Royal Jelly and Its Dual Role in TNBS Colitis in Mice by Luis Paulo Manzo, Felipe Meira de-Faria, Ricardo José Dunder, Eduardo Augusto Rabelo-Socca, Silvio Roberto Consonni, Ana Cristina Alves de Almeida, Alba Regina Monteiro Souza-Brito, Anderson Luiz-Ferreira

“…Intestine samples of the animals orally treated with RJ (100, 150, and 200 mg/kg) were collected for antioxidant assays (GSH and GSH-Px), proinflammatory protein quantification (COX-2 and NF-κB), and histological analyses. …”
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Novel primers drive accurate SYBR Green PCR detection of Listeria monocytogenes and Listeria innocua in cultures and mushrooms by Bo-eun Kim, Ravi Jothi, Da woon Kim, Dong Suk Park

“…By performing a comparative analysis of the complete genome sequences of L. monocytogenes (ATCC 12392) and L. innocua (CFSAN044836), a unique gene region encoding a hypothetical protein with an LPXTG cell wall anchor domain (GCF_003031895.1) in L. monocytogenes and leucine-rich repeats (GCF_009648575.1) in L. innocua was identified. …”
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Enhanced extracellular production of alpha-lactalbumin from Bacillus subtilis through signal peptide and promoter screening by Yuqi Zhu, Pengdong Sun, Chunjian Li, Yu Zhang, Yu Wang, Jingyuan Li, Yanfeng Liu, Jian Chen, Yang Deng

“…Alpha-lactalbumin (α-LA) is a major whey protein found in breast milk and plays a crucial role in the growth and development of infants. …”
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Potential Pathways Involved in Elaidic Acid Induced Atherosclerosis in Human Umbilical Vein Endothelial Cells by Huahong Yu, Xiangmei Li, Zhongshang Liang, Bin Qiu, Siguang Li, Ting Luo, Jing Li, Hongyan Li, Zeyuan Deng

“…The expressions of some selected proteins (PSME3, XRCC5, GSTP1, and GSTO1) were validated by qRT-PCR analysis. …”
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Proline Promotes Drought Tolerance in Maize by Pirzada Khan, Ashraf M. M. Abdelbacki, Mohammed Albaqami, Rahmatullah Jan, Kyung-Min Kim

“…Proline also increased the protein content and improved N, P, and K retention by 30%, 40%, and 28%, respectively, in the drought-stressed plants, supporting metabolic and osmotic balance. …”
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Association of Biomarker Level with Cardiovascular Events: Results of a 4-Year Follow-Up Study by L. Turgunova, B. Baidildina, Y. Laryushina, B. Koichubekov, A. Turmukhambetova, L. Akhmaltdinova

“…The study aimed to investigate the predictive value of chemokine (C-X-C motif) ligand 16 (CXCL16), endocan, and heart-type fatty acid binding protein (H-FABP) in the cardiovascular event development in people who are not known to have cardiovascular events in their history. …”
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Sex-Based Variations in Hemato-Physiological Characteristics of Patients with Major Depressive Disorder: Clinical and Socioeconomic Insights by Basim A. Abd, Hayder Abdul-Amir Makki Al-Hindy, Samer Raheem Obaid

“…Materials and Methods: The study collected basic demographic characteristics, including age, leukocyte counts, body mass index (BMI), hemoglobin (Hb) blood values, and inflammatory marker “C-reactive protein” (CRP). The cohort exhibited significant alterations between the two sexes in various clinical variables. …”
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Helicobacter Pylori infection in systemic sclerosis and its association with upper gastrointestinal dysfunction by Chilukuri Balaji, Mahendran Bhuvanesh, Chinnadurai Saranya, Ramamoorthy Ramesh, Mayilsamy Saravanan, Sankaralingam Rajeswari

“…Anti-H. pylori IgG antibody levels showed no correlation with disease duration, erythrocyte sedimentation rate, C-reactive protein, interstitial lung disease, and modified Rodnan Skin Score. …”
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Upregulation of TCPTP in Macrophages Is Involved in IL-35 Mediated Attenuation of Experimental Colitis by Baoren Zhang, Chenglu Sun, Yanglin Zhu, Hong Qin, Dejun Kong, Jingyi Zhang, Bo Shao, Xiang Li, Shaohua Ren, Hongda Wang, Jingpeng Hao, Hao Wang

“…Therefore, we constructed Pichia pastoris stably expressing IL-35 which enables the cytokines to reach the diseased mucosa, and explored whether upregulation of T-cell protein tyrosine phosphatase (TCPTP) in macrophages is involved in the mechanisms of IL-35-mediated attenuation of UC. …”
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Proline and ROS: A Unified Mechanism in Plant Development and Stress Response? by Marco Renzetti, Dietmar Funck, Maurizio Trovato

“…The proteinogenic amino acid proline plays crucial roles in both plant development and stress responses, far exceeding its role in protein synthesis. However, the molecular mechanisms and the relative importance of these additional functions of proline remain under study. …”
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Hepatotoxic Effects of Gaseous Sulfur Dioxide (SO₂), Nitrogen Dioxide (NO₂), and Their Mixture on Sea Bass (Centropristis striata): Hematological, Biochemical and Genotoxic Studies... by N. Gandhi, Y. Rama Govinda Reddy and Ch. Vijaya

“…Treatment groups, subjected to LC30, LC50, and LC90 acute exposure of gaseous SO2, NO2, and SO2+NO2, alongside a control group, underwent evaluation of parameters such as red and white blood cells, hemoglobin, hematocrit, mean corpuscular hemoglobin, mean corpuscular volume, mean corpuscular hemoglobin concentration, alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, acid phosphatase, lactate dehydrogenase, total protein, albumin, serum creatinine, and blood urea. …”
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First Trimester Aneuploidy Screening Program for Preeclampsia Prediction in a Portuguese Obstetric Population by Cláudia Teixeira, Eduardo Tejera, Helena Martins, António Tomé Pereira, Altamiro Costa-Pereira, Irene Rebelo

“…Logistic regression-based predictive models were developed for prediction of PE based on maternal characteristics, crown-rump length (CRL), nuchal translucency thickness (NT), and maternal serum levels of pregnancy-associated plasma protein-A (PAPP-A) and free beta-subunit of human chorionic gonadotropin (free β-hCG). …”
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Astragaloside IV inhibits pathological functions of gastric cancer-associated fibroblasts through regulation of the HOXA6/ZBTB12 axis by Liu Haibo, Luo Shicheng, Sha Xiaofeng, Chen Zhiping, Yang Dongdong

“…HOXA6 silencing also induced the downregulation of ZBTB12 mRNA and protein in CAFs. Astragaloside IV was demonstrated to regulate the expression of ZBTB12 by mediating the transcriptional activity of HOXA6. …”
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Progress on mitochondria and hair follicle development in androgenetic alopecia: relationships and therapeutic perspectives by Ting-ru Dong, Yu-jie Li, Shi-yu Jin, Feng-lan Yang, Ren-xue Xiong, Ye-qin Dai, Xiu-zu Song, Cui-ping Guan

“…We discuss the cellular and signaling mechanisms associated with hair loss and examine how mitochondrial dysfunction, such as insufficient energy supply, signaling irregularities, protein/gene abnormalities, and programmed cell death, can hinder the normal proliferation, differentiation, and growth of hair follicle cells. …”
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Neurological Disease-Affected Patients, including Multiple Sclerosis, Are Poor Responders to BKPyV, a Human Polyomavirus by Ilaria Bononi, Elisa Mazzoni, Silvia Pietrobon, Maria Rosa Iaquinta, Andrea Caselli, Elena Torreggiani, Maura Pugliatti, Ilaria Casetta, Massimiliano Castellazzi, Enrico Granieri, Fernanda Martini, Mauro Tognon

“…Samples were analyzed for IgG antibodies against BKPyV with an indirect ELISA with synthetic peptides mimicking the viral capsid protein 1 (VP1) antigens. As control, ELISAs were carried out to verify the immune response against the Epstein-Barr virus (EBV) of patients and controls. …”
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Effects of Different Cultivation Modes on the Storage Quality and Flavor of Harvested Chinese Leek by ZHOU Xinyuan, TAO Jiejie, LIU Mingchi, ZUO Jinhua, WU Zhanhui, ZHENG Yanyan, KANG Xinna, LIANG Hao, MU Jianlou, CHEN Jie, JI Yanhai

“…Compared with hydroponics, soil culture and substrate culture better maintained vitamin C (VC) and soluble protein contents, and resulted in higher dietary fiber content. …”
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Erythropoietin Activates Autophagy to Regulate Apoptosis and Angiogenesis of Periodontal Ligament Stem Cells via the Akt/ERK1/2/BAD Signaling Pathway under Inflammatory Microenviro... by Denghao Huang, Jie Lei, Xingrui Li, Zhonghao Jiang, Maoxuan Luo, Yao Xiao

“…Western blot and immunofluorescence were applied to testify the protein expression level. Results. Periodontal ligament stem cells upregulated apoptosis and suppressed autophagy and angiogenesis under inflammatory microenvironment. …”
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Chloroplast genome characteristics and phylogenetic analysis of Macropanax rosthornii (Harms) C.Y. Wu ex G. Hoo (Araliaceae) by Shuxin Du, Huiying Huang, Shuhui Yang, Tianyi Gu, Mengli Zhou, Ruihong Wang

“…There are 109 genes in the chloroplast genome of M. rosthornii, including 78 protein-coding genes, 21 tRNA genes, and 10 rRNA genes. …”
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Changes in Claudin-4 expression and tight junction integrity in human esophageal cancer: A Systematic Review by Mahsa Mahdizadeh, Zahra Arab-Bafrani, Seyyed Mehdi Jafari

“…Claudin-4 (CLDN-4) is one of the tight junction regulatory proteins whose changes are involved in cancer formation. …”
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Interleukin-1β Accelerates the Onset of Stroke in Stroke-Prone Spontaneously Hypertensive Rats by Tsuyoshi Chiba, Tatsuki Itoh, Masaki Tabuchi, Toru Nakazawa, Takao Satou

“…Gene expressions of IL-1β, IL-1 receptors, caspase-1, and downstream genes (MCP-1 and ICAM-1), which associated with immune cell recruitment, were significantly greater in SHRSP than in WKY or SHR, coincident with greater NFκB protein levels in SHRSP compared to WKY or SHR. In addition, continuous administration of IL-1β (2 μg/day) using an osmotic pump slightly increased the incidence of stroke in SHR (P=0.046) and significantly accelerated the onset of stroke in SHRSP (P=0.006) compared to each control (n=10 per group). …”
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