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3441
The Response of Corneal Endothelial Cells to Shear Stress in an In Vitro Flow Model
Published 2021-01-01“…The expression of the corneal endothelium-related markers ZO-1, N-cadherin, and Na+-K+-ATPase in rabbit corneal endothelial cells (RCECs) was upregulated at both the mRNA and protein levels after exposure to shear stress. Conclusion. …”
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3442
Aluminum Poisoning with Emphasis on Its Mechanism and Treatment of Intoxication
Published 2022-01-01“…Aluminum poisoning has complex and multidimensional effects, such as disruption or inhibition of enzymes activities, changing protein synthesis, nucleic acid function, and cell membrane permeability, preventing DNA repair, altering the stability of DNA organization, inhibition of the protein phosphatase 2A (PP2A) activity, increasing reactive oxygen species (ROS) production, inducing oxidative stress, decreasing activity of antioxidant enzymes, altering cellular iron homeostasis, and changing NF-kB, p53, and JNK pathway leading to apoptosis. …”
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3443
Proximate Composition of Thai and Cambodian Ready-to-Eat Insects
Published 2021-01-01“…The combination of high fat and protein with low carbohydrates makes them suitable to combat nutrition disorders.…”
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3444
Accelerated enzyme engineering by machine-learning guided cell-free expression
Published 2025-01-01“…Our ML-guided, cell-free framework promises to accelerate enzyme engineering by enabling iterative exploration of protein sequence space to build specialized biocatalysts in parallel.…”
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3445
Ursodeoxycholic Acid Attenuates Endoplasmic Reticulum Stress-Related Retinal Pericyte Loss in Streptozotocin-Induced Diabetic Mice
Published 2017-01-01“…Additionally, induction of ER stress and the unfolded protein response (UPR) were assessed in diabetic mice and human retinal pericytes exposed to advanced glycation end products (AGE) or modified low-density lipoprotein (mLDL). …”
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3446
Protocol to generate dual-target compounds using a transformer chemical language model
Published 2025-03-01“…Summary: Here, we present a protocol to generate dual-target compounds (DT-CPDs) interacting with two distinct target proteins using a transformer-based chemical language model. …”
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3447
Analysis of Chemical Constituents Changing in Physical Process and Nutritional Components of Malus halliana Koehne Tea
Published 2017-01-01“…The contents of crude protein and the crude fat were measured by spectrophotometric detection and soxhlet extraction detection, respectively. …”
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3448
Unveiling the Molecular Architecture of HBV Spherical Subviral Particles: Structure, Symmetry, and Lipid Dynamics
Published 2024-12-01“…Recent advances in cryo-electron microscopy (cryo-EM) have uncovered the heterogeneity and dynamic nature of spherical HBV SVPs, emphasizing the essential role of lipid–protein interactions in maintaining particle stability. …”
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3449
The haematological influences of seaweed extract on growing japanese quails
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3450
Colloidal nanoparticles prepared from zein and casein: interactions, characterizations and emerging food applications
Published 2023-03-01“…Food scientists are inspired by naturally occurring proteins to induce self-assembly behavior of protein by manipulating environmental parameters, providing opportunities to construct special and expected NPs. …”
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3451
In Vitro Characterization of Motor Neurons and Purkinje Cells Differentiated from Induced Pluripotent Stem Cells Generated from Patients with Autosomal Recessive Spastic Ataxia of...
Published 2023-01-01“…The disease is caused by mutations in the SACS gene leading in most cases to a loss of function of the sacsin protein, which is highly expressed in motor neurons and Purkinje cells. …”
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3452
Nutritional Properties and Antinutritional Factors of Corn Paste (Kutukutu) Fermented by Different Strains of Lactic Acid Bacteria
Published 2015-01-01“…The principal component analysis (PCA) shows that, for a best reduction of antinutrients factors and improvement of protein content and minerals, Kutukutu must be fermented by L. brevis G25 and L. fermentum N33, respectively. …”
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3453
Stochastic modelling of PTEN regulation in brain tumors: A model for glioblastoma multiforme
Published 2015-05-01“…Our model also covers protein formation and the backward mechanism going from the protein back to the miRNA.The numerical simulations show that the model reproduces the expected dynamics of normal glial cells. …”
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3454
Protective Effect of Acacia nilotica (L.) against Acetaminophen-Induced Hepatocellular Damage in Wistar Rats
Published 2013-01-01“…Further, pretreatment with extract elevated the total protein and GSH level and decreased the level of LPO. …”
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3455
Postsynaptic Signals Mediating Induction of Long-Term Synaptic Depression in the Entorhinal Cortex
Published 2008-01-01“…Okadaic acid, which blocks activation of protein phosphatases 1 and 2a, also prevented LTD. …”
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3456
A Review: Application of Bromelain Enzymes in Animal Food Products
Published 2023-09-01“…In animal food products, bromelain is applied as a meat tenderizer, making of protein hydrolyzate products, cheese and also fish sauce product. …”
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3457
Senyawa Fucodiphlorethol Dan Phloroglucinol Alga Coklat Sebagai Inhibitor Lipase Secara In Silico
Published 2022-05-01“…Lipase structure (PDB ID 1ETH) was obtained from protein data bank and docked with fucodiphlorethol and phloroglucinol in specific position. …”
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3458
Astragaloside IV Treats Parkinson’s Disease by Regulating the Proliferation and Differentiation of NSCs through the SHH–Nurr1 Pathway
Published 2024-01-01“…Two factors, sonic hedgehog (SHH) and nuclear receptor–related 1 protein (Nurr1), have been identified as influential in NSCs differentiation. …”
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3459
The Reporter System for GPCR Assay with the Fission Yeast Schizosaccharomyces pombe
Published 2012-01-01“…G protein-coupled receptors (GPCRs) are associated with a great variety of biological activities. …”
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3460
The Role of TLR2, TLR4, and TLR9 in the Pathogenesis of Atherosclerosis
Published 2016-01-01“…TLRs recruit adaptor molecules, including myeloid differentiation primary response protein (MYD88) and TIRF-related adaptor protein (TRAM), to mediate activation of MAPKs and NF-kappa B pathways. …”
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