Andrographolide prevents acute hyperammonemia-induced motor dysfunction in rats. Evidences for its mechanism of action by Arghya Mukherjee, Santosh Singh

“…Malondialdehyde (MDA), reduced glutathione (GSH), protein carbonylation levels and activity of superoxide dismutase (SOD), catalase, glutathione peroxidase (GPx), glutathione reductase (GR) were studied as oxidative stress markers. …”
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Physicochemical and Thermal Characteristics of Onion Skin from Fifteen Indian Cultivars for Possible Food Applications by Narashans Alok Sagar, Anil Khar, Vikas, Ayon Tarafdar, Sunil Pareek

“…“NHRDF Red” contained the highest amount of crude protein (5.97 ± 0.15 g/100 g), ash (12.24 ± 0.59 g/100 g), and fiber (8.28 ± 0.20 g/100 g), whereas cv. …”
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Identification of an inter-cysteine loop potentially involved in the activity of Opisthorchis viverrini-granulin-1 by Rozita Takjoo, David T. Wilson, Paramjit S. Bansal, Alex Loukas, Michael J. Smout, Norelle L. Daly

“…Aim: Identification of small bioactive regions in proteins and peptides can be useful information in drug design studies. …”
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The SGLT-2 Inhibitor Dapagliflozin Has a Therapeutic Effect on Atherosclerosis in Diabetic ApoE−/− Mice by Weiling Leng, Xinshou Ouyang, Xiaotian Lei, Mingxia Wu, Liu Chen, Qinan Wu, Wuquan Deng, Ziwen Liang

“…Effects of dapagliflozin on indices of glucose and fat metabolism, IL-1β, IL-18, NLRP3 protein levels, and the reactive oxygen species (ROS) were measured. …”
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EFFICACY OF THIONONTRITE-S FOR PREVENTION OF METABOLIC LIVER DISEASE IN CATTLE by Ye. V. Tyapkina, M. P. Semenenko, Ye. V.  Kuzminova, A. A.  Abramov

“…The use of thiononitrite-S promoted an increase in the protein-synthesizing function of the liver; in particular, an increase in the level of total protein was 8.8% against the baseline indicators in the experimental group. …”
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High serum level of endostatin in multiple myeloma at diagnosis but not in the plateau phase after treatment by Halina Urbanska-Rys, Tadeusz Robak

“…We did not show any statistical correlation between the concentration of endostatin and level of haemoglobin, creatinine, calcium, C-reactive protein, β2-microglobulin and stage of bone disease. …”
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Harnessing the diversity of a lettuce wild relative to identify anthocyanin-related genes transcriptionally responsive to drought stress by Inés Medina-Lozano, Inés Medina-Lozano, Jérôme Grimplet, Jérôme Grimplet, Aurora Díaz, Aurora Díaz

“…Some wild variants had high or moderate predicted impacts on the respective protein function: a transcription factor that responds to abiotic stresses, a heat shock protein involved in stomatal closure, and a phospholipase participating in anthocyanin accumulation under abiotic stress. …”
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Effect of Electric Fields on the Mechanical Mechanism of Regorafenib–VEGFR2 Interaction to Enhance Inhibition of Hepatocellular Carcinoma by Yichen Tian, Fenghui Liao, Heng Sun, Yongrong Lei, Yuna Fu, Feng Xia, Jianhua Wang

“…Electric fields can change the structure of proteins, which determines the interaction between drugs and proteins. …”
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Acupuncture Alleviates CUMS-Induced Depression-Like Behaviors by Restoring Prefrontal Cortex Neuroplasticity by Peng Li, Wenya Huang, Yiping Chen, Muhammad Shahzad Aslam, Wenjing Cheng, Yang Huang, Wenjie Chen, Yanxun Huang, Xinnan Wu, Yining Yan, Junliang Shen, Tao Tong, Shuqiong Huang, Xianjun Meng

“…The prefrontal cortex expression, such as BDNF, PSD95, SYN, and PKMZ protein, was detected using the western blot and RT-PCR. …”
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By-Products of the Babassu Agribusiness for Ruminant Diets by Ygor Nascimento Portela, Danrley Martins Bandeira, Daniele de Jesus Ferreira, Henrique Nunes Parente, Michelle de Oliveira Maia Parente, Ivo Alexandre Leme da Cunha, Glayciane Costa Gois, Fleming Sena Campos, Francisca Claudia da Silva de Sousa, Luana Milena Pinheiro Rodrigues, Jessica Maria de Sousa Oliveira, Anderson de Moura Zanine

“…For the degradation of crude protein, the highest percentages of potential and effective degradability were observed for greasy and 95 µm flour. …”
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Inflammation and ER Stress Downregulate BDH2 Expression and Dysregulate Intracellular Iron in Macrophages by Susu M. Zughaier, Brandon B. Stauffer, Nael A. McCarty

“…We also show that ER stress combined with inflammation synergistically upregulated the expression of the iron carrier protein NGAL and the stress-inducible heme degrading enzyme heme oxygenase-1 (HO-1) leading to iron liberation. …”
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Osteopontin: Relation between Adipose Tissue and Bone Homeostasis by Carolina De Fusco, Antonietta Messina, Vincenzo Monda, Emanuela Viggiano, Fiorenzo Moscatelli, Anna Valenzano, Teresa Esposito, Chieffi Sergio, Giuseppe Cibelli, Marcellino Monda, Giovanni Messina

“…Osteopontin (OPN) is a multifunctional protein mainly associated with bone metabolism and remodeling. …”
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A Reduction in Selenoprotein S Amplifies the Inflammatory Profile of Fast-Twitch Skeletal Muscle in the mdx Dystrophic Mouse by Craig Robert Wright, Giselle Larissa Allsopp, Alex Bernard Addinsall, Natasha Lee McRae, Sofianos Andrikopoulos, Nicole Stupka

“…The mdx:Seps1−/+ mice had a 50% reduction in SEPS1 protein expression in hindlimb muscles. In the extensor digitorum longus (EDL) muscles, mRNA expression of monocyte chemoattractant protein 1 (Mcp-1) (P=0.034), macrophage marker F4/80 (P=0.030), and transforming growth factor-β1 (Tgf-β1) (P=0.056) were increased in mdx:Seps1−/+ mice. …”
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Exploring the Molecular Composition of Dissolved Organic Matter and Its Connection to Microbial Communities in Industrial-Scale Anaerobic Digestion of Chicken Manure by Juan Hu, Yurui Zeng, Aibin Hu, Xiaofeng Wang

“…The results revealed that the DOM contained abundant free amino acids and protein-like compounds but fewer humic-like substances, identified as lignin/carboxylate-rich alicyclic molecules, lipids, and proteins/aliphatic compounds featuring enriched S_5–6O₁ and N_1–5O_X fragments. …”
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Multiple Components of the VHL Tumor Suppressor Complex Are Frequently Affected by DNA Copy Number Loss in Pheochromocytoma by David A. Rowbotham, Katey S. S. Enfield, Victor D. Martinez, Kelsie L. Thu, Emily A. Vucic, Greg L. Stewart, Kevin L. Bennewith, Wan L. Lam

“…Our results indicate that VHL elongin BC protein complex components other than VHL could be important for PCC tumorigenesis and merit further investigation.…”
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Connexin 43 Communication Channels in Follicular Dendritic Cell Development and in Follicular Lymphomas by Hajnalka Rajnai, Ivett Teleki, Gergo Kiszner, Nora Meggyesházi, Peter Balla, Tamas Vancsik, Gyorgyi Muzes, Judit Csomor, Andras Matolcsy, Tibor Krenacs

“…In culture, the treatment of FDC-B cell clusters (resembling to “ex vivo” germinal centers) with Gap27 peptide, mimicking the 2nd extracellular loop of Cx43 protein, significantly impaired FDC-B cell cluster formation and cell survival. …”
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Using Milk Urea Nitrogen to Evaluate Diet Formulation and Environmental Impact on Dairy Farms by J.S. Jonker, R.A. Kohn

“…N loading to the Chesapeake Bay from overfeeding protein to lactating dairy cattle was estimated to be 7.6 million kg/year. …”
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Fermented soy whey induced changes on intestinal microbiota and metabolic influence in mice by Wei Han, Xuhui Zhuang, Qian Liu, Bo Sun, Haijiang Miao, Xiaolin Zhang

“…Soy whey (SW) is generated as process waste while preparing soy protein isolates (SPI), and causing severe environmental pollution. …”
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Potential of Inducible Nitric Oxide Synthase as a Therapeutic Target for Allergen-Induced Airway Hyperresponsiveness: A Critical Connection to Nitric Oxide Levels and PARP Activity by Salome’ V. Ibba, Mohamed A. Ghonim, Kusma Pyakurel, Matthew R. Lammi, Anil Mishra, A. Hamid Boulares

“…Here, we confirm iNOS expression in the asthmatic lung with concomitant protein nitration and poly(ADP-ribose) polymerase (PARP) activation. …”
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Methylation Status of Vitamin D Receptor Gene Promoter in Benign and Malignant Adrenal Tumors by Catia Pilon, Andrea Rebellato, Riccardo Urbanet, Vincenza Guzzardo, Rocco Cappellesso, Hironobu Sasano, Ambrogio Fassina, Francesco Fallo

“…We previously showed a decreased expression of vitamin D receptor (VDR) mRNA/protein in a small group of adrenocortical carcinoma (ACC) tissues, suggesting the loss of a protective role of VDR against malignant cell growth in this cancer type. …”
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