The WAVE complex in developmental and adulthood brain disorders by Hyung-Goo Kim, Clara Berdasco, Angus C. Nairn, Yong Kim

“…The orchestrated organization of actin filaments is controlled by various actin regulatory proteins. Wiskott‒Aldrich syndrome protein-family verprolin-homologous protein (WAVE) members are key activators of ARP2/3 complex-mediated actin polymerization. …”
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A Novel Heterozygous De Novo MORC2 Missense Variant Causes an Early Onset and Severe Neurodevelopmental Disorder by Daniel Arbide, Nour Elkhateeb, Ewa Goljan, Carolina Perez Gonzalez, Anna Maw, Soo-Mi Park

“…Microrchidia CW-type zinc finger protein 2 (MORC2) is an ATPase-containing nuclear protein which regulates transcription through chromatin remodelling and epigenetic silencing. …”
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EFFECT OF REPRODUCTIVE STAGES ON SOME BLOOD METABOLITES IN THE SHOW AND RACEHORSE MARES IN IRAQ by M. A. Abed, T. A. Abdulkareem, W. A. Saleh

“…The racehorse mares exhibited higher (P≤0.05) serum concentrations of total protein than those of the showhorse mares. For both types, serum total protein was higher (P≤0.05) in the first and last month than in the post-foaling period. …”
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A Case of an Elderly Woman Who Developed Corneal Perforation in the Clinical Course of Myeloperoxidase Positive Antineutrophil Cytoplasmic Antibody-Associated Vasculitis by Shuhei Kobayashi, Makoto Harada, Aiko Yamada, Yasuhiro Iesato, Koji Hashimoto, Yuji Kamijo

“…AAV can cause various ocular manifestations. Although C-reactive protein and ANCA titers are useful markers of disease activity and the relapse of AAV complications, including ocular lesions, these markers do not always increase at the time of worsening ocular lesions. …”
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Mechanism of Gene Amplification via Yeast Autonomously Replicating Sequences by Shelly Sehgal, Sanjana Kaul, M. K. Dhar

“…The gene amplification assays showed that plasmid bearing APS from yeast and human beings led to enhanced protein concentration as compared to the wild type. …”
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A Molecular and Whole Body Insight of the Mechanisms Surrounding Glucose Disposal and Insulin Resistance with Hypoxic Treatment in Skeletal Muscle by R. W. A. Mackenzie, P. Watt

“…Indeed, hypoxia has been widely implicated in the development of insulin resistance either via the direct action on insulin receptor substrate (IRS) and protein kinase B (PKB/Akt) or indirectly through adipose tissue expansion and systemic inflammation. …”
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Regulation of Annexin I in Rheumatoid Synovial Cells by Glucocorticoids and Interleukin-1 by Eric F. Morand, Pam Hall, Paul Hutchinson, Yuan H. Yang

“…DEX increased FLS annexin I protein translocation and mRNA expression. Interleukin (IL)-1β also induced annexin I translocation and mRNA but also increased intracellular protein. …”
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Influence of AGTR1 and ABCB1 Gene Polymorphism on the Curative Effect of Irbesartan by Qiao Wang, Lingsen You, Zeyu Li, Leiyi Zhang, Xueqi Li, Xuesong Yang

“…Eventually, we assumed that the different drug responses of irbesartan among various AGTR1 genotypes were due to the diversity of the irbesartan-conjugated protein, which is responsible for crossing-coupled intracellular G-protein-coupled receptors (GPCRs).…”
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Laboratory Markers in the Prediction of Acute Perforated Appendicitis in Children by Jing Yang, Chong Liu, Yuxia He, Zhangqiao Cai

“…White blood cell count with C-reactive protein and neutrophils percentage with CRP are important markers in distinguishing perforated appendicitis from nonperforated appendicitis in pediatric subjects.…”
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Application of Chemically Modified and Unmodified Waste Biological Sorbents in Treatment of Wastewater by John Kanayochukwu Nduka

“…Protein wastes (feathers, goat hair) and cellulosic wastes (corn cob, coconut husks) were collected and washed with detergent solution, thoroughly rinsed and sun dried for 2 days before drying in an oven, and then ground. …”
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Chlorogenic acid complex (CGA7), standardized extract from green coffee beans exerts anticancer effects against cultured human colon cancer HCT-116 cells by K. Gouthamchandra, H.V. Sudeep, B.J. Venkatesh, K. Shyam Prasad

“…Further, CGA7 induced apoptosis was characterized by DNA fragmentation, PARP-1 cleavage, caspase-9 activation, and down regulation of Bcl-2, an anti-apoptotic protein and up regulation of pro-apoptotic protein BAX. …”
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Signature Prediction Modeling in Cytolethal Distending Toxin-Producing Strains by Maryam Javadi, Mana Oloomi, Saeid Bouzari

“…The identified signatures include several individual phage proteins (holins, nucleases, and terminases, and transferases) and multiple members of different protein families (the lambda family, phage-integrase family, phage-tail tape protein family, putative membrane proteins, regulatory proteins, restriction-modification system proteins, tail fiber-assembly proteins, base plate-assembly proteins, and other prophage tail-related proteins). …”
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Productive Entry Pathways of Human Rhinoviruses by Renate Fuchs, Dieter Blaas

“…Upon uptake into acidic compartments, the icosahedral HRV capsid expands by ~4% and holes open at the 2-fold axes, close to the pseudo-3-fold axes and at the base of the star-shaped dome protruding at the vertices. RNA-protein interactions are broken and new ones are established, the small internal myristoylated capsid protein VP4 is expelled, and amphipathic N-terminal sequences of VP1 become exposed. …”
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sNASP Mutation Aggravates to the TLR4-Mediated Inflammation in SLE by TAK1 Pathway by Yatao Bao, Meng Lian, Yong Chen, Xiaotian Gu, Kunyu Cao, Xiaoping Du, Jiyu Ju

“…In previous studies, we found that the mutant somatic nuclear autoantigenic sperm protein (sNASP) gene in the mouse lupus susceptibility locus Sle2 can promote the development of lupus model mice, but the mechanism is still unclear. …”
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Theoretical investigation on models of circadian rhythms based on dimerization and proteolysis of PER and TIM by Jifa Jiang, Qiang Liu, Lei Niu

“…By imposing assumptions that the dimerization reactions were fast and dimeric proteins were in rapid equilibrium, they reduced the model to a pair of nonlinear ordinary differential equations of mRNA and total protein concentrations. …”
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Aloe vera leaves potential as a new source of transglutaminase by Cahyo Indarto, Supriyanto Supriyanto, Wahyu Prihanta, Dang Ngoc Hung

“…Transglutaminase is an enzyme that catalyzes cross-linking reactions between primary protein chains. This activity can be applied to improve the texture quality of protein-based food products, such as meatballs, and surimi sausage. …”
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Performance Enhancing Diets and the PRISE Protocol to Optimize Athletic Performance by Paul J. Arciero, Vincent J. Miller, Emery Ward

“…In addition, timed-daily protein (P) intake has become a hallmark for all athletes. …”
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Chronic asymptomatic orchitis in dogs alters Sertoli cell number and maturation status by Pauline Rehder, Eva-Maria Packeiser, Hanna Körber, Sandra Goericke-Pesch

“…Sertoli cells also partly returned to an immature status, as indicated by the expression of AMH and CK18 at mRNA and protein levels. The degree of spermatogenesis disruption matched with the degree of Sertoli cell alterations. …”
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Modelling Peroxisomal Disorders in Zebrafish by Chenxing S. Jiang, Michael Schrader

“…Their biogenesis relies on several peroxins (encoded by <i>PEX</i> genes), which mediate matrix protein import, membrane assembly, and peroxisome multiplication. …”
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Selective Sensing of Tyrosine Phosphorylation in Peptides Using Terbium(III) Complexes by Jun Sumaoka, Hiroki Akiba, Makoto Komiyama

“…Phosphorylation of tyrosine residues in proteins, as well as their dephosphorylation, is closely related to various diseases. …”
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