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3021
Antitumor Activities of Aqueous Cinnamon Extract on 5637 Cell Line of Bladder Cancer through Glycolytic Pathway
Published 2022-01-01“…For evaluating of aqueous extract of Cinnamon effect on glycolysis, the gene expression of epidermal growth factor receptor 2 (ErbB2), heat shock protein transcription factor1 (HSF1), and lactate dehydrogenase A (LDHA), as well as protein levels of HSF1 and LDHA, LDH activity, glucose consumption, and lactate production, were measured. …”
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3022
Plasma Markers of Oxidative Stress in Patients with Gestational Diabetes Mellitus in the Second and Third Trimester
Published 2016-01-01“…Plasma samples were analyzed for 8-iso-prostaglandin F2α (8-iso-PGF2α), advanced oxidative protein products (AOPPs), protein carbonyl (PCO), glutathione peroxidase-3 (GPX-3), and paraoxonase-1 (PON1) at 16–20 weeks, 24–28 weeks, and 32–36 weeks of gestation. …”
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3023
Chia (<i>Salvia hispanica</i>) Seed Oil Modulates the Haemato-Immunological Response, Antioxidative Status and Cytokine Gene Expression of Tropical Freshwater Teleost, <i>Labeo roh...
Published 2025-01-01“…Serum glucose, cholesterol, triglycerides, and complement reactive protein levels declined, whereas marker anti-oxidative enzymes (SOD, CAT, and GST) and protein metabolic enzymes (ALT and AST) increased (<i>p</i> < 0.05) in the lowest CSO-supplemented group. …”
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3024
Downregulation of Ezrin Suppresses Migration Potential in Cervical Cancer Cells
Published 2024-12-01“…A lower level of protein significantly reduces the motor skills of SiHa and HT-3 cervical cancer cells. …”
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3025
Enhancing proteasome activity by NMDAR antagonists explains their therapeutic effect in neurodegenerative and mental diseases
Published 2025-01-01“…In our mouse model experiment, ketamine administration notably altered brain synaptic protein profiles within two hours, significantly downregulating proteins strongly associated with Alzheimer’s and Parkinson’s diseases. …”
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3026
Integration of Kinetic Analysis of Reaction Curve with a Proper Classical Approach for Enzymatic Analysis
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3027
Characterization of Human Colorectal Cancer MDR1/P-gp Fab Antibody
Published 2013-01-01“…In this study, the peptide sized 21 kDa covering P-gp transmembrane region was first prepared for generating a novel mouse monoclonal antibody Fab fragment with biological activity against multiple drug resistance protein P-gp21 by phage display technology. Phage-displayed antibody library prepared from mice spleen tissues was selected against the recombinant protein P-gp21 with five rounds of panning. …”
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3028
The SsDREB Transcription Factor from the Succulent Halophyte Suaeda salsa Enhances Abiotic Stress Tolerance in Transgenic Tobacco
Published 2015-01-01“…Yeast one-hybrid assays showed that SsDREB protein specifically binds to the DRE sequence and could activate the expression of reporter genes in yeast, suggesting that the SsDREB protein was a CBF/DREB transcription factor. …”
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3029
A Comparative Study on Growth Performance, Body Composition, and Liver Tissue Metabolism Rearing on Soybean Lecithin-Enriched Artemia Nauplii and Microdiet in Rock Bream (Oplegnath...
Published 2023-01-01“…Retard weaning onto MD led to lower growth performance, which was likely due to the diversity of lipid and protein metabolism.…”
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3030
Quality evaluation of fermented products of various local agroindustrials by-products: the effect on digestibility and growth performance of common carp juvenile
Published 2013-11-01“…Furthermore, fermentation also increased the feed digestibility including protein, energy, and total digestibility by the tested fish, as it is shown that the use of fermented feedstuffs may increase protein digestibility 3.88‒11.73%, 2,21‒10,24%, and 3,63‒72,37%. …”
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3031
Effect of Orexin-A on Cortisol Secretion in H295R Cells via p70S6K/4EBP1 Signaling Pathway
Published 2015-01-01“…Many studies have demonstrated the ability of orexin-A to regulate adrenocortical cells through the MAPK (mitogen-activated protein kinases) pathway. The aim of our study is to investigate the effect of orexin-A on cortisol secretion via the protein 70 ribosomal protein S6 kinase-1 (p70S6K) and eukaryotic translation initiation factor 4E binding proteins (4EBP1) signaling pathway in adrenocortical cells. …”
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3032
Contrastive-learning of language embedding and biological features for cross modality encoding and effector prediction
Published 2025-02-01“…Effector predictors utilizing pre-trained protein language models (PLMs) have shown sound performance by leveraging extensive evolutionary and sequential protein features. …”
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3033
E3 Ubiquitin Ligase CHIP Inhibits the Interaction between Hsp90β and MAST1 to Repress Radiation Resistance in Non-Small-Cell Lung Cancer Stem Cells
Published 2022-01-01“…Mechanistically, CHIP promoted MAST1 ubiquitination by blocking Hsp90β interaction with MAST1, thus inhibiting MAST1 protein stability. Furthermore, CHIP-mediated downregulation of MAST1 protein stability inhibited the NSCLC stem cell properties and radiation resistance. …”
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3034
Role of Eukaryotic Initiation Factors during Cellular Stress and Cancer Progression
Published 2016-01-01“…Protein synthesis can be segmented into distinct phases comprising mRNA translation initiation, elongation, and termination. …”
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3035
Dexamethasone Suppressed LPS-Induced Matrix Metalloproteinase and Its Effect on Endothelial Glycocalyx Shedding
Published 2015-01-01“…In conclusion, activation of MMPs plays important role in regulating ZO-1 and syndecan-1 protein levels in LPS mediated endothelial perturbation. …”
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3036
Effect of Thermal Processing on Physicochemical and Antioxidant Properties of Raw and Cooked Moringa oleifera Lam. Pods
Published 2022-01-01“…Moringa oleifera Lam. pods have excellent antioxidant characteristics and are a good source of protein, carbohydrate, fat, vitamins, beta-carotene, amino acids, and phenolic compounds. …”
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3037
Cilostazol Combats Lipopolysaccharide-Induced Hippocampal Injury in Rats: Role of AKT/GSK3β/CREB Curbing Neuroinflammation
Published 2024-01-01“…Cilostazol treatment also restored the decreased phosphorylation of protein kinase B (p-AKT) and reduced the elevated levels of phosphorylated glycogen synthase kinase-3 beta (p-GSK3β) and cAMP response element-binding protein (CREB) in the hippocampus of LPS-treated rats. …”
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3038
Selective Activation of Cancer Stem Cells by Size-Specific Hyaluronan in Head and Neck Cancer
Published 2015-01-01“…Furthermore, our results indicate that the anti-miR-10 inhibitor not only decreases survival protein expression, but also increases chemosensitivity of the 200 kDa-HA-treated CSCs. …”
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3039
PreZon: Prediction by Zone and Its Application to Egg Productivity in Chickens
Published 2012-01-01“…The levels of four serum proteins, including apolipoprotein A-I, vitellogenin, X protein (an IGF-I-like protein), and apo VLDL-II, were measured in chickens that were 8, 14, 22, or 24 weeks old. …”
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3040
Truncated SPAG9 as a novel candidate gene for a new syndrome: Coarse facial features, albinism, cataract and developmental delay (CACD syndrome)
Published 2025-01-01“…Sanger sequencing of both families revealed perfect segregation of the identified variant in all family members. 3D protein modeling revealed substantial changes in the protein’s secondary structure. …”
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