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10461
SLC7A5 is required for cancer cell growth under arginine-limited conditions
Published 2025-01-01“…Our screen identified the SLC-family transporter SLC7A5 as required for growth, and we hypothesized that this protein functions as a high-affinity citrulline transporter. …”
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10462
Potential role of aquaculture fish to the recommended nutritional intake (RNI) of children, adults, pregnant and lactating women in Asuogyaman Municipality, Ghana
Published 2025-03-01“…The study used standard methods to analyse the micronutrient and proximate composition of twenty-four samples of three fish species—Heterotitis niloticus, Clarias gariepinus, and Oreochromis niloticus. The protein compositions of Oreochromis niloticus, Clarias gariepinus, and Heterotis niloticus were 17.96 g/100 g, 14.00 g/100 g, and 13.25 g/100 g, respectively. …”
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10463
ATRX loss inhibits DDR to strengthen radio-sensitization in p53-deficent HCT116 cells
Published 2025-01-01“…Alpha-thalassemia/mental retardation X-linked (ATRX), a member of the SWI/SNF-like chromatin remodeling protein family, functions in the maintenance of genomic integrity and the regulation of apoptosis and senescence. …”
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10464
Optimizing the gelation, structure, and thermal stability of alkali-induced duck egg white gels with calcium chloride
Published 2025-01-01“…Alkali treatment is a proven method for producing transparent elastic protein gels and could provide a practical way to utilize surplus duck egg whites that are generated during processing. …”
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10465
Enhanced hemocompatibility, antimicrobial and anti-inflammatory properties of biomolecules stabilized AgNPs with cytotoxic effects on cancer cells
Published 2025-01-01“…Also, the blood-clotting, hemolytic, antioxidant, bactericidal and, fungicidal properties, cytotoxicity effects and inhibition of protein denaturation efficiency of IY-AgNPs were assessed in vitro. …”
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10466
Alpha Lipoic Acid Modulated High Glucose-Induced Rat Mesangial Cell Dysfunction via mTOR/p70S6K/4E-BP1 Pathway
Published 2014-01-01“…These results suggest that LA dose-dependently regulates mesangial cell proliferation and matrix protein secretion by mTOR/p70S6K/4E-BP1 signaling pathway under high glucose conditions.…”
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10467
Relevance of Plasma Obestatin and Early Arteriosclerosis in Patients with Type 2 Diabetes Mellitus
Published 2013-01-01“…We found that higher levels of fasting insulin (Fins), fasting blood glucose, 2 h OGTT glucose, homeostasis model assessment of insulin resistance (HOMA-IR), low density lipoprotein cholesterol, glycated haemoglobin, and C-reactive protein (CRP), as well as lower obestatin level and higher intima-media thickness level (IMT), existed in T2DM group compared with NGT group and IGT group (P<0.01). …”
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10468
Procalcitonin and High APACHE (Acute Physiological and Chronic Health Evaluation) Level Are Associated with the Course of Acute Kidney Injury in Patients with SARS-CoV-2
Published 2022-01-01“…We investigated the association between inflammatory markers (C-reactive protein, procalcitonin, D-dimer, lactate dehydrogenase, and ferritin) in patients infected with SARS-CoV-2 and the development of AKI. …”
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10469
Differential detoxification enzyme profiles in C-corn strain and R-rice strain of Spodoptera frugiperda by comparative genomic analysis: insights into host adaptation
Published 2025-01-01“…Functional predictions and protein interaction networks suggest a broader expansion of metabolism-related genes in the R strain compared to the C strain. …”
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10470
Evaluation of Sericin/Polyvinyl Alcohol Mixtures for Developing Porous and Stable Structures
Published 2025-01-01“…These cocoons primarily contain fibroin and sericin (SS) proteins along with minor amounts of wax and mineral salts. …”
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10471
Leptin Enhances Synthesis of Proinflammatory Mediators in Human Osteoarthritic Cartilage—Mediator Role of NO in Leptin-Induced PGE2, IL-6, and IL-8 Production
Published 2009-01-01“…The results suggest that the effects of leptin are mediated through activation of transcription factor nuclear factor κB (NF-κB) and mitogen-activated protein kinase (MAPK) pathway c-Jun NH2-terminal kinase (JNK). …”
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10472
Connexin 37 Regulates the Kv1.3 Pathway and Promotes the Development of Atherosclerosis
Published 2022-01-01“…The indexes of body weight, blood glucose, and blood lipid of mice were collected. The protein and mRNA expression levels of Cx37 and Kv1.3 were detected by reverse transcription-PCR (RT-PCR), Western blot, and immunofluorescence technique. …”
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10473
Citrullinated Antigens with Multiple Citrulline Similar Motif in the Diagnosis of Rheumatoid Arthritis: A Preliminary Single-Center Study
Published 2021-01-01“…The presence of anti-citrullinated protein antibodies (ACPAs) in the serum is one of the immunological features of rheumatoid arthritis (RA). …”
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10474
Indoleamine 2,3-Dioxygenase (IDO) Expression Is an Independent Prognostic Marker in Esophageal Adenocarcinoma
Published 2020-01-01“…We analyzed 551 patients with EAC using single-protein and multiplex immunohistochemistry as well as mRNA in situ technology for the expression and distribution of IDO on subtypes of TILs (INF-γ mRNA and CD4- and CD8-positive T lymphocytes). …”
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10475
Sulforaphane enhances Nrf2-mediated antioxidant responses of skeletal muscle induced by exhaustive exercise in HIIT mice
Published 2022-09-01“…Importantly, SFN treatment improved antioxidative capacity of skeletal muscle in response to the acute exhaustive exercise by increasing mRNA and nucleoprotein expression of Nrf2 and these genes involved in antioxidant generation and decreasing blood creatine kinase (CK) and 4-hydroxy-2-nonenal (4-HNE)-modified protein levels in the HIIT mice.…”
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10476
Hepatoprotective Effects of Nasturtium Officinale and Allium Polyanthum Extracts on CCL4- Induced Hepatic Damage In Albino Rats
Published 2022-01-01“…Aspartate aminotransferase (AST), Alanine aminotransferase (ALT), Alkaline phosphatase (ALP), Total serum bilirubin (TSB), Total protein (TP), Albumin (ALB) and malondialdehyde (MDA) were measured in serum at the end of the study. …”
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10477
Morphological Characters, Yield, and Chemical Composition Potentials of Desho Grass (Pennisetum glaucifolium H.) Intercropped with Vetch Species in the Highlands of Ethiopia
Published 2022-01-01“…Intercropping of vetch species/varieties with desho grass had shown significantly (P<0.001) higher dry matter yield than sole desho except desho with V. sativa. The highest crude protein (CP) content was obtained from desho grass intercropped with two V. villosa (Var-Lalisa and Var-Gebisa) at 90 days of harvesting age. …”
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10478
Heat stress on the feed consumption, biochemical indicators, production and milk quality of holstein and jersey cows
Published 2025-01-01“…For dry matter intake, there was a treatment*day interaction, and the milk yield and composition of the treatments were similar. Only the protein content was greater in the VA treatment group than in the SVA group. …”
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10479
Proteomic profiling identifies muscle-invasive bladder cancers with distinct biology and responses to platinum-based chemotherapy
Published 2025-02-01“…Post-neoadjuvant chemotherapy clusters appear to be differentially enriched for druggable proteins. For example, MTOR and PARP are over-expressed at the protein level in tumours identified as neuronal-like. …”
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10480
Survivin is Highly Expressed and Promotes Cell Survival in Malignant Peritoneal Mesothelioma
Published 2007-01-01“…In the present study, we assessed the expression of survivin and other members of the inhibitors of apoptosis proteins (IAP) family (IAP-1, IAP-2 and X-IAP) in a series of 32 MPM surgical specimens and investigated the effects of survivin knockdown in an established MPM cell line. …”
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