The simplified GLIM criteria for assessment of malnutrition and its correlation with clinical outcomes in Crohn’s disease patients by Xiaomei Song, Xiaomei Song, Xiaomei Song, Xiaoxin Zhou, Xiaoxin Zhou, Hao Wang, Hong Guo, Jian Yang, Jian Yang

“…Additionally, the duration of disease (p = 0.021), C-reactive protein (p = 0.014) and prealbumin (p = 0.014) were independent factors influencing endoscopic remission in patients with CD.ConclusionMalnutrition identified using the simplified GLIM criteria is associated with age, CDAI, behavior, hemoglobin, and albumin, providing prognostic value for endoscopic remission in CD patients.…”
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Effects of Iron and Vitamin C on Growth Performance, Iron Utilization, Antioxidant Capacity, Nonspecific Immunity, and Disease Resistance to Aeromonas hydrophila in Chinese Mitten... by Ying Song, Xinyu Cai, Xianyong Bu, Shubin Liu, Mingqi Song, Yiwen Yang, Xiaodan Wang, Qingchao Shi, Jianguang Qin, Liqiao Chen

“…Dietary 700.90 mg/kg of vitamin C significantly improved the expression levels of divalent metal ion transporter 1, ferroportin, and iron regulation protein in the intestine and hepatopancreas when supplemented with 92.25 and 143.00 mg/kg of iron (P<0.05) and enhanced the transferrin content in hemolymph and iron deposition in the hepatopancreas when supplemented with 92.25 and 143.00 mg/kg of iron (P<0.05). …”
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Evaluating H2BC9 as a potential diagnostic and prognostic biomarker in head and neck squamous cell carcinoma by Lanhua Wu, Liang Li, Mingjing Zhu, Ziyan Zhou, Xuejin Su, Yueming Jiang, Min Kang, Li Jiang

“…H2BC9 expression was validated using the Human Protein Atlas database, qRT-PCR, and western blotting. …”
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Food groups, macronutrient intake and objective measures of total carotenoids and fatty acids in 16-to-24-year-olds following different plant-based diets compared to an omnivorous... by Synne Groufh-Jacobsen, Christel Larsson, Isabelle Mulkerrins, Dagfinn Aune, Anine Christine Medin

“…The energy percentage (E%) of protein, carbohydrates and total fat were within the Nordic Nutrition Recommendations 2023 across groups. …”
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Performance of Banana Peelings Extract as A Natural Coagulant in the Treatment of Surface Water Case Study: River Rwizi, Mbarara. by Asingya, Derrick

“…The use of banana peelings extract helped in the removal of turbidity from the water by providing a protein content pectin and other mineral components like potassium which helped in neutralizing the negatively charged suspended solids in water by reducing the zeta potential of the river water thus making the particles to come together forming flocs to settle at the bottom. …”
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Novel carbon dots with dual Modulatory effects on the bone marrow and spleen as a potential therapeutic candidate for treating spinal cord injury by Junjin Li, Hongda Wang, Yuanquan Li, Chunzhen Wang, Haiwen Feng, Yilin Pang, Jie Ren, Chuanhao Li, Erke Gao, Dejing Zhang, Dunxu Hu, Pengtian Zhao, Han Ding, Baoyou Fan, Tao Zhang, Xiaomeng Song, Zhijian Wei, Guangzhi Ning, Yong-Qiang Li, Shiqing Feng

“…These effects are mediated through the downregulation of CCAAT enhancer binding protein-β expression in the spleen and the upregulation of FZD4 protein expression in Lin− Sca-1+ c-kit+ cells (LSKs) within the bone marrow. …”
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ANO7 expression in the prostate modulates mitochondrial function and lipid metabolism by Christoffer Löf, Nasrin Sultana, Neha Goel, Samuel Heron, Gudrun Wahlström, Andrew House, Minna Holopainen, Reijo Käkelä, Johanna Schleutker

“…Methods We performed RNA-sequencing (RNA-seq) on RWPE1 cells engineered to express ANO7 protein, alongside the analysis of a single-cell RNA-sequencing (scRNA-seq) dataset and RNA-seq from prostate tissues. …”
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Efficacy of Multiple Micronutrients Fortified Milk Consumption on Iron Nutritional Status in Moroccan Schoolchildren by Imane El Menchawy, Asmaa El Hamdouchi, Khalid El Kari, Naima Saeid, Fatima Ezzahra Zahrou, Nada Benajiba, Imane El Harchaoui, Mohamed El Mzibri, Noureddine El Haloui, Hassan Aguenaou

“…Hemoglobin (Hb) was measured in situ by Hemocue device; ferritin and C Reactive Protein were assessed in serum using ELISA and nephelometry techniques, respectively. …”
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Interactive effect of dietary metabolizable energy levels with amino acid density in male broiler chickens: Carcass yield, nutrient intake, digestibility and excretion by Mehdi Toghyani, Shemil MacElline, Peter H. Selle, Sonia Y. Liu

“…Dietary treatments didn't affect ileal digestibility of crude protein and gross energy, except for improved starch digestibility with 6.0% AA density (P < 0.01). …”
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Impact of Extended Membrane Rupture on Neonatal Inflammatory Responses and Composite Neonatal Outcomes in Early-Preterm Neonates—A Prospective Study by Maura-Adelina Hincu, Liliana Gheorghe, Luminita Paduraru, Daniela-Cristina Dimitriu, Anamaria Harabor, Ingrid-Andrada Vasilache, Iustina Solomon-Condriuc, Alexandru Carauleanu, Ioana Sadiye Scripcariu, Dragos Nemescu

“…<b>Results</b>: PROMs and high c-reactive protein (CRP) values significantly increased the risk of composite outcome 1 occurrence by 14% (95%CI: 1.03–1.57, <i>p</i> < 0.001). …”
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Clinical outcomes of COVID-19 in patients with liver cirrhosis - a propensity-matched analysis from a multicentric Brazilian cohort by Luanna Silva Monteiro Menezes, Pedro Ferrari Sales da Cunha, Magda Carvalho Pires, Lucas Rocha Valle, Flávia Carvalho Cardoso Costa, Maria Angélica Pires Ferreira, Milton Henriques Guimarães Júnior, Saionara Cristina Francisco, Marcelo Carneiro, Daniel Vitório Silveira, Fernando Graça Aranha, Rafael Lima Rodrigues de Carvalho, Teresa Cristina de Abreu Ferrari, Milena Soriano Marcolino

“…Patients with cirrhosis had lower median hemoglobin levels (10.8 vs. 13.1 g/dl), lower platelets (127,000 vs. 200,000 cells/mm3), and leukocyte counts, as well as lower median C-reactive protein (63.0 vs. 76.0 p = 0.044) when compared to controls. …”
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Inhaled [D-Ala2]-Dynorphin 1-6 Prevents Hyperacetylation and Release of High Mobility Group Box 1 in a Mouse Model of Acute Lung Injury by Vladislav N. Karkischenko, Veronika I. Skvortsova, Melik T. Gasanov, Yuriy V. Fokin, Maxim S. Nesterov, Nataliya V. Petrova, Oxana V. Alimkina, Igor A. Pomytkin

“…HMGB1 is a ubiquitous nuclear DNA-binding protein whose biological function depends on posttranslational modifications, its redox state, and its cellular localization. …”
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Interleukin-1 Gene Variability and Plasma Levels in Czech Patients with Chronic Periodontitis and Diabetes Mellitus by Petra Borilova Linhartova, Hana Poskerova, Marie Tomandlova, Jirina Bartova, Katerina Kankova, Antonin Fassmann, Lydie Izakovicova Holla

“…Haplotype analysis suggests that variability in IL-1 gene cluster may be one of the factors in the CP and T1DM pathogenesis, although single variants of these polymorphisms are not substantial for protein production.…”
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Combination effects of Pistachio hull and carfilzomib on NF-κB p65, MDR1, MRP1, and Caspase3 gene expression in breast cancer cell line by Zahra Mirzaei, Sadegh Zarei, Ahmadreza Sayadi, Reza Hosseiniara, Mojgan Noroozi Karimabad, Mehdi Mahmoodi

“…Real-time PCR results demonstrated significant alterations in the expression of MDR1, MRP1, NF-κB p65, and Caspase3 genes, along with changes in NF-κB p65 protein levels in both cell lines following treatment with Pistachio hull extract, CFZ, or their combination compared to the control group (p < 0.05). …”
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Uncovering a novel SERPING1 pathogenic variant: insights into the aggregation of C1-INH in hereditary angioedema by Lingxi Jiang, Chao Dai, Suyang Duan, Tingting Wang, Chunbao Xie, Luhan Zhang, Zimeng Ye, Xiumei Ma, Yi Shi

“…Our observations indicate that this variant leads to an increase in the accumulation of C1-INH within the endoplasmic reticulum (ER), resulting in the upregulation of GRP75 protein expression. This cascade of events resulted in Ca2+ overload, disruption of mitochondrial structure and function, and eventually triggered apoptosis. …”
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Investigation of the Mechanism Underlying Calcium Dobesilate-Mediated Improvement of Endothelial Dysfunction and Inflammation Caused by High Glucose by Yijun Zhou, Chaojun Qi, Shu Li, Xinghua Shao, Zhaohui Ni

“…After PTX3 gene silencing, the urine protein and renal function of db/db mice were ameliorated, the glomerular extracellular matrix was decreased, and the expression of p-eNOS/eNOS was increased. …”
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GC1126A, a novel ADAMTS13 mutein, evades autoantibodies in immune-mediated thrombotic thrombocytopenic purpura by Heechun Kwak, Gahee Choi, Suyong Kim, Ji-Min Park, Youngeun Kwon, Yongmin Lee, Chaemok Lee, Shangbin Yang, Spero Cataland, Sunghyun Kim, Soo-Mee Bang, Jae-Ho Yoon, Wooin Lee, Hyun-Ja Nam

“…Most patients with iTTP have autoantibodies against specific domains of the ADAMTS13 protein, particularly the cysteine-rich and spacer domains. …”
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PARylation of HMGA1 desensitizes esophageal squamous cell carcinoma to olaparib by Xin‐Yuan Lei, Kai‐Yue He, Qiu‐Tong Li, Lei Zhang, Dan‐Hui Wu, Jing‐Yu Yang, Jin‐Rong Guo, Meng‐Jie Liu, Zi‐Long Zhao, Jun‐Qi Li, Huai Liu, Yuan Zhao, Yu‐Jia Li, Qian‐Hui Sun, Chen‐Guang Wu, Yun‐Fan Wang, Geng‐Sheng Cao, Gang Wang, Yong‐Ping Jian, Zhi‐Xiang Xu

“…This modification enhances the accumulation of Ku70/Ku80 at the site of DNA damage and activates the DNA‐dependent protein kinase catalytic subunit, facilitating nonhomologous end‐joining repair. …”
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Rescue of in vitro models of CSF1R-related adult-onset leukodystrophy by iluzanebart: mechanisms and therapeutic implications of TREM2 agonism by Kelley C. Larson, Frederick W. Gergits, Abigail J. Renoux, Elizabeth J. Weisman, Borislav Dejanovic, Liyue Huang, Bhaumik Pandya, Donald G. McLaren, Berkley A. Lynch, Richard Fisher, Evan Thackaberry, David Gray, Francois Gaudreault, Christian Mirescu

“…Proliferation of microglia, changes in protein levels of specific chemokines identified by gene expression analysis, and increased CSF1R levels were also confirmed in vivo. …”
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