Mitochondrial Mayhem: How cigarette smoke induces placental dysfunction through MMS19 degradation by Pei Zhou, Feng Jin, Shenshen Yao, Ben Sun, Ni Sun, Hongbo Guan, Xiaomei Liu

“…This study aims to investigate the impact of CS on trophoblast cell proliferation and regulated cell death (RCD) by examining its interference with iron-sulfur cluster (ISC) proteins and the CIA pathway. Exposure to CS disrupted the cytosolic ISC assembly (CIA) pathway, downregulated ISC proteins, and decreased ISC maturation in the placenta of rats exposed to passive smoking. …”
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Oral Tolerance: A New Tool for the Treatment of Gastrointestinal Inflammatory Disorders and Liver-Directed Gene Therapy by Yaron Ilan

“…The use of oral tolerance toward adenoviruses and colitis-extracted proteins for long term gene therapy and alleviation of experimental colitis, and the mechanisms of tolerance induction are presented. …”
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Accumulating the key proteomic signatures associated with delirium: Evidence from systematic review. by Md Parvez Mosharaf, Khorshed Alam, Jeff Gow, Rashidul Alam Mahumud

“…We have accumulated a total of 313 proteins or gene encoded proteins of which 189 were unique. …”
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Fine Tuning of Redox Networks on Multiheme Cytochromes from Geobacter sulfurreducens Drives Physiological Electron/Proton Energy Transduction by Leonor Morgado, Joana M. Dantas, Marta Bruix, Yuri Y. Londer, Carlos A. Salgueiro

“…The detailed thermodynamic characterization of such proteins showed that PpcA and PpcD have an important redox-Bohr effect that might implicate these proteins in the e−/H+ coupling mechanisms to sustain cellular growth. …”
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Effects of laparoscopic sleeve gastrectomy on nonalcoholic fatty liver disease and TGF-β signaling pathway by Hideki Kumagai, Akira Sasaki, Akira Umemura, Keisuke Kakisaka, Takeshi Iwaya, Satoshi S Nishizuka

“…Among these proteins, we focused on five TGF-β-related proteins: asporin, EMILIN-1, platelet factor-4, serglycin, and thrombospondin-1. …”
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A proteomic analysis identifies higher AHSG (Alpha-2-HS-glycoprotein) in saliva of oropharyngeal cancer patients – A potential salivary biomarker by Anu Jain, Aafaque Ahmad Khan, Rajandeep Kaur, Roshan K Verma, Jaimanti Bakshi, Aditi Chatterjee, Amanjit Bal, Sushmita Ghoshal, Arnab Pal

“…Differential expression of proteins in different OPC study cohorts was observed. 15 candidate proteins were selected for validation after analysing the data. …”
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Quantitative Analysis of the Proteome and the Succinylome in the Thyroid Tissue of High-Fat Diet-Induced Hypothyroxinemia in Rats by Baoxiang Hu, Meng Zhao, Dandan Luo, Chunxiao Yu, Shanshan Shao, Lifang Zhao, Yashuang Yang, Xiaohan Zhang, Jiajun Zhao, Ling Gao

“…Overall, 129 differentially expressed proteins were quantified. Downregulated proteins were enriched in the thyroid hormone synthesis and thyroid hormone signaling pathways and were mainly localized in the mitochondria. …”
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Antibodies to Lactobacilli and Bifidobacteria in Young Children with Different Propensity to Develop Islet Autoimmunity by Ija Talja, Anna-Liisa Kubo, Riitta Veijola, Mikael Knip, Olli Simell, Jorma Ilonen, Mari Vähä-Mäkilä, Epp Sepp, Marika Mikelsaar, Meeme Utt, Raivo Uibo

“…We demonstrated that children between the ages of 6 and 12 months had a substantial increase in the frequency of IgG antibodies specific for L. rhamnosus GG proteins. We measured IgG, IgM, and IgA class antibody reactivity against B. adolescentis DSM 20083, B. adolescentis DSM 20086, and B. longum DSM 20088 proteins demonstrating significantly higher IgA responses against B. adolescentis DSM 20083 strain proteins in children who developed islet autoimmunity and T1D later in life. …”
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Proteomic profiling of iPSC and tissue-derived MSC secretomes reveal a global signature of inflammatory licensing by Margeaux Hodgson-Garms, Matthew J. Moore, Mikaël M. Martino, Kilian Kelly, Jessica E. Frith

“…Overall, resting secretomes were defined by extracellular matrix (ECM) and pro-regenerative proteins, while licensed secretomes were enriched in chemotactic and immunomodulatory proteins. iMSC and UC.MSC secretomes contained proteins indicating proliferative potential and telomere maintenance, whereas adult tissue-derived secretomes contained fibrotic and ECM-related proteins. …”
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Proteomic evaluation of pathways associated with phosphine-induced mitochondrial dysfunction and resistance mechanisms in Tribolium castaneum against phosphine fumigation: Whole an... by Donghyeon Kim, Sung-Eun Lee

“…Differentially expressed proteins (DEPs) with cut-off values (4-fold expression difference and p < 0.05) were selected, and 107 proteins were identified in the AUS-07 strain. …”
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Gene expression patterns in larval Schistosoma mansoni associated with infection of the mammalian host. by Sophia J Parker-Manuel, Alasdair C Ivens, Gary P Dillon, R Alan Wilson

“…Genes encoding membrane proteins were prominently up-regulated in the cercaria and/or day 3 schistosomulum.…”
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A Point Mutation in the Iron-Responsive Element of the L-Ferritin in a Family with Hereditary Hyperferritinemia Cataract Syndrome by Karen Wong, Yousef Barbin, Subrata Chakrabarti, Paul Adams

“…The IRE controls ferritin synthesis in response to cytoplasmic iron pools by interacting with regulatory proteins called iron responsive proteins. Mutations in the IRE decrease its affinity for iron responsive proteins, leading to the constitutive synthesis of L-ferritin which results in hyperferritinemia and the intracellular accumulation of ferritin in the lens and eventual cataract formation.…”
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Quantitative glycoproteomics of human milk and association with atopic disease. by Matilda Holm, Mayank Saraswat, Sakari Joenväärä, Antti Seppo, R John Looney, Tiialotta Tohmola, Jutta Renkonen, Risto Renkonen, Kirsi M Järvinen

“…We identified 79 N-glycopeptides from 15 different proteins and found that proteins including immunoglobulin A1, polymeric immunoglobulin receptor, and lactotransferrin displayed significant glycan heterogeneity. …”
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Application and prospects of proteomic technology in inflammation: a review by Senye Wang, Yanhai Chu, Jiajia Yuan, Yiqi Li, Zhenhua Liu, Xiaoyu Chen, Wenyi Kang

“…The differential proteins identified through proteomics can serve as disease biomarkers and target proteins affecting health and can be used for disease diagnosis and health regulation. …”
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A universal method for the purification of C2H2 zinc finger arrays. by Jingchang Liang, Maia Azubel, Guanqiao Wang, Yan Nie, Roger D Kornberg, Andrew J Beel, Pierre-Jean Mattei

“…Here we describe a simple method, involving two chromatographic steps, for the production of homogeneous, functional ZF proteins in high yield (one milligram per liter of bacterial culture), and we demonstrate the generality of this method by applying it to a diverse set of eight C2H2-type ZF proteins. …”
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WWTR1-AS1 LncRNA as a Novel Potential Diagnostic and Prognostic Biomarker in Breast Cancer by Mohadese Safabakhsh, Sohrab Boozarpour, Kamran Ghaedi, Mina Lashkarboloki, Shaaban Ghalandarayeshi

“…This study aimed to introduce a central regulatory lncRNA based on differentially expressed proteins in breast cancer and evaluate its expression level in breast tissues. …”
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Biomolecules of the Horseshoe Crab’s Hemolymph: Components of an Ancient Defensive Mechanism and Its Impact on the Pharmaceutical and Biomedical Industry by Md. Ashrafuzzaman, Mamudul Hasan Razu, Nazmir-Nur Showva, Tohmina Afroze Bondhon, Md. Moniruzzaman, Sad Al Rezwan Rahman, Md. Raisul Islam Rabby, Fatema Akter, Mala Khan

“…L-granules contain most clotting proteins, which are necessary for hemolymph coagulation. …”
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Viral entry mechanisms: the role of molecular simulation in unlocking a key step in viral infections by Mariana Valério, Carolina C. Buga, Manuel N. Melo, Cláudio M. Soares, Diana Lousa

“…Simulation studies have provided deep insight into the function of the proteins responsible for attaching to the host receptors and promoting membrane fusion (fusion proteins), deciphering interactions between these proteins and receptors, and shedding light on the functional significance of key regions, such as the fusion peptide. …”
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Formation of hybrid carriers based on albumin and polyoxometalate for targeted drug delivery by M.O. Tonkushina, I.D. Gagarin, V.R. Gavrilyuk, K.A. Piunov, A.A. Ostroushko

“… The use of proteins to create the targeted drug delivery systems is a promising approach in medicine and has many advantages. …”
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Blueprint for a high-performance biomaterial: full-length spider dragline silk genes. by Nadia A Ayoub, Jessica E Garb, Robin M Tinghitella, Matthew A Collin, Cheryl Y Hayashi

“…These genes encode the MaSp1 and MaSp2 proteins that compose the black widow's high-performance dragline silk. …”
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