Anti-allergic potentials of Ceriops decandra leaves in TDI-induced allergic mice: Comprehensive in-vivo and in-silico studies by Aishwarja Dey, Subarna Rani, Rabindra Nath Acharyya, Apurba Kumar Barman, Khondoker Shahin Ahmed, Nripendra Nath Biswas, Shrabanti Dev, Asish Kumar Das

“…Among those Rutin hydrate, exhibited the best docking scores at all the targeted protein molecules and the highest binding affinity was (-9.8 kcal/mol) against Interleukin-5. …”
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Flavocoxid, a Nutraceutical Approach to Blunt Inflammatory Conditions by Alessandra Bitto, Francesco Squadrito, Natasha Irrera, Gabriele Pizzino, Giovanni Pallio, Anna Mecchio, Federica Galfo, Domenica Altavilla

“…Flavocoxid downregulates gene or protein expression of several inflammatory markers and exerts also strong antioxidant activity in several experimental models. …”
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Inclusion of Saccharomyces cerevisiae var. boulardii RC009 and Pediococcus pentosaceus RC007 as a Probiotic Additive in Pigs’ Postweaning Diets and Its Effect on Meat Composition,... by J. Parada, A. Magnoli, V. Alonso, L. Diaz Vergara, M. Corti Isgro, J. J. T. Posse, M. A. Montenegro, L. Cavaglieri

“…Analyses of carcass composition, muscle depth, protein content, total fat and ash, drip and cooking water loss, and fatty acids were performed. …”
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Targeted therapy and immunotherapy for gastric cancer: rational strategies, novel advancements, challenges, and future perspectives by Dong Luo, Yunmei Liu, Zhengmao Lu, Lei Huang

“…Programmed cell death protein 1 (PD-1) and programmed cell death-ligand 1 (PD-L1) antibodies are the most commonly used immunotherapeutic agents and have been used with some success in GC treatment. …”
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Viral RNA polymerase as a SUMOylation decoy inhibits RNA quality control to promote potyvirus infection by Linhao Ge, Mingxuan Jia, Hongying Shan, Weifang Gao, Lu Jiang, Hongguang Cui, Xiaofei Cheng, Marilyne Uzest, Xueping Zhou, Aiming Wang, Fangfang Li

“…These two SIMs are conserved among the majority of potyvirids-encoded NIbs. Thus, virus protein-mediated SUMOylation decoy strategy to suppress host defense may be a common feature in plant virus pathosystems. …”
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Artesunate, EDTA, and colistin work synergistically against MCR-negative and -positive colistin-resistant Salmonella by Yajun Zhai, Peiyi Liu, Xueqin Hu, Changjian Fan, Xiaodie Cui, Qibiao He, Dandan He, Xiaoyuan Ma, Gongzheng Hu

“…Additionally, we also demonstrated that the CheA of chemosensory system and virulence-related protein SpvD were critical for the bacteriostatic synergistic effects of the triple combination. …”
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miR-149 Alleviates Ox-LDL-Induced Endothelial Cell Injury by Promoting Autophagy through Akt/mTOR Pathway by Zhongsheng Zhu, Jinyu Li, Rui Tong, Xiaorong Zhang, Bo Yu

“…RT-qPCR and western blot were carried out to determine the mRNA and protein expressions of Akt and mTOR. Results. The miR-149 level in HUVECs was reduced by ox-LDL (100 μg/mL) incubation in a time-dependent manner. miR-149-mimic transfection markedly protected HUVECs from ox-LDL-induced injury, with increased cell viability and reduced caspase-3 activity. miR-149 mimics enhanced HUVEC autophagy, which was induced initially by ox-LDL. miR-149 mimics also markedly downregulated the expression of Akt, p-Akt, mTOR, and p-mTOR in ox-LDL-treated HUVECs. …”
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Cytokine and Chemokine Responses of Peripheral Blood Mononuclear Cells from Dogs Infected with <i>Mycobacterium bovis</i> by Tyler Morrison, Danielle A. Gunn-Moore, Jayne C. Hope, Conor O’Halloran

“…Serum samples were tested to further classify dogs as seropositive or seronegative for circulating antibodies against <i>M. bovis</i> using the DPP^® VetTB Assay, Idexx <i>M. bovis</i> antibody ELISA, and a novel purified protein derivative ELISA. Isolated PBMCs were stimulated with mycobacterial proteins (PPDB or ESAT-6/CFP-10), and 13 cytokines/chemokines were measured in the supernatant. …”
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Analysis of factors affecting the clinical management of infection in culture-negative patients following percutaneous endoscopic decompression: a retrospective study by Changpeng Qu, Haixin Wei, Hao Zhang, Zheng Lian, Hui Lu, Shuo Han

“…Patient demographics, hidden blood loss, daily blood glucose control, and maximum temperature during treatment were recorded as potential risk factors. C-reactive protein, procalcitonin, white blood cells, erythrocyte sedimentation rate, and the duration of antibiotic treatment were used as indicators of infection treatment. …”
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Melatonin Promotes Yield Increase in Wheat by Regulating Its Antioxidant System and Growth Under Drought Stress by Xue Li, Jia Liu, Cuiping Zhang, Ze Liu, Xiang Guo, Shaoxiang Li, Hongsheng Li, Kun Liu, Kunzhi Li, Mingliang Ding

“…In contrast to the control, 100 or 200 µM melatonin seed coating significantly raised the contents of soluble protein and chlorophyll in wheat seedlings. Further studies demonstrated that 100 µM melatonin seed coating promoted the increase in the thousand-grain weight and yield of wheat under drought stress. …”
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Nutritional Quality and Safety of Complementary Foods Developed from Blends of Staple Grains and Honey Bee Larvae (Apis mellifera) by Shewangzaw Addisu Mekuria, John N. Kinyuru, Beatrice Kiage Mokua, Mesfin Wogayehu Tenagashaw

“…ComF02 recorded the highest fat content (14.3 g/100 g), energy (427.18 kcal/100 g), and vitamins A (706 μg/100 g), B3 (8.2 mg/100 g), and B9 (86.7 mg/100 g) while ComF01 had the highest protein content (12.56 g/100 g). Iron (40.94 mg/100 g) and calcium (68.20 mg/100 g) were the minerals with the highest content in ComF02. …”
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Identification of the Bovine <i>CSN3</i> Core Promoter Region and the Relationships Between <i>CSN3</i> Promoter Polymorphisms and the <i>CSN3</i> A and B Alleles by Wenqing Li, Xiaoyang Wang, Xiuyang Xu, Pinhui Wu, Tong Fu, Liyang Zhang, Tengyun Gao

“…Reportedly, the number of κ-casein (κ-CN) B alleles increases the proportion of κ-CN to total protein and the κ-CN content. This phenomenon is caused by single-nucleotide polymorphisms (SNPs) in the promoter region of <i>CSN3</i>, which encodes the B variant. …”
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New Insights Into Hepatic Impairment (HI) Trials by Sebastian Haertter, Maximilian Lobmeyer, Brian C. Ferslew, Pallabi Mitra, Thomas Arnhold

“…Compounds demonstrating a steep increase typically had a high plasma protein binding of > 95%, high volume of distribution, lower absolute bioavailability, minor elimination via the kidneys, were predominantly metabolized by CYP3A4 or CYP2D6 and the majority of these compounds were substrates of OATP1B1. …”
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Changes in tear cytokine and lactoferrin levels in postmenopausal women with primary acquired nasolacrimal duct obstruction complicated with obstructed meibomian gland dysfunction by Haili Jin, Xianjie Chen, Feng Ji, Yin Liu, Yonghong Sheng, Guoping Wang, Linfeng Han, Xiaohu Wang, He Ding, Jing Liu, Qingqing Fu

“…Results In the PANDO with OMGD group, the IL-8, IL-1α, IL-1β, and macrophage inflammatory protein-1α levels were significantly higher than those in the other groups. …”
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Dengue Virus Infection Causes the Activation of Distinct NF-κB Pathways for Inducible Nitric Oxide Synthase and TNF-α Expression in RAW264.7 Cells by Yi-Lin Cheng, Yee-Shin Lin, Chia-Ling Chen, Shu-Wen Wan, Yi-Dan Ou, Chia-Yi Yu, Tsung-Ting Tsai, Po-Chun Tseng, Chiou-Feng Lin

“…In contrast to TLR3, viral protein NS2B3 also independently contributed to NF-κB activation to regulate TNF-α production. …”
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The Transcription Factor SOX18 Inhibitor Small Molecule 4 Is a Potential Treatment of Cancer‐Induced Lymphatic Metastasis and Lymphangiosarcoma by Katja K. Koll, Martin M. Zimmermann, Patrick A. Will, Ulrich Kneser, Christoph Hirche

“…Sm4 treatment decreased the Sox18 expression level at the mRNA and protein levels in both HDLEC and MO‐LAS significantly, a phenomenon confirmed through immunofluorescence images. …”
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Unveiling the mechanism of micro-and-nano plastic phytotoxicity on terrestrial plants: A comprehensive review of omics approaches by Asad Jamil, Ambreen Ahmad, Muhammad Moeen-ud-din, Yihao Zhang, Yuxuan Zhao, Xiaochen Chen, Xiaoyu Cui, Yindong Tong, Xianhua Liu

“…This literature review synthesizes current findings regarding MNPs-induced phytotoxicity, emphasizing alterations in gene expression, protein synthesis, metabolic pathways, and physiological disruptions as revealed through omics analyses. …”
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THE DIETARY PATTERNS AND THE RISK OF BREAST CANCER by L. A. Radkevich, D. A. Radkevich

“…The power structure of countries were represented in the form of a total daily level of consumption (DLC) (g/person/day), and also in the form of blocks of products with common source of origin (g/person/day): animal products, grains, vegetables”, “fruit drinks”, “alcoholic beverages”; “nutrients of animal products” (%): energy, protein, fat; “full of nutrients” (%): carbohydrates, proteins, fats; energy (kcal/person/day), proteins and fats (g/person/day). …”
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Generation and analysis of mouse embryonic stem cells with knockout of the <i>Mcph1</i> (microcephalin) gene by A. M. Yunusova, A. V. Smirnov, T. A. Shnaider, I. E. Pristyazhnuk, S. Y. Korableva, N. R. Battulin

“…Сohesin and condensins are conserved multi-subunit protein complexes that participate in mammalian genome organization by extruding chromatin loops. …”
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Biochemical and Histopathological Studies of Key Tissues in Healthy Male Wistar Rats Fed on African Yam Bean Seed and Tuber Meals by Omena Bernard Ojuederie, John Adebayo Ajiboye, Olubukola Oluranti Babalola

“…The consumption of 100% unprocessed AYB seeds caused liver and kidney damage in rats due to increased levels of aspartate aminotransferase (5.04 ± 1.62 U L−I), alanine aminotransferase (8.46 ± 2.43 U L−I), and lipid peroxidation (0.27 ± 0.02-unit mg−1protein). AYB tubers were innocuous to Wistar rats investigated. …”
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