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4061
Investigating the reassortment potential and pathogenicity of the S segment in Akabane virus using a reverse genetics system
Published 2025-01-01“…Conclusions These observations suggest that the S segment, especially the NS protein, is associated with the pathogenicity of AKAV-7. …”
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4062
Functional Characterization of Sesquiterpene Synthase from Polygonum minus
Published 2014-01-01“…It also consists of three conserved motifs: the DDXXD, NSE/DTE, and RXR. A three-dimensional protein model for PmSTS built clearly distinguished the two main domains, where conserved motifs were highlighted. …”
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4063
Cyanin Chloride Inhibits Hyperbaric Pressure-Induced Decrease of Intracellular Glutamate-Aspartate Transporter in Rat Retinal Müller Cells
Published 2018-01-01“…Cell survival rates (SRs) were evaluated by an MTT assay. GLAST mRNA and protein expression were determined by western blot and RT-PCR analyses, respectively. …”
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4064
Necrotizing Liver Granuloma/Abscess and Constrictive Aspergillosis Pericarditis with Central Nervous System Involvement: Different Remarkable Phenotypes in Different Chronic Granul...
Published 2017-01-01“…A 16-year-old boy with a mutation in CYBB gene coding gp91phox protein (X-linked disease) developed a liver abscess due to Staphylococcus aureus. …”
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4065
Comprehensive Bioinformatics Method to Explore Immune-Related Genes in the Pathogenesis of Myocardial Infarction
Published 2025-01-01“…We performed differential gene expression analysis, GO/KEGG enrichment analysis, protein-protein interaction (PPI) network analysis, weighted gene co-expression network analysis (WGCNA), gene set enrichment analysis, and immune infiltration studies to identify core immune-related genes associated with MI. …”
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4066
Comparison of the Nutritional and Taste Characteristics of 5 Edible Fungus Powders Based on the Composition of Hydrolyzed Amino Acids and Free Amino Acids
Published 2022-01-01“…Comparative analysis of the mass fractions and composition of amino acids indicated that Pleurotus citrinopileatus edible fungus powder best met the ideal protein standard. The taste characteristics of protein were evaluated by calculating the taste active value (TAV) of taste-producing free amino acids. …”
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4067
The Latest Developments and Future Trends of Australian Food Industry under the Concept of Sustainability
Published 2025-01-01“…It also plays a role of food processing to improve food safety and sustainability, absorbing digital transformation technology, 5G, Artificial Intelligence, alternative protein and food safety technology innovation. It vigorously develops plant-based foods, space foods and marine foods, etc. …”
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4068
Identification of an ethylene-responsive and cell wall-secreting β-1,3-glucanase, VvGLU1, in the early cell regrowth of grape winter buds triggered by exogenous dormancy releasers
Published 2025-01-01“…Among these, VvGLU1 presented increased gene transcription and protein expression in response to HC and ethylene treatment. …”
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4069
Magnesium Lithospermate B Downregulates the Levels of Blood Pressure, Inflammation, and Oxidative Stress in Pregnant Rats with Hypertension
Published 2020-01-01“…The effects of MLB on mean arterial blood pressure (MAP), urine protein level, inflammation, and oxidative stress together with angiogenesis were analyzed. …”
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4070
Metastatic melanoma: An integrated analysis to identify critical regulators associated with prognosis, pathogenesis and targeted therapies.
Published 2025-01-01“…After exploration of DEGs of NS and metastatic-melanoma, identification of relevant transcription factors (TFs) and kinases, the Gene Ontology (GO), and pathways analyses of DEGs were performed. Protein-protein interaction (PPI) networks were evaluated by the STRING and Cytoscape. …”
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4071
Primary Signet Ring Cell/Histiocytoid Carcinoma of the Eyelid: Clinicopathologic Analysis with Evaluation of the E-Cadherin/β-Catenin Complex and Associated Genetic Alterations
Published 2021-01-01“…The CDH1 gene, which encodes the E-cadherin protein, is the best known gene associated with these tumors. …”
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4072
Network Pharmacology Reveals Polyphyllin II as One Hit of Nano Chinese Medicine Monomers against Nasopharyngeal Carcinoma
Published 2021-01-01“…Gene Ontology (GO) function enrichment analysis showed that biological processes and functions mainly concentrated on apoptotic process, protein phosphorylation, cytosol, protein binding, and ATP binding. …”
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4073
Evolutionary Insights into IL17A in Lagomorphs
Published 2015-01-01“…We observed that this protein is highly conserved between these species, with a similarity of 97–99% in leporids and ~88% between leporids and American pika. …”
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4074
Papaverine Enhances the Oncolytic Effects of Newcastle Disease Virus on Breast Cancer In Vitro and In Vivo
Published 2023-01-01“…Evaluation of the antitumor activity included growth inhibition measurement; the immunohistochemistry assay measured caspase protein expression. Finally, a semiquantitative microarray assay was used to screen changes in apoptotic proteins. …”
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4075
Proteomic Profiling Towards a Better Understanding of Genetic Based Muscular Diseases: The Current Picture and a Look to the Future
Published 2025-01-01“…Proteomics accelerates diagnosis and research of muscular diseases by enabling the robust analysis of proteins relevant for the manifestation of neuromuscular diseases in the following aspects: (i) evaluation of the effect of genetic variants on the corresponding protein, (ii) prediction of the underlying genetic defect based on the proteomic signature of muscle biopsies, (iii) analysis of pathophysiologies underlying different entities of muscular diseases, key for the definition of new intervention concepts, and (iv) patient stratification according to biochemical fingerprints as well as (v) monitoring the success of therapeutic interventions. …”
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4076
Genome biology of long non-coding RNAs in humans: A virtual karyotype
Published 2025-01-01“…Additionally, we observed that lncRNAs generally exhibit shorter gene lengths and fewer splicing variants compared to protein-coding transcripts, with a subset displaying pronounced clustering patterns that may indicate functional relevance. …”
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4077
Novel cycloviruses identified by mining human blood metagenomic data show close relationship to those from animals
Published 2025-01-01“…We used viral metagenomics to mine, analyze, and visualize the human blood virome, successfully identifying three new genomes, each encoding Rep and Capsid proteins. These proteins are crucial for viral replication and host-cell interaction: the Rep protein is involved in initiating viral genome replication, while the Capsid protein plays a key role in the assembly of new virions and the virus's ability to interact with host immune systems. …”
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4078
Cellular Composition Changes and Nitrogen Uptake under Extra-Limited Nitrogen Conditions by Thermosynechococcus sp. CL-1 Carbon Biofixation
Published 2016-01-01“…The lipid, carbohydrate, and protein cellular components which can be used as bioenergy precursors along with their content as a function of various C/N ratios are quantified. …”
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4079
Comparison of the evolutionary patterns of DNA repeats in ancient and young invertebrate species flocks of Lake Baikal
Published 2023-07-01“…The topology of this tree was compared to the phylogenies inferred for the same species from the concatenated protein-coding mitochondrial nucleotide sequences. …”
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4080
High Throughput Approaches to Unravel the Mechanism of Action of a New Vanadium-Based Compound against Trypanosoma cruzi
Published 2020-01-01“…Instead, proteomic analysis uncovered the modulation of proteins involved in different processes such as energy and redox metabolism, transport systems, detoxifying pathways, ribosomal protein synthesis, and proteasome protein degradation. …”
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