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10561
Genome-wide identification, characterization and expression pattern analysis of HAK/KUP/KT potassium transporter gene family in potato
Published 2025-01-01“…Based on phylogenetic analysis, these StHAK gene family members were classified into four distinct clusters. All StHAK protein sequences contained the conserved motifs and domains. …”
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10562
Association of ATP-Binding Cassette Transporter A1 Gene Polymorphisms in Type 2 Diabetes Mellitus among Malaysians
Published 2015-01-01“…Type 2 diabetes mellitus (T2DM) is a complex polygenic disorder characterized by impaired insulin resistance, insulin secretion, and dysregulation of lipid and protein metabolism with environmental and genetic factors. …”
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10563
Age-related aspects of glioma: current understanding. Literature review
Published 2024-12-01“…Additionally, changes in histone proteins H3.3 or 3.1 (H3.3 K27 and H3 G34) in pHGG, as opposed to aHGG, carry diagnostic and prognostic significance. …”
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10564
Establishment of a rapid method for the detection of Brucella canis based on recombinase-mediated thermostable nucleic acid amplification technology
Published 2025-01-01“…ObjectiveTo establish a rapid detection method for canine brucellosis using recombinase-aided amplification (RAA) technology.MethodsThe outer membrane protein 25 gene fragment (Omp25) of Brucella canis was targeted. …”
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10565
Organoleptic, physical, and chemical tests of artificial feed for milk fish substituted by earthworm meal (Lumbricus sp.)
Published 2013-11-01“…The quality of feed is chemically with moisture content ranging from 8,4–9,1%, 16,7–19,46% ash, 31,07–32,37%, protein, 6,67–7,58% fat, crude fiber 7,45–7,87%, NFE (nitrogen free extracts) 35,35–35,48%. …”
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10566
Physiological and Biochemical Responses of Ulva prolifera and Ulva linza to Cadmium Stress
Published 2013-01-01“…A range of parameters (concentrations of cadmium, Ca2+, N, P, K+, Cl−, free amino acids (FAAs), proline, organic acids and soluble protein, Fv/Fm, Yield, OAA, and K+/Na+) could be used to evaluate cadmium resistance in Ulva by correlation analysis. …”
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10567
Exploring the Therapeutic Potential of Cannabidiol in U87MG Cells: Effects on Autophagy and NRF2 Pathway
Published 2024-12-01“…Due to mitochondria functionality alteration, pro-apoptotic proteins were induced without activating apoptotic effectors Caspase-3 or Caspase-7. …”
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10568
Alzheimer-mutant γ-secretase complexes stall amyloid β-peptide production
Published 2025-02-01“…Missense mutations in the amyloid precursor protein (APP) and presenilin-1 (PSEN1) cause early-onset familial Alzheimer’s disease (FAD) and alter proteolytic production of secreted 38-to-43-residue amyloid β-peptides (Aβ) by the PSEN1-containing γ-secretase complex, ostensibly supporting the amyloid hypothesis of pathogenesis. …”
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10569
Relationship between inherited genetic variation and survival from colorectal cancer stratified by tumour location
Published 2025-01-01“…We investigated the relationship between Phosphatidylinositol 4-Kinase Type 2 Beta (PI4K2B) expression in colorectal tumours and survival in 597 patients from The Human Protein Atlas (THPA). We also analysed 3 SNPs previously associated with survival by anatomical site. …”
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10570
Discovery of novel serum peptide biomarkers for cholangiocarcinoma recurrence through MALDI-TOF MS and LC–MS/MS peptidome analysis
Published 2025-01-01“…LC–MS/MS analysis identified 95 peptides associated with cancer progression in early recurrence and 60 in late recurrence. Distinct protein associations were found: ATR, POLA1, BLM, SP100, and PPP1R15A for early recurrence, and SERPINA1, TGFB2, SERPING1, and CAD for late recurrence, with strong interactions with chemotherapeutic drugs. …”
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10571
Intestinal Permeability Measured by Urinary Sucrose Excretion Correlates with Serum Zonulin and Faecal Calprotectin Concentrations in UC Patients in Remission
Published 2019-01-01“…Likewise, the inflammatory markers C-reactive protein (CRP), calprotectin, and the cytokines IFNγ, TNFα, IL-6, and IL-10 were not significantly affected. …”
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10572
Mir-615-5p inhibits cervical cancer progression by targeting TMIGD2
Published 2025-01-01“…Western blotting was employed to measure the protein levels of TMIGD2. Results In CC, the downregulation of miR-615-5p was related to poor prognosis and emerged as an independent prognostic factor. …”
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10573
Purification of mesenchymal stromal cell‐derived small extracellular vesicles using ultrafiltration
Published 2025-01-01“…Isovolumetric diafiltration was incorporated to enhance the purity of MSC‐sEVs, successfully removing about 99% of protein contaminants by six diafiltration volumes (DVs). …”
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10574
Diagnostic value of interferon-γ release assay in patients with COPD complicated with pulmonary tuberculosis
Published 2025-01-01“…An interferon-γ release assay, a purified protein derivative of tuberculin (PPD) test, an anti-tuberculosis antibody test, a test of Mycobacterium tuberculosis by sputum smear microscopy and a test of Mycobacterium tuberculosis by PCR method were used to test patients in each group. …”
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10575
Deregulated JNK signaling enhances apoptosis during hyperthermia
Published 2024-12-01“…Purpose c-Jun N-terminal kinases (JNKs) comprise a subfamily of mitogen-activated protein kinases (MAPKs). The JNK group is known to be activated by a variety of stimuli. …”
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10576
Selenium-enriched and ordinary green tea extracts prevent high blood pressure and alter gut microbiota composition of hypertensive rats caused by high-salt diet
Published 2022-05-01“…Our results showed that GT and Se-GT supplementations significantly prevented the increase of blood pressure (BP), activated the phosphoinosmde-3-kinase/protein kinase B (PI3K/Akt) signaling pathway, and regulated the gene expression related to BP, as well as improved the tissue damage like heart, liver, and kidneys. …”
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10577
Mechanism of engineered macrophage membrane bionic gene-carrying nanospheres for targeted drug delivery to promote wound repair in deep second-degree burns
Published 2025-01-01“…Immunohistochemistry and Western blotting were performed to determine the expression of relevant proteins. The wound-healing, blood flow and complete epithelialization rates were significantly better in the HGF@ETMM@NPS group compared to the NS and ETMM@NPS groups. …”
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10578
Amyopathic dermatomyositis with a rapidly progressing interstitial pneumonia
Published 2024-11-01“…Background: Clinically amyopathic dermatomyositis (CADM) is a rare subtype of idiopathic inflammatory myositis often linked with the presence of autoantibodies targeting melanoma differentiation-associated protein 5 (MDA5). Patients with CADM are at increased risk of developing rapidly progressing interstitial lung disease, which significantly increases both morbidity and mortality compared to other forms of inflammatory myopathies. …”
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10579
Grain yield, cooking quality, and aroma of fragrant rice as affected by nitrogen source and method of application
Published 2024-11-01“…The combined application of N as a foliar dose and soil application, along with ammonium nitrate and ammonium sulfate, showed improved results for various parameters such as gelatinization temperature, gel consistency, protein content, cooking time, imbibition ratio, 2-AP content, grain aroma, and taste of BRRI dhan70 compared to 100% soil application of N. …”
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10580
The Effects of Garlic and Red Chilli Pepper Powder on Physicochemical, Microbiological, and Sensory Properties of Cincalok
Published 2021-01-01“…Overall, the water, ash, and fat content; titratable acid (TA); total volatile base nitrogen (TVBN); and amino acid nitrogen (AAN) showed insignificant differences (p>0.05) among the recipes during 28 days of the same observation. The crude protein, pH, and free fatty acid (FFA) of recipe C were significantly different (p<0.05) from recipes A and B. …”
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