Association of p53 with Neurodegeneration in Parkinson’s Disease by Qiang Luo, Wei Sun, Yi-Fan Wang, Ji Li, Da-Wei Li

“…p53 is a vital transcriptional protein implicated in regulating diverse cellular processes, including cell cycle arrest, DNA repair, mitochondrial metabolism, redox homeostasis, autophagy, senescence, and apoptosis. …”
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Spidroin-Based Biomaterials in Tissue Engineering: General Approaches and Potential Stem Cell Therapies by Qi Zhang, Min Li, Wenbo Hu, Xin Wang, Jinlian Hu

“…Herein, we present an overview of the recent advances in spider silk protein that fabricate biomaterials for tissue engineering and regenerative medicine. …”
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Congenital Lipoid Adrenal Hyperplasia, as a Poorly Understood Cause of 46 XY Sexual Differentiation Disorder by Raúl Villanueva Rodríguez, Alberto Vielma Valdez, Maricruz Cassou Martinez, Laura Leticia Pérez Corrales, Ramón G. de los Santos Aguilar, Luis David Sol Oliva

“…The genetic study found a steroidogenic acute regulatory protein (StAR) mutation. Conclusion. Mutations in StAR result in a nonfunctional protein, which clinically translates into congenital adrenal hyperplasia and, in the case of patients with 46 XY karyotype, is accompanied by gonadal dysgenesis characterized by androgen deficiency, without alterations in anti-Müllerian hormone.…”
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The Precapillary Segment of the Blood-Brain Barrier and Its Relation to Perivascular Drainage in Alzheimer's Disease and Small Vessel Disease. by Dietmar R. Thal

“…The blood-brain barrier (BBB) is the border between the brain tissue and the blood and consists of a pre- and post-capillary and a capillary segment. At capillaries protein transport is possible via receptor-mediated endocytosis through endothelial cells. …”
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AM3, an Oral BRM: Protective Agent against Iatrogenic Bone-Marrow and Liver Damage in Breast Cancer Patients under Conventional Adjuvant Radiochemotherapy by Vicente G Villarrubia, Paula Marquez, Jose Cobo, Guillermo J Sada

“…In five clinical trials AM3, a polysaccharide/protein biological response modifier, was given (3 g/day; two capsules, tid) to 79 breast cancer patients undergoing adjuvant radio- and/or chemotherapies. …”
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Linking Neuroinflammation and Neurodegeneration in Parkinson’s Disease by Géraldine Gelders, Veerle Baekelandt, Anke Van der Perren

“…Nevertheless, several questions remain unanswered regarding the role of misfolded protein aggregates and the cause of neuronal cell death. …”
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Investigation Of The Relation Between Additive Commonly Used In Meat Products - Soy And Meat By Fluorescence Spectroscopy by Z. Ozbekova, A. Kulmyrzaev

“…Chemical characteristics were also determined including humidity, fat and protein content. The obtained experimental data have been processed with chemometrics methods such as PCA, PLSDA and PLS. …”
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Low concentrations of Lactobacillus rhamnosus GG ( Yoba®) are safe in male Drosophila melanogaster by Keneth Iceland, Kasozi, Aisha, Bukenya, Ejike, Daniel Eze, Josephine, Kasolo, Dickson Stuart, Tayebwa, Fred, Ssempijja, Joy, Suubo, Andrew, Tamale, Isaac, Echoru, Ibrahim, Ntulume, Sarah Kemuma, Onkoba, Lisa Nkatha, Micheni, Emmanuel Tiyo, Ayikobua, Oscar Hilary, Asiimwe, Muhamudu, Kalange

“…The study assessed male w1118 Drosophila melanogaster which were provided food supplemented with Yoba ® at 1%, 3%, 6%, and 12% on motor function, total protein, catalase activity, and hydrogen peroxide scavenging activity and lifespan. …”
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Increased Fas and Bcl-2 Expression on Peripheral Blood T and B Lymphocytes from Juvenile-Onset Systemic Lupus Erythematosus, but not from Juvenile Rheumatoid Arthritis and Juvenile... by Bernadete L. Liphaus, Maria H. B. Kiss, Solange Carrasco, Claudia Goldenstein-Schainberg

“…Defective regulation of apoptosis may play a role in the development of autoimmune diseases. Fas and Bcl-2 proteins are involved in the control of apoptosis. …”
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A Cross-Sectional Analysis of Dietary Intake and Nutritional Status of Patients on Haemodialysis Maintenance Therapy in a Country of Sub-Saharan Africa by Nyangi A. Gityamwi, Kathryn H. Hart, Barbara Engel

“…More than 70% of participants had suboptimal measures for protein and energy intake, dietary iron, serum albumin, muscle mass, and hand grip strength (HGS). …”
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CDC25B Is a Prognostic Biomarker Associated With Immune Infiltration and Drug Sensitivity in Hepatocellular Carcinoma by Zixiang Huang, Liangzhi Xu, Zhengqiang Wu, Xiaofeng Xiong, Linfei Luo, Zhili Wen

“…CDC25B expression was verified in clinical HCC tissue samples using fluorescence quantitative polymerase chain reaction (q-PCR) and protein immunoblotting (Western blot). Gene set enrichment analysis (GSEA) was used to identify signaling pathways enriched in CDC25B expression, and differential genes (DEGs) were used to screen out coexpressed hub genes and construct protein-protein interaction (PPI) networks. 5-Ethynyl-2′-deoxyuridine (EDU) staining was used to compare the proliferation and differentiation ability of the HCC cell line (HCC-LM3) after knockdown of CDC25B. …”
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Fimasartan Ameliorates Nonalcoholic Fatty Liver Disease through PPARδ Regulation in Hyperlipidemic and Hypertensive Conditions by Yong-Jik Lee, Yoo-Na Jang, Yoon-Mi Han, Hyun-Min Kim, Jong-Min Jeong, Hong Seog Seo

“…In HepG2 cells and liver tissues, fimasartan was shown to increase the protein levels of peroxisome proliferator-activated receptor delta (PPARδ), phosphorylated 5′ adenosine monophosphate-activated protein kinase (p-AMPK), phosphorylated acetyl-CoA carboxylase (p-ACC), malonyl-CoA decarboxylase (MCD), medium chain acyl-CoA dehydrogenase (MCAD), and peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α), and it led to a decrease in the protein levels of 11 beta-hydroxysteroid dehydrogenase 1 (11β-HSDH1), fatty acid synthase (FAS), and tumor necrosis factor-alpha (TNF-α). …”
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Moringa oleifera seed meal as a sustainable fishmeal substitute: Growth and health implications for Cirrhinus mrigala by Sadia Tabassum, Syed Makhdoom Hussain, Shafaqat Ali, Pallab K. Sarker, Khalid A. Al-Ghanim, Lalarukh

“…As global protein demands rise, fish protein has become an essential component of food security. …”
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Effects of Ghrelin on Triglyceride Accumulation and Glucose Uptake in Primary Cultured Rat Myoblasts under Palmitic Acid-Induced High Fat Conditions by Lingling Han, Jia Li, Ying Chen, Wei Wang, Dan Zhang, Guoliang Liu

“…The glucose transporter 4 (GLUT4), AMP-activated protein kinase (AMPK), acetyl-CoA carboxylase (ACC), and uncoupling protein 3 (UCP3) were assessed by RT-PCR and western blot. …”
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IL-21 Receptor Expression in Human Tendinopathy by Abigail L. Campbell, Nicola C. Smith, James H. Reilly, Shauna C. Kerr, William J. Leach, Umberto G. Fazzi, Brian P. Rooney, George A. C. Murrell, Neal L. Millar

“…We found significantly elevated expression of IL-21 receptor message and protein in human tendon samples but found no convincing evidence of the presence of IL-21 at message or protein level. …”
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Pathway Analysis of Metabolic Syndrome Using a Genome-Wide Association Study of Korea Associated Resource (KARE) Cohorts by Unjin Shim, Han-Na Kim, Yeon-Ah Sung, Hyung-Lae Kim

“…Through pathway analysis of MetS, pathways related with PDGF, mitogen-activated protein kinase, and PPAR signaling, as well as nucleic acid binding, protein secretion, and DNA repair, were identified. …”
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Representing and Quantifying Conformational Changes of Kinases and Phosphatases Using the TSR-Based Algorithm by Tarikul I. Milon, Krishna Rauniyar, Sara Furman, Khairum H. Orthi, Yingchun Wang, Vijay Raghavan, Wu Xu

“…Protein kinases and phosphatases are key signaling proteins and are important drug targets. …”
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Long-term Conservative Follow-up in Children with High-grade Vesicoureteral Reflux and an Abnormal Dimercaptosuccinic Acid Scan by Pankaj V Deshpande

“…All children have normal growth, kidney function, urine protein/creatinine ratio, and blood pressure at present. (15 years follow-up in 17 children). …”
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Mechanistic Insights into the Anticancer Potential of Methoxyflavones Analogs: A Review by Mohammad Aidiel, Maisarah Abdul Mutalib, Rajesh Ramasamy, Nik Nasihah Nik Ramli, Shirley Gee Hoon Tang, Siti Hajar Adam

“…The methoxy group in naturally occurring flavones promotes cytotoxic activity in various cancer cell lines by targeting protein markers, in facilitating ligand–protein binding mechanisms and activating cascading downstream signaling pathways leading to cell death. …”
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PTPIP51: A New Interaction Partner of the Insulin Receptor and PKA in Adipose Tissue by M. A. Bobrich, S. A. Schwabe, A. Brobeil, M. Viard, M. Kamm, F. C. Mooren, K. Krüger, C. Tag, M. Wimmer

“…Our previous experiments revealed an association of PTPIP51 (protein tyrosine phosphatase interacting protein 51) with the insulin signalling pathway through PTP1B and 14-3-3beta. …”
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