Expression of USP18 and IL2RA Is Increased in Individuals Receiving Latent Tuberculosis Treatment with Isoniazid by Eleane de Oyarzabal, Lourdes García-García, Claudia Rangel-Escareño, Leticia Ferreyra-Reyes, Lorena Orozco, María Teresa Herrera, Claudia Carranza, Eduardo Sada, Esmeralda Juárez, Alfredo Ponce-de-León, José Sifuentes-Osornio, Robert J. Wilkinson, Martha Torres

“…Expression of chemokine ligand 4 (CCL4), chemokine ligand 10 (CXCL10), chemokine ligand 11 (CXCL11), interferon alpha (IFNA), radical S-adenosyl methionine domain-containing 2 (RSAD2), ubiquitin-specific peptidase 18 (USP18), interferon-induced protein 44 (IFI44), interferon-induced protein 44 like (IFI44L), interferon-induced protein tetratricopeptide repeats 1(IFIT1), and interleukin 2 receptor subunit alpha (IL2RA) mRNA levels were assessed by qPCR before, during, and after INH treatment. …”
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LUBAC Formation Is Impaired in the Livers of Mice with MCD-Dependent Nonalcoholic Steatohepatitis by Yasuka Matsunaga, Yusuke Nakatsu, Toshiaki Fukushima, Hirofumi Okubo, Misaki Iwashita, Hideyuki Sakoda, Midori Fujishiro, Takeshi Yamamotoya, Akifumi Kushiyama, Shin-ichiro Takahashi, Yoshihiro Tsuchiya, Hideaki Kamata, Fuminori Tokunaga, Kazuhiro Iwai, Tomoichiro Asano

“…Recently, it was reported that the new ubiquitin ligase complex termed linear ubiquitin chain assembly complex (LUBAC), composed of SHARPIN (SHANK-associated RH domain-interacting protein), HOIL-1L (longer isoform of heme-oxidized iron-regulatory protein 2 ubiquitin ligase-1), and HOIP (HOIL-1L interacting protein), forms linear ubiquitin on NF-κB essential modulator (NEMO) and thereby induces NF-κB pathway activation. …”
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MSC-exosomes pretreated by Danshensu extracts pretreating to target the hsa-miR-27a-5p and STAT3-SHANK2 to enhanced antifibrotic therapy by Jiabin Liang, Jingxiu Zhao, Lin Yang, Qian Wang, Jing Liao, Jianhao Li, Weizhao Zhuang, Fanghong Li, Jinxian He, Yukuan Tang, Hanwei Chen, Chen Huang

“…Methods The in vitro studies included the effects of DSS duration on MSCs, and the characterization of DSS-Exo and Exo, followed by the assessment of RNA and protein expression levels of peritoneal fibrosis markers and inflammatory cytokines levels after treating human peritoneal mesothelial (HMrSV5) cells. …”
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Absence of MCJ/DnaJC15 promotes brown adipose tissue thermogenesis by Beatriz Cicuéndez, Alfonso Mora, Juan Antonio López, Andrea Curtabbi, Javier Pérez-García, Begoña Porteiro, Daniel Jimenez-Blasco, Pedro Latorre-Muro, Paula Vo, Madison Jerome, Beatriz Gómez-Santos, Rafael Romero-Becerra, Magdalena Leiva, Elena Rodríguez, Marta León, Luis Leiva-Vega, Noemi Gómez-Lado, Jorge L. Torres, Lourdes Hernández-Cosido, Pablo Aguiar, Miguel Marcos, Martin Jastroch, Andreas Daiber, Patricia Aspichueta, Juan Pedro Bolaños, Jessica B. Spinelli, Pere Puigserver, José Antonio Enriquez, Jesús Vázquez, Cintia Folgueira, Guadalupe Sabio

“…This study describes the role of the mitochondrial protein Methylation-controlled J protein (MCJ/DnaJC15) in orchestrating brown adipose tissue (BAT) thermogenesis. …”
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Ibuprofen reduces inflammation, necroptosis and protects photoreceptors from light-induced retinal degeneration by Ping-Wu Zhang, Zi-He Wan, Weifeng Li, Abhishek Vats, Kunal Mehta, Laura Fan, Lingli Zhou, Sean Li, Gloria Li, Casey J. Keuthan, Cynthia Berlinicke, Cheng Qian, Noriko Esumi, Elia J Duh, Donald J. Zack

“…The cellular location and protein expression of key necroptosis genes were assessed by immunohistochemistry. …”
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Study of senile astheny markers against the background of acute inflammatory process in elderly and senile patients in emergency abdominal surgery by M. B. Danyliuk, S. M. Zavhorodnii, Ye. R. Fedotov, Ye. K. Mykhalchenko, I. V. Dobrodub

“…Based on the literature analysis, we selected markers of malnutrition syndrome: total protein, albumin and cholesterol levels, and the marker of sarcopenia – somatotropic hormone. …”
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Natural Product Identification and Molecular Docking Studies of Leishmania Major Pteridine Reductase Inhibitors by Moses N. Arthur, George Hanson, Emmanuel Broni, Patrick O. Sakyi, Henrietta Mensah-Brown, Whelton A. Miller, Samuel K. Kwofie

“…A 100 ns MD combined with molecular mechanics Poisson–Boltzmann surface area (MM/PBSA) calculations confirmed the robust binding interactions and provided insights into the dynamics and stability of the protein–ligand complexes.…”
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Network and systems biology approaches help investigate gene regulatory interactions between Salmonella disease and host in chickens: Model‐based in silico evidence combined with g... by Reza Tohidi, Hoda Javaheri Bargourooshi, Arash Javanmard

“…These include inducible nitric oxide synthase, NRAMP1, immunoglobulin light chain (IgL), transforming growth factor B family (TGFb2, TGFb3 and TGFb4), interleukin 2 (IL2), apoptosis inhibitor protein 1 (IAP1), TLR4, myeloid differentiation protein 2 (MD2), IFNγ, caspase 1 (CASP1), lipopolysaccharide‐induced tumour necrosis factor (LITAF), cluster of differentiation 28 (CD28) and prosaposin (PSAP). …”
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Renewal of wheat cultivars enhances ozone resistance in yield but detrimentally impacts quality: a survey of Chinese wheat by Yinsen Qian, Zheng Zhao, Yifan Cao, Quan Ma, Nanyan Zhu, Lingqi Song, Min Zhu, Min Zhu, Chunyan Li, Chunyan Li, Jinfeng Ding, Jinfeng Ding, Wenshan Guo, Wenshan Guo, Xinkai Zhu, Xinkai Zhu, Xinkai Zhu

“…Our findings also revealed that elevated O3 concentration led to higher sedimentation values and protein content while lowering bulk density, hardness, and starch content. …”
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Bisphenol A attenuates testosterone synthesis via increasing apolipoprotein A1-mediated reverse cholesterol transport in mice by Tong Zhao, Tong Zhao, Wenzhe Yang, Wenzhe Yang, Feilong Pan, Feilong Pan, Jinhao Wang, Jinhao Wang, Wenqi Shao, Wenqi Shao, Fangfang Chen, Fangfang Chen, Kexiang Liu, Kexiang Liu, Shuchen Zhao, Shuchen Zhao, Lijia Zhao, Lijia Zhao

“…Testes were collected for protein extraction, RNA extraction, Oil red O staining or for Biochemical analysis. …”
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Approaches to modulate buffalo gut microbiome for efficient feed utilization and reduced environmental pollution by Vijit Dey, Puran C. Lailer, Tirtha K. Datta

“…Hyper ammonia- producing bacteria (HAB) are responsible for a faster rate of ammonia production from dietary protein degradation, resulting in wastage of feed protein and environmental pollution. 16S rRNA sequences of enrichment culture of buffalo rumen content revealed Proteo-bacteria (61.1 - 68.2%) as most predominant bacteria followed by Unclassified bacteria (24-29%), Firmicutes (2.8-6.9%), Bacteriodetes (0.9-2%), Actinobacteria (0.1-1.1%), Fusobacteria (0.04-0.7%) and Synergistetes (0.1-0.4%) at phylum level. …”
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Dietary Cinnamaldehyde Enhances Growth Performance, Digestion, Immunity, and Lipid Metabolism in Juvenile Fat Greenling (Hexagrammos otakii) by Yixin Gu, Jian Han, Wenjie Wang, Yu Zhan, Huijie Wang, Wenyuan Hua, Yue Liu, Yafeng Guo, Zhuang Xue, Wei Wang

“…Fish-fed diets containing 400 mg/kg and 600 mg/kg CNE had a higher level of crude protein in muscles than the control diet (P<0.05). …”
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Tumor CEMIP drives immune evasion of colorectal cancer via MHC-I internalization and degradation by Ying Zhu, Jiao Li, Tao Zhang, Lei Zhao, Min Jin, Jinghua Ren, Jing Tang, Haihong Wang, Zhenyu Lin, Qing Liang, Ruiqi Li, Biying Zhang, Qingling Hua, Guojie Xu, Jiayuan Chen, Lanqing Wang, Dejun Zhang, Dandan Yu

“…Flow cytometry analysis was used to examine immune cells. Protein–protein interactions were investigated by co-immunoprecipitation and proximity ligation assays. …”
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Phytochemical Analysis, Antioxidant Activity, Antimicrobial Activity, and Cytotoxicity of Chaptalia nutans Leaves by Letiele Bruck de Souza, Amanda Leitão Gindri, Thainara de Andrade Fortes, Thais Felli Kubiça, Jefferson Enderle, Rafael Roehrs, Sidnei Moura e Silva, Vanusa Manfredini, Elton Luís Gasparotto Denardin

“…Antibacterial results revealed only a positive result (antimicrobial activity) for the hexane fraction which significantly inhibited the microorganisms E. epidermidis, C. tropicalis, C. glabrata, and C. krusei at a concentration of 1000 μg/mL. TBARS, carbonyl protein, and DCFH demonstrate that the extract has the ability to protect the cell from protein and lipid damage, as well as the inhibition of oxygen-derived radicals at the three concentrations tested: 0.1, 1, and 10 mg/mL. …”
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Altered AKT1 and MAPK1 Gene Expression on Peripheral Blood Mononuclear Cells and Correlation with T-Helper-Transcription Factors in Systemic Lupus Erythematosus Patients by Sonia Garcia-Rodriguez, Jose-Luis Callejas-Rubio, Norberto Ortego-Centeno, Esther Zumaquero, Raquel Ríos-Fernandez, Salvador Arias-Santiago, Pilar Navarro, Jaime Sancho, Mercedes Zubiaur

“…Plasma IL-1β, IL-6, IL-2, IFN-γ, TNF-α, IL-10, and IL-13 correlated with C-reactive protein, respectively. Increased Calprotectin correlated with neutrophils. …”
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Alimentation d’une population historique by Estelle Herrscher

“…Although the samples were small, the data indicate an increase in protein consumption between the 14th and 15th centuries, which may correlate with greater longevity and taller stature; the individuals buried in the cloister may have had access to a diet richer in animal protein than those buried in the church square. …”
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The genome sequence of the Pacific oyster, Magallana gigas (Thunberg, 1793) [version 2; peer review: 2 approved, 1 approved with reservations] by Rebekka Uhl, Rob Mrowicki

“…Gene annotation of this assembly on Ensembl identified 19,775 protein-coding genes.…”
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Pureed Foods: Lentil Desserts by Wendy J Dahl, Alison O'Donoughue

“… A pureed diet may be recommended for individuals with swallowing problems; however, it can be challenging for those with a puréed diet to receive adequate protein, fiber, vitamins, and minerals. This 4-page document provides recipes made with puréed lentils, offering desserts that are both tasty and nutrient-dense. …”
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Growth and Feed Efficiency of Red Tilapia (Oreochromis sp.) Reared in Different Salinities by Mia Setiawati, M. Agus Suprayudi

“…Dietary growth rate, feed efficiency, protein and lipid retention increased with increasing salinity (p…”
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Fish Fillet: White Versus Red, Structure and Nutritional Composition by Rose Omidvar, Michael Sipos, Razieh Farzad

“… Fish is one of the primary sources of protein and other nutrients globally. There are thousands of food fish species with different chemical compositions and nutritional characteristics of fillets. …”
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