Selected Parameters of Nutritional and Pro-Health Value in the Common Carp (Cyprinus carpio L.) Muscle Tissue by J. Kłobukowski, K. Skibniewska, K. Janowicz, F. Kłobukowski, E. Siemianowska, E. Terech-Majewska, J. Szarek

“…The type of production technology, especially the intensive breeding technique, has been shown to have a significant effect on dry weight, total protein, and total fat content in the common carp muscle tissue under study. …”
Get full text

Hipoksi ve Kanser by Sümeyye Aydogan Türkoğlu, Fatma Poyrazlı, Derya Babacan, Feray Köçkar

“…Hücrelerdeki hipoksinin moleküler mekanizmasından sorumlu temel protein ailesi HIF (Hipoksi ile İndükelenebilir Faktör)’ dir. …”
Get full text

Increased nuclear expression of DNA damage inducible transcript 4 can serve as a potential prognostic biomarker in patients with gliomas: a study based on data mining and experimen... by Alireza Sadeghipour, Fahimeh Fattahi, Zahra Madjd, Fatemeh Tajik, Farnoosh Sedaghati, Leili Saeednejad Zanjani

“…To validate these findings, DDIT4 protein expression levels and their prognostic significance were examined in tissue microarrays from glioma patients using immunohistochemistry in clinical samples. …”
Get full text

Depletion and Reversal of Hepatocellular Carcinoma Inducing CTL through ER Stress-Dependent PERK-CHOP Signaling Pathway by Mengnan Guo, Wei Wang, Wen Bai, Zekun Bai, Weixi Chen, Yali Su, Jinghua Wu

“…Moreover, perforin (PRF1) and granzyme B (GzmB) protein levels and ER morphology were examined by ELISA and TEM, respectively. …”
Get full text

Starvation-induced metabolic rewiring affects mTORC1 composition in vivo by Edgar Kaade, Simone Mausbach, Nina Erps, Marc Sylvester, Farhad Shakeri, Ron D. Jachimowicz, Volkmar Gieselmann, Melanie Thelen

“…Proteasomal, cytosolic and peroxisomal proteins dominated after short-term starvation, while after long-term starvation, mainly proteasomal and mitochondrial proteins accumulated, indicating ordered autophagic protein degradation.…”
Get full text

Analysis of somatic piRNAs in the malaria mosquito Anopheles coluzzii reveals atypical classes of genic small RNAs by Sergei Funikov, Alexander Rezvykh, Natalia Akulenko, Jiangtao Liang, Igor V. Sharakhov, Alla Kalmykova

“…By contrast, majority of protein-coding gene-derived 24-32 nt small RNAs lack the hallmarks of piRNAs and have signatures of nontemplated 3’ end tailing. …”
Get full text

Use of Graph Database for the Integration of Heterogeneous Biological Data by Byoung-Ha Yoon, Seon-Kyu Kim, Seon-Young Kim

“…We collected various biological data (protein-protein interaction, drug-target, gene-disease, etc.) from several existing sources, removed duplicate and redundant data, and finally constructed a graph database containing 114,550 nodes and 82,674,321 relationships. …”
Get full text

Relationship of Nitrogen Use Efficiency with the Activities of Enzymes Involved in Nitrogen Uptake and Assimilation of Finger Millet Genotypes Grown under Different Nitrogen Inputs by Nidhi Gupta, Atul K. Gupta, Vikram S. Gaur, Anil Kumar

“…However, the crude grain protein content was higher in PRM-801 genotype followed by PRM-701 and PRM-1, indicating negative correlation of nitrogen use efficiency with source to sink relationship in terms of seed protein content.…”
Get full text

A Possible Role of HMGB1 in DNA Demethylation in CD4+ T Cells from Patients with Systemic Lupus Erythematosus by Yaping Li, Chenghui Huang, Ming Zhao, Gongping Liang, Rong Xiao, Susan Yung, Tak Mao Chan, Qianjin Lu

“…In this study, we identified proteins that bind to Gadd45a in CD4+ T cells during SLE flare by using the method of co-immunoprecipitation and mass spectrometry, High mobility group box protein 1 (HMGB1) is one of identified proteins. …”
Get full text

Lysosome and Cytoskeleton Pathways Are Robustly Enriched in the Blood of Septic Patients: A Meta-Analysis of Transcriptomic Data by Jie Ma, Chuanxi Chen, Andreas S. Barth, Chris Cheadle, Xiangdong Guan, Li Gao

“…Overall, our study revealed distinct mRNA activation profiles and protein-protein interaction networks in blood of human sepsis. …”
Get full text

A New Functional Model for Prediction of Chaperone Activity of the Recombinant M. tb Acr (α-Crystallin) Using Insulin as Substrate by Gautam Krishnan, Utpal Roy

“…Mycobacterium tuberculosis Acr is an important protein expressed in latent tuberculosis which is active as an oligomer in preventing misfolding of cellular proteins. …”
Get full text

The Use of Perovskia abrotanoides Extract in Ameliorating Heat Stress-Induced Oxidative Damage and Improving Growth Efficiency in Carp Juveniles (Cyprinus carpio) by Hossein Adineh, Saeed Zahedi, Morteza Yousefi, Zeynab Sedaghat, Sevdan Yilmaz, Ebrahim Gholamalipour Alamdari, Mohammad Farhangi

“…Moreover, serum total protein, albumin, and total immunoglobulin levels as well as ACH50, lysozyme, superoxide dismutase, and glutathione peroxidase activities were increased before and/or after high-temperature stress (32°C). …”
Get full text

Correlation between Exclusive Breastfeeding, Complementary Feeding, Infectious Disease with Wasting among Toddlers: a Cross-Sectional Study by Ani Intiyati, Rany Dwi Yuliana Putri, Imam Sarwo Edi, Taufiqurrahman Taufiqurrahman, Inne Soesanti, Nuning Marina Pengge, Dian Shofiya

“…Conclusions: While exclusive breastfeeding tends to reduce wasting, appropriate CF and adequate intake of energy, protein, fat, and carbohydrates are associated with a lower prevalence of wasting. …”
Get full text

Proton Pump Inhibitors and Dementia: Physiopathological Mechanisms and Clinical Consequences by Gloria Ortiz-Guerrero, Diana Amador-Muñoz, Carlos Alberto Calderón-Ospina, Daniel López-Fuentes, Mauricio Orlando Nava Mesa

“…Although neurological side effects secondary to PPIs are rare, several preclinical reports indicate that PPIs might increase Aβ levels, interact with tau protein, and affect the neuronal microenvironment through several mechanisms. …”
Get full text

A computational tool to infer enzyme activity using post-translational modification profiling data by Dehui Kong, Aijun Zhang, Ling Li, Zuo-Fei Yuan, Yingxue Fu, Long Wu, Ashutosh Mishra, Anthony A. High, Junmin Peng, Xusheng Wang

“…Despite their crucial roles, measuring enzyme activities is typically indirect and performed on a smaller scale, unlike protein abundance measured by high-throughput proteomics. …”
Get full text

Roles of retinoic acid-related orphan receptor α in high glucose-induced cardiac fibroblasts proliferation by Wenqing San, Qianyou Zhou, Danning Shen, Danyi Cao, Yun Chen, Guoliang Meng

“…Expressions of Collagen I, Collagen III, proliferating cell nuclear antigen (PCNA), α-smooth muscle actin (α-SMA), receptor-interacting protein kinase 1 (RIPK1) and receptor-interacting protein kinase 3 (RIPK3) were evaluated. …”
Get full text

Impact of Hypocaloric Diets on Weight Loss and Body Composition in Obese Dogs: A Meta-Analysis by Karoline Vanelli, Rafael Fernando Wisneski, Camila Estevão, Fernanda Caroline Mayer, Leandro Batista Costa, Saulo Henrique Webber, Cláudia Turra Pimpão

“…This meta-analysis provides evidence-based nutritional recommendations on optimal caloric, protein, fiber, fat, and carbohydrate levels for hypocaloric diet formulations, supporting healthy weight loss and lean mass preservation in obese dogs. …”
Get full text

Potential Role of ANGPTL4 in the Cross Talk between Metabolism and Cancer through PPAR Signaling Pathway by Laura La Paglia, Angela Listì, Stefano Caruso, Valeria Amodeo, Francesco Passiglia, Viviana Bazan, Daniele Fanale

“…The angiopoietin-like 4 (ANGPTL4) protein belongs to a superfamily of secreted proteins structurally related to factors modulating angiogenesis known as angiopoietins. …”
Get full text

A Nonsynonymous Single-nucleotide Polymorphism in SLC24A5 Regulates Feather Pigment Deposition in Chinese Yellow Quail by Xiaohui Zhang, Fanghu Wu, Yanxia Qi, Yuanyuan Shang, Lingyun Fan, Yifei Wang

“…The mutant residue was predicted to be located inside the eighth transmembrane helix of the SLC24A5 protein, which is primarily responsible for recognizing Na+/Ca2+ ions. …”
Get full text

Mutations in Homocysteine Metabolism Genes Increase Keratin N-Homocysteinylation and Damage in Mice by Kamila Borowczyk, Jacek Wróblewski, Joanna Suliburska, Noriyuki Akahoshi, Isao Ishii, Hieronim Jakubowski

“…Genetic or nutritional deficiencies in homocysteine (Hcy) metabolism increase Hcy-thiolactone, which causes protein damage by forming isopetide bonds with lysine residues, generating N-Hcy-protein. …”
Get full text