Dietary Lactiplantibacillus plantarum KX041 attenuates colitis-associated tumorigenesis and modulates gut microbiota by Tao Wang, Panpan Wang, Li Yin, Xiuchao Wang, Yuanyuan Shan, Yanglei Yi, Yuan Zhou, Bianfang Liu, Xin Wang, Xin Lü

“…Moreover, this probiotic could ameliorate the damage of intestinal barrier by recovering tight junction protein expression (like Occludin, Claudin-1, and ZO-1) and preventing goblet cell loss. …”
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Potential Research Tool of Stem Cells from Human Exfoliated Deciduous Teeth: Lentiviral Bmi-1 Immortalization with EGFP Marker by Siqi Yao, Lingping Tan, Huan Chen, Xiaojun Huang, Wei Zhao, Yan Wang

“…In this study, we generated a Bmi-1-immortalized SHED cell line with an enhanced green fluorescent protein (EGFP) marker (SHED-Bmi1-EGFP) using lentiviral transduction. …”
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Bacteriological quality and predictors of raw meat collected from municipal slaughterhouse and butcher shops in northeast, Ethiopia by Leykun Berhanu, Adinew Gizeyatu, Masresha Abebe, Daniel Teshome, Mohammed Aragaw, Gete Berihun

“…BackgroundMeat is a good source of protein in the human diet, and more than three-quarters of the world’s population consumes it. …”
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Bioactive Compounds from Propolis on Bone Homeostasis: A Narrative Review by Vanessa Bertolucci, André Felipe Ninomiya, Giovanna Barbarini Longato, Luisa Oliveira Kaneko, Nilson Nonose, Pedro Paulo Menezes Scariot, Leonardo Henrique Dalcheco Messias

“…In summary, these compounds modulate signaling pathways, including nuclear factor kappa beta, wingless-related integration site, mitogen-activated protein kinase, vascular endothelial growth factor, and reactive oxygen species. …”
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A panel of cancer testis antigens in squamous cell carcinoma of the lung, head and neck, and esophagus: implication for biomarkers and therapeutic targets by Lin Li, Xin Zhang, Jiayao Yan, Jingyi Guo, Fangcen Liu, Xiao Wei, Qin Liu, Kongcheng Wang, Baorui Liu

“…Abstract This study aims to investigate the expression of seven cancer testis antigens (MAGE-A1, MAGE-A4, MAGE-A10, MAGE-A11, PRAME, NY-ESO-1 and KK-LC-1) in pan squamous cell carcinoma and their prognostic value, thus assessing the potential of these CTAs as immunotherapeutic targets. The protein expression of these CTAs was evaluated by immunohistochemistry in 60 lung squamous cell carcinoma (LUSC), 62 esophageal squamous cell carcinoma (ESCA) and 62 head and neck squamous cell carcinoma (HNSC). …”
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Evaluation of Humoral Immunity to Mycobacterium tuberculosis-Specific Antigens for Correlation with Clinical Status and Effective Vaccine Development by Mamiko Niki, Maho Suzukawa, Shunsuke Akashi, Hideaki Nagai, Ken Ohta, Manabu Inoue, Makoto Niki, Yukihiro Kaneko, Kozo Morimoto, Atsuyuki Kurashima, Seigo Kitada, Sohkichi Matsumoto, Koichi Suzuki, Yoshihiko Hoshino

“…Using Enzyme-Linked ImmunoSpot and Enzyme-Linked ImmunoSorbent Assays, we observed less correlation of both CMI and IgG titers with patient clinical status, including serum concentration of C reactive protein. However, IgA titers against Mtb were significantly correlated with clinical status, suggesting that specific IgA antibodies protect against Mtb proliferation. …”
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High-Fiber Extruded Purple Sweet Potato ( Ipomoea batatas ) and Kidney Bean ( Phaseolus vulgaris ) Extends the Feeling of Fullness by Eny Palupi, Naufal Muharam Nurdin, Ghina Mufida, Fadhilah Nur Valentine, Ricter Pangestika, Rimbawan Rimbawan, Ahmad Sulaeman, Dodik Briawan, Fitry Filianty

“…The product with the highest substitution (40%) of kidney bean was selected as the best based on the sensory acceptability and nutritive value – contents of protein and total fiber were 13.20 and 17.00 g in 100 g dry matter, respectively. …”
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Modulating the anti-inflammatory and barrier protective effects on intestinal epithelial cells utilizing an aqueous Aspalathus linearis extract in vitro by Shana De Bruyn-Orr, Stefan Abel, Mariam Rado, Mariska Lilly

“…Intestinal porcine epithelial cells (IPEC-J2) were pre-treated with either unfermented or fermented aqueous rooibos extracts (0.1 and 0.05 mg/ml) then exposed to 10 µg/ml of Escherichia coli lipopolysaccharide (LPS). Cell viability, protein and gene expression of pro-inflammatory cytokines were investigated to determine the anti-inflammatory effect of both extracts. …”
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Effects of nintedanib on circulating biomarkers of idiopathic pulmonary fibrosis by R. Gisli Jenkins, Vincent Cottin, Yasuhiko Nishioka, Imre Noth, Eric S. White, Carina Ittrich, Claudia Diefenbach, Klaus B. Rohr, Moisés Selman, Toby M. Maher

“…Results 346 subjects were treated (116 randomised to nintedanib, 230 to placebo). Surfactant protein D (SP-D) and cancer antigen 125 (CA-125), markers of epithelial injury, decreased in subjects treated with nintedanib versus placebo. …”
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The Nitrogen Fixation Characteristics of Terrestrial Nitrogen-Fixing Cyanobacteria and Their Role in Promoting Rice Growth by Lei Wu, Ji Dong, Jian Song, Yuan Zhu, Songhao Che, Xueting Qin, Yufeng Xu, Shiqi Tian, Dongchao Wang, Ping Tian, Xiaoshuang Wei, Xue Yang, Meiying Yang, Zhihai Wu

“…The total nitrogen content of rice leaves treated with GD2 increased by 48.73%, and the soluble protein content increased by 52.89%. GD2 has great potential as an excellent nitrogen-fixing cyanobacteria inoculant for rice, suitable for agricultural production. …”
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Segmental analysis of human hair reveals intra-annual variation in 25(OH)D3 concentrations in modern and archaeological individuals by Kate Britton, Orsolya Czére, Eléa Gutierrez, Linda M. Reynard, Eamon Laird, Gary Duncan, Baukje de Roos

“…Results suggest possible positive correspondence of 25(OH)D3 levels with season in this archaeological individual, and possibly with marine protein consumption, highlighting the potential use of this approach in characterising the relationship between past vitamin D levels and diet. …”
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Analysis of the genome data of Acinetobacter baumannii UOL-KIMZ-24, exhibiting multiple drug resistance through efflux pumpsGenebANK/NCBI. by Kiran Fatima, Syed Zeeshan Haider Naqvi, Hazrat Ali, Noor Hassan, Anam Saqib, Farheen Ansari, Sidrah Saleem, Shah Jahan, Mushtaq Ahmad

“…The assembled and annotated genome of the UOL-KIMZ-24 revealed that it has 4048631 bp genome size with 179 contigs, 38.9 % GC content, 3628 protein coding sequences, 80 tRNA and 7 rRNA. The analysis of antibiotic-resistance genes (AMR) depicted 27 genes. where the genes encoding efflux pumps such as adeABC, adeRS, adeJK, and adeMN were the more prominent. …”
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A Plasma Proteomic Approach in Rett Syndrome: Classical versus Preserved Speech Variant by Alessio Cortelazzo, Roberto Guerranti, Claudio De Felice, Cinzia Signorini, Silvia Leoncini, Alessandra Pecorelli, Claudia Landi, Luca Bini, Barbara Montomoli, Claudia Sticozzi, Lucia Ciccoli, Giuseppe Valacchi, Joussef Hayek

“…A total of five out of six (i.e., 83.3%) of the overexpressed proteins were well-known acute phase response (APR) proteins, including alpha-1-microglobulin, haptoglobin, fibrinogen beta chain, alpha-1-antitrypsin, and complement C3. …”
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A modern scientific perspective on the flavor and functional properties of diverse teas in traditional cuisine “tea-flavored fish”: From macroscopic quality to microscopic variatio... by Wenxia Wang, Kun Liu, Chunlong Liu, Bei Yang, Hao Dong, Wenzhen Liao, Xingfen Yang, Qi He

“…The results indicated that the teas preserved their sensory qualities such as texture and color, inhibited metabolic activity and microbial growth, delayed lipid oxidation and protein degradation, and inhibited biogenic amine accumulation. …”
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The role of the C5a-C5aR pathway in iron metabolism and gastric cancer progression by Qinxue Ni, Hong Yang, Hang Rao, Liyong Zhang, Mengyuan Xiong, Xiao Han, Boshao Deng, Lulu Wang, Jian Chen, Yan Shi

“…Second, it increases the expression of LCN2, a high-affinity iron-binding protein critical for iron export from tumor-associated macrophages, by activating endoplasmic reticulum stress in these cells. …”
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Investigating the ROS Formation and Particle Behavior of Food-Grade Titanium Dioxide (E171) in the TIM-1 Dynamic Gastrointestinal Digestion Model by Nicolaj S. Bischoff, Anna K. Undas, Greet van Bemmel, Jacco J. Briedé, Simone G. van Breda, Jessica Verhoeven, Sanne Verbruggen, Koen Venema, Dick T. H. M. Sijm, Theo M. de Kok

“…ROS formation was inhibited post-digestion in this cell-free environment, likely due to increased particle aggregation and protein corona formation. These findings highlight the innate potential of E171 to induce ROS and the need to consider GI digestion and food matrices in the hazard identification/characterization and risk assessment of E171.…”
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Co-modulation of a circular form of PCDH11Y during neuroendocrine differentiation of prostate cancer by Giovanni Pecoraro, Ilaria Leone, Silvia Nuzzo, Santiago Negueruela, Giovanni Smaldone, Lorena Buono

“…Functional assays demonstrated that circPCDH11Y plays a role in regulating the expression of key neuroendocrine markers, including synaptophysin (SYP), neuron-specific enolase (ENO2), prostate-specific antigen (PSA), Brain-Specific Homeobox/POU Domain Protein 2 (BRN2) and the linear form of Protocadherin 11 Y-Linked (PCDH11Y). …”
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Dexamethasone Prophylaxis in Pediatric Open Heart Surgery Is Associated with Increased Blood Long Pentraxin PTX3: Potential Clinical Implications by Franco Lerzo, Giuseppe Peri, Andrea Doni, Paola Bocca, Fabio Morandi, Angela Pistorio, Anna Maria Carleo, Alberto Mantovani, Vito Pistoia, Ignazia Prigione

“…Blood PTX3, short pentraxin C-reactive protein (CRP), interleukin-1 receptor II (IL-1RII), fibrinogen and partial thromboplastin time (PTT) were assayed at different times. …”
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Comparison of new secondgeneration H1 receptor blockers with some molecules; a study involving DFT, molecular docking, ADMET, biological target and activity by Velid Unsal, Erkan Oner, Reşit Yıldız, Başak Doğru Mert

“…The histamine-1 receptor (H1R) belongs to the family of rhodopsin-like G-protein-coupled receptors expressed in cells that mediate allergies and other pathophysiological diseases. …”
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MiR-155-Mediated Deregulation of GPER1 Plays an Important Role in the Gender Differences Related to Inflammatory Bowel Disease by Xiaojuan Shao, Jintao Li, Fumin Xu, Dongfeng Chen, Kaijun Liu

“…In IBD, microRNA-155 (miR-155) is upregulated and regulates G protein coupled estrogen receptor (GPER1), which affects the intestinal flora. …”
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