Assessment of immune responses and intestinal flora in BALB/c mice model of wheat food allergy via different sensitization methods by Chenglong Liu, Chen Chen, Xingyu Yan, Shimin Gu, Xin Jia, Wenhui Fu, Xiao Meng, Wentong Xue

“…The results showed that the abundance of Firmicutes in the wheat protein sensitized group was lower than that in the normal group, while the abundance of Bacteroidetes was higher, and Lactobacillus was the difference marker in normal group. …”
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Anti-TNF-Mediated Modulation of Prohepcidin Improves Iron Availability in Inflammatory Bowel Disease, in an IL-6-Mediated Fashion by Flaminia Cavallaro, Lorena Duca, Laura Francesca Pisani, Roberta Rigolini, Luisa Spina, Gian Eugenio Tontini, Nadia Munizio, Elena Costa, Maria Domenica Cappellini, Maurizio Vecchi, Luca Pastorelli

“…Prohepcidin, erythropoietin, erythroferrone, C reactive protein, interleukin-6, iron markers, and haemoglobin levels were measured and clinical activity indexes were evaluated. …”
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Fecal and Salivary Cortisol Concentrations in Woolly (Lagothrix ssp.) and Spider Monkeys (Ateles spp.) by Kimberly D. Ange-van Heugten, Eric van Heugten, Saskia Timmer, Guido Bosch, Abahor Elias, Scott Whisnant, Hans J. M. Swarts, Peter Ferket, Martin W. A. Verstegen

“…Cortisol was highest for zoos that did not meet crude protein requirements and fed the lowest percentage of complete feeds and crude fiber. …”
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Pharmacological Mechanism of Zuojin Pill for Gastroesophageal Reflux Disease: A Network Pharmacology Study by Mi Lv, Jinke Huang, Jiayan Hu, Wenxi Yu, Ping Liu, Kunli Zhang, Fengyun Wang

“…Finally, the prediction results of NP were validated by MD, and MDS of the optimal core protein-ligand for each component obtained by MD were performed using Gromacs 2020 software. …”
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IL-13 Augments Histone Demethylase JMJD2B/KDM4B Expression Levels, Activity, and Nuclear Translocation in Airway Fibroblasts in Asthma by Khuloud Bajbouj, Mahmood Y. Hachim, Rakhee K. Ramakrishnan, Huwaida Fazel, Jumana Mustafa, Shahed Alzaghari, Mahmoud Eladl, Jasmin Shafarin, Ronald Olivenstein, Qutayba Hamid

“…Bronchial fibroblasts isolated from healthy and asthmatic individuals were assessed for the gene and protein expression levels of the identified gene at baseline and upon IL-13 treatment using qRT-PCR and western blotting, respectively. …”
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Associations between Autoimmunity and Depression: Serum IL-6 and IL-17 Have Directly Impact on the HAMD Scores in Patients with First-Episode Depressive Disorder by Lijuan Mao, Xiajin Ren, Xin Wang, Feng Tian

“…Before treatment, the IL-6 (28.99±5.51, P<0.001) and IL-17 (41.15±4.80, P<0.001) in the FDD group were significantly higher than the control group (16.84±3.78 and 21.68±3.72, respectively). The C-reactive protein (CRP) level in two groups was comparable (P=0.879). …”
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Deteksi Kesegaran Ikan Tongkol (Euthynnus Affinis) secara Otomatis Berdasarkan Citra Mata Menggunakan Binary Similarity by Hurriyatul Fitriyah, Dahnial Syauqy, Faizal Andy Susilo

“…Abstract Tongkol fish (Euthynnus Affinis) is one of the most popular fish in Indonesia because it has more protein than tuna, but with a relatively cheaper price. …”
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Associations between inflammation and striatal dopamine D2-receptor availability in aging by Vanessa Crine, Goran Papenberg, Jarkko Johansson, Carl-Johan Boraxbekk, Anders Wåhlin, Ulman Lindenberger, Martin Lövdén, Katrine Riklund, Lars Bäckman, Lars Nyberg, Nina Karalija

“…Inflammation was assessed by two C-reactive protein-associated DNA methylation scores at study baseline. …”
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Inhibitory Effects of a Novel PPAR-γ Agonist MEKT1 on Pomc Expression/ACTH Secretion in AtT20 Cells by Rehana Parvin, Erika Noro, Akiko Saito-Hakoda, Hiroki Shimada, Susumu Suzuki, Kyoko Shimizu, Hiroyuki Miyachi, Atsushi Yokoyama, Akira Sugawara

“…MEKT1 also was demonstrated to inhibit the protein-DNA interaction of Nur77/Nurr1-NurRE, Tpit-TpitRE, and Nur77-NBRE by ChIP assay. …”
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Masticatory muscle changes on magnetic resonance imaging of dogs with Neospora caninum compared to meningoencephalitis of unknown origin by Jessica Zilli, Kathryn Fleming, Chloe Fisher, Chloe Fisher, Tim Sparks, Tom Harcourt-Brown, Edward Ives

“…Within the neosporosis group, dogs with masticatory muscle lesions had significantly higher cerebrospinal fluid WBC counts (p = 0.017) and protein concentrations (p = 0.025) compared to those without muscle changes. …”
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A high-fidelity CRISPR-Cas13 system improves abnormalities associated with C9ORF72-linked ALS/FTD by Tristan X. McCallister, Colin K. W. Lim, Mayuri Singh, Sijia Zhang, Najah S. Ahsan, William M. Terpstra, Alisha Y. Xiong, M. Alejandra Zeballos C, Jackson E. Powell, Jenny Drnevich, Yifei Kang, Thomas Gaj

“…When delivered to the brain of a transgenic rodent model, this Cas13-based platform curbed the expression of the G4C2 repeat-containing RNA without affecting normal C9ORF72 levels, which in turn decreased the formation of RNA foci, reduced the production of a dipeptide repeat protein, and reversed transcriptional deficits. This high-fidelity system possessed improved transcriptome-wide specificity compared to its native form and mediated targeting in motor neuron-like cells derived from a patient with ALS. …”
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Investigating the Role of Osteopontin (OPN) in the Progression of Breast, Prostate, Renal and Skin Cancers by Gautam Kundu, Selvakumar Elangovan

“…These effects are primarily caused by the upregulation of oncogenes, of which SPP1 (secreted phosphoprotein 1), a non-collagenous bone matrix protein, is one of the most well-known. <b>Methods</b>: In this study, we conducted a further examination of the transcriptomic expression profile of SPP1 (Osteopontin) during the progression of cancer in four human tissues, breast, prostate, renal and skin, in order to understand the circumstances conducive to its activation and dysregulation, the biological pathways and other mechanisms involved as well as differences in its splicing patterns influencing its expression and functionality. …”
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Antimicrobial resistance in wild game mammals: a glimpse into the contamination of wild habitats in a systematic review and meta-analysis by Claire Julie Akwongo, Luca Borrelli, Kurt Houf, Alessandro Fioretti, Maria Francesca Peruzy, Nicoletta Murru

“…Abstract Background Wild game meat has over the years gained popularity across the globe as it is considered a food source with high protein content, low fat content, and a balanced composition of fatty acids and minerals, which are requirements for a healthy diet. …”
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Plasma Fatty Acids in Zambian Adults with HIV/AIDS: Relation to Dietary Intake and Cardiovascular Risk Factors by Christopher K. Nyirenda, Edmond K. Kabagambe, John R. Koethe, James N. Kiage, Benjamin H. Chi, Patrick Musonda, Meridith Blevins, Claire N. Bosire, Michael Y. Tsai, Douglas C. Heimburger

“…While there were no significant associations (p>0.05) between total plasma PUFA and C-reactive protein (CRP) or lipid levels, plasma arachidonic acid was inversely associated with CRP and triglycerides and positively associated with HDL-C, CD4+ T-cell count, and plasma albumin (p<0.05). …”
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Passive infusion of an S2-Stem broadly neutralizing antibody protects against SARS-CoV-2 infection and lower airway inflammation in rhesus macaques. by Christopher T Edwards, Kirti A Karunakaran, Elijah Garcia, Nathan Beutler, Matthew Gagne, Nadia Golden, Hadj Aoued, Kathryn L Pellegrini, Matthew R Burnett, Christopher Cole Honeycutt, Stacey A Lapp, Thang Ton, Mark C Lin, Amanda Metz, Andrei Bombin, Kelly Goff, Sarah E Scheuermann, Amelia Wilkes, Jennifer S Wood, Stephanie Ehnert, Stacey Weissman, Elizabeth H Curran, Melissa Roy, Evan Dessasau, Mirko Paiardini, Amit A Upadhyay, Ian N Moore, Nicholas J Maness, Daniel C Douek, Anne Piantadosi, Raiees Andrabi, Thomas R Rogers, Dennis R Burton, Steven E Bosinger

“…Many of these mAbs target the conserved S2 stem region of the SARS-CoV-2 spike protein, rather than the receptor binding domain contained within S1 primarily targeted by current SARS-CoV-2 vaccines. …”
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Evaluation of cellular and physiological alterations of cells from Mytilus galloprovincialis exposed to benzisothiazolinone by Federica Impellitteri, Kristian Riolo, Giorgia Zicarelli, Miriam Porretti, Cristiana Roberta Multisanti, Giuseppe Piccione, Alessia Giannetto, Caterina Faggio

“…The most significant results obtained from these tests were the reduction of viability of haemocytes at T2 of exposure to B2, a decrease of vitality in DG cells exposed to B1 during the T1, the significant alteration in the phagocytosis activity, the upregulation of Cu/ZnSOD gene, the inhibition of the CYPY1 gene expression and upregulation of the Heat shock protein 70 (Hsp70) gene following the BIT exposure. …”
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Production of a new variant of soluble trimer Env of HIV-1 CRF63_02A6 SOSIP.664 by Nadezhda B. Rudometova, Andrey P. Rudometov, Anastasia A. Fando, Danil I. Vahitov, Alexander A. Ilyichev, Alexander P. Agafonov, Larisa I. Karpenko

“…A stable producer of trimer Env was obtained by transfection of the CHO-K1 cell line using the developed plasmid vector. Purification of the protein complex was performed using affinity chromatography and gel filtration. …”
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Analysis of the MYB gene family in tartary buckwheat and functional investigation of FtPinG0005108900.01 in response to drought by Jinbo Li, Xin Yang, Bianling Tian, Tian Tian, Yu Meng, Fei Liu

“…FtMYB gene FtPinG0005108900.01 were shown to activated by PEG6000 and natural drought treatment, and its encoded protein localizes to nucleus, revealing it as a typical transcription factor. …”
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Jiangzhi Granule Ameliorates JNK-Mediated Mitochondrial Dysfunction to Reduce Lipotoxic Liver Injury in NASH by Jiang Y, Xu J, Ding J, Liu T, Liu Y, Huang P, Wang Q, Zheng P, Song H, Yang L

“…Additionally, elevated phosphorylation ratio of non-receptor tyrosine kinase c-Src (Src) and reduced phosphorylation ratio of JNK and SH2-containing protein tyrosine phosphatase (SHP-1) were found in both hepatocytes and mice liver tissues treated with JZG versus those with the vehicle.Conclusion: Taken together, JZG could improve mitochondrial dysfunction and reduce lipotoxic liver injury in NASH in vivo and in vitro models. …”
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The demographic history of the wild crop relative Brachypodium distachyon is shaped by distinct past and present ecological niches by Minadakis, Nikolaos, Williams, Hefin, Horvath, Robert, Caković, Danka, Stritt, Christoph, Thieme, Michael, Bourgeois, Yann, Roulin, Anne C.

“…Given that grasses also supply about a fifth of the world's dietary protein as cereal grains, unlocking the sources of phenotypic variation in B. distachyon is hence of prime interest in fundamental and applied research in agronomy, ecology and evolution. …”
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