Increasing the concentration of plasma molecules improves the biological activity of platelet-rich plasma for tissue regeneration by Mikel Sánchez, Jon Mercader Ruiz, Daniel Marijuán Pinel, Pello Sánchez, Nicolás Fiz, Jorge Guadilla, Juan Azofra, Maider Beitia, Diego Delgado

“…The present work studies the effectiveness of a novel type of PRP named ‘balanced protein-concentrate plasma’ (BPCP). Different growth factor (GF) levels were measured using Enzyme Linked Immunosorbent Assay (ELISA), and in addition to the increase in intra-platelet GFs found in standard PRP (sPRP), BPCP also showed a higher concentration of plasmatic protein. …”
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Molecular investigation on active compounds in papaya leaves (Carica papaya Linn) as anti-malaria using network pharmacology, molecular docking, clustering-based analysis and molec... by Arwansyah Arwansyah, Sitti Rahmawati, Siti Nuryanti, Yenni Yusuf, Hartono, Abdur Rahman Arif

“…Hence, we investigate the active compounds in Carica papaya Linn as potential drugs against malaria using pharmacology combined with several in silico methods. A total of 23 proteins linked to the active compounds and malaria-related targets in human proteins were identified using network analysis. …”
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Functional-proteomics-based investigation of the cellular response to farnesyltransferase inhibition in lung cancer by Yanbo Pan, Olena Berkovska, Soumitra Marathe, Georgios Mermelekas, Greta Gudoityte, Amare D. Wolide, Taner Arslan, Brinton Seashore-Ludlow, Janne Lehtiö, Lukas M. Orre

“…Summary: Farnesylation is a lipid post-translational modification of proteins crucial for protein membrane anchoring and cellular signaling. …”
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Genome-Wide Association Study towards Genomic Predictive Power for High Production and Quality of Milk in American Alpine Goats by Y. Tilahun, T. A. Gipson, T. Alexander, M. L. McCallum, P. R. Hoyt

“…Candidate genes associated differently for each of the following phenotypic traits: test day milk yield (13,469 candidate genes), test day protein yield (25,690 candidate genes), test day fat yield (25,690 candidate genes), percentage protein (25,690 candidate genes), percentage fat (25,690 candidate genes), and percentage lactose content (25,690 candidate genes). …”
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Altering the intracellular trafficking of Necator americanus GST-1 antigen yields novel hookworm mRNA vaccine candidates. by Athos Silva De Oliveira, Leroy Versteeg, Neima Briggs, Rakesh Adhikari, Maria Jose Villar, JeAnna R Redd, Peter Hotez, Maria Elena Bottazzi, Jeroen Pollet

“…This study explores the development of mRNA vaccine candidates based on Na-GST-1, building on the success of recombinant Na-GST-1 (rNa-GST-1) protein, currently assessed as a subunit vaccine candidate, which has shown promise in preclinical and clinical studies.…”
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DYNAMICS OF HAEMATOLOGICAL AND FUNCTIONAL PARAMETERS OF PEKIN DUCK BLOOD DURING ADMINISTRATION OF ORGANIC SELENIUM PREPARATION by Ye. O. Anisimova, V. V. Pronin, L. V. Kletikova, N. N. Yakimenko

“…Biochemical blood analysis included the following parameters: total protein, albumin, uric acid, glucose, calcium, phosphorus, ALT and AST transaminase. …”
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Exploring the Gating Mechanism of the Human Copper Transporter, hCtr1, Using EPR Spectroscopy by Shahaf Peleg, Shelly Meron, Yulia Shenberger, Lukas Hofmann, Lada Gevorkyan-Airapetov, Sharon Ruthstein

“…Moreover, this phenomenon was observed for both reconstituted protein in micelles and in native cell membranes. …”
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Management of Recurrent Ventriculoperitoneal Shunt Infections in Adult Patients by Neval Elgormus, Yusuf Elgormus, Bagnu Dundar, Fatma Bozkurt, Huseyin Dogu, Hafize Uzun

“…Central nervous system (CNS) tuberculosis as the etiology of hydrocephalus; short duration of antibiotics used for treatment; high cerebrospinal fluid (CSF) protein and blood C-reactive protein (CRP) levels; and prolonged use of prophylactic antibiotics were found to be related to an increased rate of recurrent infection occurrence. …”
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Grain of Hybrids Between Spelt ( Triticum spelta L.) and Bread Wheat ( Triticum aestivum L.) as a New Raw Material for Breadmaking by Marian Wiwart, Anna Szafrańska, Elżbieta Suchowilska

“…Analyzed dough parameters in hybrid lines assumed intermediate values relative to parental forms, and protein parameters had a stronger discriminatory power than starch parameters. …”
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Problems of creating antibody phage libraries and their solutions by V. S. Aripov, N. V. Volkova, A. A. Ilyichev, D. N. Shcherbakov

“…Phage display has become an efficient, reliable and popular molecular technique for generating libraries encompassing millions or even billions of clones of divergent peptides or proteins. The method is based on the correspondence between phage genotype and phenotype, which ensures the presentation of recombinant proteins of known amino acid composition on the surface of phage particles. …”
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Dapagliflozin inhibits ferroptosis to improve chronic heart failure by regulating Nrf2/HO-1/GPX4 signaling pathway. by Jing Zhang, Xuefeng Chen, Shilin Lv, Qingqing Hao

“…Dapagliflozin also decreased cardiac iron ion levels and increased Nrf2, HO-1 and GPX4 protein expression.<h4>Conclusion</h4>Dapagliflozin can improve heart failure by inhibiting oxidative stress and ferroptosis, and its mechanism may be related to the regulation of Nrf2/HO-1/GPX4 signaling pathway.…”
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The Effect of Age on the Regenerative Potential of Human Eyelid Adipose-Derived Stem Cells by Mingqi Zhang, Zhuoshi Wang, Yan Zhao, Lirong Zhang, Ling Xu, Liu Cao, Wei He

“…For each group, the proliferative capacity, colony-forming ability, surface markers, differentiation ability, wound healing function, and secreted protein were contrastively evaluated and quantified for statistical analysis. …”
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Characterizing temporal and global host innate immune responses against SARS-CoV-1 and -2 infection in pathologically relevant human lung epithelial cells. by Vivian Y Tat, Aleksandra K Drelich, Pinghan Huang, Kamil Khanipov, Jason C Hsu, Steven G Widen, Chien-Te Kent Tseng, George Golovko

“…., bone marrow stromal cell antigen 2 (BST2), Z-DNA Binding Protein 1 (ZBP1), C-X-C Motif Chemokine Ligand 11 (CXCL11), and Interferon Induced Transmembrane Protein 1 (IFITM1), were identified as potential drug targets against β-CoVs. …”
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Determination of protective effectiveness of nerium oleander distillation in doxorubicin-induced organ damages by Burak Dik, Ayşe Er, Orhan Çorum

“…Doxorubicin decreased (P<0.05) serum total protein and albumin levels compared to Control group, while Doxorubicin + NO distillate increased (P<0.05) aspartate aminotransferase and blood urea nitrogen levels and decreased (P<0.05) total protein, albumin and creatinine levels.…”
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Interleukin-6 related signaling pathways as the intersection between chronic diseases and sepsis by Jie Yang, Lin Yang, Yanjiao Wang, Lu Huai, Bohan Shi, Di Zhang, Wei Xu, Di Cui

“…IL-6 related signaling pathways were sought in Kyoto Encyclopedia of Genes and Genomes (KEGG), and retrieved protein-protein interaction in the Search for Interaction Genes tool (STRING). …”
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ANGPTL4 Attenuates Ang II-Induced Atrial Fibrillation and Fibrosis in Mice via PPAR Pathway by Xi Zhu, Xiaogang Zhang, Xinpeng Cong, Luoning Zhu, Zhongping Ning

“…Mechanistically, ANGPTL4 inhibited the activation of several fatty acid metabolism-related proteins, including PPARα, PPARγ, and CPT-1, and the expression of SIRT3 protein in atrial tissues. …”
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An In Vitro Study on Prestin Analog Gene in the Bullfrog Hearing Organs by Zhongying Wang, Minfei Qian, Qixuan Wang, Huihui Liu, Hao Wu, Zhiwu Huang

“…It is densely expressed in the OHC lateral plasma membrane and functions as a voltage-dependent motor protein. Analog genes can be found in the genome of nonmammalian species, but their functions in hearing are poorly understood. …”
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Anticolitic Effect of Berberine in Rat Experimental Model: Impact of PGE2/p38 MAPK Pathways by Li Jia, Kuijin Xue, Junheng Liu, Ola A. Habotta, Lianhai Hu, Ahmed E. Abdel Moneim

“…Furthermore, BER exhibited noticeable antiapoptotic activities through decreasing proapoptotic proteins (Bax and caspase-3) and lessening antiapoptotic Bcl-2 protein in the colon mucosa. …”
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MRP8/ABCC11 Expression Is Regulated by Dexamethasone in Breast Cancer Cells and Is Associated to Progesterone Receptor Status in Breast Tumors by Mylène Honorat, Aurélia Mesnier, Julie Vendrell, Attilio Di Pietro, Valérie Lin, Charles Dumontet, Pascale Cohen, Léa Payen

“…The ATP-binding cassette multidrug resistance protein 8 (MRP8/ABCC11) mediates the excretion of anticancer drugs. …”
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Metabolic diseases in cattle by V. A. Mischenko, A. V. Mischenko, R. V. Yashin, V. A. Yevgrafova, T. B. Nikeshina

“…Metabolic disorders in highly productive cows occur as a result of unbalanced diets as far as protein, carbohydrates, vitamins and minerals are concerned. …”
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