Salinity stress-induced impacts on biomass production, bioactive compounds, antioxidant activities and oxidative stress in watermeal (Wolffia globosa) by Nitesh Kumar Yadav, Arun Bhai Patel, Himanshu Priyadarshi, Sampa Baidya

“…The net biomass gain (NBG; 131.17 g), crude protein (33.16%) and crude lipid content (4.9%) were significantly high at 8.56 mM NaCl compared to control and most of other treatments. …”
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Dynamic Changes in the Nigrostriatal Pathway in the MPTP Mouse Model of Parkinson’s Disease by Dongping Huang, Jing Xu, Jinghui Wang, Jiabin Tong, Xiaochen Bai, Heng Li, Zishan Wang, Yulu Huang, Yufei Wu, Mei Yu, Fang Huang

“…Pathophysiological events, such as reductions in the striatal dopamine (DA) concentrations and levels of the tyrosine hydroxylase (TH) protein, depletion of TH-positive nerve fibers, a decrease in the number of TH-positive neurons in the substantia nigra pars compacta (SNpc), and glial activation, are addressed. …”
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Dose-dependent effects of hydroquinone on liver injury and lipid dysregulation based on SCD1/AMPK signaling pathway in C57BL/6 mice by Lijun Zou, Fen Lin, Jinying Wen, Jinyu Huang, Yue Tan, Hui Huang, Gonghua Hu

“…Notably, the mRNA or protein levels of SCD1 were upregulated in response to the lower doses of HQ (12.5 and 25.0 mg/kg), whereas AMPK activation and enhanced autophagy were observed in the 50.0 mg/kg HQ-treated group, reflecting an energy stress response. …”
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Serum cytokines in ulcerative colitis of various clinical activity by Ye. A. Konovich, I. L. Halif, M. V. Shapina, K. E. Shirokikh

“…Investigation was carried out by «Bio-Plex» protein analyzer («Bio-Rad», USA). Moderately severe and severe forms of UC were diagnosed in 15 and 18 patients respectively, mild — in 4, resistance and sensitivity for conservative treatment were detected in 15 and 22 patients. …”
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Exploring the Potential Effects of Soybean By-Product (Hulls) and Enzyme (Beta-Mannanase) on Laying Hens During Peak Production by Muhammad Shuaib, Abdul Hafeez, Deependra Paneru, Woo Kyun Kim, Muhammad Tahir, Anthony Pokoo-Aikins, Obaid Ullah, Abubakar Sufyan

“…The P1, P2, and P4 groups exhibited a significant enhancement in dry matter (<i>p</i> = 0.022) and crude fiber (<i>p</i> = 0.046) digestibility, while the P2 group demonstrated superior crude protein digestibility (<i>p</i> = 0.032), and the P1 and P2 groups showed increased crude fat digestibility compared to the other groups. …”
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Fusion to Flaviviral Leader Peptide Targets HIV-1 Reverse Transcriptase for Secretion and Reduces Its Enzymatic Activity and Ability to Induce Oxidative Stress but Has No Major Eff... by Anastasia Latanova, Stefan Petkov, Yulia Kuzmenko, Athina Kilpeläinen, Alexander Ivanov, Olga Smirnova, Olga Krotova, Sergey Korolev, Jorma Hinkula, Vadim Karpov, Maria Isaguliants, Elizaveta Starodubova

“…Inactivated multidrug-resistant RT (RT1.14opt-in) was N-terminally fused to the signal providing secretion of NS1 protein of TBEV (Ld) generating optimized inactivated Ld-carrying enzyme RT1.14oil. …”
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The study of miRNA-211 affects melanogenesis progress in Cashmere goats via suppressing <i>AP1S2</i> by B. Zhang, R. Liu, T. Ma, X. Li, Y. Zhao, H. Su, J. Li, Y. Li, H. Jiang, Q. Zhang

“…Following subcutaneous injection of antagomiRNA-211 (chemical modification inhibitor), the expression levels of the <i>AP1S2</i> gene and protein were enhanced, and the localization in the hair follicle was also increased. …”
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Effects of CO2 and liquid digestate concentrations on the growth performance and biomass composition of Tetradesmus obliquus and Chlorella vulgaris microalgal strains by Ángela Sánchez-Quintero, Ángela Sánchez-Quintero, Ángela Sánchez-Quintero, Aurélien Parsy, Amandine Adrien, Amandine Adrien, Lea Spitzer, Javier Jiménez-Lamana, Susana C. M. Fernandes, Susana C. M. Fernandes, Jean-Baptiste Beigbeder

“…The high nitrogen levels in the digestate-based medium significantly increased protein content, with 46.21% ± 3.98% dry weight (DW) for T. obliquus and 44.17% ± 2.24% DW for C. vulgaris as compared to the microalgae cultivated in commercial media. …”
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Evaluation of the Diversities in the Inflammatory Responses in Cats With Bacterial and Viral Infections by Songul Erhan, Bengu Bilgic, Ezgi Ergen, Mert Erek, Elif Ergul Ekiz, Mukaddes Ozcan, Mehmet Erman Or, Banu Dokuzeylul, Erdal Matur

“…Total and differential leukocyte counts, C‐reactive protein (CRP), transforming growth factor beta (TGF‐β), interleukin‐6 (IL‐6), tumour necrosis factor‐alpha (TNF‐α), interleukin‐1 beta (IL‐1β) and interleukin‐10 (IL‐10) concentrations were assessed in the blood samples collected from sick and healthy animals. …”
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Quercetin Alleviates Hyperglycemic-Generated Endoplasmic Reticulum Stress-Contacted Apoptosis of Rat Nucleus Pulposus Cells by Zhen Yu, Xianfeng Wang, Yusen Hu, Xinfa Wang, Zhenghuan Zhu, Xu Xu, Yiming Wang, Ailiang Zhang

“…In this research, we examined the change effect of quercetin on NP cell apoptosis, ER stress, and the protein kinase R-like ER kinase (PERK)-eukaryotic translation initiation element 2α (eIF2α)-activating transcription element 4 (ATF4). …”
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Conections between platelets amino acids profile and known cardiometabolic risk factors in patients with coronary artery disease and atrial fibrillation by I.O. Melnychuk

“…Cardiometabolic risk factors studied: total cholesterol (TC), triglycerides (TG), low-density lipoprotein (LDL), high-density lipoprotein (HDL), lipoprotein α (Lpα), apolipoprotein A1 (ApoA1), apolipoprotein B (ApoB), C-reactive protein (CRP), interleukin-6 (IL-6), trimethylamine (TMA) and trimethylamine-N-oxide (TMAO). …”
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RIPK2-Mediated Autophagy and Negatively Regulated ROS-NLRP3 Inflammasome Signaling in GMCs Stimulated with High Glucose by Chenlin Gao, Jiao Chen, Fang Fan, Yang Long, Shi Tang, Chunxia Jiang, Jiying Wang, Youhua Xu, Yong Xu

“…Hyperglycemia plays a vital role in diabetic nephropathy (DN); autophagy and its potential upregulator receptor-interacting protein kinase 2 (RIPK2) are associated with ROS, which play a potential role in regulating NLRP3, and may be involved in inflammation in DN. …”
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Targeting ferroptosis for improved radiotherapy outcomes in HPV‐negative head and neck squamous cell carcinoma by Joo Kyung Noh, Min Kyeong Lee, Yeonseo Lee, Minji Bae, Soonki Min, Moonkyoo Kong, Jung Woo Lee, Su Il Kim, Young Chan Lee, Seong‐Gyu Ko, Seon Rang Woo, Young‐Gyu Eun

“…Subtype B of the FRGS, characterized by decreased expression of ferroptosis inducers [nuclear receptor coactivator 4 (NCOA4) and natural resistance‐associated macrophage protein 2 homolog/divalent metal transporter 1 (NRAMP2/DMT1)] and increased expression of suppressors [phospholipid hydroperoxide glutathione peroxidase (GPX4) and ferritin heavy chain (FTH1)], was associated with poorer prognosis, potentially indicating the inhibition of ferroptosis. …”
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Prenatal inflammation impairs early CD11c-positive microglia induction and delays myelination in neurodevelopmental disorders by Kazuya Fuma, Yukako Iitani, Kenji Imai, Takafumi Ushida, Sho Tano, Kosuke Yoshida, Akira Yokoi, Rika Miki, Hiroyuki Kidokoro, Yoshiaki Sato, Yuichiro Hara, Tomoo Ogi, Kohei Nomaki, Makoto Tsuda, Okiru Komine, Koji Yamanaka, Hiroaki Kajiyama, Tomomi Kotani

“…Furthermore, myelination-related protein levels significantly decreased in the MIA group at PN8d. …”
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Predicting Poor Outcome of COVID-19 Patients on the Day of Admission with the COVID-19 Score by Luke Tseng, Erin Hittesdorf, Mitchell F. Berman, Desmond A. Jordan, Nina Yoh, Katerina Elisman, Katherine A. Eiseman, Yuqi Miao, Shuang Wang, Gebhard Wagener

“…The final multivariate model included age, albumin, creatinine, C-reactive protein, and lactate dehydrogenase. The area under the ROC curve was 0.850 (CI [95%]: 0.813, 0.889), with a sensitivity of 0.800 and specificity of 0.761. …”
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Are Trace Elements Provided for Children on Long-Term Parenteral Nutrition Adequate to Meet Their Needs? by Hanna Romanowska, Mikołaj Danko, Anna Borkowska, Katarzyna Popińska, Marta Sibilska, Joanna Żydak, Joanna Wielopolska, Klaudia Bartoszewicz, Agnieszka Szlagatys-Sidorkiewicz, Janusz Książyk

“…Children with signs of infection or elevated C-reactive protein levels were excluded. Elemental analysis was performed using inductively coupled plasma mass spectrometry (ICP-MS). …”
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SCN10A gene polymorphism is associated with pain sensitivity and postoperative analgesic effects in patients undergoing gynecological laparoscopy by Yang Gao, Jing Li, Lin Gan, Meng Cai, Xiaofeng Lei, Jin Yu

“…The SCN10A gene encodes the Nav1.8 sodium channel protein, which is crucial for pain signal transmission in peripheral sensory neurons. …”
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Serum Ferritin Levels in Pregnancy and Their Association with Gestational Diabetes Mellitus: A Prospective Longitudinal Study by Qin Z, Du Y, Wang Z, Qin X, Wu H, Yu X, Zhao C, Mo L, Huang B

“…We measured SF levels in the1st, 2nd, and 3rd trimesters, as well as plasma malondialdehyde (MDA) and C-reactive protein (CRP) in the 1st trimester, blood glucose levels in the oral glucose tolerance test (OGTT), and glycosylated hemoglobin (HbA1c) in the 2nd trimester. …”
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ERK1/2 Inhibition Alleviates Diabetic Cardiomyopathy by Suppressing Fatty Acid Metabolism by Erin McLean, Caroline De Roo, Annabel Maag, Megan Coble, Jefferson Cano, Ruijie Liu

“…Extracellular signal-regulated protein kinases 1 and 2 (ERK1/2) have been implicated in the metabolism of fatty acids in the liver and skeletal muscles. …”
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Efficacy and retention rate of secukinumab in psoriatic arthritis across different clinical phenotypes: insights from the Italian GISEA Registry by Giuseppe Lopalco, Maria Morrone, Fabiola Atzeni, Chiara Bazzani, Francesco Paolo Bianchi, Francesco Paolo Cantatore, Roberto Caporali, Antonio Carletto, Alberto Cauli, Maria Sole Chimenti, Sergio Colella, Fabrizio Conti, Addolorata Corrado, Ennio Giulio Favalli, Alberto Floris, Marco Fornaro, Rosario Foti, Roberta Foti, Elena Fracassi, Bruno Frediani, Stefano Gentileschi, Roberto Gorla, Elisa Gremese, Emanuela Praino, Roberta Ramonda, Cinzia Rotondo, Marco Sebastiani, Angelo Semeraro, Gianfranco Ferraccioli, Giovanni Lapadula, Florenzo Iannone

“…Clinical outcomes, including Disease Activity Index for Psoriatic Arthritis (DAPSA), Psoriasis Area Severity Index (PASI), Ankylosing Spondylitis Disease Activity Score (ASDAS, C-Reactive Protein (CRP)-based), and Visual Analogue Scale (VAS) measures, were evaluated at baseline and at 6, 12, and 24 months. …”
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