Application of a sourdough type-II fermentation model to gelatinized legume flours: Starter robustness, technological and nutritional implications, potential of the bread and pasta... by Marco Montemurro, Giuseppe Perri, Michela Verni, Erica Pontonio, Carlo Giuseppe Rizzello

“…The results showed that sourdough fermentation positively influenced the biochemical properties of fortified foods, leading to improved protein digestibility and a lower predicted glycemic index. …”
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ER Stress and Iron Homeostasis: A New Frontier for the UPR by Susana J. Oliveira, Maria de Sousa, Jorge P. Pinto

“…The conformational changes introduced by this mutation impair the HFE association with β2-microglobulin (β2m) and the cell surface expression of the protein: with two major consequences. From a functional perspective, the ability of HFE to bind to transferrin receptors 1 and 2 is lost in the C282Y mutant, thus affecting hepcidin regulation. …”
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Complete Sequence and Characterization of Mitochondrial and Chloroplast Genome of <i>Navicula incerta</i> CACC 0356 by Zhaokai Wang, Xiaoyu Wei

“…The mitochondrial genome (mtDNA) spans 61,320 bp with a GC content of 29.87%, comprising one circular DNA molecule that encodes for 34 protein-coding genes, 24 tRNAs, and 34 rRNAs. Whereas, the chloroplast genome (cpDNA) is larger at 129,090 bp, encompassing 127 protein-coding genes, 30 tRNAs, and 7 rRNAs. …”
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Effect of Ecotype and Latitude on Growth, Frost Hardiness, and Oxidative Stress of South to North Transplanted Scots Pine Seedlings by Erja Taulavuori, Kari Taulavuori, Ahti Niinimaa, Kari Laine

“…Shoot elongation, total nitrogen concentration, frost hardiness and oxidative stress state (lipid peroxidation, glutathione reductase activity, and protein oxidation) in the needles were analyzed. Comparison between the seasonal sampling times indicated that total nitrogen, lipid peroxidation, glutathione reductase activity, and protein oxidation were lower in autumn, during which the frost hardiness was higher. …”
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Immunological Approaches and Different Strategies for Vaccine Development Against SARS-COV-2 by Muhammed Babakir-Mina

“…Moreover, there are different strategies that used by researchers and pharmacological companies to develop vaccines including attenuated or killed viruses, RNA of a spike protein, and vector expressing a particular protein of the virus. …”
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Carvedilol Confers Ferroptosis Resistance in HL-1 Cells by Upregulating GPX4, FTH1, and FTL1 and Inducing Metabolic Remodeling Under Hypoxia/Reoxygenation by Yi-Chin Li, Mei-Ling Cheng

“…The study found that Carvedilol upregulated glutathione peroxidase 4 (GPX4) protein expression to resist HR-induced lipid peroxidation by metabolic remodeling under HR. …”
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Unconventional secretion of unglycosylated ORF8 is critical for the cytokine storm during SARS-CoV-2 infection. by Xiaoyuan Lin, Beibei Fu, Yan Xiong, Na Xing, Weiwei Xue, Dong Guo, Mohamed Zaky, Krishna Pavani, Dusan Kunec, Jakob Trimpert, Haibo Wu

“…In addition to structural proteins such as Spike and Envelope, the functional roles of non-structural and accessory proteins in regulating viral life cycle and host immune responses remain to be understood. …”
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Protective Effect of Fermented Camel Milk Containing Bifidobacterium longum BB536 on Blood Lipid Profile in Hypercholesterolemic Rats by Khaled M. El-Zahar, Mohamed F. Y. Hassan, Suliman F. Al-Qaba

“…All fermented milk products significantly reduced HDL, albumin, and total protein. The percentage change in body weight gain was between −40% (CAP) and −24% (CT) and in serum triglycerides between −54% (CCAP) and −37% (CT); for the other parameters, changes caused by CCAP/CT were −40%/−22% (total cholesterol), +29%/+8% (HDL), −73%/−54% (LDL), −54%/−37% (VLDL), −52%/−14% (AST), −53%/−31% (ALT), +43%/+25% (albumin), +37%/+25% (total protein), −48%/−27% (urea), and −34%/−16% (creatinine). …”
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Modulatory effects of rutin on the expression of cytochrome P450s and antioxidant enzymes in human hepatoma cells by Karakurt Sedar

“…Treatment by rutin significantly inhibited protein expressions of cytochrome P450-dependent CYP3A4 (75.3 %, p < 0.0001), elevated CYP1A1 enzymes (1.7-fold, p = 0.0084) and increased protein expressions of antioxidant and phase II reaction catalyzing enzymes, NQO1 (2.42-fold, p < 0.0001) and GSTP1 (2.03-fold, p < 0.0001). …”
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Effect Of Tamarillo (Solanum Betaceum Cav.) Addition On Physical And Chemical Characteristics Of Yoghurt Produced by Novelina Novelina

“…The results showed that the addition of tamarillo juice to yoghurt had a significant effect on viscosity, color, fat content, ash content, total solids, total lactic acid, and Organoleptic test (color, aroma, taste and consistency), but had no significant effect on protein content, pH value and total lactic acid bacteria. …”
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Renal function in Ankylosing Spondylitis by Renu Saigal, Arun Kumar Agrawal, Laxmikant Goyal, Abhishek Agrawal, Naveen Gupta

“…Disease activity was assessed using Bath Ankylosing Spondylitis Disease Activity Index, Bath Ankylosing Spondylitis Functional Index, Bath Ankylosing Spondylitis Metrology Index scores, C-reactive protein, and erythrocyte sedimentation rate. Results: Among AS cases, 31 AS cases (77.50%) had renal function abnormalities including hematuria (20%), proteinuria (30%), albuminuria (52.50%), increased 24 h urine protein (22%), raised serum creatinine (17%), and reduced glomerular filtration rate (GFR) (37%). …”
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The Role of the Enterohepatic Circulation of Bile Salts and Nuclear Hormone Receptors in the Regulation of Cholesterol Homeostasis: Bile Salts as Ligands for Nuclear Hormone Recept... by Richard N Redinger

“…It is the coordinated action of LXR and FXR, each dimerized to retinoid X receptor, that signal nuclear DNA response elements to encode proteins that prevent excessive cholesterol accumulation and bile salt toxicity, respectively. …”
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Conformational Dynamics of Mitochondrial Inorganic Pyrophosphatase hPPA2 and Its Changes Caused by Pathogenic Mutations by Ekaterina Bezpalaya, Svetlana Kurilova, Nataliya Vorobyeva, Elena Rodina

“…The results of this work allow for deeper insight into the structural basis of PPase function and the possible effects of pathogenic mutations on the protein structure and function.…”
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Prion Diseases and the Gastrointestinal Tract by Gwynivere A Davies, Adam R Bryant, John D Reynolds, Frank R Jirik, Keith A Sharkey

“…Although normal cellular prion protein is found in the enteric nervous system, its role has not been characterized. …”
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Lawsonia intracellularis T3SS effector LI0758, an Rce1 ortholog, activates MAPK and NF-κB signaling in mammalian cells by Yuanxiu Zhong, Yiyun Duan, Fenju Lai, Jinhua Zhang, Yimin Dai

“…Bioinformatics analyses indicate that LI0758 is an ortholog of Rce1, a eukaryotic CAAX protein endoprotease, sharing a similar subcellular localization on the endoplasmic reticulum (ER). …”
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Differentially Expressed Genes Study Shown Potential for BCG Stimulation in Reducing the Severity of COVID-19 by Irandi Putra Pratomo, Aryo Tedjo, Dimas R Noor, Wisnu Ananta Kusuma

“…The Gene Expression Omnibus (GEO) database was used to select a COVID-19 gene expression data set with GSE164805, GSE14408, and GSE58636, and DEG in each data set were identified using the GEO2R online tools and selected using the adjusted p value (padj) 0.05 criteria. The protein-protein interaction (PPI) network was constructed from DEGs with the same trend of expression (upregulation or downregulation) using STRING version 11. …”
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The NLRP3 Inflammasome as a Novel Player of the Intercellular Crosstalk in Metabolic Disorders by Elisa Benetti, Fausto Chiazza, Nimesh S. A. Patel, Massimo Collino

“…One of the most recently identified signaling pathways, whose activation seems to affect many metabolic disorders, is the “inflammasome,” a multiprotein complex composed of NLRP3 (nucleotide-binding domain and leucine-rich repeat protein 3), ASC (apoptosis-associated speck-like protein containing a CARD), and procaspase-1. …”
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Possible involvement of vitamin K insufficiency in the progression of cervical ossification of the posterior longitudinal ligament by Atsushi Kimura, Naoya Taki, Yukinori Hayashi, Yasuyuki Shiraishi, Tsukasa Ohmori, Katsushi Takeshita

“…Those with OPLL had significantly longer prothrombin times and lower plasma protein C concentrations, consistent with vitamin K deficiency. …”
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Performance and Genetic Variability of Okra (Abelmoschus esculentus (L.) Moench) Genotypes in Ethiopia for Agromorphology and Biochemical Traits by Jemal Mohammed, Wassu Mohammed, Eleni Shiferaw

“…Genotypic coefficients of variation and phenotypic coefficient of variation were high for number of branches, internode length, fresh fruit weight, number of mature pods, fruit yield per plant, fruit yield per hectare, seed yield per plant, seed yield per hectare, and seed protein content. Heritability values ranged between 33.63 and 99.81%, while the genetic advance as percentage of mean ranged between 4.29 and 95.45%. …”
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Diagnosis of bovine viral diarrhea in Bubalus bubalis dairy farms by Oriana Gavidia, Rosaura Pérez-Gil

“…The seropositive results for the non-structural protein p80, in general, were 55.76%. In the group of buffaloes with low milk yield, 54.54% were positive, while in the group with high milk yield, 53.33% were positive, with no significant  differences between animal groups (p>0.05). …”
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