Toll-Like Receptor Signaling Pathways—Therapeutic Opportunities by Jiankun Zhu, Chandra Mohan

“…Toll-like receptors (TLRs) are transmembrane proteins acting mainly as sensors of microbial components. …”
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Evaluating the Role of Wnt Signal Transduction in Promoting the Development of the Heart by Leonard M. Eisenberg, Carol A. Eisenberg

“…Wnts are a family of secreted signaling proteins that are encoded by 19 distinct genes in the vertebrate genome. …”
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Lathyrol affects the expression of AR and PSA and inhibits the malignant behavior of RCC cells by Song Shengyou, Tai Lunwei, Zhou Lei, Jiang Junling, Zhao Junfeng

“…To investigate how lathyrol affects aggressive behaviors and related proteins of the androgen receptor (AR) 786-O cells.…”
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Evolution of the umbilical cord blood proteome across gestational development by Leena B. Mithal, Nicola Lancki, Ted Ling-Hu, Young Ah Goo, Sebastian Otero, Nathaniel J. Rhodes, Byoung-Kyu Cho, William A. Grobman, Judd F. Hultquist, Denise Scholtens, Karen K. Mestan, Patrick C. Seed

“…In later gestations, proteins with increased abundance are in immune response and inflammatory pathways, including complements and calcium-binding proteins. …”
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A Helminth-Derived Chitinase Structurally Similar to Mammalian Chitinase Displays Immunomodulatory Properties in Inflammatory Lung Disease by Friederike Ebner, Katja Lindner, Katharina Janek, Agathe Niewienda, Piotr H. Malecki, Manfred S. Weiss, Tara E. Sutherland, Arnd Heuser, Anja A. Kühl, Jürgen Zentek, Andreas Hofmann, Susanne Hartmann

“…Here, we aimed to identify the proteins accounting for the modulatory effects of the T. suis L1 ES proteins and studied six selected T. suis L1 proteins for their immunomodulatory efficacy in a murine OVA-induced allergic airway disease model. …”
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Gender Differences in Pulmonary Function, Respiratory Symptoms, and Macrophage Proteomics among HIV-Infected Smokers by Shiva D. Rahmanian, Karen L. Wood, Shili Lin, Mark A. King, April Horne, Shangbin Yang, Haifeng M. Wu, Philip T. Diaz

“…Proteomic analysis revealed 29 proteins with at least a 2-fold higher expression in males and 13 identified proteins that were higher in females. …”
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Examination of the Anaerobic Growth of Campylobacter concisus Strains by Hoyul Lee, Rena Ma, Michael C. Grimm, Stephen M. Riordan, Ruiting Lan, Ling Zhong, Mark Raftery, Li Zhang

“…An oral C. concisus strain was found to express a number of putative virulence proteins and the expression levels of these proteins were not affected by H2. …”
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Role of calpain system in meat tenderness: A review by Z.F. Bhat, James D. Morton, Susan L. Mason, Alaa El-Din A. Bekhit

“…They are known to be involved in the proteolysis of functionally relevant structural proteins such as the myofibrillar proteins and cytoskeletal anchorage complexes. …”
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Cordycepin Protects against Hepatic Ischemia/Reperfusion Injury via Inhibiting MAPK/NF-κB Pathway by Jiameng Ding, null WenjuanYang, Yuhui Jiang, Jie Ji, Jie Zhang, Liwei Wu, Jiao Feng, Yuanyuan Zheng, Yan Li, Ziqi Cheng, Qiang Yu, Jianye Wu, Jingjing Li, Kan Chen, Chuanyong Guo

“…Notably, cordycepin attenuated the inflammatory response and the production of proapoptosis proteins, while increasing expression of antiapoptosis proteins and decreasing expression of autophagy-linked proteins. …”
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Formation, Contraction, and Mechanotransduction of Myofribrils in Cardiac Development: Clues from Genetics by Javier T. Granados-Riveron, J. David Brook

“…Recently, mutations in genes encoding myofibrillar proteins expressed in the embryonic heart have also emerged as an important genetic causative factor of the disease, which implies that the contraction of the early heart primordium contributes to its morphogenesis. …”
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The Genetic Perspective of Familial Glucocorticoid Deficiency: In Silico Analysis of Two Novel Variants by Katayoun Heshmatzad, Nejat Mahdieh, Ali Rabbani, Abdolah Didban, Bahareh Rabbani

“…Four mutations were responsible for half of patients. 39 homozygous patients had MRAP mutations; 14 variants were determined in the MRAP gene. Nine proteins were predicted by STRING to associate with the studied proteins. …”
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The triterpenoid curcumene mediates the relative hydrophilicity of Bacillus subtilis spores by Stefany Castaldi, Giuliana Donadio, Ivana Staiano, Ezio Ricca, Rachele Isticato

“…ABSTRACT Spores of Bacillus subtilis are surrounded and protected by the coat and the crust, multi-layered structures mainly made of proteins and polysaccharides. These polysaccharides are covalently linked to some of the coat and crust proteins and influence some spore properties, such as surface adhesion and hydrophilicity. …”
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Recovery of the Cell Cycle Inhibition in CCl4-Induced Cirrhosis by the Adenosine Derivative IFC-305 by Victoria Chagoya de Sánchez, Lidia Martínez-Pérez, Rolando Hernández-Muñoz, Gabriela Velasco-Loyden

“…Diminution and small changes were observed in the studied proteins in the cirrhotic animals without treatment. …”
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PfFBXO1 is essential for inner membrane complex formation in Plasmodium falciparum during both asexual and transmission stages by Sreelakshmi K. Sreenivasamurthy, Carlos Gustavo Baptista, Christopher M. West, Ira J. Blader, Jeffrey D. Dvorin

“…Proteomic analysis identified PfSKP1 as one of PfBXO1’s stable interacting partners, while other major proteins included multiple IMC pellicle and membrane proteins. …”
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Roles of human papillomavirus in cancers: oncogenic mechanisms and clinical use by Yu Zhang, Ke Qiu, Jianjun Ren, Yu Zhao, Ping Cheng

“…The genome of human papillomaviruses is circular, double-stranded DNA that encodes early and late proteins. Each of the proteins is of crucial significance in infecting the epithelium of host cells persistently and supporting viral genome integrating into host cells. …”
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The role of TASK-1 and TRPV1 channels in the male reproductive system by Dawon Kang, Eun-A Ko

“…Furthermore, Leydig cells uniquely express several key proteins, including c-kit, and platelet-derived growth factor receptor α. …”
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A bioinformatic approach to characterize the vitellogenin receptor and the low density lipoprotein receptor superfamily in the newt Cynops orientalis by Chiara Spinsante, Federica Carducci, Elisa Carotti, Adriana Canapa, Davide Bizzaro, Maria Assunta Biscotti, Marco Barucca

“…In tetrapods, information concerning genes encoding these proteins is limited to a few taxa. Here, we report the characterization of VTGR in the amphibian Cynops orientalis. …”
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Sculpting multi-epitope vaccine against Monkeypox viral strains using immunoinformatics by Zaira Rehman, Ammad Fahim, Maryam Irtash

“…The monkeypox virus encodes 190 different proteins. These proteins were shortlisted on the basis of antigenicity, surface expression, allergenicity, and toxicity. …”
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A Review on The Impact of Thermal Stress on Fish Biochemistry by Manoj Kumar Pati, Mohammad Aftabuddin, Prasun Roychowdhury

“…Enzymes involved in metabolic pathways have optimal temperature and pH ranges altered by thermal stress. Heat shock proteins and warm acclimation proteins act as protective mechanisms by preserving the structural integrity of proteins, which is crucial for maintaining proper functionality and cellular responses. …”
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Ethanolamine-induced assembly of microcompartments is required for Fusobacterium nucleatum virulence by Dana S. Franklin, Yi-Wei Chen, Yimin Chen, Manuel Wittchen, Angela Agnew, Alexis Luu, Julian P. Whitelegge, Z. Hong Zhou, Andreas Tauch, Asis Das, Hung Ton-That

“…The formation of F. nucleatum BMCs, containing BMC shell proteins EutLM1M2N, is controlled by a two-component system, EutV-EutW, responsive to EA. …”
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