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3681
Electrostatic properties of human germlines and biodistribution of small biologics
Published 2024-12-01“…Renal and hepatic uptakes are known to be affected by protein electrostatics, which promote protein internalization through pinocytosis. …”
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3682
The role of transposable elements in the ecological morphogenesis under the influence of stress
Published 2019-07-01“…Transposons are sources of non-coding RNA, transcription factors binding sites and protein-coding genes due to domestication, exonization, and duplication. …”
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3683
The Use of Antisense-Mediated Inhibition to Delineate The Role of Inflammatory Agents in The Pathophysiology of Spinal Cord Injury
Published 2002-01-01“…Hybridization of the oligonucleotide to the mRNA then interferes with the normal processing of that mRNA at the ribosome or targets the RNA duplex for cleavage by the RNA digestive enzyme, ribonuclease H, resulting in greatly reduced expression of the coded protein. This effectively reduces the amount of corresponding translated protein product and experiments can be designed to examine the requirement of particular inflammatory agents in eliciting specific deleterious responses after injury, e.g., cell death.…”
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3684
A Critical Review on Tropical Fruits Seeds as Prospective Sources of Nutritional and Bioactive Compounds for Functional Foods Development: A Case of Indonesian Exotic Fruits
Published 2020-01-01“…The seeds contain essential bioactive components, such as polyphenols, flavonoids, phenolic acid, and carotenoids, that exhibit excellent antioxidant activity, fats that have remarkable physicohemical properties (free of trans-fatty acids), and a high protein content. After a proper reduction of antinutritional contents, seed powders which contain carbohydrate, protein, and premium lipids or specific extracts with excellent functional properties can be obtained. …”
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3685
Necroptotic Cell Death Signaling and Execution Pathway: Lessons from Knockout Mice
Published 2015-01-01“…Caspase-8 has a critical role in pro- and antinecrotic signaling pathways leading to the activation of receptor interacting protein kinase 1 (RIPK1), RIPK3, and the mixed kinase domain-like (MLKL) for a convergent execution pathway of necroptosis or regulated necrosis. …”
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3686
Occurrence of Fungi and Mycotoxins in Fish Feeds and Their Impact on Fish Health
Published 2019-01-01“…The growth in aquaculture has led to high demand for fish feeds, which play a very important role in fish nutrition and health. Use of animal protein in fish feeds is expensive; hence, a majority of farmers from developing countries use local feed ingredients from plant origin as a source of dietary protein. …”
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3687
Mineral Properties and Dietary Value of Raw and Processed Stinging Nettle (Urtica dioica L.)
Published 2013-01-01“…Results show that processed nettle can supply 90%–100% of vitamin A (including vitamin A as β-carotene) and is a good source of dietary calcium, iron, and protein. We recommend fresh or processed nettle as a high-protein, low-calorie source of essential nutrients, minerals, and vitamins particularly in vegetarian, diabetic, or other specialized diets.…”
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3688
Sequential Treatment with Activin and Hepatocyte Growth Factor Induces FOXM1 to Promote Colorectal Cancer Liver Metastasis
Published 2022-01-01“…Activin alone increased the mRNA and protein expression of FOXM1. In contrast, HGF alone enhanced the phosphorylation of FOXM1, without altering the total protein level of FOXM1. …”
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3689
Lipoxins and Annexin-1: Resolution of Inflammation and Regulation of Phagocytosis of Apoptotic Cells
Published 2006-01-01“…LXA4 and ATLs elicit cellular responses by interacting with a G protein -coupled receptor (ALXR) that is expressed in various cell types. …”
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3690
Complete chloroplast genome of Sagina maxima A. Gray (Caryophyllaceae) from Ulleung-do Island, Korea
Published 2024-12-01“…A unique set of 112 genes were identified which includes 78 protein-coding genes, 30 tRNA and 4 rRNA. Total 18 genes were duplicated within the IR regions and 16 genes have one intron and only clpP gene with two introns. …”
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3691
The Pivotal Immunomodulatory and Anti-Inflammatory Effect of Histone-Lysine N-Methyltransferase in the Glioma Microenvironment: Its Biomarker and Therapy Potentials
Published 2021-01-01“…The amino acid succession of EZH2 protein makes it appropriate for covalent modifications, like phosphorylation, acetylation, O-GlcNAcylation, methylation, ubiquitination, and sumoylation. …”
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3692
Role of BMP-4 and Its Signaling Pathways in Cultured Human Melanocytes
Published 2009-01-01“…Bone Morphogenetic Protein (BMP-4) was shown to down-regulate melanogenesis, in part, by decreasing the level of tyrosinase [Yaar et al. (2006) JBC:281]. …”
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3693
Protective Effects of Gemigliptin, a Dipeptidyl Peptidase-4 Inhibitor, against Cisplatin-Induced Nephrotoxicity in Mice
Published 2017-01-01“…In addition, gemigliptin increased the protein expression of heme oxygenase-1 (HO-1) and NAD(P)H:quinone oxidoreductase 1 (NQO1) in the kidneys of cisplatin-treated mice. …”
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3694
Potential Therapeutic Drugs for Parkinson’s Disease Based on Data Mining and Bioinformatics Analysis
Published 2018-01-01“…Method differential gene candidates were obtained based on data mining of genes of PD brain tissue, original gene data analysis, differential gene crossover, pathway enrichment analysis, and protein interaction, and potential therapeutic drugs for Parkinson’s disease were obtained through drug-gene relationship. …”
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3695
Protocol for profiling RNA m5C methylation at base resolution using m5C-TAC-seq
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3696
Exploring how papaya juice improves meat tenderness and digestive characteristics in Wenchang chickens
Published 2025-01-01“…Compared with that in the control group, the tenderness of Wenchang chicken meat decreased and the protein solubility increased with the increase in papaya juice concentration. …”
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3697
Immunoinformatics Identification of B- and T-Cell Epitopes in the RNA-Dependent RNA Polymerase of SARS-CoV-2
Published 2021-01-01“…Further, physicochemical properties, allergenicity, toxicity, and stability of RdRp protein were evaluated to demonstrate the specificity of the epitope candidates. …”
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3698
Distinct Molecular Effects of Angiotensin II and Angiotensin III in Rat Astrocytes
Published 2013-01-01“…Previously, we showed that Ang II and Ang III induced mitogen-activated protein (MAP) kinases ERK1/2 and stress-activated protein kinase/Jun-terminal kinases (SAPK/JNK) phosphorylation in cultured rat astrocytes. …”
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3699
Characterizing agronomic, morphological, nutritional, and phytochemical traits of local sorghum (Sorghum bicolor L.) in Indonesia
Published 2024-07-01“…Nutritional analysis revealed that local Tritiro sorghum contains 10.11% protein, 0.19% fat, 86.73% carbohydrates, 68.97% starch, and 9.43 mg g⁻¹ tannins. …”
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3700
xCT as a potential marker for neuroendocrine cells in high-risk prostate cancer and the relation to AL122023.1-miR-26a/30d/30e axis.
Published 2025-01-01“…However, miR-26a/-30d/-30e did not inhibit xCT expression at protein level. Nevertheless, indirect inhibitory effect of AL122023.1 on the xCT expression could be shown. …”
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