of lipid metabolism-related regulatory proteins, such as CPT1A, SLC27A4, ACBD3, SREBP1, FAS, PPARα, and PPARγ. …”
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Identification and expression analysis of P-type ATPase IIIA subfamily in Puccinia Striiformis f. sp. tritici by Yingjie Sun, Hong Tao, Hong Han, Yiping Zou, Yingyu Xue, Shiwen Chen, Fei Tao

“…ATPases, a class of membrane proteins, play an important role in material exchange and signal transduction both within and outside biological cells by transporting ions and phospholipids. …”
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Draft genome dataset of Streptomyces griseoincarnatus strain R-35 isolated from tidal pool sedimentsMendeley DataNCBI by Danielle Dana Mitchell, Jo-Marie Vreulink, Alaric Prins, Marilize Le Roes-Hill

“…A total of 2570 hypothetical proteins were assigned, and 5246 proteins were assigned to function. …”
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The BET inhibitor JQ1 targets fat metabolism and counteracts obesity by Claudia Fornelli, Alessia Sofia Cento, Lorenzo Nevi, Raffaella Mastrocola, Gustavo Ferreira Alves, Giuseppina Caretti, Massimo Collino, Fabio Penna

“…Our previous data demonstrated the relevant role of the bromo and extra-terminal domain (BET) proteins inhibitor JQ1 in attenuating inflammation and fibrosis in sarcopenic mice. …”
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Reverse mutational scanning of SARS-CoV-2 spike BA.2.86 identifies epitopes contributing to immune escape from polyclonal sera by Najat Bdeir, Tatjana Lüddecke, Henrike Maaß, Stefan Schmelz, Ulfert Rand, Henning Jacobsen, Kristin Metzdorf, Upasana Kulkarni, Anne Cossmann, Metodi V. Stankov, Markus Hoffmann, Stefan Pöhlmann, Wulf Blankenfeldt, Alexandra Dopfer-Jablonka, Georg M. N. Behrens, Luka Čičin-Šain

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Proliferin-1 Ameliorates Cardiotoxin-Related Skeletal Muscle Repair in Mice by Hiroki Goto, Aiko Inoue, Limei Piao, Lina Hu, Zhe Huang, Xiangkun Meng, Yusuke Suzuki, Hiroyuki Umegaki, Masafumi Kuzuya, Xian Wu Cheng

“…In C2C12 myoblasts, rPLF-1 increased the levels of proteins for p-Akt, p-mTOR, p-GSK3α/β, p-Erk1/2, and p-p38MAPK as well as cellular functions; and these effects were diminished by the depletion of PLF-1 or silencing of its mannose-6-phosphate receptor. …”
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tPA‐GFP is a reliable probe for detecting compound exocytosis in human pancreatic β‐cells by Aishwarya A. Makam, Shruti Sharma, Prajwal Nagle, Nandhini M. Sundaram, Vidya Mangala Prasad, Nikhil R. Gandasi

“…Here, we used two cargo proteins (NPY and tPA) labeled with different fluorescent proteins (mCherry GFP and eGFP) and employed total internal reflection fluorescence microscopy (TIRF‐M) to capture distinct single‐granule and multi‐granular fusion events. …”
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The effect of conditioned media on the cellular proliferation of pancreatic cancer cells, pancreatic stellate cells, and myeloid-derived suppressor cells by Y. Chong, S. Samsudin, D. Bahrani, C. Chang, A. Masamune, S. Ng, N. Ismail, K. Ho

“…Its highly immunosuppressive tumour microenvironment is driven by secreted proteins, such as cytokines and growth factors, which promote the differentiation of immunosuppressive cells and influence cellular proliferation and migration. …”
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Long Noncoding RNA HCG9 Promotes Osteosarcoma Progression through RAD51 by Acting as a ceRNA of miR-34b-3p by Lu Wang, ShuangQing Li, Lin Qi, Lin Ling

“…Western blot was performed to detect the mitotic markers and apoptosis-related proteins. A nude mouse tumor formation experiment was used to evaluate osteosarcoma progression in vivo. …”
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Effects of linsitinib on M22 and IGF:1-treated 3D spheroids of human orbital fibroblasts by Fumihito Hikage, Megumi Suzuki, Tatsuya Sato, Araya Umetsu, Toshifumi Ogawa, Nami Nishikiori, Masato Furuhashi, Hiroshi Ohguro, Megumi Watanabe

“…The mRNA expression levels of several genes of ECM proteins and most of the other genes also fluctuated similarly to the changes in stiffness of 3D spheroids despite the fact that Lins induced up-regulation of inflammatory cytokines and MMP3. …”
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The MADS-Box Transcription Factor ClAG2 Is a Key Regulator for the Formation of Double Flower in <i>Clematis</i> L. by Xuerong Chen, Ping Zhou, Nanhong Guo, Yiping Zheng, Xiumei Hou, Lihui Zeng

“…Yeast two-hybrid assays demonstrated that ClAG2 could interact with class E proteins ClSEP3 and ClSEP4 but not with class B proteins ClAP3 and ClPI. …”
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Lentinan's effect on gut microbiota and inflammatory cytokines in 5-FU-induced mucositis mice by Xiaoxiao Zhang, Liang Wang, Asif Iqbal Khan, Ata Ur Rehman, Kavish Hasnain Khinsar, Yi Xin

“…Furthermore, increased expression of tight junction proteins (ZO-1, Claudin-1), mucin-2, and an increase in the number of goblet cells all confirmed our previous findings. …”
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Angesinenolide B, A Phthalide Dimeric Peroxide, Exerts Anti-Inflammatory Properties by Suppressing MAPK/STATs Signaling Pathways and ROS Production by Zhang L, Liu Y, Wang H, Guo S, Lv J

“…Moreover, the affinities between ASB and the target proteins were verified by molecular docking analysis. …”
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PPARs Mediate Lipid Signaling in Inflammation and Cancer by Liliane Michalik, Walter Wahli

“…PPARs, in turn, control the expression of networks of genes encoding proteins involved in all aspects of lipid metabolism. …”
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