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10201
Cell-membrane targeting sonodynamic therapy combination with FSP1 inhibition for ferroptosis-boosted immunotherapy
Published 2025-02-01“…However, ferroptosis is restrained by the ferroptosis suppressor protein 1 (FSP1) at the plasma membrane, which can catalyze the regeneration of ubiquinone (CoQ10) by using NAD(P)H to suppress the LPO accumulation. …”
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10202
An efficiently biological nitrogen fixation of non-native Lotus tenuis justifies its key role in the flooding Pampas (Argentina)
Published 2025-01-01“…The results showed that L. tenuis promotion was accompanied by an increase in forage quality improving the Crude Protein (CP) content and the Digestibility of Dry Matter (DDM). …”
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10203
Evaluation of Cinnamon Essential Oil and Its Emulsion on Biofilm-Associated Components of <i>Acinetobacter baumannii</i> Clinical Strains
Published 2025-01-01“…The effect was monitored not only with regard to the whole biofilm biomass, but also on the individual components of the biofilm matrix such as exopolysaccharides, proteins, and eDNA molecules. Protein share drops in treated biofilms demonstrated the most consistency among strains and rose to 75%. …”
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10204
Muscarinic Receptors Types 1 and 2 in the Preoptic-Anterior Hypothalamic Areas Regulate Ovulation Unequally in the Rat Oestrous Cycle
Published 2017-01-01“…The number of m2AChR-immunoreactive cells was significantly higher at 09:00 h on each day of the oestrous cycle in the POA-AHA region, while no changes in the expression profile of m1AChR protein were observed. The ovulation rate in rats treated with PZP on the oestrous day was lower than that in the vehicle group. …”
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10205
Finding potential inhibitors from phytochemicals against nucleoprotein of crimean congo fever virus using in silico approach
Published 2024-12-01“…Former studies on CCHF have reported that the nucleoprotein of CCHF, being a pivotal protein in the replication process of the virus, is a potential target for antiviral drugs. …”
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10206
Novel equations for estimating gross energy in feed ingredients for non-ruminants
Published 2025-01-01“…Methods A total of 2,279 ingredient samples consisted of barley (n = 58), corn (n = 319), corn distillers dried grains with solubles (n = 13), corn gluten feed (n = 583), copra expellers (n = 156), copra meal (n = 234), cottonseed meal (n = 12), palm kernel expellers (n = 504), rapeseed meal (n = 114), soybean meal (n = 138), wheat (n = 70), and wheat bran (n = 78) were analyzed for dry matter (DM), crude protein (CP), ether extract (EE), crude fiber, ash, and GE. …”
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10207
Evolution of Functional and Paraclinical Markers as Predictive Factors in Pediatric Late-Onset SMA Under Nusinersen Treatment: The Role of CSF pNF-H
Published 2025-12-01“…Spinal Muscular Atrophy (SMA) is a rare neurodegenerative disease caused by insufficient synthesis of SMN protein, characterized by progressive muscle weakness, atrophy, and complications affecting the respiratory and digestive systems. …”
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10208
RETRACTED: The role and molecular mechanism of Trop2 induced epithelial‐mesenchymal transition through mediated β‐catenin in gastric cancer
Published 2019-03-01“…Meanwhile, the elevated protein levels of Trop2 and mesenchymal markers were also found in the TGF‐β1‐induced EMT model in GC cells. …”
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10209
Telomere Length in Neonatal Dairy Calves in Relation to Lifetime Parameters
Published 2025-01-01“…However, categorical analyses revealed that calves with the longest TL had lower lifetime fat (<i>p</i> = 0.01) and protein yields (<i>p</i> = 0.01) than those with the shortest TL. …”
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10210
Non‐Invasive Tumor‐Naïve Minimal Residual Disease Detection of Liver Cancer by Incorporating Circulating Tumor DNA Features and Alpha‐Fetoprotein: A Prospective Study
Published 2024-12-01“…This process integrated protein tumor marker alpha‐fetoprotein (AFP) and cancer genomic hallmarks, copy number aberration (CNA) and fragment size (FS). …”
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10211
Study on Management of Blood Transfusion Therapy in Patients with Hereditary Spherocytosis
Published 2022-01-01“…Based on the sequencing results, the type of mutated membrane protein in each proband was analyzed using the eosin-5′-maleimide (EMA) binding test and sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE). …”
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10212
Complete Mitochondrial Genome of <i>Niphon spinosus</i> (Perciformes: Niphonidae): Genome Characterization and Phylogenetic Analysis
Published 2025-01-01“…The typical set of 13 protein-coding genes (PCGs), 2 rRNA genes, 22 tRNA genes, and one control region (D-loop) are included in the mitochondrial genome. …”
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10213
Ezetimibe Anticancer Activity via the p53/Mdm2 Pathway
Published 2025-01-01“…Background: Ezetimibe is used to treat cardiovascular disease as it blocks the sterol transporter Niemann-Pick C1-Like 1 (NPC1CL1) protein. However, recent evidence indicates that Ezetimibe inhibits several cancers indirectly by reducing circulating cholesterol or via specific signalling pathways. …”
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10214
Could serum Raftlin and GPER-1levels be new biomarkers for early detection of non-small cell lung cancer?
Published 2025-01-01“…In this study, we investigated blood levels of G-protein associated membrane estrogen receptor (GPER)-1 and Raftlin as markers of early-stage in lung cancer. …”
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10215
Recovery from Liver Failure and Fibrosis in a Rat Portacaval Anastomosis Model after Neurointermediate Pituitary Lobectomy
Published 2021-01-01“…In comparison with those in the IC and PCA groups, bilirubin, protein serum, and liver glycogen levels were restored in the PCA+NIL group. …”
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10216
Ferroptosis triggers mitochondrial fragmentation via Drp1 activation
Published 2025-01-01“…The large GTPase Dynamin-related protein 1 (Drp1) is intimately involved in mediating constitutive mitochondrial fission and has been implicated in mitochondrial cell death pathways. …”
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10217
Selection of specific nanobodies against peanut allergen through unbiased immunization strategy and the developed immuno-assay
Published 2023-05-01“…In this study, nanobodies (Nbs) derived from the Heavy-Chain only Antibodies (HCAbs) were selected against the general peanut protein extract through the unbiased strategy to facilitate the development of the sandwich ELISA for the detection and surveillance of peanut allergen contamination. …”
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10218
Downregulation of RIPK4 Expression Inhibits Epithelial-Mesenchymal Transition in Ovarian Cancer through IL-6
Published 2021-01-01“…At the molecular level, silencing RIPK4 significantly downregulated vimentin, N-cadherin, and Twist expression but induced an increase in the protein level of E-cadherin and inhibited the IL-6 and STAT3 levels. …”
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10219
Downregulation of Bcl-2 Expression by miR-34a Mediates Palmitate-Induced Min6 Cells Apoptosis
Published 2014-01-01“…Intriguingly, ectopic expression of miR-34a lowered the expression of Bcl-2, an antiapoptotic protein. Luciferase reporter assay indicated the direct interaction of miR-34a with the Bcl-2 3′-UTR. …”
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10220
Sox9-Increased miR-322-5p Facilitates BMP2-Induced Chondrogenic Differentiation by Targeting Smad7 in Mesenchymal Stem Cells
Published 2021-01-01“…Bone morphogenetic protein 2 (BMP2) induces effective chondrogenesis of mesenchymal stem cells (MSCs) by promoting Sox9 expression. …”
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