Immune response profiling of HERV-W envelope proteins in multiple sclerosis: potential biomarkers for disease progression by Stefano Ruberto, Stefano Ruberto, María I. Domınguez-Mozo, M. Angel Garcıa-Martınez, Davide Cossu, Davide Cossu, Leonardo A. Sechi, Leonardo A. Sechi, Roberto Alvarez-Lafuente

“…IntroductionThe envelope proteins syncytin-1 and pHERV-W from the Human Endogenous Retroviral family ‘W’ (HERV-W) have been identified as potential risk factors in multiple sclerosis (MS). …”
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Choice white grease used for manufacturing a protein-encapsulated fat blend source for neonatal calves by David P. Casper, Mark F. Scott

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High Prevalence of Neutrophil Cytoplasmic Autoantibodies in Infants with Food Protein-Induced Proctitis/Proctocolitis: Autoimmunity Involvement? by Alena Sekerkova, Martin Fuchs, Eva Cecrdlova, Veronika Svachova, Ivana Kralova Lesna, Ilja Striz, Helena Tlaskalova-Hogenova

“…Background. Food protein-induced proctitis/proctocolitis (FPIP) is the most common noninfectious colitis in children in the first year of life. …”
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Lactobacillus crispatus S-layer proteins modulate innate immune response and inflammation in the lower female reproductive tract by Alexiane Decout, Ioannis Krasias, Lauren Roberts, Belen Gimeno Molina, Chloé Charenton, Daniel Brown Romero, Qiong Y. Tee, Julian R. Marchesi, Sherrianne Ng, Lynne Sykes, Phillip R. Bennett, David A. MacIntyre

“…Anti-inflammatory action of L. crispatus is regulated by surface layer protein (SLPs)-mediated shielding of TLR ligands and selective interaction with the anti-inflammatory receptor DC-SIGN. …”
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Influences of age and sex on the diagnostic accuracy of human epididymis secretory protein 4 for malignant pleural effusion by Qian Yang, Yan Niu, Qianghua Zhou, Dan-Ni Yang, Hong-Zhe Zhu, Cheng Yan, Su-Na Cha, Ting-Wang Jiang, Li Yan, Wen-Qi Zheng, Jian-Xun Wen, Zhi-De Hu

Subjects: “…Human epididymal protein 4…”
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Effect of ionic strength and mixing ratio on complex coacervation of soy protein isolate/Flammulina velutipes polysaccharide by Junmiao Zhang, Hengjun Du, Ning Ma, Lei Zhong, Gaoxing Ma, Fei Pei, Hui Chen, Qiuhui Hu

Subjects: “…Soy protein isolate…”
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Encapsulation of docosahexaenoic acid (DHA) using self-assembling food-derived proteins for efficient biological functions by Yumeng Liu, Kaixin Cao, Tong Li, Delun Mu, Naiqi Zhang, Ying Wang, Rina Wu, Junrui Wu

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IL-7 Induces an Epitope Masking of γc Protein in IL-7 Receptor Signaling Complex by Tae Sik Goh, Yuna Jo, Byunghyuk Lee, Geona Kim, Hyunju Hwang, Eunhee Ko, Seung Wan Kang, Sae-Ock Oh, Sun-Yong Baek, Sik Yoon, Jung Sub Lee, Changwan Hong

“…We demonstrate here that 4G3, TUGm2, and 3E12 epitope masking of γc protein are induced in the presence of IL-7, indicating that the epitope alteration is induced by IL-7 binding to the preassembled receptor core. …”
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Temporal expression of bacterial proteins instructs host CD4 T cell expansion and Th17 development. by Seung-Joo Lee, James B McLachlan, Jonathan R Kurtz, Danhua Fan, Sebastian E Winter, Andreas J Baumler, Marc K Jenkins, Stephen J McSorley

“…Here we visualized multiple CD4 T cell responses to temporally expressed proteins in Salmonella-infected mice. Flagellin-specific CD4 T cells expanded and contracted early, differentiated into Th1 and Th17 lineages, and were enriched in mucosal tissues after oral infection. …”
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Oxidative stress induced protein aggregation via GGCT produced pyroglutamic acid in drug resistant glioblastoma by Deanna Tiek, Xiao Song, Xiaozhou Yu, Runxin Wu, Rebeca Iglesia, Alicia Catezone, Katy McCortney, Jordain Walshon, Craig Horbinski, Pouya Jamshidi, Rudolph Castellani, Robert Vassar, Jason Miska, Bo Hu, Shi-Yuan Cheng

“…We further observe that the byproduct of GGCT—pyroglutamic acid—can bind aggregating proteins and that genetic and pharmacological inhibition of GGCT prevents protein aggregation. …”
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RETRACTED: Bamboo cellulose based single cell protein and nanocellulose by dilute sulfuric acid hydrolysis and fermentation by Ngoc Ho Khac, Rakhmatullina A.P., Dien Le Quang, Chung Nguyen Hoang, Dung Ha Thi, Trang Tran Y. Doan

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The dynamin-related protein PfDyn2 is essential for both apicoplast and mitochondrial fission in Plasmodium falciparum by Alexander A. Morano, Wei Xu, Francesca M. Navarro, Neeta Shadija, Jeffrey D. Dvorin, Hangjun Ke

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Protein kinase inhibitors as targeted therapy for glioblastoma: a meta-analysis of randomized controlled clinical trials by José Pinto-Fraga, Celia García-Chico, Simone Lista, Pedro Miguel Lacal, Giuseppe Carpenzano, Maurizio Salvati, Alejandro Santos-Lozano, Grazia Graziani, Claudia Ceci

“…Upon disease progression, the anti-vascular endothelial growth factor-A (VEGF-A) monoclonal antibody bevacizumab, can be considered.Given the limited efficacy of pharmacological treatments, particularly for the recurrent disease, several molecularly targeted interventions have been explored, such as small-molecule protein kinase inhibitors (PKIs), inhibiting tyrosine kinase growth factor receptors and downstream signaling pathways involved in GBM angiogenesis and infiltrative behavior.This meta-analysis, based on searches in PubMed and Web Of Science, evaluated 12 randomized controlled trials (RCTs) examining PKIs in patients with newly diagnosed or recurrent GBM. …”
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Study of the role of transmembrane emp24 domain-containing protein 2 in oral squamous cell carcinoma by RUAN Zhao-wei, JIAO Xue-feng, XIAO Gao-tian, CHEN Jin-ling, LI Jun, LV Shu-ying

“…Abstract Objective This study aimed to investigate the role of transmembrane emp24 domain-containing protein 2 (TMED2) in oral squamous cell carcinoma (OSCC). …”
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Porphyromonas gingivalis associates with the presence of anti-citrullinated protein antibodies, but not with the onset of arthritis: studies in an at-risk population by Helga Westerlind, Linda Mathsson-Alm, Alexandra Circiumaru, Aase Hensvold, Karin Lundberg, Jan Potempa, Yogan Kisten, Charlotte De Vries, Marina Dehara, Barbara Potempa

“…Objective The antibody response against Porphyromonas gingivalis (Pg) is elevated in rheumatoid arthritis (RA), especially in patients with anti-citrullinated protein antibodies (ACPA). Here, we investigated whether antibodies against the Pg virulence factor arginine gingipain (Rgp) are associated with the RA-risk phase and development of arthritis.Methods At-risk individuals were included in a prospective study (Risk-RA) based on a positive anti-cyclic citrullinated peptide 2 (CCP2) antibody test, and having musculoskeletal complaints but no signs of arthritis. …”
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Anti-Inflammatory Functions of Protein C Require RAGE and ICAM-1 in a Stimulus-Dependent Manner by Natascha Braach, Kirsten Buschmann, Johanna Pflaum, Hannes Hudalla, Lutz Koch, Eduard Ryschich, Johannes Poeschl, David Frommhold

“…Using different inflammatory mouse models we investigated how RAGE and ICAM-1 are involved in anti-inflammatory functions of protein C (PC; Ceprotin, 100 U/kg). We found that, depending on the stimulus, RAGE and ICAM-1 are cooperatively involved in PC-induced inhibition of leukocyte recruitment in cremaster models of inflammation. …”
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Neuroprotective Role of Transchalcone in Parkinson‘s Disease through AMP-activated Protein Kinase-mediated Signaling Pathway by Yao Cheng, Shaik Althaf Hussain, Turki Mayudh Alrubie, Xiaomin Zhang

Subjects: “…amp-activated protein kinase…”
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An overview of ELISA: a review and update on best laboratory practices for quantifying peptides and proteins in biological fluids by Suleyman Aydin, Elif Emre, Kader Ugur, Mustafa Ata Aydin, İbrahim Sahin, Vedat Cinar, Taner Akbulut

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Analysis of Mannose‐Binding Lectin Protein and mRNA Levels on Selected Chicken Breeds in South Africa by Peter Ayodeji Idowu, Takalani J. Mpofu, Oliver T. Zishiri, Khathutshelo A. Nephawe, Bohani Mtileni

“…Objective To detect and quantify the MBL protein concentration and chicken MBL expression in selected chicken breeds in South Africa. …”
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Kruppel-family zinc finger proteins as emerging epigenetic biomarkers in head and neck squamous cell carcinoma by Patrick Pearson, Kendra Smith, Nilita Sood, Elizabeth Chia, Alicia Follett, Michael B. Prystowsky, Simon Kirby, Thomas J. Belbin

“…While expression of these proteins in HEK-293 cells produced full-length protein, only truncated copies could be expressed in head and neck cancer cells (UM-SCC-1). …”
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