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11661
Sex differences in the neuroinflammatory signaling pathway: effect of miRNAs on fatty acid synthesis in microglia
Published 2025-02-01“…Following testosterone treatment, miRNA, gene, and protein expression levels were investigated. An inflammatory response was induced using lipopolysaccharide (LPS) stimulation, and subsequent p65 phosphorylation was assessed. …”
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11662
A pan-cancer analysis: predictive role of ZNF32 in cancer prognosis and immunotherapy response
Published 2025-01-01“…Abstract The zinc finger protein 32 (ZNF32) has been associated with high expression in various cancers, underscoring its significant function in both cancer biology and immune response. …”
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11663
The small GTPases FoRab5, FoRab7, and FoRab8 regulate vesicle transport to modulate vegetative development and pathogenicity in Fusarium oxysporum f. sp. conglutinans
Published 2025-01-01“…In this study, we examined the three proteins FoRab5, FoRab7, and FoRab8 of Foc, which exhibit homology to the Rab protein family found in Saccharomyces cerevisiae. …”
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11664
Genes related to neural tube defects and glioblastoma
Published 2025-01-01“…Our results indicated that two genes at mRNA and protein levels have been well verified in both NTDs mouse and GBM human samples, namely, Poli and Fgf1. …”
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11665
Autoinflammatory diseases. Part 1: concept, classification, immunobiology, diagnosis
Published 2024-11-01“…In particular, we review how the innate immune system triggers inflammation within the inflammasome, interferon and nuclear factor kappa B (NF-κB) signaling pathways, highlighting the role of intracellular sensor proteins, inflammasomes, gasdermin D, IL-1β, IL-18 and IL-36, NF-κB, tumor necrosis factor, type 1 interferons, and others. …”
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11666
Isolation and Characterization of the Physiochemical Properties of Brewer’s Spent Grain
Published 2024-12-01“…Standard proximate analyses showed that Hemi. A has the highest protein (66 wt.%), which can be utilized as a renewable solid-state N-precursor as dopants during the thermochemical conversion process. …”
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11667
Relationship between Obesity and Cognitive Function in Young Women: The Food, Mood and Mind Study
Published 2017-01-01“…Questionnaires on depression and physical activity and a fasting blood sample for C-reactive protein and the Omega-3 Index were also collected. …”
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11668
Expression Profiling Using a cDNA Array and Immunohistochemistry for the Extracellular Matrix Genes FN-1, ITGA-3, ITGB-5, MMP-2, and MMP-9 in Colorectal Carcinoma Progression and D...
Published 2014-01-01“…This investigation intended to evaluate the association between FN-1, ITGA-3, ITGB-5, MMP-2, and MMP-9 gene and protein expression levels in tumor tissue with clinical and histopathological neoplastic parameters of cancer dissemination. …”
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11669
Phylogenomic analysis reveals exceptions to the co-evolution of ZAR1 and ZRK immune gene families in plants
Published 2025-01-01“…Abstract Background HOPZ-ACTIVATED RESISTANCE 1 (ZAR1) is a nucleotide-binding leucine-rich repeat (NLR) protein functioning as a recognition hub to initiate effector-triggered immunity against bacterial pathogens. …”
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11670
Boanmycin overcomes bortezomib resistance by inducing DNA damage and endoplasmic reticulum functional impairment in multiple myeloma
Published 2025-01-01“…The viability of MM cell lines and patient bone marrow mononuclear cells (BMMCs) was measured via the CCK8 reagent. The protein levels of cleaved caspase 3, cleaved caspase 7, cleaved PARP, PARP, p-JNK, JNK, and γ-H2AX were analyzed through Western blot. …”
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11671
NEW MID-SEASON SPRING BARLEY CULTIVAR OMSKY 101
Published 2019-10-01“…Also, when compared with both the reference and ‘Omsky 100’, there was an increased content of protein (+1.0 and +0.9%, respectively) and starch (+1.3 and +1.5%, respectively) in grain. …”
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11672
A genetic exploration of the relationship between posttraumatic stress disorder and cardiovascular diseases
Published 2025-01-01“…Insomnia, smoking, alcohol dependence, waist-to-hip ratio, and inflammation (IL6, C-reactive protein) partly mediated these associations. Mendelian randomization indicated that PTSD causally increases CAD (IVW OR = 1.53, 95% CIs = 1.19-1.96, p = 0.001), HF (OR = 1.44, CIs = 1.08-1.92, p = 0.012), and to a lesser degree HT (OR = 1.25, CIs = 1.05-1.49, p = 0.012). …”
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11673
Lactoferrin Decreases the Intestinal Inflammation Triggered by a Soybean Meal-Based Diet in Zebrafish
Published 2016-01-01“…Due to the positive costs-benefits ratio of including soybean meal in farmed fish diets, identifying additives with intestinal anti-inflammatory effects could contribute to solving the issues caused by this plant protein. This study evaluated the effect of incorporating lactoferrin (LF) into a soybean meal-based diet on intestinal inflammation in zebrafish. …”
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11674
The Treg/Th17 Imbalance in Patients with Obstructive Sleep Apnoea Syndrome
Published 2012-01-01“…Furthermore, the Th17/Treg ratio was positively related to the severity of OSAS and serum levels of C-reactive protein. The development of OSAS may be associated with peripheral Th17/Treg imbalance and characterized by a proinflammatory cytokine microenvironment. …”
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11675
Does gender influence outcome measures similarly in patients with spondyloarthritis? Results from the ASAS-perSpA study
Published 2022-09-01“…Associations between gender and disease activity (Ankylosing Spondylitis Disease Activity Score (ASDAS), Bath Ankylosing Spondylitis Disease Activity Score (BASDAI), C-reactive protein (CRP)), function (Bath Ankylosing Spondylitis Functional Index (BASFI)) and overall health (ASAS Health Index (ASAS HI), European Quality of Life Five Dimension (EQ-5D)) outcomes were investigated. …”
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11676
Exosomes derived from hUC-MSCs exhibit ameliorative efficacy upon previous cesarean scar defect via orchestrating β-TrCP/CHK1 axis
Published 2025-01-01“…., histopathological sections, qRT-PCR assay, western-blotting analysis, Co-IP assay, protein degradation and ubiquitination), we further dissected the underlying regulatory mechanism. …”
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11677
TRAIL and Ceruloplasmin Inverse Correlation as a Representative Crosstalk between Inflammation and Oxidative Stress
Published 2018-01-01“…After stratification for high-sensitivity C-reactive protein levels, the inverse association between TRAIL and ceruloplasmin levels remained strong and significant (r=−0.508, p<0.001, R2=0.260) only in the presence of inflammation, confirming the role of inflammation as emerged in in vitro experiments where recombinant TRAIL decreased ceruloplasmin expression levels in TNF-treated PBMC cultures. …”
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11678
Leukopenia and thrombocytopenia in dengue patients presenting in the emergency department of a tertiary center in Nepal: a cross-sectional study
Published 2025-01-01“…Methods A cross-sectional study was conducted among 252 patients with dengue confirmed by serological testing against dengue-specific nonstructural protein 1 (NS1) antigen and immunoglobulin M (IgM) by enzyme-linked immunosorbent assay from September to November 2022 who presented in the emergency department of a tertiary hospital in Nepal after ethical approval was obtained. …”
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11679
Adrenal (Pro)renin Receptor Expression and Serum Soluble (Pro)renin Receptor Concentration in Primary Aldosteronism
Published 2020-01-01“…The (pro)renin receptor [(P)RR] is a multifunctioning protein playing roles in various pathological conditions. …”
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11680
Oral Health Impact Profile in Celiac Patients: Analysis of Recent Findings in a Literature Review
Published 2018-01-01“…Gluten is a proline-rich and glutamine-rich protein present in wheat (gliadin), barley (hordein), and rye (secalin). …”
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