Identification of KRT16 and ANXA10 as cell cycle regulation genes for lung adenocarcinoma based on self-transcriptome sequencing of surgical samples and TCGA public data mining by Wen-jian Liu, Jia-pan Shen, Ren-quan Zhang, Xiao-yun Fan

“…The expression was validated at mRNA and protein levels, and the gene knockdown was used to examine the impact and underlying mechanisms on lung cancer cells. …”
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Human Neutrophil Defensins Disrupt Liver Interendothelial Junctions and Aggravate Sepsis by QiXing Chen, Yang Yang, YiHang Pan, LiHua Shen, Yan Zhang, Fei Zheng, Qiang Shu, XiangMing Fang

“…Human neutrophil peptides 1-3 (HNP1-3), also known as human α-defensins, are the most abundant neutrophil granule proteins. The genes that encode HNP1-3, DEFA1/DEFA3, exhibit extensive copy number variations, which correlate well with their protein levels. …”
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Gene Expression Profiling of the Sciatic Nerve in Streptozotocin-Induced Diabetic Rats with Peripheral Neuropathy by Yiji Tu, Zenggan Chen, Feng Zhang, Zhenglin Di, Junhui Zhang, Li Cai

“…DEGs from the 3 most highly connected clusters in the protein-protein interaction network were enriched for biological processes or pathways such as “cell division,” “cell cycle,” “protein phosphorylation,” “chemokine signaling pathway,” “neuropeptide signaling pathway,” “response to drug,” “cellular response to insulin stimulus,” “PPAR signaling pathway,” and “glycerophospholipid metabolism.” …”
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Development of sugar- and fat-reduced pulse cookies with improved predicted glycemic behavior by Xinying Suo, Marianna Tagliasco, Matteo Bonfini, Laura Bonfili, Oscar Moreno Araiza, Anna Baggio, Anna Maria Eleuteri, Nicoletta Pellegrini, Elena Vittadini

“…Developed cookies had higher protein and fiber contents, reduced sugar (∼45 - 50 % reduction), and saturated fats (∼77 - 80 % reduction) and also had a lower predicted glycemic index compared to traditional cookies. …”
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Contemporary nutrition-based interventions to reduce risk of infection among elderly long-term care residents: A scoping review. by Athanasios Psihogios, Claudia Madampage, Brent E Faught

“…Probiotic and soy-based protein interventions did not significantly affect risk of infection or lymphocyte parameters, respectively.…”
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CD36-Mediated Lipid Accumulation and Activation of NLRP3 Inflammasome Lead to Podocyte Injury in Obesity-Related Glomerulopathy by Jing Zhao, Hong-liang Rui, Min Yang, Li-jun Sun, Hong-rui Dong, Hong Cheng

“…The expression of adipose differentiation-related protein (ADRP), CD36, sterol regulatory element-binding protein 1 (SREBP-1), and peroxisome proliferator-activated receptor α (PPARα) in renal tissue were increased. …”
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Immunoassay–mass spectrometry to identify Brucella melitensis by Amirreza Sharif, Ramin Bagheri Nejad, Alireza Ghassempour

“…Rabbits were used to manufacture brucella antibodies, which have effectively adsorbed onto the MNPs–protein A. Any particular Brucella bacteria found in the media might be absorbed by this MNPs–protein A–antibody immunoprobe. …”
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Impact of Tat Genetic Variation on HIV-1 Disease by Luna Li, Satinder Dahiya, Sandhya Kortagere, Benjamas Aiamkitsumrit, David Cunningham, Vanessa Pirrone, Michael R. Nonnemacher, Brian Wigdahl

“…The viral transactivator protein Tat plays an important role in transcriptional activation of HIV-1 gene expression. …”
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Prognostic Value of Metastatic Tumoral Caveolin-1 Expression in Patients with Resected Gastric Cancer by Der Sheng Sun, Soon Auck Hong, Hye Sung Won, Su Hyun Yoo, Han Hong Lee, Okran Kim, Yoon Ho Ko

“…High expression of Cav-1 protein of the GC in the stomach and metastatic lymph node was 12.4% (18/145) and 16.5% (15/91). …”
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Data-independent LC-MS/MS analysis of ME/CFS plasma reveals a dysregulated coagulation system, endothelial dysfunction, downregulation of complement machinery by Massimo Nunes, Mare Vlok, Amy Proal, Douglas B. Kell, Etheresia Pretorius

“…We identified 24 proteins that are significantly increased in the ME/CFS group compared to the controls, and 21 proteins that are significantly downregulated. …”
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Conditional knockdown of hepatic PCSK9 ameliorates high-fat diet-induced liver inflammation in mice by Xue-Ying Zhang, Qing-Qing Lu, Yan-Jie Li, Shan-Rui Shi, Chao-Nan Ma, Miao Miao, Shou-Dong Guo

“…Mechanistically, conditional knockdown of hepatic PCSK9 significantly reduced the levels of pro-inflammatory factors by downregulating the expression of Toll-like receptors, mitogen-activated protein kinase (MAPK), and phosphoinositide-3 kinase/protein kinase B, which subsequently attenuated the expression of downstream molecules, namely nuclear factor kappa-B and activator protein-1. …”
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Genistein Protects against Spinal Cord Injury in Mice by Inhibiting Neuroinflammation via TLR4-Mediated Microglial Polarization by Xin-Wu Li, Peng Wu, Jian Yao, Kai Zhang, Gen-Yang Jin

“…Genistein treatment reduced apoptosis by increasing Bcl2 protein expression and decreasing Bax and caspase 3 protein expression. …”
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Portable optical spectroscopy and machine learning techniques for quantification of the biochemical content of raw food materials by Cosimo Ricci, Agata Gadaleta, Annamaria Gerardino, Angelo Didonna, Giuseppe Ferrara, Francesca Romana Bertani

“…The aim of this study is to facilitate quantitative evaluation of protein content in the seeds of cereals (Triticum turgidum var. durum and Tritordeum genotypes) and ripening pomegranate fruits (Wonderful cultivar). …”
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Comparative proteomic analysis of astrocytoma tissues from patients with and without seizures by Thanakorn Khaosuwan, Kittinun Leetanaporn, Pongsakorn Choochuen, Raphatphorn Navakanitworakul, Anukoon Kaewborisutsakul, Thara Tunthanatip, Surasak Sangkhathat, Wararat Chiangjong, Kanitpong Phabphal

“…We detected 131 differentially expressed proteins (42 upregulated and 89 downregulated). Proteins upregulated in patients with seizures were mostly related to an increase in energy metabolism. …”
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p104 Binds to Rac1 and Reduces Its Activity during Myotube Differentiation of C2C12 Cell by Ki Young Choi, Min Sup Lee, Young Jun Cho, Myong Ho Jeong, Seung Jin Han, Seung Hwan Hong

“…The p104 protein inhibits cellular proliferation when overexpressed in NIH3T3 cells and has been shown to associate with p85α, Grb2, and PLCγ1. …”
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Identification and validation of depression-associated genetic variants in the UK Biobank cohort with transcriptome and DNA methylation analyses in independent cohorts by Muataz S. Lafta, Aleksandr V. Sokolov, Gull Rukh, Helgi B. Schiöth

“…The present study aimed to identify independent genetic variants in the protein-coding genes that associate with depression and to analyze their transcriptomic and methylation profile. …”
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Effect of Dry Heat Puffing on Nutritional Composition, Fatty Acid, Amino Acid and Phenolic Profiles of Pseudocereals Grains by Paucar-Menacho Luz María, Dueñas Montserrat, Peñas Elena, Frias Juana, Martínez-Villaluenga Cristina

“…Popped kiwicha showed increased protein and lipid contents and lower contents of carbohydrates compared to the untreated grains. …”
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Naoxintong Is Involved in the Coagulation Regulation of Warfarin Through the MAPK Pathway by Luo X, Chen L, Xu J, Li J

“…Cytoscape software was applied to construct the “drug-target”network; the protein interaction network (PPI) was used to study the protein-protein interaction. …”
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Effect of rutin on the structural and functional properties of ovalbumin by Qian Cui, Yanqiu Ma, Xue Mao, Guozhi Zhao, Siyi Huang, Xingyu Wen, Zimeng Zhu, Xin Gao

“…Phenolic substances affect protein functionality. This study aimed to examine how rutin influences the gel properties, antioxidant activity, and structure of ovalbumin (OVA). …”
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Inhibition of Cathepsin S Produces Neuroprotective Effects after Traumatic Brain Injury in Mice by Jianguo Xu, Handong Wang, Ke Ding, Xinyu Lu, Tao Li, Jiawei Wang, Chunxi Wang, Jian Wang

“…In this study, we investigated the time course of CatS protein and mRNA expression and the cellular distribution of CatS in a mouse model of traumatic brain injury (TBI). …”
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