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12061
Genome-wide characterization and expression analysis of the ADF gene family in response to salt and drought stress in alfalfa (Medicago sativa)
Published 2025-01-01“…Actin-depolymerizing factors (ADFs) represent a significant class of actin-binding proteins that regulate the dynamic alterations in the microfilament framework, thereby playing a pivotal role in plant growth and development. …”
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12062
Is The SARS-CoV2 Evolved in Human Being: A prospective Genetic Analysis
Published 2020-12-01“…The phylogenetic trees for all human coronaviruses with the novel Coronavirus have been built using a several complete amino acid sequences of the four known structural proteins, S (spike), E (envelope), M (membrane), and N (nucleocapsid). …”
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12063
CAVIN-2 positively correlates with diabetic PAD and promotes LDL transcytosis by inhibiting eNOS activation
Published 2025-12-01“…However, the potential contributions of additional caveolae proteins to atherosclerosis necessitate further exploration. …”
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12064
Insulin-Attenuated Inflammatory Response of Dendritic Cells in Diabetes by Regulating RAGE-PKCβ1-IRS1-NF-κB Signal Pathway: A Study on the Anti-Inflammatory Mechanism of Insulin in...
Published 2020-01-01“…The concentrations of IFN-γ and TNF-α were calculated using ELISA kits, and the proteins were detected using western blot. Results. …”
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12065
Strength Training Session Induces Important Changes on Physiological, Immunological, and Inflammatory Biomarkers
Published 2018-01-01“…The strength training session elevated the levels of apelin and fatty acid-binding proteins-3 (FABP3) in both groups and brain-derived neurotrophic factor (BDNF) in TG. …”
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12066
Chromosome synapsis, recombination and epigenetic modification in rams heterozygous for metacentric chromosome 3 of the domestic sheep Ovis aries and acrocentric homologs of the ar...
Published 2019-05-01“…We examined synapsis, recombination, and epigenetic modification of chromosomes involved in this rearrangement in heterozygous rams using immunolocalization of key proteins of meiosis. In the majority of cells, we observed complete synapsis between the sheep metacentric chromosome and two argali acrocentric chromosomes with the formation of a trivalent. …”
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12067
Gut microbiota modulation via fecal microbiota transplantation mitigates hyperoxaluria and calcium oxalate crystal depositions induced by high oxalate diet
Published 2025-12-01“…Furthermore, FMT treatment could significantly decrease the urinary oxalate excretion and CaOx crystal depositions in rat kidneys via, at least in part, upregulating the expressions of intestinal barrier proteins and oxalate transporters in the intestine. …”
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12068
Exploring the anti-inflammatory effects of phytochemicals in attenuating interstitial cystitis-a literature review
Published 2025-02-01“…Uroprotective outcomes of these phytochemicals have been found to result in diminished oxidative stress and restoration of glutathione, superoxide dismutase, and related proteins in the inflamed bladder tissue. Many in vivo studies involving cyclophosphamide-induced interstitial cystitis have confirmed these findings. …”
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12069
USP39 phase separates into the nucleolus and drives lung adenocarcinoma progression by promoting GLI1 expression
Published 2025-01-01“…Methods GFP-USP39 fusion proteins were analyzed for LLPS properties using immunofluorescence, fluorescence recovery after photobleaching (FRAP) and in vitro LLPS assays. …”
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12070
Genomic characterization of Achromobacter genogroup 20 and identification of a potential species-specific marker
Published 2025-01-01“…The genome included coding sequences for three putative β-lactamases (one new OXA type-class D β -lactamase and two new class C), 32 efflux pump proteins, two aminoglycoside-modifying enzymes and a dihydropteroate synthase; also, substitutions in parC and parE were detected. …”
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12071
Almond snacking modestly improves diet quality and waist circumference but not psychosocial assessments and other cardiometabolic markers in overweight, middle-aged adults: A rando...
Published 2025-03-01“…Almonds are a plant-based source of lipids, proteins, fibers, micronutrients, and phytochemicals associated with cardiometabolic health benefits. …”
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12072
ANGPTL4: A Predictive Marker for Diabetic Nephropathy
Published 2019-01-01“…In this study, we examined levels of circulating ANGPTL4 in people with diabetic nephropathy (DN) and its association with established DN-associated proteins such as IGFBP1 and IGFBP4. Methods. We quantified circulating ANGPTL4, IGFBP1, IGFBP3, and IGFBP4 in fasting plasma samples of 122 Kuwaiti participants using a multiplexing assay. …”
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12073
Characterization of a chitinase from Trichinella spiralis and its immunomodulatory effects on allergic airway inflammation in mice
Published 2025-01-01“…The findings provide new insights into helminth-derived proteins as promising candidates for immune-based therapies. …”
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12074
The role of CTGF and MFG-E8 in the prognosis assessment of SCAP: a study combining machine learning and nomogram analysis
Published 2025-01-01“…By conducting a prospective analysis, this study has explored the relationship between these two proteins and the diagnosis and mortality of SCAP patients. …”
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12075
Impact of MMP2 rs243865 and MMP3 rs3025058 Polymorphisms on Clinical Findings in Alzheimer’s Disease Patients
Published 2021-01-01“…Matrix metalloproteinases (MMPs) are endopeptidases involved in the cleavage of extracellular matrix proteins and basement membrane compounds. In the brain, the pathological role of MMPs includes the disruption of the blood-brain barrier leading to the induction of neuroinflammation. …”
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12076
Cross-Stressful Adaptation to Drought and High Salinity Is Related to Variable Antioxidant Defense, Proline Metabolism, and <i>Dehydrin b</i> Expression in White Clover
Published 2025-01-01“…The objective of this study was to explore DP-regulated cross tolerance to salt stress and SP-induced cross tolerance to drought associated with changes in growth, antioxidant defense, proline metabolism, and the expression of the dehydration-responsive gene <i>Dehydrin b</i> involved in the stabilization of membrane systems, cryoprotection of intracellular proteins, and enhancement in water retention capacity in white clover (<i>Trifolium repens</i>). …”
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12077
MicroRNA-140-5p inhibits cellular proliferation, migration and invasion by downregulating AKT/STAT3/NF-κB pathway in breast carcinoma cells
Published 2022-12-01“…Expression levels of target proteins were determined using Western blotting. In addition, experiments on animal models were performed to study the possible role of miR-140-5p in tumorigenesis of breast carcinoma cells. …”
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12078
Exosomes Derived from CXCR4-Overexpressing BMSC Promoted Activation of Microvascular Endothelial Cells in Cerebral Ischemia/Reperfusion Injury
Published 2020-01-01“…In addition, cobalt chloride (COCl2) can increase the expression of β-catenin and Wnt-3, while ExoCon can reduce the expression of these proteins (P<0.05). ExoCXCR4 can further attenuate the activation of Wnt-3a/β-catenin pathway (P<0.05). …”
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12079
Synergistic anti-oxidative/anti-inflammatory treatment for acute lung injury with selenium based chlorogenic acid nanoparticles through modulating Mapk8ip1/MAPK and Itga2b/PI3k-AKT...
Published 2025-01-01“…Further mechanistic research revealed that CHSe NPs directly acted on and modulated the expression of Mapk8ip1 and Itga2b, which were upstream proteins of MAPK signaling pathway and PI3K-Akt signaling pathway, therefore impeding the cyclic synergy between oxidative stress and inflammatory dysregulation. …”
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12080
Investigating the antioxidant and anti-inflammatory potential of Nypa fruticans: a multifaceted approach to skin protection and aging
Published 2025-01-01“…Furthermore, NF restored the expression of key skin barrier-related proteins such as serine peptidase inhibitor kazal type 5 (SPINK5), collagen type I alpha 1 chain (COLIA1), loricrin (LOR), aquaporin-3 (AQP3), and filaggrin (FLG). …”
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