Validation of a one-step reverse transcription PCR detection method for Tobamovirus maculatessellati, in tomato (Solanum lycopersicum L.) and pepper (Capsicum annuum L.) by Chellappan Padmanabhan, Andrea Gilliard, Kai-Shu Ling, Yazmín Rivera

“…In this study, we report the validation of a previously described reverse transcription polymerase chain reaction (RT-PCR) assay that amplifies a 289 bp fragment of the coat protein coding region of ToMMV genome. This assay has 100% specificity for ToMMV. …”
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Physico-Chemical Characteristics and Sensory Quality of Dry Fermented Sausages with Flaxseed Oil Preparations by Stajić Slaviša, Stanišić Nikola, Lević Steva, Tomović Vladimir, Lilić Slobodan, Vranić Danijela, Jokanović Marija, Živković Dušan

“…The aim of this study was to determine the extent of changes in physico-chemical and sensory properties of dry fermented sausages where pork backfat was partly replaced by flaxseed oil used as liquid (FXL), after encapsulation (FXE), and pre-emulsified with alginate (FXA) and soy protein isolate (FXI). During production and storage, similar pH values of all products were observed. …”
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Interleukin-29 Enhances Synovial Inflammation and Cartilage Degradation in Osteoarthritis by Lingxiao Xu, Qiuyue Peng, Wenhua Xuan, Xiaoke Feng, Xiangqing Kong, Miaojia Zhang, Wenfeng Tan, Meilang Xue, Fang Wang

“…The mRNA levels of IL-29 and its specific receptor IL-28Ra in peripheral blood mononuclear cells (PBMCs) were significantly increased in OA patients when compared to healthy controls (HC). In the serum, IL-29 protein levels were higher in OA patients than those in HC. …”
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RETRACTED: The role of biofield energy treatment on psychological symptoms, mental health disorders, and stress‐related quality of life in adult subjects: A randomized controlled c... by Mahendra Kumar Trivedi, Alice Branton, Dahryn Trivedi, Sambhu Mondal, Snehasis Jana

“…Furthermore, physiological biomarkers: vitamins (B12, C, and D3 metabolites), immune biomarker (CD8+CD28−), neurotransmitters (acetylcholine, noradrenaline, and dopamine), hormones (oxytocin, 17‐β‐estradiol, and insulin), and antiaging protein (klotho) levels were significantly (p ≤ 0.001) increased in treatment group than placebo. …”
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Optimizing Methane Production from Anaerobic Digestion of Dairy Cow Manure: The Potential Use of Carica (Carica pubescens) Seeds as a Co-Substrate by R. Purwasih, M. Saindah, H. Triyuwanti, F. S. Yusuf, A. Purnomoadi, E. Purbowati, S. Sutaryo

“…Treatment P3 contained a substrate containing excessively high protein and organic content, negatively affecting anaerobic microorganisms’ activity. …”
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Liquid chromatography/tandem mass spectrometric characterization of Rhodotorula mucilaginosa GMM natural pigment and its synergistic antitumor effect with γ-radiation: in-vitro and... by Ghada S. Ibrahim, Amal I. Hassan, Manal G. Mahmoud, Mohsen M.S. Asker, Mohamed Marzouk

“…The pigment exhibited DPPH scavenging activity, and the combination of natural pigment and radiation therapy showed a significant reduction (P<0.05) in the levels of matrix metalloproteinases (MMP2, MMP9), and significant increases (P<0.05) in the levels of tumor protein p53, Bax and caspases-3 and caspases-9 in CAOV-3 cell lines and mice bearing solid tumors. …”
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Short-term impact of glycaemic control and intravitreal ranibizumab treatment on serum cytokine levels and diabetic macular edema in patients with unregulated blood glucose by Hürkan Kerimoğlu, İbrahim Kılınc, Bülent Savut, Mustafa Kulaksızoğlu, Günhal Şatırtav, Gülfidan Bitirgen, Emine Tınkır Kayıtmazbatır

“…Methods: Serum cytokine levels, including interleukin (IL)-1β, IL-6, IL-8, tumor necrosis factor-alpha (TNF-α), monocyte chemoattractant protein-1(MCP-1), and vascular endothelial growth factor (VEGF) were analysed at the beginning and at the end of 3 months, using enzyme-linked immunosorbent assays (ELISA). …”
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An Evaluation of the Antibacterial Properties of Tormentic Acid Congener and Extracts From Callistemon viminalis on Selected ESKAPE Pathogens and Effects on Biofilm Formation by Tafadzwa Chipenzi, Genuine Baloyi, Tatenda Mudondo, Simbarashe Sithole, Godloves Fru Chi, Stanley Mukanganyama

“…Tormentic acid congener showed time-dependent antibacterial activity against P. aeruginosa with a MIC of 100 µg/ml and caused significant protein leakage. Antibacterial activity was found when tormentic acid congener was tested against both S. aureus and P. aeruginosa. …”
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Transcriptome analysis of novel B16 melanoma metastatic variants generated by serial intracarotid artery injection by Jenny C. Kienzler, Erick M. Contreras, Janet Treger, Linda M. Liau, Geoffrey C. Owens, Robert M. Prins

“…Gene set enrichment analysis (GSEA) of differentially expressed protein coding genes revealed that cells isolated from the brain as well as from the lung and meninges expressed higher levels of genes associated with an epithelial to mesenchymal transition (EMT), upregulation of the KRAS signaling pathway, and a metastasis aggressiveness gene signature associated with poor survival in melanoma patients. …”
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Plastid-localized ZmENR1/ZmHAD1 complex ensures maize pollen and anther development through regulating lipid and ROS metabolism by Shaowei Zhang, Xueli An, Yilin Jiang, Quancan Hou, Bin Ma, Qingping Jiang, Kai Zhang, Lina Zhao, Xiangyuan Wan

“…Using genetic mapping, we clone a key GMS gene, ZmENR1, which encodes a plastid-localized enoyl-acyl carrier protein (ACP) reductase. ZmENR1 interacts with β-hydroxyacyl-ACP dehydratase (ZmHAD1) to enhance the efficiency of de novo fatty acid biosynthesis. …”
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ISU201 Enhances the Resolution of Airway Inflammation in a Mouse Model of an Acute Exacerbation of Asthma by Yuka Hiroshima, Linda Garthwaite, Kenneth Hsu, Hyouna Yoo, Sang-Ho Park, Carolyn L. Geczy, Rakesh K. Kumar, Cristan Herbert

“…Using a murine model of an acute exacerbation of asthma, we assessed the ability of ISU201, a novel protein drug, to suppress the inflammatory response when administered after induction of an exacerbation. …”
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Clinical Characteristics and Outcome of Kidney Transplant Recipients Infected with COVID-19: A Retrospective Observational Study by Manzoor Ahmad Parry, Rayees Yousuf Sheikh, Raja Kaamil Qadri, Muzafar Maqsood Wani, Imtiyaz Wani, Mohammad Ashraf Bhat

“…The median C-reactive protein (CRP) levels (mg/L) were 19.5 (1QR: 5.0–156.3), 53.9 (1QR: 31.5–96.0), and 63.4 (1QR: 23.2–228) for mild, moderate, and severe cases, respectively (P = 0.006). …”
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Spinal cord injury induces transient activation of hepatic stellate cells in rat liver by Inmaculada Fernandez-Canadas, Alejandro Badajoz, Jesús Jimenez-Gonzalez, Martin Wirenfeldt, Beatriz Paniagua-Torija, Clara Bravo-Jimenez, Mar Del Cerro, Angel Arevalo-Martin, Daniel Garcia-Ovejero

“…We found a transient activation of HSCs after SCI, beginning with the acute downregulation of Glial Fibrillar Acidic Protein 1dpi. This is followed by a morphological and phenotypical transformation into alpha-smooth muscle actin (ACTA2/SMA) immunoreactive myofibroblast-like cells, peaking at 14 days post-injury and returning to control-like levels at later timepoints (45 days post-injury). …”
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Preoperative Nutritional Therapy Reduces the Risk of Anastomotic Leakage in Patients with Crohn’s Disease Requiring Resections by Zhen Guo, Dong Guo, Jianfeng Gong, Weiming Zhu, Lugen Zuo, Jing Sun, Ning Li, Jieshou Li

“…Patients in nutritional therapy (NT) group had a significantly lower level of C-reactive protein on the day before surgery. Patients in NT group suffered less anastomotic leakage (2.3% versus 17.9%, P=0.023) and less temporary diverting stoma (22.8% versus 40.9%, P=0.036). …”
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Efficacy and safety of telitacicept in IgA nephropathy: a real-world study by Lingqiu Dong, Dandan Yang, Aiya Qin, Siqing Wang, Yi Tang, Jiaxing Tan, Wei Qin

“…Telitacicept is a humanized fusion protein composed of a transmembrane activator and calcium-modulating cyclophilin ligand interactor receptor and human IgG.Aim To evaluate the efficacy and safety of telitacicept in adult patients with IgAN in a real-world study.Methods Biopsy-proven IgAN patients with 24-hour proteinuria greater than 0.5 g/d who received 240 mg telitacicept weekly were recruited for this study and 1:1:1 matched with patients who received supportive treatment only or immunosuppressive treatment by propensity score matching. …”
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Paracetamol metabolism by endothelial cells – Potential mechanism underlying intravenous paracetamol-induced hypotension by Johs Dannesboe, Joakim A. Bastrup, Kathrine Holm Nielsen, Pelle Munck, Morten B. Thomsen, Clare L. Hawkins, Thomas A. Jepps

“…Exposure of human coronary artery endothelial cells (HCAECs) to APAP resulted in the formation of protein-bound APAP adducts. Proteomic analysis of HCAECs exposed to APAP showed upregulation of CYP20A1, together with proteins involved in the pentose phosphate pathway and maintaining redox homeostasis. …”
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Effects of Super Nutritional Hepatic Copper Accumulation on Hepatocyte Health and Oxidative Stress in Dairy Cows by Jaimie M. Strickland, Doug Lyman, Lorraine M. Sordillo, Thomas H. Herdt, John P. Buchweitz

“…Tissue-level oxidative stress was assessed by immunohistochemistry using 4-hydroxynonenal (4HNE) and 3-nitrotyrosine (3NIT) stains to score the relative abundance and distribution of oxidized lipid and protein products, respectively. Mean hepatic copper concentration was 496.83 μg/g and median 469.72 μg/g and ranged from 70.56 to 1264.27 μg/g dry tissue. …”
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Proximate Composition, Amino Acid Profile, and Mineral Content of Four Sheep Meats Reared Extensively in Morocco: A Comparative Study by Kamal Belhaj, Farid Mansouri, Abdessamad Ben moumen, Marianne Sindic, Marie-Laure Fauconnier, Mohamed Boukharta, Hana Serghini Caid, Ahmed Elamrani

“…From a nutritional point of view, the studied meats had a good protein and mineral quality, due to their richness in essential amino acids and microelements. …”
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Distinct Redox Signalling following Macrophage Activation Influences Profibrotic Activity by Caitlin V. Lewis, Antony Vinh, Henry Diep, Chrishan S. Samuel, Grant R. Drummond, Barbara K. Kemp-Harper

“…Coculture with human aortic adventitial fibroblasts revealed that M(IL-4), but not M(IFN-γ+LPS), enhanced fibroblast collagen 1 protein expression. Macrophage pretreatment with the hydrogen peroxide scavenger, PEG-catalase, attenuated this effect. …”
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Metabolomics profiles revealed potential biomarkers of Pacific white shrimp (Litopenaeus vannamei) under cold and low salinity stress by Zhenzhu Sun, Pei Lin, Haobin Mai, Leling Chen, Zonglu Wei, Beiping Tan, Chaoxia Ye

“…LC-MS analysis revealed overlapping significant pathways, including ABC transporters, protein digestion, aminoacyl-tRNA biosynthesis, purine metabolism, and pyrimidine metabolism, with an additional pathway (mineral absorption) in the salinity change group. …”
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