Formation mechanisms of ethyl acetate and organic acids in Kluyveromyces marxianus L1-1 in Chinese acid rice soup by Na Liu, Likang Qin, Laili Hu, Song Miao

“…At least 4231 genes and 2937 proteins were identified and 610 differentially expressed proteins were annotated to 30 Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways based on the analysis results of transcriptome and proteome. …”
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The Role of Hepatic Expression of STAT1, SOCS3 and PIAS1 in the Response of Chronic Hepatitis C Patients to Therapy by Sherif El-Saadany, Dina H Ziada, Hanan El Bassat, Wael Farrag, Hesham El-Serogy, Manal Eid, Manal Abdallah, Medhat Ghazy, Hoda A Salem

“…Signal transducers and activators of transcription (STAT) proteins play a critical role in antiviral defense.…”
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Autophagy in Inflammatory Diseases by Alexander J. S. Choi, Stefan W. Ryter

“…Autophagy provides a mechanism for the turnover of cellular organelles and proteins through a lysosome-dependent degradation pathway. …”
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Molecular Mechanisms in Exercise-Induced Cardioprotection by Saeid Golbidi, Ismail Laher

“…A partial list of proposed mechanisms for exercise-induced cardioprotection include induction of heat shock proteins, increase in cardiac antioxidant capacity, expression of endoplasmic reticulum stress proteins, anatomical and physiological changes in the coronary arteries, changes in nitric oxide production, adaptational changes in cardiac mitochondria, increased autophagy, and improved function of sarcolemmal and/or mitochondrial ATP-sensitive potassium channels. …”
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Emerging Roles of Synapse Organizers in the Regulation of Critical Periods by Adema Ribic, Thomas Biederer

“…Attractive candidates are pre- and postsynaptic transmembrane proteins that form adhesive complexes across the synaptic cleft. …”
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Prediction of ADMET profile and anti-inflammatory potential of chamuangone by Sompot Jantarawong, Puripat Wathanaphanit, Pharkphoom Panichayupakaranant, Yutthana Pengjam

“…The present findings suggest that chamuangone has favorable ADMET properties, interacts strongly with major proteins involved in inflammation, and exhibits anti-inflammatory activity in LPS-induced macrophages, making it a promising anti-inflammatory agent.…”
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The Spectrum of Anti-Chromatin/Nucleosome Autoantibodies: Independent and Interdependent Biomarkers of Disease by Sonal Mehra, Marvin J. Fritzler

“…More recently, interest has focussed on other components of chromatin such as high mobility group (HMG) proteins both as targets of B cell responses and pro-inflammatory mediators. …”
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Computational Evaluation of Tridax Procumbens Phytoconstituents in Wound Healing Process by M. Jeevitha, Kaarthikeyan Gurumoorthy, M. Navarasu

“…Results of this study showed that all the four compounds showed interaction with selected target proteins. Among the four compounds, Tannic acid showed excellent binding and hydrogen bond interaction with all the selected target proteins. …”
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Exercise and the Cardiovascular System by Saeid Golbidi, Ismail Laher

“…We also discuss the roles of boosting antioxidant levels, consequences of epicardial fat reduction, increases in expression of heat shock proteins and endoplasmic reticulum stress proteins, mitochondrial adaptation, and the role of sarcolemmal and mitochondrial potassium channels in the contributing to the cardioprotection offered by exercise. …”
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The Role of Deubiquitinating Enzymes in Synaptic Function and Nervous System Diseases by Jennifer R. Kowalski, Peter Juo

“…Posttranslational modification of proteins by ubiquitin has emerged as a critical regulator of synapse development and function. …”
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Co-Localized in Amyloid Plaques Cathepsin B as a Source of Peptide Analogs Potential Drug Candidates for Alzheimer’s Disease by Marilena K. Theodoropoulou, Konstantina D. Vraila, Nikos C. Papandreou, Georgia I. Nasi, Vassiliki A. Iconomidou

“…Interestingly, besides A<i>β</i>, other proteins are co-localized within amyloid plaques. Peptide analogs corresponding to the “aggregation-prone” regions (APRs) of these proteins could exhibit high-affinity binding to A<i>β</i> and significant inhibitory potential against the A<i>β</i> oligomerization process. …”
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Characterization of the procoagulant phenotype of amniotic fluid across gestation in rhesus macaques and humans by Chih Jen Yang, Lyndsey E. Shorey-Kendrick, Cristina Puy, Ashley E. Benson, Phillip A. Wilmarth, Ashok P. Reddy, Keith D. Zientek, Kilsun Kim, Adam Crosland, Chaevien S. Clendinen, Lisa M. Bramer, Olivia L. Hagen, Helen H. Vu, Joseph E. Aslan, Owen J.T. McCarty, Joseph J. Shatzel, Brian P. Scottoline, Jamie O. Lo

“…Conclusion: Overall, our findings reveal that the addition of AF to plasma enhances coagulation in a manner dependent on phospholipids as well as the presence of proteases and other proteins that directly regulate coagulation. We describe a correlation between clotting time and expression of coagulation proteins and phosphatidylserine in both rhesus and human AF, supporting the use of rhesus models for future studies of AF biology.…”
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Comparative functional analysis of a new CDR1-like ABC transporter gene in multidrug resistance and virulence between Magnaporthe oryzae and Trichophyton mentagrophytes by Jing Wang, Chenwen Xiao, Shuang Liang, Muhammad Noman, Yingying Cai, Zhen Zhang, Xueming Zhu, Rongyao Chai, Haiping Qiu, Zhongna Hao, Yanli Wang, Jiaoyu Wang, Guolian Bao, Guochang Sun, Fucheng Lin

“…ABC transporters play pivotal roles in multidrug resistance in fungi, with some ABC proteins indispensable for the pathogenicity of plant fungal pathogens. …”
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Targeting the Fanconi Anemia Pathway to Identify Tailored Anticancer Therapeutics by Chelsea Jenkins, Jenny Kan, Maureen E. Hoatlin

“…The Fanconi Anemia (FA) pathway consists of proteins involved in repairing DNA damage, including interstrand cross-links (ICLs). …”
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Long non-coding RNA linc00152 acting as a promising oncogene in cancer progression by Danbi Seo, Dain Kim, Wanyeon Kim

“…Accumulated evidence indicates that the long non-coding RNAs (lncRNAs), which are transcribed but not translated into functional proteins, contribute to cancer development. Recently, linc00152 (an lncRNA) was identified as a potent oncogene in various cancer types, and shown to be involved in cancer cell proliferation, invasiveness, and motility by sponging tumor-suppressive microRNAs acting as a competing endogenous RNA, binding to gene promoters acting as a transcriptional regulator, and binding to functional proteins. …”
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Mitochondrial Dysfunction in Parkinson's Disease by P. C. Keane, M. Kurzawa, P. G. Blain, C. M. Morris

“…A number of genes that have been shown to have links with inherited forms of PD encode mitochondrial proteins or proteins implicated in mitochondrial dysfunction, supporting the central involvement of mitochondria in PD. …”
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Cytokine and Growth Factor Activation In Vivo and In Vitro after Spinal Cord Injury by Elisa Garcia, Jorge Aguilar-Cevallos, Raul Silva-Garcia, Antonio Ibarra

“…These events are mediated by the upregulation of genes with roles in inflammation, transcription, and signaling proteins. In particular, cytokines and growth factors are signaling proteins that have important roles in the pathophysiology of SCI. …”
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Polarity and migration of cranial and cardiac neural crest cells: underlying molecular mechanisms and disease implications by Esteban Salinas, Esteban Salinas, Francis Ruano-Rivadeneira, Juan Ignacio Leal, Teresa Caprile, Marcela Torrejón, Cecilia Arriagada, Cecilia Arriagada

“…The main cellular mechanisms that sustain this migration include contact inhibition of locomotion, co-attraction, chemotaxis and mechanical cues from the surrounding environment, all regulated by proteins that orchestrate cell polarity and motility. …”
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Assessment of the Accelerated Shelf Life of Human Milk Dehydrated by Aspersion and Treated by UV, High Pressures, and Pasteurization by B. R. Aguilar Uscanga, J. R. Solís Pacheco, J. A. Ragazzo-Sánchez, A. Cavazos Garduño, J. C. Muro Valdéz, A. Rodríguez Arreola, J. C. Serrano Niño

“…Effectiveness of packaging, microbiological viability, and deterioration of carbohydrates, lipids, and proteins was evaluated. The results showed that proteins and carbohydrates in powdered human milk with different treatments did not show significant changes during storage at 25 to 40°C and without the growth of microorganisms. …”
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p130 And pRb in the Maintenance of Transient Quiescence of Mesenchymal Stem Cells by Boris Popov, Nikolai Petrov, Vladimir Ryabov, Igor Evsyukov

“…The state of quiescence is being controlled by the pRb family proteins which show overlapping functions in cell cycle regulation; however, their roles in controlling the proliferation of mesenchymal stem cells (MSCs) remain to be understood. …”
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