Effects of Exercise Preconditioning Mediating Oxidative Stress to Regulate PI3K/Akt and Nrf2/HO-1 Pathways to Alleviate Cognitive and Learning Disorders in Rats by KONG Haijun, LI Xinlong, WANG Fenghua, CHEN Xiaoan

“…The relative expressions of Nox1, Duox2 and GCLM proteins in hippocampus significantly increased (<italic>P</italic>&lt;0.05), while the ratios of p-PI3K/PI3K, p-Akt/Akt, p-GSK-3β/GSK-3β and the relative expressions of Nrf2 and HO-1 proteins significantly decreased (<italic>P</italic>&lt;0.05). …”
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WNT-Pathway Activation in IBD-Associated Colorectal Carcinogenesis: Potential Biomarkers for Colonic Surveillance by Marian M. H. Claessen, Marguerite E. I. Schipper, Bas Oldenburg, Peter D. Siersema, G. Johan A. Offerhaus, Frank P. Vleggaar

“…The expression of Wnt-signaling proteins and p53 during colitis-associated carcinogenesis was determined.…”
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The Emerging Role of Rab5 in Membrane Receptor Trafficking and Signaling Pathways by Wanqiong Yuan, Chunli Song

“…Ras analog in brain (Rab) proteins are small guanosine triphosphatases (GTPases) that belong to the Ras-like GTPase superfamily, and they can regulate vesicle trafficking. …”
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Two-Component Signal Transduction System SaeRS Positively Regulates Staphylococcus epidermidis Glucose Metabolism by Qiang Lou, Yijun Qi, Yuanfang Ma, Di Qu

“…The downregulated proteins included enzymes related to glycolysis and TCA cycle, suggesting that glucose is not properly utilized in S. epidermidis when saeRS was deleted. …”
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Applications of Recombinant Dna Technology in Gastrointestinal Medicine and Hepatology: Basic Paradigms of Molecular Cell Biology. Part B: Eukaryotic Gene Transcription and Post-Tr... by Gary E Wild, Patrizia Papalia, Mark J Ropeleski, Julio Faria, Alan BR Thomson

“…The production of each mRNA in human cells involves complex interactions of proteins (ie, trans-acting factors) with specific sequences on the DNA (ie, cis-acting elements). …”
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The Impact of Advanced Glycation End-Products (AGEs) on Proliferation and Apoptosis of Primary Stem Cells: A Systematic Review by Lize Evens, Hanne Beliën, Dorien Deluyker, Annelies Bronckaers, Pascal Gervois, Marc Hendrikx, Virginie Bito

“…AGEs are a heterogeneous group of glycated products, nonenzymatically formed when proteins and/or lipids become glycated and oxidized. …”
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MMP-2 and MMP-9 Activities and TIMP-1 and TIMP-2 Expression in the Prostatic Tissue of Two Ethanol-Preferring Rat Models by Beatriz Aparecida Fioruci-Fontanelli, Luiz Gustavo A. Chuffa, Leonardo O. Mendes, Patricia Fernanda F. Pinheiro, Flávia Karina Delella, Cilmery S. Kurokawa, Sérgio Luis Felisbino, Francisco Eduardo Martinez

“…Dorsal prostatic lobe was less affected showing no significant alterations in these proteins, except for a reduction in the TIMP-1 expression in UChA rats. …”
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Research Progress on Alleviatory Effects of 6-Gingerol and 6-Shogaol on Intestine Tight Junction Damage by LI Yu, OUYANG Fangxin, ZHANG He, WANG Wenyu, DONG Jingxiao, LI Dapeng, LI Feng

“…The intestinal barrier plays a key role in preventing harmful substance invasions and maintaining intestinal homeostasis, with tight junction proteins being essential for maintaining the integrity of the intestinal barrier. …”
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A Study of Epstein-Barr Virus BRLF1 Activity in a Drosophila Model System by Amy Adamson, Dennis LaJeunesse

“…We have created Drosophila model systems to study the interactions between host cellular proteins and the Epstein-Barr virus (EBV) immediate-early genes BRLF1 and BZLF1. …”
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Impact of Combined Acidic and Hyperosmotic Shock Conditions on the Proteome of Listeria monocytogenes ATCC 19115 in a Time-Course Study by Dong Lai Zhang, Ya Long Bai, John P. Bowman

“…From the iTRAQ results, the proteome level changes that occur rapidly during the inactivation process mainly affected prophage, cell defense/detoxification, carbohydrate-related metabolism, transporter proteins, phosphotransferase systems, cell wall biogenesis, and specific cell surface proteins. …”
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Gastric Precancerous Lesions: From Progenitor Cell and Microsatellite Instability to Clinical Interpretation of Gastric Cancer Risk by A. V. Kononov, V. A. Rubtsov, M. N. Parygina, A. G. Shimanskaya, S. I. Mozgovoi, E. G. Pomorgailo, M. V. Markelova, Yu. A. Fedotova

“…MMR-deficient cases were found in low (2.8 %) and high-grade (2.8 %) dysplasia with the immunohistochemical evaluation of MMR-system proteins in gastric mucosa specimens. In all indefinite for dysplasia cases MMR-system proteins remained unaffected. …”
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Impact of Varicocele on The Expression of Testicular Enzymes Involved in The Transsulfuration Pathway by Azam Shiasi, Marziyeh Tavalaee, Ramesh Monajemi, Dattilo M, Mohammad Hossein Nasr-Esfahani

“…We evaluated sperm parameters and functional tests,as well as the expression of CBS, CSE, and HO-1 proteins using Western blot analysis. Serum levels of methionine,homocysteine, and taurine were analyzed through high-performance liquid chromatography, while vitamin B6concentrations were measured using enzyme-linked immunosorbent assay. …”
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RHOBTB2 Variant p.Arg511Gln Causes Developmental and Epileptic Encephalopathy Type 64 in an Infant: A Case Report and Hotspot Variant Analysis by Qian Liu, Feifei Li, Qin Ruan, Nana Wang, Zhengjun Fan

“…We used Discovery Studio software to analyze the folding free energy of variant proteins, and the AlphaFold database to analyze structural alterations in mutant proteins. …”
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Polymorphism of CLE gene sequences in potato by M. S. Gancheva, M. R. Losev, A. A. Gurina, L. O. Poliushkevich, I. E. Dodueva, L. A. Lutova

“…We also found examples of polymorphism of domains of CLE proteins that carried different functions. Further study of potato CLE proteins will reveal their role in development, including regulation of productivity in this important agricultural crop.…”
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Molecular-genetic mechanisms of the interaction between processes of cell response to mechanical stress and neuronal apoptosis in primary open-angle glaucoma by O. V. Saik, N. A. Konovalova, P. S. Demenkov, N. V. Ivanisenko, T. V. Ivanisenko, D. E. Ivanoshchuk, O. S. Konovalova, O. A. Podkolodnaya, I. N. Lavrik, N. A. Kolchanov, V. A. Ivanisenko

“…Currently, there is a large number of scientific publications describing proteins and genes involved in the pathogenesis of POAG, including neuronal apoptosis and the cell response to mechanical stress. …”
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The SERPINB4 gene mutation identified in twin patients with Crohn’s disease impaires the intestinal epithelial cell functions by Xiao-Mei Ouyang, Jun-Hui Lin, Ying Lin, Xian-Ling Zhao, Ya‐Ni Huo, Lai-Ying Liang, Yong-Dong Huang, Gui-Jing Xie, Peng Mi, Zhen-Yu Ye, Bayasi Guleng

“…Transcriptome sequencing revealed that the expression of genes encoding proinflammatory proteins (IL1B, IL6, IL17, IL24, CCL2, and CXCR2) and key proteins in the immune response (S100A9, MMP3, and MYC) was significantly upregulated during SERPINB4 mutant-induced apoptosis. …”
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Electrophysiology-based screening identifies neuronal HtrA serine peptidase 2 (HTRA2) as a synaptic plasticity regulator participating in tauopathy by Naizhen Zheng, Kun Li, Jing Cao, Zijie Wang, Liang Zhang, Zihao Zhao, Jiawei He, Yong Wang, Xiang Zhu, Yiqing Chen, Jian Meng, Dongdong Zhao, Mengxi Niu, Hong Luo, Xian Zhang, Hao Sun, Yun-wu Zhang

“…We identified 20 differentially expressed proteins (DEPs) shared by the LTP and the LTD processes. …”
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NLS-binding deficient Kapβ2 reduces neurotoxicity via selective interaction with C9orf72-ALS/FTD dipeptide repeats by Kevin M. Kim, Amandeep Girdhar, Maria E. Cicardi, Vaishnavi Kankate, Miyuki Hayashi, Ruoyu Yang, Jenny L. Carey, Charlotte M. Fare, James Shorter, Gino Cingolani, Davide Trotti, Lin Guo

“…Abstract Arginine-rich dipeptide repeat proteins (R-DPRs) are highly toxic proteins found in patients with C9orf72-linked amyotrophic lateral sclerosis and frontotemporal dementia (C9-ALS/FTD). …”
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Impact of eggshell membrane on metabolism and cell adhesion in oxidatively stressed canine chondrocytes by Juraj Vozar, Nikola Hudakova, Natalia Nosalova, Mykhailo Huniadi, Dana Marcincakova, Slavomir Hornak, Lubica Hornakova, Petra Majerova, Dasa Cizkova, Dasa Cizkova

“…Eggshell membrane (ESM) is a rich source of bioactive compounds, including proteins, peptides, and antioxidants, contributing to its potential therapeutic benefits. …”
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Proteomic Analysis of Hypoxia-Induced Senescence of Human Bone Marrow Mesenchymal Stem Cells by Liping Mai, Guodong He, Jing Chen, Jiening Zhu, Shaoxian Chen, Xinghua Hou, Hui Yang, Mengzhen Zhang, Yueheng Wu, Qiuxiong Lin, Min Yang, Xiaohong Li

“…TMT analysis of 12-hour hypoxia-induced cells identified over 6000 proteins, including 686 differentially expressed proteins. …”
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