Exploring the exoproteome of the parasitic nematode Anisakis simplex (s. s.) and its impact on the human host – an in vitro cross-talk proteomic approach by Robert Stryiński, Robert Stryiński, Ewa Fiedorowicz, Jesús Mateos, Aneta Andronowska, Elżbieta Łopieńska-Biernat, Mónica Carrera

“…While many studies have explored nematode biology and host interactions, the role of extracellular vesicles (EVs) as signaling molecules in parasitic nematodes is less understood.Materials and methodsTherefore, the proteins present in the EVs of A. simplex (s. s.) (Anis-EVs) were identified. …”
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Cancer Stem Cells from Tumor Cell Lines Activate the DNA Damage Response Pathway after Ionizing Radiation More Efficiently Than Noncancer Stem Cells by Heriberto Abraham Valencia-González, Graciela Ruíz, Elizabeth Ortiz-Sánchez, Alejandro García-Carrancá

“…We observed a higher baseline expression of activated response sensor proteins of DNA damage, such as ATM, H2A.X, and PARP1, in untreated CSC cultures. …”
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Perspectives on Structural, Physiological, Cellular, and Molecular Responses to Desiccation in Resurrection Plants by Yathisha Neeragunda Shivaraj, Plancot Barbara, Bruno Gugi, Maïté Vicré-Gibouin, Azeddine Driouich, Sharatchandra Ramasandra Govind, Akash Devaraja, Yogendra Kambalagere

“…Similarly, recent data show a major role of ABA, LEA proteins, and small regulatory RNA in regulating DT responses. …”
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FHIT Doubts are Clear Now by Anjilna Wali

“…Current research on the FHIT gene has depicted that Fhit interacts with different proteins through different pathways in the nucleus, mitochondria, and cytoplasm, directing the cell to apoptosis.…”
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Molecular Detection of Neuron-Specific ELAV-Like-Positive Cells in the Peripheral Blood of Patients with Small-Cell Lung Cancer by Vito D’Alessandro, Lucia Anna Muscarella, Massimiliano Copetti, Leopoldo Zelante, Massimo Carella, Gianluigi Vendemiale

“…Background: n-ELAV (neuronal-Embryonic Lethal, Abnormal Vision)-like genes belong to a family codifying for onconeural RNA-binding proteins. Anti-Hu-antibodies (anti-Hu-Ab) are typically associated with paraneoplastic encephalomyelitis/sensory neuropathy (PEM/PSN), and low titres of anti-Hu-Ab, were found in newly diagnosed Small Cell Lung Cancer (SCLC). …”
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Macrophage Extracellular Traps: Current Opinions and the State of Research regarding Various Diseases by Weizhen Weng, Zuoyu Hu, Yunfeng Pan

“…ETs are web-like structures that consist of proteins and DNA. ETs are thought to immobilize and kill microorganisms, as well as play an important role in tissue damage, inflammatory progression, and autoimmune diseases. …”
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Mitochondrial Dynamics: Functional Link with Apoptosis by Hidenori Otera, Katsuyoshi Mihara

“…The discovery of large GTPase family proteins that regulate mitochondrial dynamics, together with novel insights into the role of mitochondrial fusion and fission in apoptosis, has provided important clues to understanding the molecular mechanisms of cellular apoptosis. …”
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Antepartum Diagnosis and Management of Lamin A/C Disease by Nosheen Reza, Jessica L. Chowns, Amy Marzolf, Jessica Kim, Lisa D. Levine, Gregory Supple, Anjali Tiku Owens

“…Lamin A/C cardiac disease is a genetic cardiomyopathy and arrhythmia syndrome caused by alterations in the function of the nuclear lamin A and C proteins. It is inherited in an autosomal dominant manner and usually presents in mid- to late adulthood with atrioventricular conduction abnormalities, atrial and ventricular arrhythmias, biventricular dysfunction, and advanced heart failure. …”
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Yeast Methylotrophy: Metabolism, Gene Regulation and Peroxisome Homeostasis by Hiroya Yurimoto, Masahide Oku, Yasuyoshi Sakai

“…These features have made methylotrophic yeasts attractive hosts for the production of heterologous proteins and useful model organisms for the study of peroxisome biogenesis and degradation. …”
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Hepatocellular Bile Salt Transport: Lessons from Cholestasis by Michael Trauner, Peter Fickert, Rudolf E Stauber

“…With the increasing availability of molecular probes for these transporters, evidence now exists that decreased or even absent expression of hepatobiliary transport proteins in hepatocytes or cholangiocytes may explain impaired transport function that results in hyperbilirubinemia and cholestasis. …”
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Model of tumour angiogenesis -- analysis of stability with respect to delays by Marek Bodnar, Monika Joanna Piotrowska, Urszula Foryś, Ewa Nizińska

“…The model combines ideas of Hahnfeldt et al. (1999) and Agur et al. (2004) describing the dynamics of tumour, angiogenic proteins and effective vessels density. Presented analysis is focused on the dependance of the model dynamics on delays introduced to the system. …”
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Relationship of Autophagic Dysfunction With the Quality of Life and Sleep, Depression and Disease Severity in Patients With Restless Legs Syndrome by Esen Çiçekli, Hamza Malik Okuyan, Canan Birimoğlu Okuyan, Şeyda Öznur Ayçiçek, Dilcan Kotan

“…However, there is no study investigating the possible role of autophagy‐related proteins (ATGs) in RLS patients. Therefore, we aimed to investigate the expression and diagnostic potential of ATG3 and ATG5, as well as the relationships between these proteins and laboratory markers, depression, disease score, quality of life, and sleep in RLS patients. …”
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Genome-wide identification and expression analysis of the PIN gene family in the pepper pedicel abscission zone and during root development by HE Lei, YAN Xi, LAI Wei, LIU Chongzheng, YANG Hong, HE Jianwen

“…Most of these proteins are stable. Additionally, significant collinearity was observed among the CaPINs, indicating a close genetic relationship with the tomato genome. …”
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Medium Time Heating of Syrop from Red Betel Leaf (Piper crocatum ruiz pav) Can Reduce Carcinoembryonic Antigen (CEA) Level Among Adult Women in Southeast Sulawesi, Indonesia by Hariani Hariani, Wiralis Wiralis, Teguh Faturrahman Teguh Faturrahman, Suwarni Suwarni

“…Red betel leaves have been shown to induce apoptosis in breast cancer cells (MCF-7), activate pro-apoptotic proteins (Bax), and inhibit anti-apoptotic proteins (Bcl-2). …”
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Cobalt-induced oxidative stress and defense responses of Adhatoda vasica proliferated shoots by Abeer A. Radi, Fatma A. Farghaly, Fatma A. Al-Kahtany, Ahmed M. Zaher, Afaf M. Hamada

“…The analysis revealed variations in the peaks associated with major macromolecules, including phenolic compounds, lipids, proteins, carbohydrates, cellulose, hemicellulose, and sugars. …”
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Sustainability and livestock: a doable combination by Antonella Chiariotti

“…Rapid urbanization, increased purchasing power, and dietary change drive demand for richer diets and animal-origin proteins, leaving more than 868 million undernourished citizens worldwide and 850 million living in developing countries. …”
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Proteomics and transcriptomics combined reveal specific immunological markers in autoimmune thyroid disease by Xia Chen, Hui Chen

“…Enrichment analysis revealed that these differentially expressed genes and proteins are primarily associated with immune function, antigen-antibody binding, and alterations in immune cells. …”
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Modern classification and molecular-genetic aspects of osteogenesis imperfecta by A. R. Zaripova, R. I. Khusainova

“…In the last decade, it has become  known that autosomal recessive, autosomal dominant and X-linked mutations in a wide range of genes, encoding  proteins that are involved in the synthesis of type I collagen, its processing, secretion and post-translational modification, as well as in proteins that regulate the differentiation and activity of bone-forming cells, cause imperfect  osteogenesis. …”
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High Expression of Ten Eleven Translocation 1 Is Associated with Poor Prognosis in Hepatocellular Carcinoma by Haopeng Wen, Tengfei Ji, Liteng Lin, Nan Cheng, Kangshun Zhu, Liangqi Cao

“…However, the effect of DNA demethylation enzymes, ten eleven translocation (TET) proteins, has not been comprehensively characterized in liver cancer. …”
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Identifying MTHFD1 and LGALS4 as Potential Therapeutic Targets in Prostate Cancer Through Multi-Omics Mendelian Randomization Analysis by Huan Han, Hanwen Su, Zhihua Lv, Chengliang Zhu, Jingtao Huang

“…However, future experiments are warranted to assess the utility and effectiveness of these candidate proteins.…”
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