Proteomic Technology “Lens” for Epithelial-Mesenchymal Transition Process Identification in Oncology by Monica Neagu, Carolina Constantin, Marinela Bostan, Constantin Caruntu, Simona Rebeca Ignat, Sorina Dinescu, Marieta Costache

“…We present herein, using various proteomic technologies, the identification in cancer cell lines and in tumour tissue EMT-related proteins, proteins that are involved in the activation of different cellular pathways. …”
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Cloning, recombinant expression, and characterization of a Rhipicephalus microplus carboxylesterase. [version 1; peer review: 2 approved, 1 not approved] by Michel Labuschagne

“…Conclusions This report provides the necessary information for the tick research community to produce recombinant tick derived CBE proteins and to characterize the recombinant proteins towards substrates of interest.…”
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Expression of the JAK/STAT Signaling Pathway in Bullous Pemphigoid and Dermatitis Herpetiformis by K. Juczynska, A. Wozniacka, E. Waszczykowska, M. Danilewicz, M. Wagrowska-Danilewicz, J. Wieczfinska, R. Pawliczak, A. Zebrowska

“…The localization and expression of selected STAT and JAK proteins were examined by immunohistochemistry and immunoblotting. …”
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Proteomic analysis of Trichoderma harzianum secretome and their role in the biosynthesis of zinc/iron oxide nanoparticles by Micaela B. Gallo, Araceli N. Bader, Andrés Torres-Nicolini, Vera A. Alvarez, Verónica F. Consolo

“…Different profiles of proteins secreted by the fungus grown in the culture media or in the aqueous filtrate were observed through SDS‒PAGE and LC‒MS/MS analysis identifying 99 and 304 proteins, respectively. …”
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Understanding the Molecular Mechanisms of Incomptine A in Treating Non-Hodgkin Lymphoma Associated with U-937 Cells: Bioinformatics Approaches, Part I by Fernando Calzada, Normand García-Hernández, Elihú Bautista, José Manuel Sánchez-López, Miguel Valdes, Claudia Velázquez, Elizabeth Barbosa

“…The molecular docking analysis, which used 23 altered proteins as targets, revealed that <b>IA</b> interacted with all the proteins used. …”
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Applying the Concept of Peptide Uniqueness to Anti-Polio Vaccination by Darja Kanduc, Candida Fasano, Giovanni Capone, Antonella Pesce Delfino, Michele Calabrò, Lorenzo Polimeno

“…Peptide sequences unique to poliovirus proteins and conserved among polio strains might help formulate a specific and universal anti-polio vaccine able to react with multiple viral strains and exempt from the burden of possible cross-reactions with human proteins. …”
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Nano–bio surface interactions, cellular internalisation in cancer cells and e‐data portals of nanomaterials: A review by Ram Dhan Yadav, Abha Chaudhary

“…The biological interaction of proteins present in the body fluid with NMs can change the activity and natural surface properties of NMs. …”
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Sugar transporters of the SWEET family and their role in arbuscular mycorrhiza by A. A. Kryukov, A. O. Gorbunova, T. R. Kudriashova, O. I. Yakhin, A. A. Lubyanov, U. M. Malikov, M. F. Shishova, A. P. Kozhemyakov, A. P. Yurkov

“…A high variability of both the SWEET proteins themselves and their functions is noted along with the fact that the same proteins may perform different functions in different plants. …”
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Cathepsin C Is Involved in Macrophage M1 Polarization via p38/MAPK Pathway in Sudden Cardiac Death by Jialin Dai, Jiangjin Liu, Qiong Zhang, Yang An, Bing Xia, Changwu Wan, Yuanyuan Zhang, Yanni Yu, Jie Wang

“…It was found that CTSC were the most expressed proteins with a significant upward trend in SCD cases. …”
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A Pilot Study of Exosome Proteomic Profiling Reveals Dysregulated Metabolic Pathways in Endometrial Cancer by Feras Kharrat, Valeria Capaci, Andrea Conti, Valentina Golino, Pietro Campiglia, Nour Balasan, Michelangelo Aloisio, Danilo Licastro, Lorenzo Monasta, Federica Caponneto, Antonio Paolo Beltrami, Federico Romano, Giovanni di Lorenzo, Giuseppe Ricci, Blendi Ura

“…This is the largest number of proteins identified in EC serum EVs. After quantification and statistical analysis, we identified 373 significantly (<i>p</i> < 0.05) dysregulated proteins involved in neutrophil and platelet degranulation pathways. …”
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scFv Antibody: Principles and Clinical Application by Zuhaida Asra Ahmad, Swee Keong Yeap, Abdul Manaf Ali, Wan Yong Ho, Noorjahan Banu Mohamed Alitheen, Muhajir Hamid

“…Basically, scFv antibodies produced from phage display can be genetically fused to the marker proteins, such as fluorescent proteins or alkaline phosphatase. …”
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Imaging lipid rafts reveals the principle of ApoE4-induced Aβ upregulation in human neurons by Se-In Lee, Heejin Lim, Na Yeon Kim, Jichang Yu, Joonho Cho, Hyein Lee, Dae Won Moon, Jinsoo Seo

“…Summary: Lipid rafts in plasma membranes are thought to provide a platform for regulating signaling pathways by increasing the expression or proximity of proteins in the same pathway. Despite this understanding, the absence of direct, simultaneous observations of lipid rafts and their affiliated proteins has hindered a comprehensive assessment of their roles across various biological contexts. …”
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The role of aTp-dependent chromatin remodeling factors in chromatin assembly in vivo by Iu. A. Il’ina, A. Yu. Konev

“…Thus, the molecular motor proteins, such as CHD1, function not only in the remodeling of existing nucleosomes but also in de novo nucleosome assembly from DNA and histones in vivo. …”
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Automation-aided construction and characterization of Bacillus subtilis PrsA strains for the secretion of amylases by Felix Hamburger, Niels Schlichting, Michael Eichenlaub, Paul Igor Costea, Christopher Sauer, Stefan Jenewein, Johannes Kabisch, Johannes Kabisch

“…Proteins face an obstacle race on their way to successful folding. …”
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Potential biomarkers for predicting the risk of thyroid cancer in immunosenescence: a population-based and externally validated multi omics study by Qian Li, Yuanyuan Zhao, Jiawei Yan, Chao He

“…ObjectivesGenome-wide association studies (GWAS) have pinpointed several risk loci linked to thyroid cancer; however, the discovery of new plasma proteins implicated in immunosenescence continues to pose significant challenges. …”
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Distinctive blood and salivary proteomics signatures in Qatari individuals at high risk for cardiovascular disease by Ghada Yousif, Selvasankar Murugesan, Mohamed Nadhir Djekidel, Annalisa Terranegra, Giusy Gentilcore, Jean Charles Grivel, Souhaila Al Khodor

“…Our analysis revealed significant differences in the plasma and salivary proteins between the two groups. Pathway enrichment analysis of the differentially detected proteins revealed that the immune system activation and extracellular matrix remodeling are the most enriched pathways in the CVD-HR group. …”
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Menopause mysteries: the exosome-inflammation connection by Aarushi Sultania, Subhashini Brahadeeswaran, Aparna Eledath Kolasseri, Sivaraman Jayanthi, Ramasamy Tamizhselvi

“…It also explores the complex functions of FF exosomal proteins in the pathologies associated with menopause. …”
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N-Acetylglucosamine Functions in Cell Signaling by James B. Konopka

“…Studies with animal cells have revealed that GlcNAc influences cell signaling through the posttranslational modification of proteins by glycosylation. O-linked attachment of GlcNAc to Ser and Thr residues regulates a variety of intracellular proteins, including transcription factors such as NFκB, c-myc, and p53. …”
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Contributions of Matrix Metalloproteinases to Neural Plasticity, Habituation, Associative Learning and Drug Addiction by John W. Wright, Joseph W. Harding

“…It is presumed that while these ECM proteins are weakened, and/or detached, synaptic connections can form resulting in new neural pathways. …”
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Galectin-3: A Novel Marker for the Prediction of Stroke Incidence and Clinical Prognosis by Ahmed Sayed, Malak Munir, Mohamed S. Attia, Badrah S. Alghamdi, Ghulam Md Ashraf, Eshak I. Bahbah, Mohamed Elfil

“…Galectins are a group of proteins expressed by many types of cells and tissues including vasculature, certain immune cells, fibroblasts, and gastrointestinal epithelial cells. …”
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