Immunomodulatory Properties of HLA-G in Infectious Diseases by Laurence Amiot, Nicolas Vu, Michel Samson

“…The polymorphism, the interference of viral proteins with HLA-G intracellular trafficking, and various cytokines have been described to modulate HLA-G expression during infections. …”
Get full text

Molluscan Shell Matrix Characterization by Preparative SDS-PAGE by Frederic Marin

“…We describe a protocol that overcomes this difficulty and permits collection of a large amount of shell proteins for further in vitro characterization. After dissolution of the mineral phase, the glycoproteins are fractionated �blind� on a preparative electrophoresis. …”
Get full text

2′-Hydroxycinnamaldehyde induces ROS-mediated apoptosis in cancer cells by targeting PRX1 and PRX2 by Yae Jin Yoon, Yu-Jin Lee, Jiyeon Choi, Seung-Wook Chi, Sangku Lee, Kyung Chan Park, Byoung-Mog Kwon, Dong Cho Han

“…These findings demonstrate that PRX1 and PRX2 are molecular target proteins responsible for HCA-induced ROS elevation and cancer cell death.…”
Get full text

Hydrogen Sulfide Promotes Functional Endometrium Recovery via Regulating Pyroptosis in Severe Endometrial Injury: A Prospective Laboratory Based Randomized Control Trial by Haiyan Shan, Mingyuan Xu, Jie Ni, Ling Zhou, Mengchun Xue, Jun Xue, Xiaohuan Yuan, Luyang Tao, Mingyang Zhang, Hong Zhang

“…Pyroptosis, a form of programmed cell death associated with inflammation, is initiated by the cleavage of gasdermin family proteins by caspase, which has been implicated in endometrial injury. …”
Get full text

Molecular dynamics simulation based prediction of T-cell epitopes for the production of effector molecules for liver cancer immunotherapy. by Sidra Zafar, Yuhe Bai, Syed Aun Muhammad, Jinlei Guo, Haris Khurram, Saba Zafar, Iraj Muqaddas, Rehan Sadiq Shaikh, Baogang Bai

“…Antigenicity, molecular weight, subcellular localization and expression site predictions were used to shortlist liver cancer associated proteins including AMBP, CFB, CDHR5, VTN, APOBR, AFP, SERPINA1 and APOE. …”
Get full text

The role of circadian rhythm regulator PERs in oxidative stress, immunity, and cancer development by Baimei Zhao, Eugenie Nepovimova, Qinghua Wu

“…At the heart of this interaction lies the PERIOD proteins (PERs), pivotal to the circadian clock, influencing the timing of physiological and behavioral processes and impacting oxidative stress, immune functionality, and tumorigenesis. …”
Get full text

<italic>Hedyotis Diffusa</italic> Willd Increase Drugs Accumulation by Regulating Hedgehog Pathway in Drug Resistant Colorectal Cancer Cells by Yiyi JIN, Qiongyu LI, Zijun LAI, Zhaokun YAN, Jianyu FENG, Jiumao LIN

“…Western Blot was used to determine the expression of multidrug resistance (MDR) related proteins, such as MRP1, P-gp, LRP, BCRP, and the core proteins of HH signaling pathway, including SHH, SMO, SUFU and Gli-1.Results:After treated with different concentration of EEHDW, proliferation of HCT-8/5-FU cells were inhibited in a dose dependent (<italic>P</italic>&lt;0.01). …”
Get full text

Development of water-soluble zein colloid particles and in situ antibacterial evaluation by multiple headspace extraction gas chromatography by Yan Yin, Fuzhen Zhou, Yechong Yin, Yonghong Peng

Get full text

Silencing RNA for MMPs May Be Utilized for Cardioprotection by Marta Banaszkiewicz, Anna Krzywonos-Zawadzka, Agnieszka Olejnik, Agnieszka Noszczyk-Nowak, Iwona Bil-Lula

“…Ischemia/reperfusion (I/R) injury is accompanied by an increase of matrix metalloproteinase 2 (MMP-2) activity, which degrades heart contractile proteins. The aim of the study was to investigate the effect of MMP-2 small interfering RNA (MMP-2 siRNA) administration on I/R heart. …”
Get full text

Optically driven microtools with an antibody‐immobilised surface for on‐site cell assembly by Shuntaro Mori, Takumi Ito, Hidekuni Takao, Fusao Shimokawa, Kyohei Terao

“…The microtool containing antibodies for CD51/61 and CD44 proteins was manipulated using optical tweezers to capture HeLa cells placed on a microfluidic device. …”
Get full text

Identification of Allergenic Tropomyosins with Known and Unknown Sequences in Seafood Products by Marta Godlewska, Piotr Minkiewicz, Małgorzata Darewicz, Anna Iwaniak

“…Several peptides likely to be released during proteolysis can be found in many sequences of proteins from this family. The aim of the present study was to evaluate the possibility of identifying tropomyosins with known and unknown amino acid sequences in unheated, boiled and fried seafoods. …”
Get full text

The Impact of Autophagy on Cell Death Modalities by Stefan W. Ryter, Kenji Mizumura, Augustine M. K. Choi

“…Autophagy represents a homeostatic cellular mechanism for the turnover of organelles and proteins, through a lysosome-dependent degradation pathway. …”
Get full text

Adenocarcinoma with Neuroendocrine Differentiation of the Colon Accompanying Osteoclast-Like Giant Cells by Mitsuhiro Tachibana, Tadahiro Isono, Yutaka Tsutsumi

“…Deficient expression of DNA mismatch repair (dMMR) proteins was immunohistochemically confirmed. The patient died 16 months after surgery. …”
Get full text

Uncovering the Phytochemical Profile, Antioxidant Potency, Anti-Inflammatory Effects, and Thrombolytic Activity in Dendrobium lindleyi Steud. by Minhajur Rahman, Roxy Begum, Abu Taleb Surag, Md. Shakhuat Hossain Tusher, Mohammed Kamrul Huda

“…The qualitative screening found a variety of bioactive compounds, including alkaloids, coumarins, cardiac glycosides, glycosides, flavonoids, proteins, phenols, quinines, resins, steroids, saponins, tannins, and terpenoids, in varying amounts. …”
Get full text

Caveolin-Mediated Endocytosis: Bacterial Pathogen Exploitation and Host–Pathogen Interaction by Dibyasri Barman, Rishi Drolia

“…Caveolin proteins facilitate the creation of caveolae and have three members in vertebrates: caveolin-1, caveolin-2, and caveolin-3. …”
Get full text

G1 Cell Cycle Arrest Is Induced by the Fourth Extracellular Loop of Meningococcal PorA in Epithelial and Endothelial Cells by Matthew Vassey, Rininta Firdaus, Akhmed Aslam, Lee M. Wheldon, Neil J. Oldfield, Dlawer A. A. Ala’Aldeen, Karl G. Wooldridge

“…The meningococcal surface proteins PorA and PilQ were identified as ligands for this receptor. …”
Get full text

Dietary Patterns among Eight Grade Adolescents and their Impact on Dietary Adequacy by Zeida Bárbara Alejo, Amarelis Rodríguez Fuente, Daysi López Sosa, Pilar Almaguer Sabina

“…The major concerning points are the low energy intake and the fact that it is mainly based on carbohydrates, while the deficit in proteins intake, iron and fat has reached a critical point in more than half of our patients.…”
Get full text

The Regulation of the CNS Innate Immune Response Is Vital for the Restoration of Tissue Homeostasis (Repair) after Acute Brain Injury: A Brief Review by M. R. Griffiths, P. Gasque, J. W. Neal

“…Serpins also expressed by glia counter the neurotoxic effects of thrombin and other systemic proteins that gain entry to the CNS following injury. …”
Get full text

Aspects of improving metrological characteristics of a sensor based on palladium nanoparticles for methionine determination by Eduard V. Gorchakov, Darya O. Perevezentseva, Elena A. Vaitulevich, Oksana V. Dubinina

“…This amino acid serves as a precursor for the biosynthesis of proteins and peptides, as well as a donor of methyl groups, making it an essential participant in numerous biochemical processes, including cysteine synthesis. …”
Get full text

Dual RNA-seq reveals transcriptome changes during Fusarium virguliforme-Trichoderma afroharzianum interactions. by Mirian F Pimentel, Leonardo F Rocha, Arjun Subedi, Jason P Bond, Ahmad M Fakhoury

“…Several differentially expressed genes-encoding secreted proteins, including CAZymes and CBM1-domain-containing proteins, were up-regulated in Th19A and Th4 upon interaction with the pathogen, even before physical contact, demonstrating possible volatile-mediated recognition of both isolates by F. virguliforme. …”
Get full text